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At least 1,459 records · Page 81Linked to original sources
PubMed1995

Responses of type I and type III collagen synthesis after replacement of the hip joint.

Liberation of the carboxy-terminal propeptide of type I procollagen (PICP) and the amino-terminal propeptide of type III procollagen (PIIINP) into body fluids reflects synthesis of the respective collagen types. Here, we followed PICP and PIIINP in serum with specific radioimmunoassays after hip surgery. Preoperative median of S-PICP was 112 micrograms/liter (range 87 to 154, n = 9), the 1-day median being 58 micrograms/liter (33 to 79). The corresponding medians for S-PIIINP were 4.4 micrograms/liter (3.5 to 7.0) and 3.3 micrograms/liter (2.0 to 3.5). The medians reached their maximums 14 days after surgery, 172 micrograms/liter (122 to 440) for S-PICP and 12.4 micrograms/liter (8.0 to 15.4) for S-PIIINP, after which the preoperative values were slowly approached over several months. Comparable results were found in a greater sample (n = 50). Our results indicate that the synthesis of structural collagen is inhibited immediately after surgery, but the inhibition is soon overcome by active collagen synthesis at the site of trauma. Collagen metabolism remains activated for several months after surgery.

Collagen↗
PubMed1993

Research and development of alumina and zirconia artificial hip joint.

The object of the experiments was to discover the static and dynamic load-carrying capacity of a prosthetic system consisting of a titanium allow stem, zirconia ceramic ball head and UHMWPE (ultra-high molecular weight polyethylene) socket molded in the ceramic shell, the latter two were both of 22 mm in diameter. The components of the artificial hip joint were placed in a vertical position and load was applied, alternating between 0 and 10 kN and then 12 kN with a frequency of 30 Hz under Ringer's solution up to 10 7 cycles respectively. After 2 x 10 7 cycles there was no sign of damage to be observed among the system tested using the joint simulator. This seems to be a very high safety factor compared with loads occurring in vivo.

Evaluation Studies as Topic↗
PubMedDate not supplied

[Experience with 466 re-examined Wagner double-cup hip joint endoprostheses].

Between 1976 and 1981 a total of 558 Wagner Cup prostheses were implanted. This paper reports on 7 years of experience with this prosthesis, with a failure rate of 12.4%. The causes of failure are attributable to exaggerated indication and the design of the prosthesis. In the authors' opinion, the original-model Wagner cup prosthesis should no longer be used.

Follow-Up Studies↗
PubMedDate not supplied

[Hip joint changes in meningomyelocele].

With an incidence of approx. 2% among newborns, meningomyelocele is a rarely encountered condition. Its clinical manifestations vary within very wide limits, ranging from minor disability to extremely severe limitation of physical function. The function of the trunk muscles and of the lower extremities, and especially that of the hip joints, is impaired to different degrees in the patients affected, depending on the severity of the paralysis. The changes associated with meningomyelocele are typical, and the therapeutic principles adopted will usually depend on individual findings. Taking the disability into account, the primary goal must be to achieve optimal function. The value of imaging procedures is secondary to this consideration. In recent years a number of conventional therapeutic principles have undergone substantial modifications.

Child↗
PubMed1994

Cartilage stresses in the human hip joint.

The total surface stress measured in vitro on acetabular cartilage when step-loaded by an instrumented hemiprosthesis are partitioned into fluid and cartilage network stresses using a finite element model of the cartilage layer and measurements of the layer consolidation. The finite element model is based on in situ measurements of cartilage geometry and constitutive properties. Unique instrumentation was employed to collect the geometry and constitutive properties and pressure and consolidation data. When loaded, cartilage consolidates and exudes its interstitial fluid through and from its solid network into the inter-articular gap. The finite element solutions include the spatial distributions of fluid and network stresses, the normal flow velocities into the gap, and the contact network stresses at the cartilage surface, all versus time. Even after long-duration application of physiological-level force, fluid pressure supports 90 percent of the load with the cartilage network stresses remaining well below the drained modulus of cartilage. The results support the "weeping" mechanism of joint lubrication proposed by McCutchen.

Anthropometry↗