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Women and HIV disease: an emerging social crisis.

Women are the fastest growing category of people with AIDS in the United States, yet this fact has been consistently ignored in the social work literature. Social workers' expertise is needed to curtail the escalating social crisis of women with HIV disease. This article addresses the major social issues faced by women with HIV disease and explores gender differences in HIV transmission, disease progression, and diagnosis. The author discusses the ways in which women's sexuality and reproductive rights are affected. Specific issues are examined regarding HIV-infected women who use intravenous drugs, women of color, prostitutes, and lesbian and bisexual women. The implications for the social work profession are discussed, and social workers in the AIDS arena and all concerned about HIV-infected women are urged to address this problem on an individual as well as a community level.

Female↗

Gender and its effect in cardiovascular pharmacotherapeutics: recent considerations.

Gender differences in drug pharmacokinetics and pharmacodynamics have been recognized for some time. This issue has generally been ignored in clinical practice, despite there being ample evidence to suggest that gender can influence multiple aspects of pharmacokinetics. Gastric acid secretion, gastrointestinal blood flow, proportions of muscular and adipose tissue, the amount of drug-binding proteins, gender-specific changes in the available amount of P450 isozymes, physiologic and hormonal changes during the menstrual cycle, and differences in renal blood flow are several factors that may have some bearing on sex-related differences in pharmacokinetics. Furthermore, female-specific issues such as pregnancy, menopause, oral contraceptive use, and menstruation may independently influence drug metabolism and serve as confounders to the interpretation of gender differences in drug handling or effect. While gender-related pharmacodynamic data are limited, evidence suggests that women are more prone to the development of torsade de pointes from proarrhythmic drugs such as quinidine or d-sotalol and have an increased cardiovascular risk with the use of digoxin. The specific risk:benefit ratio for individual cardiovascular medications should be more routinely considered in the context of gender.

Cardiotonic Agents↗

Staff attitudes towards the care of the critically ill in the medical intensive care unit.

In an attempt to study the basis for conflict and tension surrounding decision making in ICU settings, a questionnaire was used to examine staff attitudes in a newly opened medical ICU in four major areas: (1) ethical issues; (2) decision-making process; (3) communications; and (4) emotional reactions of staff. All of the 36 house officers and 32 of 34 nurses (all RNs) completed the questionnaire. Results showed there was no monolithic nursing as opposed to physician position on any issue. Futhermore, professional role exerted a more profound influence on attitudes than gender or religious background. There was remarkable agreement between physician and nurse groups on ethical issues. However, nurses were less satisfied with the decision-making process and communication in the medical ICU and were more aware than physicians of their own and other's emotional reactions. The results suggested four ways to reduce tension in the medical ICU: (1) frankly recognize the inevitability of conflict and tension in a system where physicians have ultimate authority; (2) avoid perpetuating stereotypes; (3) maximize the continuity of physician care; and (4) maximize communication between and within professional groups.

Attitude of Health Personnel↗

Access to quality: evaluation of the allocation of deceased donor kidneys for transplantation.

Disparities in both access to the kidney transplant waiting list and waiting times for transplant candidates have been extensively documented with regard to ethnicity, gender, socioeconomic factors, and region. However, the issue of access to equivalent quality organs has garnered less attention. The principal aim of this study was to determine whether certain patient populations were more likely to receive lower quality organs. This was a retrospective cohort study of all deceased-donor adult renal transplant recipients in the United States from 1996 to 2002 (n = 45,832). Using previously reported categorization of donor quality (I to V), the propensity of transplant recipients to receive lower-quality kidneys in a cumulative logit model was evaluated. Older patients were progressively more likely to receive lower-quality organs (age > or = 65 yr, odds ratio [OR] = 2.1, P < 0.01) relative to recipients aged 18 to 24 yr. African American and Asian recipients had a greater likelihood of receiving lower-quality organs relative to non-Hispanic Caucasians. Regional allocation networks were highly variable with regard to donor quality. Neither recipient gender (OR = 1.00, P = 0.81) nor patient's primary diagnosis were associated with donor quality. Findings suggest that disparities in the quality of deceased donor kidneys to transplant recipients exist among certain patient groups that have previously documented access barriers. The extent to which these disparities are in line with broad policies of equity and potentially modifiable will have to be examined in the context of allocation policy.

Adult↗

Determinants of operative mortality in valvular heart surgery.

OBJECTIVE: In some respects, outcome reporting in valvular surgery has been hampered by focusing on specific populations, reluctance to publish high-risk subgroups, and possibly skewed or inadequate samples. The goal of this study was to evaluate risk factors for operative mortality comprehensively across the entire spectrum of cardiac valvular procedures over the past decade. METHODS: All 409,904 valve procedures in the Society of Thoracic Surgeons database performed between 1994 and 2003 were assessed, and Society of Thoracic Surgeons preoperative and operative variables were related to operative mortality by using a multivariable logistic regression model. Data were greater than 95% complete, and the relative importance of relevant risk factors was determined by ranking odds ratios. The analysis had a high predictive power, with a C statistic of 0.735. RESULTS: In the model, 19 variables independently influenced operative mortality (all P < .01). The most significant was nonelective (acute) presentation (odds ratios, 2.11), followed by advanced age (odds ratios, 1.88), reoperation (odds ratios, 1.61), endocarditis (odds ratios, 1.59), and coronary disease (odds ratios, 1.58). Generally, valve replacement was associated with higher mortality than repair (odds ratios, 1.52). Overall, female gender was very important (odds ratios, 1.37), and earlier year of operation increased risk (odds ratios, 1.34), implying improving outcomes over time. Although any single comorbidity, on average, was only moderately contributory (odds ratios, 1.19), specific comorbidities, such as renal failure, or multiple comorbidities in a given patient could be very significant. Aortic root reconstruction carried the highest risk (odds ratios, 2.78), followed by tricuspid valve surgery (odds ratios, 2.26), multiple valve procedures (odds ratios, 2.06), and then isolated mitral (odds ratios, 1.47), pulmonic (odds ratios, 1.29), and aortic (reference procedure) operations. Reduced ejection fraction and severity of valve lesion were relatively less important (odds ratios, 1.34 and 0.83, respectively). CONCLUSIONS: These data illustrate the significance of acute presentation in determining operative risk, and earlier surgical intervention under elective conditions might be emphasized for all types of significant valve lesions. Because aortic root reconstruction doubles mortality compared with simple aortic valve procedures, root replacement should be reserved for specific root pathology. Finally, issues related to reoperation, endocarditis, valve repair, gender, and the various procedures deserve more detailed examination.

Aged↗

Women's oral health issues: an exploration of the literature.

As interest in women's health issues grows, there is increasing concern that today's practice of medicine may not meet the health needs of women. A primary reason is the gender bias that has been inherent in medical education, research and clinical practice. The prevailing medical viewpoint has often been that the male body is considered to be the norm and that the female body exactly the same except for the reproductive function. This attitude has led to a lack of interest in researching gender differences and a consequent lack of knowledge of women's health issues. Fortunately, there is a movement for change. The Women's Health Interschool Curriculum Committee was formed in January 1992 to develop curricula concerning women's health and examine bias that may exist in existing curricula. The Canadian Women's Health Network has been growing across the country and there have been calls to create a new specialty in women's health. According to Angell, this proposal for a new specialty was provocatively debated in the Journal of Women's Health, which started publication in 1992. There is also a growing concern on how to conduct better research to address women's health needs. As more attention is paid to women's health issues, what will happen in the area of oral health? In health care, it would seem that the mouth has become completely separated from the rest of the body. Health conferences rarely have any oral health content at all. To correct this problem, there must be an increase in general awareness of the importance of oral health as it relates to the overall health of both women and men. Good oral health is more than just decay-free teeth. Oral health encompasses the teeth, the supporting periodontal structures, soft tissues of the mouth and oral pharynx area, temporomandibular joints and muscles of mastication. The mouth is a gateway to the body and will also reflect many systemic health problems, such as diabetes, leukemia and lupus. The second step would be the recognition that women may have different oral health needs and issues than men. The common view may be that teeth are gender free, but how can this be when teeth exist in a body, and that body is male or female? For many years, the primary acknowledged difference between men and women's oral health was pregnancy gingivitis. Like medicine, dentistry must re-examine the viewpoint that women's oral health differs from men's only as it is influenced by reproductive processes. There are many areas where women's oral health may differ from that of men. This paper will explore the literature for potential women's oral health issues in the areas of oral hygiene behaviours, esthetics, eating disorders, temporomandibular disorders, and hormonal influences on periodontal health.

Aging↗

Hypertension in women: current understanding of gender differences.

High blood pressure is a major individual and public-health issue because of its wide prevalence and associated complications. More women than men have hypertension, but until recently, women have been relatively underrepresented in clinical trials. Gender differences in the physiology, genetics, and treatment benefit of hypertension have been noted in several studies that have included women. These findings have raised concerns about the generalizability of the results of previous investigations to women. The currently available information regarding gender differences and similarities and the results of hypertension treatment trials in women are reviewed herein. These studies suggest that, although gender differences exist, women benefit significantly when they receive therapy to normalize blood pressure.

Estrogen Replacement Therapy↗

New directions for the study of overweight.

In this issue, three authors contribute to our knowledge of triggers or cues to weight-related behavior. Two of these authors focus on the effect of emotion on eating behavior. Popkess-Vawter, Wendel, Schmoll, and O'Connell (1998, in this issue) explicate reversal theory as a way to account for feelings and stress that trigger weight cyclers to overeat. Timmerman (1998, in this issue), in a study of nonpurge binge eaters, reports the relationship between caloric intake patterns and binge eating. Both researchers have added to our knowledge about triggers to eating behavior. Finally, Brink and Ferguson (1998), in their study of male and female successful dieters, add to the limited knowledge concerning triggers to weight loss. They describe reasons for deciding to lose weight among a population of successful underweight, normal weight, and obese dieters. Three authors contribute to the new weight research thrust of prevention. Two of the authors report the results of intervention studies. Reifsnider (1998, in this issue), in the only article on children, presents a follow-up study of a family-focused, community-based nursing intervention for growth-deficient, low-income Euro-American and Mexican American preschool children. Her work is an example of the context- and lifestyle-sensitive prevention-focused studies needed in weight research. Ciliska (1998, in this issue) reports findings from a randomized trial of a psycho-educational intervention with obese healthy women aimed at increasing self-esteem and decreasing restrained eating patterns. Her work follows some new thinking in the area of weight control that recognizes the dangers of chronic dieting and proposes a focus on self-acceptance, better nutrition, regular physical activity, and the prevention of further weight gain triggered by chronic dieting (Brownell & Cohen, 1995). Walker (1998, in this issue), the third author, in a multiethnic study of new mothers, explores the concept of weight-related distress and associations of anthropometric and psychosocial variables with feelings about weight. Her work adds to our understanding about critical periods and risks for weight gain. Allan (1998, in this issue), in a study of African American, Euro-American, and Mexican American women, reports women's explanatory models of overweight and the congruence of these models with professional models and recommendations for treatment for overweight. Her research contributes needed understandings of how high-risk populations view overweight, how participants' lifestyles and situations influence their ideas about weight, and how these perspectives influence efforts to control weight. Nursing needs to continue to refine and rethink what constitutes research on weight. This special issue offers some examples of scholars attempting to trailblaze new directions in nursing weight research. One thrust has been the significant attention on weight as a focus of investigation and not just as one of several health behaviors. A second and equally compelling area of inquiry has been the explicit attention directed to studying people of color, especially women, within the social context of their lives. Because ethnicity, social status, and gender are inextricably intertwined with health, one challenge is to try to understand weight issues through an ethnic, gender, and social status lens. Researchers who embrace this paradigm refuse to look at weight as a homogeneous condition but focus their attention instead on specific subgroups in the population without making middle-class Euro-Americans the norm. The number of researchers who are examining connections between ethnicity and social status and weight is growing. The complexity of weight-health promotion requires that we not only boldly examine weight in relationship to the individual in context but also explicate the macroenvironmental influences on weight. More needs to be done to translate findings from this body of research into better models

Adolescent↗

The impact of cultural context on Brazilian adolescents' sexual practices.

AIDS prevention research has demonstrated that theoretically driven HIV prevention programs can be tailored to specific cultures. Further, condom self-efficacy and contraceptive self-efficacy scales have been tested in the U.S. and been shown to predict condom and contraceptive use. Results of condom and contraceptive self-efficacy studies have been used to suggest ways to educate and counsel young people to avoid unprotected sex. This paper reports the findings from our research in Salvador, Brazil, using Levinson's Condom Self-Efficacy Scale (CDSE). The data are derived from six focus groups totaling 76 teenagers from three high schools. The focus group discussions explored cultural and psychological issues involved in condom use. Here we report on the gender dynamics of condom use as revealed by these urban Brazilian teenagers. Three focal points for behavioral change are identified: (1) issues of masculinity, (2) issues of femininity, and (3) condom use skills.

Adolescent↗

The aging gender dysphoria (transsexual) patient.

Ten aging gender dysphoria patients (eight men and two women, average age 52 years) were the subjects of this study. All had presented to the Gender Identity Clinic at Case Western Reserve University requesting sex-reassignment surgery. A psychiatric-psychological profile of the patients, their sexual functioning, problems with aging, diagnostic issues, and follow-up are discussed. The aging gender dysphoric patient presents in acute crisis, that is, exhibiting marked depression, increased suicidal ideation and behavior, and urgent perception of time. Diagnostic and treatment recommendations for aging gender dysphoria patients and their depressions are provided. Furthermore, guidelines are suggested for differentiating the aging transvestite with transsexual symptoms and the aging transsexual for whom sex-reassignment surgery may be indicated. Specific treatment strategies for an aging population, including sexual surgery, are also discussed.

Aging↗

Physician gender bias in clinical decisionmaking: screening for cancer in primary care.

There has been increasing interest in gender disparities in clinical decisionmaking. Few studies have examined this issue in nationally representative samples or focussed on primary care. In addition, few of the studies have examined the role of physician gender. The 1987 National Medical Expenditure Survey was used to examine the relationship between physician gender and screening deficiency in women for three gender-sensitive tests (breast examinations, Papanicolaou tests, and mammograms) and one gender-neutral test (blood pressure checks). Women reporting a female physician as their usual provider compared with those reporting a male physician were less likely to be deficient for Papanicolaou tests and mammograms. There was a smaller, but nonsignificant similar trend for breast examinations. No gender bias was evident for blood pressure checks. These results persisted after multivariate adjustment for patient age, race, education, income, insurance status, subjective health status, other health behaviors, and attitude toward health care and health insurance. The results confirm the existence of physician gender bias in clinical decision making and represent one area for quality improvement.

Adult↗

[Gender focus and the relationship between health and work in the context of productive reorganization and underemployment].

This article analyzes the issue of workers' health in the context of productive reorganization, based on the sexual division of labor and gender relations. The author begins with a discussion of cross-cutting issues and moves on to analyze current trends: the increase in female labor, its incorporation by multinational companies in the so-called Third World countries, an increase in differences and greater vulnerability vis-à-vis the process involving underemployment and suspension of social labor clauses. Finally, two examples of female labor (in industry and the school system) foster reflection on the effect of productive reorganization on working women's health, highlighting the issue of excessive workloads for women.

Developing Countries↗

Gender and social differences in adolescent sexuality and reproduction in Nicaragua.

PURPOSE: The aim of this research was to study gender and social differences in adolescent sexuality and reproduction, as reflected in age at first intercourse and age at first pregnancy, as a basis for future interventions in the municipality of León, Nicaragua. METHODS: In a community-based cross-sectional study including 7789 households, all women aged 15-49 years (n = 10,867) were interviewed about socioeconomic, sexual, and reproductive issues. A random subsample of men (n = 388) and women (n = 413) aged 15-49 years was interviewed in more detail about sexual patterns and reproduction. RESULTS: The median age at first intercourse for women and men was 17.8 and 16.2 years, respectively. Women's average latency period to end of first pregnancy was 22 months. There was a significant tendency to start active sexual life later among today's girls aged 15-20 years, compared to the groups 21-27, 28-35, and 36-49 years old. A similar trend was found in age at first pregnancy. These secular trends were not found among men. Age at first pregnancy for current adolescents was lower among those having less formal education. CONCLUSIONS: The short latency period between first sexual intercourse and end of first pregnancy, probably reflecting lack of access to counseling and contraception, is worrying in light of the growing sexually transmitted disease/human immunodeficiency virus threat. The secular trend of later start of reproduction, however, is a positive sign which partly may be an effect of increasing education in the Nicaraguan society.

Adolescent↗

Tools for integrating women's health into medical education: clinical cases and concept mapping.

The authors describe two teaching tools, case-based learning and concept mapping, and how they support cross-disciplinary, multidisciplinary, and interdisciplinary learning, use a biopsychosocial model, and promote the integration of sex- and gender-based science into the medical curriculum. The process of case development at MCP Hahnemann University (MCPHU) is outlined in detail for a specific case. That case, which integrates three different components of women's health, is then presented in full. The authors then provide an example of a concept map dealing with women and alcohol use; the map defines current knowledge and serves as a blueprint for developing curricular goals and learning objectives for the topic. Properly constructed concept maps and cases help teach patient-centered approaches to problem solving, address sex- and gender-based differences in disease as well as in pathophysiology and pharmacology, integrate psychosocial issues-such as family dynamics, environmental stressors, access to health care, effective gender-based communication between patient and provider, and cultural variations-along with biomedical ones, and encourage a multidisciplinary approach to patient care. The authors maintain that these tools might be used to transform medical education by making it more integrated and interdisciplinary.

Alcohol Drinking↗

Effect of grammatical gender on visual word recognition: evidence from lexical decision and eye movement experiments.

Lexical decision times and eye movements were recorded to determine whether grammatical gender can influence the visual recognition of isolated French nouns. This issue was investigated by assessing the use of two types of regularities between a noun's form and its gender--namely ending-to-gender regularities (e.g., the final letter sequence -at appears only in masculine nouns and, thus, is predictive of masculine gender) and gender-to-ending regularities (e.g., feminine gender would predict the final letter e, whereas masculine gender would not). Previous studies have shown that noun endings are used by readers when they have to identify gender. However, the influence of ending-to-gender predictiveness has never been investigated in a lexical decision task, and the effect of gender-to-ending regularities has never been evaluated at all. The results suggest that gender information can influence both the activation stage (Experiments 1 and 3) and the selection stage (Experiments 2 and 3) of the word recognition process.

Adult↗

Codependency: predictors and psychometric issues.

This study examined the relationships between codependency and age, gender, self-confidence, autonomy, and succorance, which is the quality of soliciting emotional support from others. The study also tested the validity of the Spann-Fischer Codependency Scale (Fischer, Spann, & Crawford, 1991). Ninety-five undergraduates completed a demographic sheet, the Adjective Check List (Gough & Heilbrun, 1983), the Spann-Fischer Codependency Scale, the Co-Dependents Anonymous Checklist (Whitfield, 1991), and a questionnaire developed for this study based on the work of Hemfelt, Minirth, and Meier (1989). As predicted, codependency was negatively related to self-confidence and positively related to succorance. However, contrary to expectation, a negative relationship between codependency and autonomy was not found. In addition, low self-confidence was the strongest predictor of codependency. Finally, all three measures of codependency were strongly related, attesting to the convergent validity of the Spann-Fischer Codependency Scale. Future studies should further investigate the role of emotional autonomy and codependency and should begin to utilize an experimental approach, making predictions regarding the behavior of codependent and noncodependent persons in experimental situations.

Adolescent↗

Addressing diversity in mental health care: a review of guidance documents.

Discriminated against and marginalised groups of people within our communities continue to be over represented within mental health services and frequently their particular needs are not met. Challenging discrimination and working towards more equitable services are a vital part of anyone's role working within mental health services. This paper provides a review of guidance documents on diversity issues with a particular focus on ethnicity, gender, sexuality, learning disability, spirituality, homelessness and age. The review concludes with a summary of the range of approaches that are currently being advocated for translating guidelines and recommendations into improved and equitable mental health services that meet the needs of service users from a wide range of diverse groups.

Attitude of Health Personnel↗

Psychiatric morbidity following motor vehicle accidents: a review of methodological issues.

Motor vehicle accidents (MVAs), even those of a nonserious nature, appear to increase the risk of severe psychiatric morbidity in survivors. The present review examines the evidence indicating the levels of psychiatric morbidity in MVA survivors. Although no consistent profile has emerged, the most commonly reported symptoms are depression, anxiety, irritability, driving phobia, anger, sleep disturbances, and headache, with rates of posttraumatic stress disorder (PTSD) across studies of 0% to 100%. Variability in the type and severity of psychiatric outcomes may be due, in part, to methodological inadequacies in many studies, particularly the use of biased population samples, inclusion of subjects exposed to varied types of accidents, an absence of a clear definition of PTSD, a reliance on clinical judgment rather than the use of objective psychometric measures, the failure to include ratings of injury severity, and the absence of assessments for past exposure to traumatic events or preexisting posttraumatic reactions. The most important concern relates to the use of nonrepresentative samples, usually patients referred for medicolegal assessment in whom issues of compensation are of central importance. Gender and age differences distinguish the compensation group from the general population of MVA survivors, who therefore may also differ in the vulnerability to posttraumatic morbidity. It is argued that more systematic research on unselected subject samples is critical to establish epidemiological data on the true nature and extent of psychiatric morbidity following MVAs.

Accidents, Traffic↗