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Colour blindness.

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Color Perception↗

[Daltonism].

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Color Perception↗

[Color blindness].

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Color Perception↗

The fundamentals of color perception. Charles F. Prentice Award Lecture--1977.

The author raises the question, "Suppose a newly qualified optometrist announced that he wanted to undertake research on the perception of color; what fundamental elements of the subject should he attempt to master before setting out on his research program?" In answering this question, the author traces his own development in the subject of color vision.

Awards and Prizes↗

Foveal vision function before and after fluorescein angiography.

PURPOSE: Fluorescein angiography is routinely used in ophthalmologic practice with minimal changes in vision reported by the patient after the procedure. Recent animal work has suggested that fluorescein may be cytotoxic in the presence of light and may cause retinal damage. The authors examined whether any changes occur in foveal vision function after fluorescein angiography. METHODS: A battery of tests of vision function--including visual acuity, contrast sensitivity, color vision, and two-color increment thresholds designed to isolate individual cone pathways--was administered before and 48 hours after fluorescein angiography to a group of 10 patients with good visual acuity. RESULTS: Most of the patients showed significant abnormalities with the nonstandard tests; however, no significant changes in central vision function were found 48 hours after fluorescein angiography. CONCLUSION: Even sensitive vision tests show no measurable effect of fluorescein angiography on foveal vision function in eyes with significant disease.

Adult↗

Color discrimination in carriers of color deficiency.

Carriers of X-linked color vision deficiencies have previously been reported to exhibit mild abnormalities of color matching and discrimination. In a sample of 55 carriers of protan and deutan deficiencies and 55 age-matched normal controls, we measured chromatic discrimination along a red-green axis. We found that discrimination was impaired in the case of carriers of deutan deficiencies (which affect the middle-wave-sensitive cones of the retina), but was normal in the case of carriers of protan deficiencies (which affect the long-wave-sensitive cones). We argue that this result can be explained by the difference in the relative numbers of middle- and long-wave cones in heterozygous retinae: the imbalance of the two cone types is predicted to be much greater in the case of the deutan heterozygote than in the case of the protan heterozygote. In future studies it will be necessary to consider separately the two types of heterozygote.

Adult↗

Performance of red-green color deficient subjects on the Farnsworth Lantern (FALANT).

BACKGROUND: The Farnsworth Lantern (Falant) is an occupational color vision test intended to identify people with significant red-green color deficiency who are unable to name aviation, marine or railway signal lights correctly. The colors shown are white, green and red selected to be within protan and deutan isochromatic zones. HYPOTHESIS: The Falant grades the severity of color deficiency and identifies subjects with different types of deficiency. METHOD: 270 color deficiency subjects (diagnosed with the Neitz anomaloscope) were examined. A subset of 108 subjects also completed the Farnsworth D15 and the Farnsworth-Munsell 100 hue test. RESULTS: All dichromats and 75% of anomalous trichromats failed the Falant. The mean error score of dichromats was greater than that anomalous trichromats, but errors were made in a similar number of qualitative color naming categories. The range of Falant error scores was continuous with no demarkation between the criteria for pass and fail. It was not possible to identify anomalous trichromats likely to pass the Falant from the size of the anomaloscope matching range or from the results of Farnsworth-Munsell tests. CONCLUSIONS: People with severe red-green color deficiency fail the Falant, but neither the type nor the severity of color deficiency can be determined either from the qualitative results or from the error score.

Aviation↗

Temporal integration of the pi 1/pi 3 pathway in normal and dichromatic vision.

Stiles' pi 1 and pi 3 mechanisms are thought to reflect adaptation events at two sites in a single pathway, the first site controlled by the short-wavelength cones alone, the second site controlled by opposing signals from these cones vs the other cone classes. We examined this pathway's temporal integration under conditions that yield the full gamut of possible adaptation states at the two sites. Critical duration of the pi 1/pi 3 pathway was always about 200 msec. In addition, we examined the pi 1 and pi 3 mechanisms of dichromatic vision. Our results suggest that protanopic and deuteranopic vision are characterized by a pi 1/pi 3 pathway similar to that in normal color vision.

Color Perception↗