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[Headache and chronic sleep deprivation: an often missed relationship in children and also in adults].

Three children, two girls aged 9 and 13 years and a boy aged 9 years, and a man aged 22, presented with headache of migrainoid character. The complaints resolved after attention had been given to sleeping habits, notably problems with falling asleep. The literature on the relationship between lack of sleep and headache is scarce. In history-taking doctors often neglect sleeping customs. Yet awareness of this connection can provide the clue to a successful treatment of headache. In more than half the children with headache who are referred to the outpatient clinic of Neurology, a serious lack of sleep is a major contributing factor to the problems. One should strongly advise against use of coffee and Cola drinks at all times and of tea in the evening. Patients are urged to create a restful atmosphere about bedtime: taking a walk or a hot shower, being told a story and so on. They should not read in bed, watch TV or play computer games in the bedroom. Prescription of clonidine 0.025-0.075 mg in children before bedtime may be useful.

Adolescent↗

The relationship between selective sleep deprivation, nocturnal jaw-muscle activity and pain in healthy men.

The relationship between nocturnal jaw-muscle activity and temporomandibular disorders (TMD) is still controversial. The aim of this study was to investigate the effect of selective slow wave sleep (SWS = non-rapid-eye-movement (NREM) stage 3 + 4) deprivation on jaw-muscle activity using a new automatic system. Ten healthy men without signs of symptoms of TMD participated. The subjects slept in the laboratory for six continuous nights including one adjustment night, one baseline night, three nights with experimental sleep deprivation and one recovery night. Polysomnographic recordings of electroencephalography (EEG) and electromyography (EMG) were obtained for recognition of sleep stages and masseter muscle activity. During the three experimental nights, computer-controlled sound stimulation (60--90 dB(A), 1000 Hz) were given as long as the subjects were in SWS. Maximum voluntary occlusal force (MVOF), pain pressure threshold (PPT) and visual analogue scales (VAS) were used to assess the state of the masseter muscles every morning and evening during the study period. The results showed that the time spent in SWS was significantly decreased during the first sleep deprivation night, but there were no significant effects on nocturnal EMG activity (i.e. the numbers of bruxism episodes per hour of sleep, bruxism bursts per episodes bruxism bursts per hour of sleep), MVOF, VAS or PPT. Furthermore, the automatic system only deprived the SWS in five subjects for the following two nights although the sound stimulation was given at the maximum intensity. These results suggest that deprivation of SWS may not interact immediately with nocturnal jaw-muscle activity and jaw-muscle pain.

Adult↗

[Paradoxical sleep deprivation, stress and emotionality in the rat].

88 adult male rats were divided into 9 groups. Group I and II served as controls. The rats of group III were repeatedly aroused during 4 days at the very onset of each paradoxical sleep period by direct MRF stimulation. This deprivation reduced the daily amount of paradoxical sleep by 70%, while the slow wave sleep was reduced by 10% only. In group IV, the animals were given food and water for one hour a day only. Groups V and VI were subjected to immobilization and cold stress, respectively. Groups VII, VIII and IX were deprived of paradoxical sleep on platforms of 15, 11 and 6.5 cm in diameter, respectively. Stress was estimated by the classical Selye's triad: weight of adrenals and thymus and gastric ulceration. Emotionality was measured in the open field and also by self-stimulation of the lateral hypothalamus. Neither emotional behaviour disturbances nor stress features were found after paradoxical sleep deprivation in the group III. Moreover, this deprivation induced a slight, though significant, reduction in adrenals weight. Also, no changes in emotional behaviour were noted in the stress-exposed group V and VI. Only the interplay between REM-sleep deprivation and stress on the platforms in groups VII, VIII and especially IX led to a considerable shift in emotionality.

Animals↗