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[Effect of vibration and noise on glycosaminoglycan (mucopolysaccharide) and hydroxyproline excretion].

In 126 humans occupationally exposed to local vibration and in 50 humans exposed to general vibration, glycosaminoglycanuria (GAG) and hydroxyprolinuria (HP) were examined. In addition, all subjects were exposed to industrial noise. An increased GAG excretion in those exposed to the vibration of low and medium frequencies was found, which is indicative of a damage to the basic substance of the connective tissue. The exposure to the lowest frequencies increases the HP excretion, thus indicating a damage to the collagen fibers.

Adult↗

[Evaluation of hydroxyproline excretion in the urine (UHP) in prostate carcinoma].

82% of the male patients with healthy urogenital tract showed an isoelectric line in the stimulataneous EMG-derivation of the sphincter of the bladder under conditions of rest; in 18% of the males a moderate activity was present. In voluntary innervation at once an intensive electric activity of a spinle-shaped discontinuous pattern of the action potential developed in 76% of the patients. In the pressing trial in 83% of the cases a slight to moderately strong activity appeared. In contrast to the examined patients with healthy outlet of the vesicle the patients in whom an adenoma of the prostate gland or a carcinoma of the prostate gland, respectively, was present exhibited deviations from the normal pattern of the action potential, in which cases carriers of adenoma and carcinoma differed. Whether and to what extent the electromyography on the m. sphincter vesicae allows the possibility of the differentiation between adenoma of the prostate gland and carcinomaof the prostate gland in the early clinical stage shall be reserved for further examination.

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