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PubMed1974

Effect of sodium on the transport and utilization of citric acid by Aerobacter (Enterobacter) aerogenes.

Sodium inhibited citrate uptake by two of the four strains of Aerobacter (Enterobacter) aerogenes used in these studies, had no effect on one strain, and stimulated citrate uptake by one strain. Two of the four strains grew well anaerobically on citrate in the presence of Na(+), one grew poorly, and one grew not at all either in the presence or absence of Na(+). Na(+) stimulated the aerobic growth of one strain on citrate, increased the total growth but not the rate of growth of one strain, and prolonged the lag phase but not the rate of growth or total growth of two strains. The experimental data reported herein, therefore, indicate that there are appreciable physiological differences among strains of A. aerogenes.

Aerobiosis↗
PubMed1980

Studies on the formation of phosphoenolpyruvate and citric acid cycle intermediates by neonatal piglet liver mitochondria.

The capacity of mitochondria isolated from livers of 5-day-old piglets to convert pyruvate to phosphoenolpyruvate, malate and citrate has been investigated. These mitochondria have a large capacity to flux pyruvate through the pyruvate carboxylase reaction causing an accumulation of malate, citrate and phosphoenolpyruvate. As much as 70% of the pyruvate utilized during state 3 respiration can flux through the pyruvate carboxylase reaction. The data indicate that phosphoenolpyruvate from mitochondria can contribute a significant fraction of the carbon skeletons of pyruvate converted to glucose by piglet liver (estimated to be 30%).

Animals↗