Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Taste Buds”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,477 records · Page 82Linked to original sources
PubMed1995

Morphology of the dorsal lingual papillae in the lesser mouse deer, Tragulus javanicus.

The dorsal lingual papillae of the lesser mouse deer were studied morphologically using light and scanning electron microscopy. Four types of papillae, filiform, fungiform, vallate and foliate, were observed. Filiform papillae consisted of larger main papillae with smaller secondary papillae on their anterolateral aspects. Secondary papillae were well distributed over the anterior two-thirds of the tongue, but were very rare or absent in the posterior third. Fungiform papillae were distributed among the filiform papillae, being larger and more abundant on the tip of the tongue. Vallate papillae were round-flat or long-flat, surrounded by a prominent circular groove and a thin annular pad. An important finding was the presence of distinct and prominent foliate papillae on the posterolateral sides of the tongue. Keratinisation of the covering stratified squamous epithelium was relatively weak. Taste buds were observed in the epithelium of the fungiform, vallate and foliate papillae. The lingual papillae of the lesser mouse deer showed some characteristics that differed from those reported for domestic ruminants. These may be related to the feeding habits and the type of food eaten by this species.

Animals↗
PubMed1976

Anatomical and neurohistological observations on the tongue of 60 mm embryo of opossum, Didetphis marsupialis.

The anatomy, histology and innervation of the tongue of 60 mm embryo of opossum, Didelphis marsupialis have been described. The tongue measures 13 mm in length and 4.5 mm in breadth. The tip of the tongue is somewhat pointed and bordered by soft fringe of simple filiform papillae which are probably tactile in function. The fungiform papillae are small rounded bead-like structures scattered over the dorsum. The circumvallate papillae are three in number and arranged in an inverted V-shape. Taste buds are developed over the dorsum of fungiform papillae. The foliate papillae are concealed. The filiform papillae in various stages of development are seen over the entire dorsum. The circumvallate papillae are not fully developed. Mucous glands and their ducts are well-developed. The innervation of the tongue of 60 mm embryo of opossum is almost similar to that of other mammals. The dorsal side of the tongue is covered with thick squamous epithelium and is innervated by thick nerve fibres. The ventral surface is thin and comparatively poor in nerve supply. The skeletal muscles and connective tissue are richly innervated by thick and thin nerve fibres. A large number of ganglion cells lie singly or in irregular groups in the plexuses of the intermingling nerve fibres. The filiform papillae are heavily innervated by thick nerve fibres. Nerve elements could not be observed in the circumvallate papillae. Fungiform papillae are also provided with fine nerve fibres. A few nerve fibres and nerve bundles are seen in the gullet region.

Animals↗
PubMed1998

Immunohistochemical observation of growth-associated protein 43 (GAP-43) in the developing circumvallate papilla of the rat.

The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of these further penetrated the apical epithelium and trench wall epithelium. At least two types of GAP-43-IR structures were recognized; taste bud-related and non-gustatory GAP-43-IR neural elements. Immunoelectron microscopy revealed that GAP-43-LI was localized predominantly in the Schwann cells, and a few axons displayed GAP-43-LI in the lamina propria. In the trench epithelium, GAP-43-LI was detected in the cytoplasmic side of the axonal membrane. Some intragemmal GAP-43-IR axons made synaptic-like contacts with taste bud cells. At least four developmental stages were defined on the basis of the changes in distribution of GAP-43-LI. In stage I [embryonic day (E) 16-17] GAP-43-IR structures accumulated at the lamina propria just beneath the newly-formed circumvallate papilla. In stage II (E18-19) GAP-43-IR nerve fibers began to penetrate the apical epithelium. In stage III [E20-postnatal day (P) 0] GAP-43-IR nerve fibers first appeared in the trench wall epithelium. Penetration of GAP-IR nerve fibers occurred in the inner trench wall epithelium first, and then in the outer trench wall epithelium. In stage IV (P1-) the distribution of GAP-43-LI was similar to that observed in the adult; but the density of GAP-43-LI was much higher than in adults. PGP 9.5-LI showed a similar distribution pattern to that of GAP-43-LI, except for round-shaped cells in the apical epithelium at the late embryonic stages, and in taste bud cells and intralingual ganglionic cells which lacked GAP-43-LI. The similarities in distribution patterns of GAP-43-LI and PGP 9.5-LI during the development and mature circumvallate papilla suggest that GAP-43 may be a key neuronal molecule for induction and maintenance of the taste buds.

Animals↗
PubMed2000

A novel family of mammalian taste receptors.

In mammals, taste perception is a major mode of sensory input. We have identified a novel family of 40-80 human and rodent G protein-coupled receptors expressed in subsets of taste receptor cells of the tongue and palate epithelia. These candidate taste receptors (T2Rs) are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. Notably, a single taste receptor cell expresses a large repertoire of T2Rs, suggesting that each cell may be capable of recognizing multiple tastants. T2Rs are exclusively expressed in taste receptor cells that contain the G protein alpha subunit gustducin, implying that they function as gustducin-linked receptors. In the accompanying paper, we demonstrate that T2Rs couple to gustducin in vitro, and respond to bitter tastants in a functional expression assay.

Animals↗
PubMed2002

Receptors for bitter and sweet taste.

The identification of two families of receptors, T1Rs and T2Rs, for sweet and bitter taste stimuli has opened the door to understanding some of the basic mechanisms underlying taste transduction in mammals. Studies of the functions of these receptors and their patterns of expression provide important information regarding the detection of structurally diverse taste compounds and the manner in which different taste qualities are encoded in the mouth.

Animals↗