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At least 1,441 records · Page 80Linked to original sources
PubMed1992

Vertical dimension increases in the adult rhesus monkey: a pilot study.

Tooth impaction, increased muscle activity, and histologic changes in the bone of the temporomandibular joint have been reported following attempts to increase the vertical dimension of occlusion. The purpose of this research was to study the effects of increases in the vertical dimension of occlusion on bone density at five levels of the mandible in the adult rhesus monkey, and to assess dentoalveolar changes by lateral cephalometric radiographs and mounted diagnostic casts. Mandibular cobalt chromium splints measuring 3 mm in height at the first molar, providing even occlusal contact to the maxillary anterior and posterior teeth, were cemented in place on two monkeys. Five similar monkeys without splints were used as controls. Computed tomograms were completed to evaluate bone density bilaterally at five levels of the mandible after 3 months of splint wear. Pretreatment and posttreatment lateral cephalometric radiographs and mounted diagnostic casts were completed to assess tooth impaction. Periodontal ligament (PDL) thickening and mobility of molars and premolars were evaluated before splint placement and after splint removal. There was no statistically significant difference in the bone density levels of the animals with splints compared with the controls. Minimal dentoalveolar changes were observed.

Animals↗
PubMed1994

Clinical epidemiologic concerns and the geriatric prosthodontic patient.

Investigations of the oral health of the elderly leave little doubt that disease and dysfunction are plentiful, although there is some debate on how the clinical observations translate into treatment needs. The problems appear to be greatest among the disabled and the institutionalized, whereas dentists generally show little enthusiasm for offering their services outside the confines of the traditional dental practice. Consequently the oral health concerns in the older population, and especially as they relate to prosthodontic treatment, remain substantially unanswered.

Aged↗
PubMed1984

Specific impairment of BAER's in Friedreich's ataxia. Auditory evoked responses in clinical evaluation and differential diagnosis.

We have investigated brainstem and cortical auditory responses (BAERs and CAERs) in 16 cases of Friedreich's ataxia (FA) and have compared the findings with those obtained in 2 cases of familial spastic paraplegia (FSP), in 5 cases of Charcot-Marie-Tooth disease (CMTD), and in 6 cases of atypical FA of uncertain classification. BAERs could not be elicited in 11 FA patients and constantly disappeared at a higher intensity threshold than in normal subjects in the remaining 5 patients. BAERs were normal or only slightly abnormal in FSP and CMTD patients. CAERs were normal in all 29 patients. BAERs tended to disappear with the progression of FA and BAER thresholds were correlated with the Inherited Ataxias Clinical Rating Scale score, which is an index of the severity of illness. BAERs contributed to the diagnosis, or exclusion of FA in patients with an atypical picture. It is suggested that in FA myelinated fibers in the spiral ganglion are partially affected, resulting in the decrease of wave amplitude such as occurs for peripheral sensory potentials.

Adolescent↗
PubMed1990

Degradation of connectin (titin) in Fukuyama type congenital muscular dystrophy: immunochemical study with monoclonal antibodies.

Connectin (also called titin) is a myofibrillar elastic filament which links a thick filament to a neighbouring Z line in a sarcomere and thus contributes significantly to the elasticity of myofibrils. In a previous study, we demonstrated by Western blot analysis of the biopsied skeletal muscles using an anti-connectin monoclonal antibody that connectin was degraded extensively after 5 years of age in Duchenne muscular dystrophy (DMD), while it was degraded mildly in Becker muscular dystrophy and only minimally in myotonic dystrophy, limb girdle dystrophy, amyotrophic lateral sclerosis and Charcot-Marie-Tooth disease. In the present study, we investigated the degradation state of connectin in Fukuyama type congenital muscular dystrophy (FCMD) by a similar method using 2 distinct anti-connectin monoclonal antibodies. In FCMD, connectin degradation began much earlier than in DMD: Definite degradation was already observed in 5-8-month-old patients. It was presumed that connectin degradation would play an important role in the myofibrillar degeneration in the early stage of FCMD.

Antibodies, Monoclonal↗
PubMed1976

Localization of objects in the anterior areas with a single Panorex radiograph.

Impacted objects in the anterior dental region can be localized in a labial-palatal direction with a single Panorex film. Clark's rule is applied to the two views of the anterior area obtained. The technique is verified by means of a dry skull with lead markers in known positions, and two clinical cases are reported.

Adult↗
PubMed1981

Actinobacillus actinomycetemcomitans infection in the oral cavity.

An abscess that developed following the extraction of periodontally involved teeth persisted after surgical drainage and ampicillin therapy. Subsequent culture of pus from this abscess gave a pure growth of Actinobacillus actinomycetemcomitans which was resistant to ampicillin. Surgical drainage and the use of appropriate antibiotic therapy cleared the infection. The identification of A. actinomycetemcomitans and the types of infection it causes are described. The probable mechanism of infection by the bacterium is discussed. A case that illustrates the importance of the microbiologic examination of pus from dental abscesses is reported.

Abscess↗
PubMed1982

The effects of different splinting times on replantation of teeth in monkeys.

The purpose of the study was to examine histologically the tissue changes affecting the teeth and surrounding structures after using both 7- and 30-day fixation periods on replanted teeth in monkeys. Eight adult male rhesus monkeys were used. The maxillary central and lateral incisors were extracted, treated endodontically, reimplanted, and temporarily immobilized with an interproximal acid-etch splint. The splints were removed at 1 week in half of the teeth and at 30 days in the other half. The monkeys were killed at 7 and 14 days, and at 1, 2, 3, 4, 5, and 6 months postoperatively. The results showed that replanted teeth that were splinted for 7 days recovered uneventfully, whereas the teeth that were splinted for 30 days demonstrated increased areas of root resorption and ankylosis. Thus, it is suggested that after tooth replantation the periodontium will repair rapidly with a shorter time of splinting (7 days). Extended splinting periods (30 days) seem to induce further root resorption and dentoalveolar ankylosis.

Animals↗