[Homeostatic behavior and behavioral homeostasis].
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The three-hour immobilizational stress in two groups of males of rhesus monkeys at the age of 7-8 and 10-12 years has been investigated. The reaction on the stress has been established to depend on the age of animals. The young males bear the stress easier, their behaviour after it is practically normal. The normal behaviour of the elder animals restores during 24 hours after immobilization. A comparative analysis of hamadryas baboons and rhesus monkeys behaviour during this type of stress has been carried out. These species differ by their reaction on stress: Papio hamadryas serve as a model of hard depressive stress, the rhesus monkeys--a model of slight-stimulative stress. The peculiarities of stress bearing depend on the selected species, age of the animal, the type of social organization and individual features of behaviour.
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Using intraperitoneal injections, it was observed that kainic acid (KA) and its stereoisomer, allokainic acid (AKA), differ in their ability to produce wet-dog shakes (WDS), stereotypies and convulsions in Sprague-Dawley rats. KA induced this sequence of events for 5 hours after treatment while AKA had no effect even at much higher doses. On the other hand, both isomers induced sparring. KA caused also some significant changes in serotonin levels in hippocampus 6 days after injection while AKA did not. These findings suggest that WDS, stereotypies and convulsions depend on the position of the isopropenyl group in relation to the pyrrolidine ring of the molecule while sparring is not dependent on its spatial configuration.
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