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Results for “monkeypox”

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PubMed2003

Antiviral activity of cyclopentenyl nucleosides against orthopox viruses (Smallpox, monkeypox and cowpox).

An improved method for the synthesis of enantiomerically pure D-cyclopentenyl nucleosides has been accomplished and their antiviral activity against orthopox viruses have been evaluated. The key intermediate, L-cyclopent-2-enone 13 was prepared from D-ribose using a ring closing metathesis reaction in eight steps. Among the synthesized nucleosides, the adenine 2 (Neplanocin A), cytosine 14, and 5-F-cytosine 15 analogues exhibited potent anti-orthopox virus activity, including smallpox virus.

Adenosine↗
PubMed2004

Human monkeypox.

Explore the source record for details and available documents.

Adult↗
PubMed2003

SARS: here to stay? Monkeypox: beware of exotic pets.

Severe acute respiratory syndrome (SARS) is probably here to stay, and every health care institution should take precautions against an outbreak. The signs and symptoms of SARS are nonspecific, and there is no early diagnostic test, no specific treatment, and no vaccine. In some parts of the world, including Canada, more than 80% of probable cases were nosocomial.

Humans↗