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PubMed1983

[Total serum and non-conjugated estriol in the 3d trimester of pregnancy. Inter-individual, intra-individual variations during the day and from one day to another. Study of at-risk pregnancies].

It is possible to estimate the daily rate of oestriol production by the fetoplacental unit to monitor pregnancy by radio-immunoassay of the concentrations of unconjugated and total oestriol in the serum. The usefulness of these two parameters was compared by comparing variations from day to day in the same individuals and between them and other individuals, as well as over 24 hours. We think the best choice of test for biochemical monitoring of at-risk pregnancies is the estimation of unconjugated oestriol because there is a lower day to day variation in the same individual as well as throughout the 24 hours.

Adult↗
PubMed1984

[The effect of calf blood dialysate on the excretion of estriol in placental insufficiency].

The efficacy of a dialysate of calf blood in the treatment of chronic placental insufficiency is assessed using the urinary oestriol elimination as parameter. Compared with a control group, those cases receiving 2 times 250 ml protein-free dialysate of calf blood (Solcoseryl) in saline solution over 9 days showed a significant increase in the daily quantity of urinary oestriol elimination already from the second day of treatment onwards. Other conventional procedures in the medical treatment of placental insufficiency are discussed. Some of these are known to have secondary effects or must be regarded as invasive.

Actihaemyl↗
PubMed1978

Unconjugated estriol and cortisol in maternal and cord serum and amniotic fluid in normal and abnormal pregnancy.

This study investigated unconjugated E3 and cortisol in normal and abnormal (diabetes and chronic stress) pregnancies and the compartmental (maternal, fetoplacental, amniotic fluid) concentrations and relationships in simultaneous samples. It was demonstrated that in labor both steriods are higher in all compartments than in patients having an elective cesarean section. Diabetic pregnancies do not differ radically from normal, but the stressed gestations have lower E3 and elevated fetal cortisol levels. That the maternal serum unconjugated E3 reflected fetoplacental function was confirmed. Twin pregnancies that were studied presented some conflicting data.

Adrenal Glands↗