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Pathogenesis of acute pelvic inflammatory disease: role of contraception and other risk factors.

In a case-control study of matched pairs, the risk of acute pelvic inflammatory disease (PID) was 4.4 times higher in intrauterine contraceptive device (IUD) users than in nonusers (p less than 0.001). Of approximately 500,000 cases of acute PID occurring annually in the United States, an estimated 110,000 are attributable to IUD's, costing over forty-four million dollars per year. PID was attributable to the IUD in 77 per cent of IUD users. No particular type of IUD was implicated. The relative risk of acute PID in IUD users over nonusers was higher in nulligravid women than in previously pregnant women and was directly related to socioeconomic status (SES), but the total annual risk of PID in IUD users appear inversely related to SES. IUD use significantly increased the risk of nongonococcal PID. Fever occurred in 13 (21 per cent) of 61 IUD users and 59 (41 per cent) of 143 nonusers (p less than 0.025). Among women with nongonococcal PID, and adnexal mass greater than or equal to 6 cm. was noted in 14 (40 per cent) of 35 IUD users and in only 12 (15 per cent) of 78 nonusers (p less than 0.01). An increased risk of gonococcal PID was found among non-Caucasians and women not using contraception, while the risk of nongonococcal PID was increased among women with a past history of gonorrhea. Oral contraceptive use may protect women with gonorrhea from developing PID. Menstruation precipitates the onset of symptoms of gonococcal PID.

Acute Disease↗

Pelvic inflammatory disease and contraceptive practice.

Analyses of data from the Women's Health Study suggest that the relative risks of hospitalization for PID were lower for women with tubal sterilizations and women whose partners had been sterilized (p less than 0.05), compared to sexually active non-contraceptors or women using oral or barrier methods. Further studies should be conducted to evaluate this non-contraceptive benefit of sterilization.

Adolescent↗

Contraceptive choice in Vigevano, Italy, 1983-1993.

The authors, after general consideration of family planning programs, present a study of 22714 women, who, in the decade 1983-1993, required contraceptive protection from the Family Planning Centers in the region of Vigevano (Italy). The authors underline the importance of a protocol used before beginning treatment to help prevent women receiving methods carrying too great a health risk. The results show a very high prevalence of oral contraception, increasing in recent years with the introduction of triphasic pills, while use of intrauterine contraception seems to be declining. Other conventional methods, such as barrier (diaphragm and condom) and 'natural' methods, had a low incidence in the sample studied. The reasons for these behaviors are analyzed and the relative trends discussed.

Adolescent↗

The information content of titles in contraception literature.

This paper attempts to evaluate the effectiveness of a keyword or descriptor in the title, from the viewpoint of document selection and information retrieval for scientists engaged in contraception research. A total of 2152 document titles recorded in the Index Medicus during 1973-75 was examined. Another set of 567 contraception titles published in the Index Medicus during 1963-65 was also studied to determine if there were any changes in the information content of the titles over a 10-year period. Employing the Montgomery-Swanson method, it was found that 92.2% of the documents from the later period and 88.0% of those from the earlier period had at least one "contraception term" in their titles. The data obtained in this study exceed those of published reports. A brief review of some of the previous studies dealing with the retrieval capabilities of titles in various branches of medical and life sciences is presented. It is concluded that the title search method is a very effective means of retrieving pertinent documents in the field of contraceptive technology. A trend of improvement in the information content of the scientific titles is also noted.

Contraception↗