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PubMed1989

[Cognitive processes in unconscious patients? A brain mapping study of the P300 potential].

P300 is the most investigated component of the event-related potentials. Being the correlate of an active target discrimination and decision making process it is seen as related to cognition. Such elementary cognitive processes--as expressed in P300--can happen even in states of coma. In four of 35 comatose patients with diffuse head injury we were able to measure the P3-wave showing frontal and parietal components. Accordingly some unawakable patients can still recognize differences in pitch. The structure of components and their psychophysiological meaning are discussed.

Adult↗
PubMed1987

[Neurologic mechanism of the unconscious craving for alcohol in chronic alcoholic patients].

The author studied cortical mechanisms of the perception of subconscious motivationally meaningful word "vodka" in patients with chronic alcoholism. Clear-cut diffuse activation of the cerebral cortex in response to a subconscious verbal stimulus was identified through recording evoked cortical potentials which are a sensitive indicator of reactivity of the cerebral structures to alcohol. The elucidated cortical activation may be one of the nervous mechanisms of stable craving for alcohol which is poorly controlled by the patient's conscious experience.

Adult↗