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Paradigm change and uncertainty about funding of public health research: social and scientific implications.

Since the 1970s two fundamental shifts have occurred in health research funding: a reduction in the buying power of research dollars, and an increase in the competition for resources. Most fields have also seen a decrease in the dollars available for research. Pressures for justifying the relevance of research activities have become increasingly pragmatic. The thesis of this paper is that scientific creativity and innovation are compromised by the highly uncertain and competitive funding environment of contemporary health research. This is largely because criteria of scientific excellence predicated on an investigation's presumed future impact support the status quo of methods and subject matter in funded research. Extraordinary rationality among scientists seeking and allocating resources promotes the survival of the existing system over time, yet inhibits progressive development through the transformation of conceptual models. Therefore, despite a growing unrest about the way research on population health is conducted, new conceptions of the relationship between theory and methods have been slow to emerge. Amelioration of a disjunction between the institutionalized rules governing science and the culturally sanctioned goals of science requires commitment to a dialectic between orthodoxy and dissent.

Creativity↗

The impact of environmental factors on emergency medicine resident career choice.

OBJECTIVE: To evaluate the impact of environmental factors on emergency medicine (EM) resident career choice. METHODS: Program directors of all U.S. EM residencies were surveyed in November 1997. A 22-item questionnaire assessed resources allocated to research, fellowship availability, academic productivity of faculty and residents, and career choices of residency graduates. RESULTS: The response rate was 83%. The program director (mean+/-SD) estimates of resident career choice were as follows: 27.8+/-19.1% pursued academic positions with emphasis on teaching, 5.4+/-9.8% pursued academic positions with emphasis on research, and 66.8+/-23.1%, pursued private practice positions. In addition, 5.70+/-6.13% of the residency graduates were estimated to seek fellowship training. Univariate analyses demonstrated that increasing departmental funding for research, having substantial resource availability (defined as having at least two of the following: dedicated laboratory space; support for a laboratory research technician/assistant, a clinical research nurse or study coordinator, a statistician, or an assistant with a PhD degree), a greater number of peer-reviewed publications by residents (r = 0.22; p = 0.08), and a greater number of peer-reviewed publications by faculty (r = 0.26; p = 0.04) positively correlated with the percentage of graduates who pursue academic research careers. Using multiple regression, however, increasing intramural funding and the presence of substantial resource availability were the only variables predictive of resident pursuit of an academic research career. CONCLUSION: Modification of the EM training environment may influence the career choices of graduates. Specifically, greater commitment of departmental funds and support of resources for research may enhance the likelihood of a trainee's choosing an academic research career.

Analysis of Variance↗

[Acute coronary syndromes without persistent ST-segment elevation: is risk stratification correctly applied?].

Risk stratification of patients with acute coronary syndromes is of paramount importance in achieving maximal benefit from current therapeutic modalities and for correct resource allocation. Since risk prediction based on the integration of key prognostic variables is relatively inaccurate, the clinical guidelines of the European Society of Cardiology (which have been endorsed by the Italian Federation of Cardiology) suggest an univariate approach favoring the sensitivity of the detection of high-risk patients compromising specificity. Such an approach is likely to identify a large population of high-risk patients possibly causing a mismatch between the number of patients in need of invasive evaluation and treatment, and the availability of interventional resources. Most of the risk of adverse cardiac events can be captured by the observation of three prognostic indicators: the presence of heart failure, the finding of ST-segment shifts (both elevation or depression) in the presenting electrocardiogram, and the elevation of markers of myocardial damage. The risk can be even higher in subjects who concurrently display additional risk features such as diabetes, renal insufficiency, advanced age, or previous revascularization procedures. Such patients are likely to be less treated both medically and invasively, than patients without such characteristics. The results of Italian regional registries show a favorable temporal trend toward a more a aggressive approach in such neglected high-risk subgroups.

Acute Disease↗

International movement of plasma and plasma contracting.

Plasma fractionation is a global business characterised by technological stability, increasing consolidation and a high level of regulatory oversight. All these factors affect the ease with which plasma derivatives can be accessed in the world market. As domestic regulatory measures in the first world blood economies become increasingly resonant to the precautionary approach, the availability of plasma as a raw material, as well as its cost, become an increasingly significant component in the cost of the final product. This decreases the amount of plasma which fractionators are able to allocate for export activities. Also, regulatory standards in the country of manufacture will reflect priorities in that country which may not be similar to those in export markets, but which will affect entry to those markets. While many countries possess a fractionation capacity, the limiting factor in supply worldwide is the amount of plasma available, and nationalistic drivers for each country to have its own plant are inimical to product safety and supply. Rather, the provision of sufficient supplies of domestic plasma should be the focus of resource allocation, with a choice of an appropriate contract fractionator. However, contract fractionation too may be affected by domestic considerations unrelated to the needs of the country of plasma origin. This chapter will review the global plasma market and the influences on plasma and plasma product movement across national borders. Problems in ensuring adequate safety and supply will be identified, and some tentative approaches to the amelioration of current barriers to the provision of plasma derivatives will be outlined.

Blood Transfusion↗

Lifetime treatment costs of beta-thalassaemia major.

Beta-thalassaemia major is a serious genetic disorder, which results in a considerable increase in both acute and chronic morbidity, and mortality. Although beta-thalassaemia major is a rare disease affecting approximately 600 people in the UK, treatment is intensive and predictions of the costs incurred may aid health care planning. In this report, the cost to the health service of providing treatment services for beta-thalassaemia major patients, over the course of a lifetime, is calculated in order to assist resource allocation decisions. A cost model was developed, incorporating data from disparate sources. The undiscounted lifetime cost of treating a beta-thalassaemia major patient was estimated to be pound 803,002, although when the costs were discounted at a rate of 6%, the lifetime cost was reduced to pound 219,068. Within sensitivity analyses, the discounted cost ranged from approximately pound 188,000 to pound 226,000. This report may act as a guide to those involved in the planning of health care provision with regard to the resources required to treat beta-thalassaemia major patients. Such information may also be incorporated into the decision-making process for the provision of antenatal screening programmes for beta-thalassaemia major.

Adolescent↗

The usefulness of ratios for allocation decisions: the case of stroke.

Economic evaluation is becoming increasingly important in the field of stroke as well. The results of economic evaluation can be expressed in cost per quality-adjusted life years (QALY) gained, which enables policy makers to compare the relative efficiency of different interventions regarding different diseases. Although using the concept of QALY is preferable from a theoretical point of view, in medical practice more often cost-effectiveness analysis (CEA), and not cost-utility analysis, is applied for practical reasons. One of the main limitations of CEA is that the results may be compared only with results of other CEAs, using the same effect parameter. The calculation of cost-effectiveness ratios (CERs) in many cases is misleading for resource allocation. Effects should be expressed in interval or ratio scales in order to calculate CERs, which is rarely the case. The calculation of a CER in a CEA should only be performed if, and only if, the investigator is convinced that there is a constant relation between the specific effect parameter and the ultimate gain in health.

Cost-Benefit Analysis↗

Mass casualty management of a large-scale bioterrorist event: an epidemiological approach that shapes triage decisions.

The threat of a BT event has catalyzed serious reflection on the troublesome issues that come with event management and triage. Such reflection has had the effect of multiplying the efforts to find solutions to what could become a catastrophic public health disaster. Management options are becoming more robust, as are reliable detection devices and rapid access to stockpiled antibiotics and vaccines. There is much to be done, however, especially in the organizing, warehousing, and granting/exercising authority for resource allocations. The introduction of these new options should encourage one to believe that, in time, evolving standards of care will make it possible to rethink the currently unthinkable consequences. Unfortunately the cost of such preparedness is high and out of reach of most governments. Most of the developing world has neither the will nor the means to plan for BT events and remains overwhelmed with basic public health concerns (i.e., water, food, sanitation, shelter) that must take priority. Therefore, developed countries will be expected to respond using international exogenous resources to mitigate the effects of such a disaster. As a result, the state capacity of the effected government will be severely compromised. If triage and management of casualties is further compromised, terrorists will have met their goals. One could argue that health sciences will continue for decades to play catch up with the advanced technology driving potential bioagent weaponry. If one lesson was learned from the review of the former Soviet Union's biological weapons program, it is that the unthinkable remains an option to terrorists who have comparable expertise. It is crucial to develop realistic strategies for a BT event. Triage planning (the process of establishing criteria for health care prioritization) permits society to see cases in the context of diverse moral perspectives, limited resources, and compelling health care demands. This includes a competent and compassionate management and triage system and an in-depth and accurate health information system that appropriately addresses every level of threat or consequence. In a PICE stage I to III BT event resources will be compromised. Triage and management will be one process requiring multiple levels of cooperation, coordination, and decision-making. An immediate challenge to existing emergency medical services systems (EMSS) is the recognition that locally there will be a shift of emphasis and decision-making from prehospital first responders to community public health authorities. The author suggests that a working relationship, in most areas, between EMSS and the public health system is lacking. As priorities shift in a BT event to hospitals and public health care systems, they need to: 1. Improve their capabilities and capacities in surveillance, discovery, and in the consequences of different triage and management decisions and interventions in a BT environment, starting at the local level. 2. Develop triage and management systems (with clear lines of authority) based on public health and epidemiologic requirements, capability, and capacity (triage teams, categories, tags, rapid response, established operational priorities, resource-driven responsible management process), and link local level surveillance systems with those at the national or regional level. 3. Use a triage and management system that reflects the population (cohort) at risk, such as the epidemiologic based SEIRV triage framework. 4. Develop an organizational capacity that uses lateral decision-making skills, pre-hospital outpatient centers for triage-specific treatments, health information systems, and resource-driven hospital level pre-designated protocols appropriate for a surge of unprecedented proportions. Such standards of care, it is recommended, should be set at the local to federal levels and spelled out in existing incident-management system protocols.

Bioterrorism↗

The intensive care unit medical director as manager. Impact on performance.

This article examines the impact of greater management involvement by the medical director on efficiency of bed allocation in the intensive care unit (ICU) or critical care unit. Managerial involvement is modeled using a principal components approach in terms of perceived supervision, conflict resolution regarding bed allocation at critical times, extent of control over treatment, and employment status. Using data from a 1991 survey of 2,879 ICUs in 1,706 hospitals conducted by the Society of Critical Care Medicine, two equations reflecting efficiency--the ICU occupancy rate and the presence of misallocated ICU patients--were estimated. It was found that greater involvement by medical directors in the day-to-day management of the ICU significantly reduces the average occupancy rate in ICUs and also the probability of patients misallocated to the ICU, suggesting superior resource allocation in ICUs as a result. These results also suggest that the managerial impact of the medical director is greater in ICUs in high-occupancy hospitals.

Bed Occupancy↗

Resource intensity weighing and case mix grouping: assumptions and implications for health service performance evaluation.

The use of Resource Intensity Weights (RIWs*) for equity funding and utilization management assumes validity of the cost estimates, reliability of the patient categorization scheme, equivalence of the bases for cost comparison, and equity of the subsequent resource distribution. This paper examines these assumptions, and concludes that caution must be taken when using the current RIWs and Case Mix Groups (CMGs*) for resource allocation and performance evaluation purposes. RIW has represented a milestone in the history of Canadian health care product costing and management. It would be prudent for health care professionals at the operational level to provide structured and continuing feedback that can contribute to the validation and refinement of these valuable management tools.

Diagnosis-Related Groups↗

Creating project plans to focus product development.

The long-term competitiveness of most manufacturers depends on their product development capabilities. Yet few companies approach the development process systematically or strategically. They end up with an unruly collection of projects that do not match long-term business objectives and that consume far more development resources than are available. Instead of working on important projects, development engineers spend their time fighting fires. Their productivity sinks, and products are invariably late to market. To attack development malaise and reinvigorate the process, companies should put together an "aggregate project plan." The plan helps managers restructure the development process so they no longer think in terms of individual projects but in terms of the "set" of projects. It is the set, not individual projects, that shapes the creation of a successful product line. The aggregate project plan also helps managers allocate resources, sequence projects, and build critical development capabilities. A central element of the aggregate project plan is the project map. The map categorizes projects into five types: breakthrough, platform, derivative, research and development, and partnerships. Each project type has its own unique characteristics and requires a different amount of development time. Companies should have projects in all categories to ensure a robust development process.

Decision Making, Organizational↗

The analysis and assessment of health programs.

There is a vast gap between methodology and practice in the analysis and assessment of health programs. This presents an acute problem in developing countries where resource allocation decisions at the tight budgetary margin have important practical consequences. The prospects for improving this primitive situation depend critically on progress in analysis of the affordability and effectiveness of health programs. The analysis of affordability--especially on the recurrent cost side--is a necessary condition which can help ensure that proposed programs are unlikely to be vulnerable to implementation delays or underfinancing of operating costs which may seriously compromise the benefits expected from new investments. Improved analysis of effectiveness is also essential in order to help planners choose the best pattern of resource use from among the various combinations of programs that are affordable. To do this will require the devotion of substantial analytical effort to fill the great void of organized empirical knowledge available to those seeking to assess the effectiveness of health interventions. In particular there must be a shift in focus from single interventions directed at communicable diseases in children to a broader concern with multi-purpose interventions, including those directed against the emerging problems of non-communicable disease in adults.

Cost Control↗

Human resources for emergency obstetric care in northern Tanzania: distribution of quantity or quality?

BACKGROUND: Health care agencies report that the major limiting factor for implementing effective health policies and reforms worldwide is a lack of qualified human resources. Although many agencies have adopted policy development and clinical practice guidelines, the human resources necessary to carry out these policies towards actual reform are not yet in place. OBJECTIVES: The goal of this article is to evaluate the current status of human resources quality, availability and distribution in Northern Tanzania in order to provide emergency obstetric care services to specific districts in this area. The article also discusses the usefulness of distribution indicators for describing equity in the decision-making process. METHODS: We conducted a quantitative facility survey in six districts of Northern Tanzania. We collected data from all 129 facilities that provide delivery services in the study area. The data includes information on the emergency obstetric care indicators, as described by the WHO/UNICEF/UFPA guidelines for monitoring the provision of obstetric care. The inventory also includes information on the numbers of qualified health personnel at the basic and comprehensive emergency obstetric care level. We analysed the distribution and workload of the available human resources in a wider policy context with a particular focus on equity, use and quality, by means of descriptive statistics and the Spearman's correlation test. RESULTS: We determined that there are adequate human resources allocated for health care provision in Tanzania, according to national standards. Compared to similar countries however, Tanzania has a very low availability of health care staff. Most qualified staff are concentrated in a few centralized locations, while those remaining are inequitably and inefficiently distributed in rural areas and lower-level services. Rural districts have restricted access to government-run health care, because these facilities are understaffed. In fact, voluntary agency facilities in these districts have more staff than the government facilities. There is a statistical correlation between availability of qualified human resources and use of services, but the availability of qualified human resources does not automatically translate into higher availability of qualified emergency obstetric care services. CONCLUSION: National guidelines for human resources for health care in Tanzania require focused revisions in order to reflect the quality indicators more adequately when monitoring and setting criteria for HR distribution. Availability of qualified personnel as well as institutional management and capacity determine the quality of emergency obstetric care services and personnel. The current wide distribution of staff of inadequate quality should be reconsidered. The use of distribution indicators alone is not useful to properly monitor equity. This article suggests increasing access to high-quality health care instead of distributing low-quality services widely.

Journal Article↗

Program evaluation for effective resource management and accountability.

A means of determining the effectiveness of public programs as a basis for justifying resource allocation to these programs is urgently needed. Program evaluation can provide the data base required for program decision-making and modification. A ten-step model for planning and carrying out an evaluation is suggested as a guideline for program personnel who may be assigned to evaluation responsibilities. Nutrition professionals must become aware of the increasing need for evaluation and of the procedures for conducting the evaluation process within programs for which they are responsible. Failure to provide documentation of adequate, on-going evaluation of effectiveness may lead to a loss of resources for the program and, ultimately, to the demise of the nutritional care program.

Evaluation Studies as Topic↗

Effects of aerobic exercise and gender on visual and auditory P300, reaction time, and accuracy.

Visual and auditory reaction times (RTs) have been reported to decrease during moderate aerobic exercise, and this has been interpreted as reflecting an exercise-induced activation (EIA) of cognitive information processing. In the present study we examined changes in several independent measures of information processing (RT, accuracy, P300 latency and amplitude) during exercise, and their relationship to visual or auditory modalities and to gender. P300 latencies offer independent measures of cognitive speed that are unrelated to motor output, and P300 amplitudes have been used as measures of attentional allocation. Twenty-four healthy college students [mean (SD) age 20 (2) years] performed auditory and visual "oddball" tasks during resting baseline, aerobic exercise, and recovery periods. Consistent with previous studies, both visual and auditory RTs during exercise were significantly shortened compared to control and recovery periods (which did not differ from each other). We now report that, paralleling the RT changes, auditory and visual P300 latencies decreased during exercise, indicating the occurrence of faster cognitive information processing in both sensory modalities. However, both auditory and visual P300 amplitudes decreased during exercise, suggesting diminished attentional resource allocation. In addition, error rates increased during exercise. Taken together, these results suggest that the enhancement of cognitive information processing speed during moderate aerobic exercise, although operating across genders and sensory modalities, is not a global facilitation of cognition, but is accompanied by decreased attention and increased errors.

Adult↗

Ambulatory care nursing. A new approach.

This article describes one hospital's experience with integrating inpatient and outpatient nursing services. Nursing services integration enabled nursing management to combine the nursing resources allocated to the inpatient and outpatient components of a clinical service under the direction of one nurse manager. This new and creative approach was implemented in thirteen clinical services at the Victoria General Hospital, Halifax. This organizational structure was considered to be an effective approach for managing ambulatory care nursing services. The introduction of integration facilitated a change in the ambulatory care nursing role. It also provided for increased continuity of patient care and afforded nurses the opportunity to practice in another setting. Nursing services integration is considered a more effective approach for managing nursing resources.

Continuity of Patient Care↗

Can competition enhance efficiency in health care? Lessons from the reform of the U.K. national health service.

Since 1991 the reform of the U.K.-NHS has been introduced cumulatively. Public funding of health care has been retained and the goal of the reformers is to improve the efficiency of resource allocation by creating competition on the supply side of the market. The introduction of more autonomous Trust hospitals, general practice fund holders (GPFH) and the purchase-provider divide is described. The policy contradictions in the implementation of the reforms are analysed: the incomplete utilization of population weighted funding, the absence of a strategy in the development of GPFHs which are at once the mavericks and the catalysts of change in the new structures, the poor articulation of pricing and contracting rules, the maintenance of planned labour and capital markets which facilitate cost control but frustrate resource reallocation, and the incomplete articulation of many market rules (e.g. about merger and exit). It seems that the rhetoric of the market has been submerged in legislation and managerial rules which increase the power of central government rather than delegating control to local providers and purchasers. The lessons of the U.K. reforms for future innovators in the design of health care systems are numerous. Would a new Hippocratic Oath requiring the delivery by professionals of knowledge based medicine be as efficient but have lower transactions costs than the creation of an internal market? Who should regulate the health care market and how? How can reform best be sequenced? Is reform of funding (competing purchasers) an essential ingredient in the reform process or will supply side reform alone be adequate?(ABSTRACT TRUNCATED AT 250 WORDS)

Contract Services↗

Economic stress and mental health.

This paper correlates economic stress with minority status, resource allocations for mental health programs, and vulnerability to mental disability. Several hypotheses are advanced:1. A major and recurring psychological pattern of the American national character is prowhite, antiblack paranoia.2. Mental health fiscal allocations and programmatic determinations in ghetto, lower socioeconomic, minority-populated urban areas are predicated on political and racist considerations, the underlying motivation being to keep minorities at greater risk of mental disability.3. Economic privation and stress increase vulnerability to mental illness, especially in a minority population for whom health, mental health, educational, and social services are grossly inadequate.4. Poverty and economic stress combine with health systems that are unresponsive to the needs of blacks and other minorities, resulting in the perpetuation of disabilities and other conditions in blacks that are potentially preventable.5. Health and mental health resources should be increased rather than diminished during periods of economic stress, especially in the public sector.6. In order to provide each citizen with access to quality health and mental health care regardless of race and/or economic status, there must be enacted a national health insurance program based on tax-levy monies that will cover all aspects of health and mental health care.7. Racism and social status will continue to be powerful determinants of the quality of service that white professionals render to black patients and to poor white patients, unless our training institutions mount a massive campaign to train appropriately and to include significant numbers of minority candidates and trainees in the effort. To date this effort is virtually nonexistent.

Humans↗

A hospital service population model and its application.

The concepts of hospital service population and its estimation techniques is refined and generalized from a model-building point of view, and the generalized model is applied to the Alberta, Canada, hospital system. The assumptions underlying the so-called relevance and commitment index methods are investigated. A set of computer programs is developed for estimating the service population of Alberta hospitals. The programs use census, patient origin, and hospital statistics related to costs as input, and provide resource allocation and utilization rates on an age-sex adjusted per capita basis for all Alberta general acute hospitals and hospital districts. The estimates based on relevance and commitment index methods are compared and found to be very similar, except at the extreme tail areas of the distribution.

Alberta↗