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Results for “SLEEP DEPRIVATION”

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PubMed1984

Does paradoxical sleep deprivation disturb memory trace consolidation?

The effect of water tank PSD on memory in the passive avoidance test as well as on open field behavior was studied in rats. The effect of combining water tank PSD with a period of normal sleep-wakefulness cycle or with PSD by non-emotional awakening was investigated in a special series of experiments. It is concluded that PSD, even by the water tank procedure, does not disturb trace consolidation and formation of long-term memory in the passive avoidance test. However, a change in the correlation of motor-exploratory activity and fear reaction, due to the stressful situation intrinsic in the water tank PSD procedure, does not allow the animals to reach comparatively long temporal criteria in the passive avoidance test.

Animals↗
PubMed1981

Effect of sleep deprivation on tolerance of prolonged exercise.

Acute loss of sleep produces few apparent physiological effects at rest. Nevertheless, many anecdotes suggest that adequate sleep is essential for optimum endurance athletic performance. To investigate this question, heavy exercise performance after 36 h without sleep was compared with that after normal sleep in eight subjects. During prolonged treadmill walking at about 80% of the VO2 max, sleep loss reduced work time to exhaustion by an average of 11% (p = 0.05). This decrease occurred despite doubling monetary incentives for subjects during work after sleeplessness. Subjects appeared to fall into "resistant" and "susceptible" categories: four showed less than a 5% change in performance after sleep loss, while four others showed decrements in exercise tolerance ranging from 15 to 40%. During the walk, sleep loss resulted in significantly greater perceived exertion (p less than 0.05), even though exercise heart rate and metabolic rate (VO2 and VCO2) were unchanged. Minute ventilation was significantly elevated during exercise after sleep loss ( p less than 0.05). Sleep loss failed to alter the continuous slow rises in VE and heart rate that occurred as work was prolonged. These findings suggest that the psychological effects of acute sleep loss may contribute to decreased tolerance of prolonged heavy exercise.

Adult↗
PubMed2005

Sleep deprivation and psychosocial impact in acutely ill cancer patients.

Sleep is an important factor related to health and quality of life for all individuals. For people with cancer, sleep disturbances are common and are a source of distress. This article summarizes the problems and reviews the types, prevalence, etiology, risk factors, clinical sequelae, and management of sleep disturbances experienced by cancer patients. A comprehensive review of the literature is presented, along with direction for nursing practice and research.

Activities of Daily Living↗
PubMed2003

The night float paradigm to decrease sleep deprivation: good solution or a new problem?

In the late 1980s physician residency training programs developed the night float rotation, characterized by a sequence of 5 - 15 days of night work without any daytime duties, thereby involving an abrupt reversal of the wake - sleep schedule. We examined the effect of the night float rotation on sleep, mood and performance of pediatric residents. Residents completed sleep diaries daily, and tests of mood (Profile of Mood States) and attention (Conner's Continuous Performance Test) three times a week during the two-week night float rotation, and during equivalent blocks of time of their daytime rotations. Results show that, despite having ample opportunity to sleep during the day, while on night float rotation residents slept less than during the nights of their normal daytime rotations, 6.3 h +/- 2.5 h and 7.2 h +/- 1.7 h, respectively, p < 0.0001. Also, during night float compared to daytime rotations residents had increased fatigue-inertia scores, 8.7 +/- 4.1 and 4.8 +/- 2.4, respectively, p < 0.0001, and decreased vigor-activity scores 10.7 +/- 5.4 and 14.8 +/- 5.3, respectively, p = 0.02. The scores for attention were not significantly different between night float and daytime rotations. The correlation coefficients of fatigue with measures of attention were not statistically significant for daytime rotations. However, for night float fatigue correlated with omission errors, r = 0.51, p = 0.001 and with attentiveness r = - 0.36, p = 0.03. Training programs that adopt the night float rotation must be aware of potential deleterious effects of the night float rotation as they may lead to serious consequences on residents' performance and patients' safety.

Adaptation, Physiological↗
PubMed1985

Effects of rapid eye movement sleep deprivation on the feeding behavior in the laboratory rat with a description of the cuff pedestal technique.

The cuff pedestal technique, with which it is possible to use the test animal as its own control both before and after REMs deprivation, was described. The validity of this modified procedure for REMs deprivation was tested with reference to the electrophysiological sleep correlates using 6 adult rats deprived of REMs for 3 days. The stress effects of the cuff pedestal treatment were assessed in terms of adrenal weights in 12 rats. The duration of REMs deprivation in this experiment was 5 days. The effects of REMs deprivation on locomotor activity and food intake were studied in 8 juvenile rats exposed to REMs deprivation by lowering the cuffs for 6 days after 3 baseline days with the cuffs raised. 24 h recordings of meal pattern data were obtained from 8 adult rats during one baseline day, during the first and sixth day of REMs deprivation and during the second day after termination of REMs deprivation. The main results were as follows: The procedure of placing experimentally naive rats on small pedestals surrounded by water inhibited normal food intake for several days. Concomitant weight losses were of the same order as have been reported to occur in control rats on large pedestals. This finding suggests that both the large and small pedestals should be equipped with movable cuffs and that actual deprivation should be started by lowering the cuffs only when the animals have exceeded their original weights. The electrophysiological sleep/waking cycle of rats adapted to living on the pedestal with the cuff raised was similar to that reported in rats under ordinary laboratory conditions. Lowering of the cuffs for 3 days resulted in an almost total disappearance of REMs. A prominent rebound increase of REMs occurred after raising of the cuffs. Rats kept for fourteen days on pedestals with the cuffs raised displayed an increase of about 20% in the weights of the adrenal bodies. A quite similar adrenal hypertrophy, however, also occurs in rats living under enriched conditions. Lowering of the cuffs for the last 5 days did not induce any additional changes in the adrenal weights. These findings indicate that REMs deprivation achieved by means of the cuff pedestal does not induce any measurable physical stress. With the cuffs raised (no REMs deprivation), the rats displayed a prominent LD cycle of food intake characterized by very large meals consumed exclusively at the end of the dark period.(ABSTRACT TRUNCATED AT 400 WORDS)

Adaptation, Physiological↗