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At least 145 records · Page 8Linked to original sources

Obstructive leiomyoma of the female urethra: report of a case.

We report a case of leiomyoma of the female urethra and review the literature. A mass protruding from the urethral meatus during voiding caused dysuria. Urodynamic study showed an obstructive pattern with low maximum urine flow and high detrusor pressure in initiating voiding. Cystourethroscopy revealed a mass extending from the proximal segment of the left lateral urethral wall into the bladder. At transurethral resection of the tumor 12.2 gm. of tissue were excised. Histopathological studies confirmed urethral leiomyoma. Surgery completely resolved the original symptoms of dysuria.

Female↗

A stage specific approach to tumor surveillance after radical cystectomy for transitional cell carcinoma of the bladder.

PURPOSE: Surveillance protocols after radical surgery for genitourinary tumors typically do not consider that the risk of recurrence is stage dependent. We describe the development of a stage specific protocol for monitoring patients with transitional cell carcinoma for tumor recurrence and conduit complications after radical cystectomy. MATERIALS AND METHODS: The records of 382 patients with transitional cell carcinoma who underwent cystectomy in 1986 to 1994 were reviewed for the dates and presenting symptoms of local and distant recurrences, and the results of radiological imaging studies and liver function tests. Based on the division of patients into pathological stages of pT1, pT2 and pT3 groups, we developed a new transitional cell carcinoma surveillance protocol. RESULTS: Of 97 patients with transitional cell carcinoma metastases 72 (74%) were asymptomatic, including 43 with metastases detected by routine chest x-rays (30) or blood tests (13). Surveillance computerized tomography identified isolated asymptomatic intra-abdominal metastases in 10 patients (10%), of whom 90% had pT3 disease. Based on these results we recommend a stage specific surveillance protocol for pT1--annual history, physical examination, chest x-ray and laboratory studies, pT2-same studies at 6, 12, 18, 24, 30, 36, 48 and 60 months after cystectomy, and pT3-same studies at 3, 6, 12, 18, 24, 30, 36, 48 and 60 months plus computerized tomography at 6, 12 and 24 months after cystectomy. A radiographic study of the upper tract should be performed in all patients every 1 to 2 years to evaluate for recurrences and complications of the ileoureteral anastomosis. CONCLUSIONS: A stage driven surveillance strategy for monitoring patients after radical cystectomy can reduce costly imaging studies while efficiently detecting recurrences and complications.

Carcinoma, Transitional Cell↗

Bulbous urethra involved in perineal extraskeletal myxoid chondrosarcoma in a child.

Extraskeletal myxoid chondrosarcoma is a rare soft-tissue sarcoma that usually occurs in deep soft tissues, especially those of the proximal extremities and limb girdles, but is rare in children. We present an unusual case of a tumor arising in the perineum and involving the bulbous urethra in a 21-month-old boy. The patient was treated with surgical excision and urethroplasty followed by combination chemotherapy.

Chondrosarcoma↗

Role of continent suprapubic diversion in pelvic cancer.

Seventeen patients with either current (n = 14) or previous (n = 3) pelvic malignant disease underwent continent urinary diversion using the Mitrofanoff principle in 16 and a Kock pouch in 1. Eight patients had bladder carcinoma, 6 had gynaecological malignancy, 2 had rectal cancers and 1 had a squamous cell carcinoma of the perineum. Fourteen underwent synchronous exenterative surgery and continent suprapubic diversion; plastic reconstructive procedures were required in 4. There were 2 post-operative deaths and 5 patients have developed further tumour recurrence. Continence was satisfactory in all patients with a median interval of intermittent self-catheterisation of 4 h.

Abdominal Muscles↗