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[A case of metastatic rib tumor from thyroid cancer confirmed by the presence of thyroglobulin].

A 63-year-old female, with a chief complaint of right chest pain was referred to our hospital because of an abnormal right chest wall shadow on chest X-ray. A rib tumor was suspected based on her chest CT scan. Percutaneous needle biopsy yielded a diagnosis of well-differentiated adenocarcinoma. As metastatic rib tumor was suspected, the primary tumor was sought for. A thyroid gland nodule was recognized by ultrasonography, and the cytological diagnosis was class V. Immunohistological demonstration of the thyroglobulin studies of the rib tumor tissue revealed papillary and trabecular patterns of cell arrangement and the presence of thyroglobulin existence. Definitive diagnosis of metastatic rib tumor from thyroid cancer was established. Immunohistological examination is useful to confirm the diagnosis of metastatic cancer of thyroid origin.

Adenocarcinoma↗

Cultural study of diarrhoeal illnesses in central Thailand and its practical implications.

A cultural study of diarrhoeal illness was conducted using the Explanatory Model Interview for Cultural Assessment (EMIC) to compare two socioeconomically distinct subdistricts of central Thailand and to determine the practical implications of illness-related perceptions, beliefs and practices. Subjects specified 12 terms for diarrhoeal illnesses that were grouped into four locally meaningful groups, namely, tong-sia, a non-specific term for diarrhoea, bid, associated with colicky abdominal pain, ahiwa, referring to severe illness, often cholera; and taae-tua, diarrhoea associated with milestones of growth and development. To compare pre-existing beliefs and practices with the experience of caretakers when actually confronted with an episode of illness, we inquired about each of the terms and about index cases in subsequent interviews over the course of a six-month surveillance period. Patterns of distress, perceived causes, and preferences for help seeking and treatment elicited by the EMIC identified cultural features of the four groups of diarrhoeal illness. Perceived causes of diarrhoea associated with sanitation, hygiene and infection, which most respondents considered preventable, were prominent explanations for three of the four categories, and the fourth was viewed as a normal feature of growth and development, rather than medical illness. We discuss these and other findings with reference to use of ORS and other issues related to the prevention and control of diarrhoeal illness, concluding with recommendations for public health policy and research.

Child, Preschool↗

Towards less painful local anesthesia.

Local anesthesia, used for numerous procedures in all fields of medicine, has the drawback of providing significant pain upon injection. Twenty-eight volunteers were asked to compare a subcutaneous injection of plain lidocaine with an injection of lidocaine plus bicarbonate. Twenty-four of the twenty-eight volunteers reported less pain with the buffered lidocaine. The dilution of 1 part bicarbonate to 10 parts plain lidocaine produced a solution that was less painful and better tolerated. The local anesthetic lidocaine is used prior to many minor and major surgical procedures. Although it induces adequate anesthesia, the pain of injection is nearly always of considerable discomfort to the patient. There are numerous factors that have been shown to influence the pain of injection. These include speed of injection, size of needle used, area of the body injected, and simply individual patient characteristics. Since lidocaine comes as an acid solution, local tissue irritation is likely the primary source of pain.

Adult↗

Threshold of sensation for 60-Hz leakage current: results of a survey.

Canadian regulations have set a limit of 100 microA on leakage currents permitted to flow from patient-applied parts of an electromedical device under single-fault conditions, while international standards, such as International Electrotechnical Commission (IEC) 601-1, have set the limit of 500 microA under the same conditions. Canadian agencies have suggested that national standards for electromedical devices should harmonize with widely used international standards by increasing the leakage current limit to 500 microA. The authors investigated the question of whether 500 microA would compromise safety, or would be unpleasant or painful for the patient. A survey was conducted on the reactions of 95 adult volunteers to 60-Hz alternating currents ranging from 10 to 500 microA applied through typical ECG electrodes to determine the level at which these volunteers felt a distinctly uncomfortable or painful sensation. Results of this survey confirm that 500 microA currents are more than sufficient to induce pain in healthy adult volunteers, and that currents greater than 100 microA can evoke a definite sensation. Based on these findings, the authors recommend that the maximum allowable leakage current for patient-applied parts under single-fault conditions should not exceed 100 microA.

Adult↗

[A case report of sacral chordoma].

Sacrococcygeal chordoma is one of the retrorectal tumors. Relative rarity and anatomical location of this may lead to difficulty in diagnosis and surgical treatment. We report a case of sacrococcygeal chordoma successfully treated by high sacral resection by a posterior approach, in which the co-operative efforts of gastroenterological surgeons and an orthopedic surgeon were employed. A 64-year-old man with a long term continued vague anal pain was referred to our hospital. Digital rectal examination revealed an elastic hard mass presacrally. Plain sagittal radiograph, CT, barium enema showed a retrorectal mass and sacral destruction. Diagnosis was confirmed histologically by the specimen taken by open biopsy. Surgical resection was carried out in prone position with the buttocks elevated. The skin incision was upward arched transverse. The lower sacral vertebrae, including S3, were removed en block with the tumor. Bilateral S3 sacral nerve roots were preserved. Postoperative disturbances of the urination and defecation were not seen. High dose radiation therapy, 80 Gray, was done after surgery. Radiation ulcer of the skin was treated by free skin graft, but radiation proctocolitis was not seen. Now he is free from the disease.

Biopsy↗

Fibrositis: symptom frequency and criteria for diagnosis. An evaluation of 291 rheumatic disease patients and 58 normal individuals.

We administered a 17-item symptom questionnaire modified from Campbell to 155 patients with fibrositis diagnosed at 3 centers, each using different criteria sets. A high degree of agreement in symptom proportions was found among centers. "Fibrositic" symptoms were also common in 136 patients with a variety of rheumatic diseases but not in the 58 normal individuals studied. Symptoms distinguished fibrositis patients from normals easily, but had insufficient specificity to distinguish them from other rheumatic disease patients. The tender point count better separated fibrositic and nonfibrositic patients than historical criteria. No combination of questions and tender point count performed better than the tender point count alone.

Back Pain↗

Crouzon syndrome. A review of literature and case report.

A sporadic case of Crouzon Syndrome without mental retardation is described. The patient, an 11 year old boy with grossly carious teeth and in severe pain was referred for dental treatment. A review of literature on Crouzon Syndrome is presented.

Anodontia↗

The painful shoulder: MR imaging of the glenohumeral joint.

We used magnetic resonance imaging in 41 patients with shoulder pain. Magnetic resonance was found useful in depicting the spectrum of rotator cuff abnormalities associated with mechanical impingement including both large and small rotator cuff tears as well as tendinitis. Abnormalities of the capsular mechanism, osseous tumors, osteonecrosis, and injuries to the supporting musculature are also well depicted.

Adolescent↗

[Deontological problems of childhood and adolescence].

Due account of age-related features of infantile and juvenile psychology and psychopathology is considered to be a major principle in general medical deontology as related to personality psychology and psychiatry in children and adolescents. Three main types of personality formation in childhood and character accentuation in adolescence are defined. Deontological practice attributes an important value to defining the "type of emotional experience of disease" and peculiarities of "adaptive responses to disease". The term "type of emotional experience of disease" signifies the character of personal response of a child realizing he or she is sick. Anosognostic, dysthymic and regressive types of experiencing a disease are most common for children. In adolescence, hysteroid, depressive-phobic, anxious-depressive and depressive-hypochondriac types were also found. The psychological and pathological forms of "adaptive response to disease" in children and adolescents are described. The problem of prevention of the negative impact of several factors linked with the patients hospitalization is discussed with special reference to painful diagnostic and therapeutic manipulations, psychic deprivation, hospitalism as well as iatrogenesis, egrotogenia and didactogenia. The psychotherapeutic and psychocorrective policy is considered as being aimed at preventing the negative effect of therapeutic-diagnostic work on the child or adolescent psychic sphere.

Adaptation, Psychological↗

Pain sensitivity in obesity.

Pain sensitivity of the obese and control women was investigated using an electrophysiological method. The sensory and pain threshold were higher in the obese than in the control subjects. Pain sensitivity of the control as well as that of the obese women increased significantly during the day from morning to evening. The circadian rhythm of the sensory and pain thresholds with peak values (acrophase) in the morning was significant only in control women. Weight reducing treatment did not change the pain sensitivity in obese women.

Adult↗

[A case of retroperitoneal chylous cyst developed after cholecystectomy and choledochotomy].

A 43-year-old woman complaining of upper abdominal pain was referred to our clinic. Well movable mass was detected in the right hypochondria region by palpation. Three years before, she underwent cholecystectomy and choledochotomy for cholelithiasis. After that she had been aware of painless mass in the right hypochondria region, but because of no symptom she regarded it as operative scar and had no treatment. Abdominal CT, ultrasonography, upper GI series and barium enema revealed a retroperitoneal cyst compressing the 3rd portion of the duodenum upward and the vena cava backward. Laparotomy showed an unilocular chylous cyst, 5 cm in diameter in the retroperitoneal cavity. Histologically, the cyst was cystic lymphangioma. Etiologically, the previous operation of cholecystocholedocholithiasis was supposed to be a trigger of the development of the chylous cyst.

Adult↗

Basal gastric acid secretion in children with atypical epigastric pain.

We investigated basal acid output (BAO) by nasogastric aspiration in 28 children with atypical recurrent abdominal pain, defined as subxyphoid or epigastric pain of more than 3 months duration, associated with vomiting, anorexia, failure to thrive, and/or nocturnal awakening. Twenty-one children had normal upper endoscopies with no esophageal mucosal disease on biopsy, and seven had acid-peptic mucosal disease seen either on endoscopy or on esophageal biopsy. Mean BAO in the children with acid-peptic mucosal disease (6.8 +/- 4.3 mEq/h) was significantly higher than the mean BAO in the children with no mucosal disease (2.4 +/- 1.7 mEq/h) (p less than 0.02). Gastric volumes were also significantly greater in the children with acid-peptic mucosal disease than in children with no mucosal disease (p less than 0.001). There was no significant correlation between body weight and either BAO or basal volume output. Three of seven children with acid-peptic mucosal disease had a BAO greater than two standard deviations above the mean for the group with no mucosal disease. Two of these three had a BAO of more than 10.0 mEq/h (defined as gastric acid hypersecretion in adults), and required higher than usual doses of H2 blocker therapy. These results indicate that the values for BAO in children (greater than 2 yr) are comparable to values recorded in adults. Moreover, measurement of BAO may define a subgroup of children with atypical abdominal pain who are hypersecretors of acid and who require higher doses of antisecretory agents in order to achieve an optimal clinical response.

Abdomen↗

Cluster headache after orbital exenteration.

A 56-year-old woman developed episodes of throbbing pain in the right orbit accompanied by ipsilateral nasal stuffiness and the feeling of ear swelling six months after orbital exenteration and ethmoidectomy for invasive, sclerosing basal-cell carcinoma. Extensive evaluation and treatment of her sinusitis failed to provide relief for her disabling symptoms. When treated by a neurologist with propranolol for cluster headaches, her symptoms subsided. To the best of our knowledge, this is the second patient with cluster headaches after orbital exenteration. Though no known causal relationship exists, these two patients document that orbital or ocular pain with cluster headaches is a referred or "phantom" pain and confirm the etiology of cluster headaches to lie outside the orbit.

Basal Cell Carcinoma↗

[Emphysematous pyelonephritis: report of a case].

A case of emphysematous pyelonephritis is presented. A 49-year-old male with diabetes mellitus complaining of high grade fever attack and right flank pain was referred from internal medicine. KUB demonstrated that the right ureter, pelvis and calyces were filled with gas. Anti-bioticus was given intensively and the abnormal gas shadow on plain film disappeared before RP was done, but high grade fever attack persisted and right nephrectomy was undergone. After this operation, the fever was relieved and the patient was discharged at the 30th day post-operatively. A search of available literature in Japan has disclosed only 17 reported cases. Diagnostic methods, treatment, complication and etiology are discussed.

Diabetes Complications↗

Chondroblastoma. A review of seventy cases.

We reviewed the cases of seventy patients with chondroblastoma who were treated at the Istituto Ortopedico Rizzoli between 1949 and 1983 and found that the proximal end of the humerus was the most common location (eighteen), with the proximal end of the femur (fifteen), distal end of the femur (fifteen), and proximal end of the tibia (twelve) being the other frequently involved sites. Sixty-three of the patients were between eleven and thirty years old. Fifty-eight patients sought medical attention because of an aching pain, usually referred to the adjacent joint. Fifty patients were followed for two years or longer after treatment. Seven patients had a local recurrence: four were successfully treated with a repeat curettage and one, by two subsequent marginal excisions; one was advised to have a repeat curettage; and the seventh was advised to have a resection and arthrodesis of the knee. The final functional results were considered to be excellent in forty-seven of the fifty patients who were followed for two years or more.

Adolescent↗