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At least 145 records · Page 8Linked to original sources

Utilization of telemetry system to assess the cardiovascular profile of AH-1058, a new cardioselective Ca2+ channel blocker, in conscious dogs.

Cardiovascular effects of a new Ca2+ channel blocker AH-1058, 4-(5H-dibenzo[a,d]cyclo-hepten-5-ylidene)-1-[(E)-3-(3-methoxy-2-nitro)phenyl-2-propenyl]piperidine hydrochloride, were assessed in conscious dogs using a new telemetry system. AH-1058 (0.03, 0.1 and 0.3 mg/kg, i.v.) reduced systolic blood pressure and the maximal upstroke velocity of the left ventricular pressure and increased the heart rate in a dose-dependent manner without affecting the diastolic blood pressure; each of these responses lasted for several hours. These results support the previous knowledge that AH-1058 is a long-lasting cardiodepressive drug. The telemetry system provided important information for predicting favorable clinical effects of AH-1058.

Animals↗

Mobile telemetry for pre-hospital thrombolysis: problems and solutions.

In the Angus region of Scotland, we have used mobile telemetry to facilitate pre-hospital thrombolysis by paramedic staff. An initial survey demonstrated that connection could be achieved in all but three locations. In the first year of operation, 229 contacts were received. Communication between the ambulance and the base station failed on four occasions (2%). Problems with transmission of an electrocardiogram (ECG) were encountered on 37 occasions (16%). The median time for acquisition and transmission of an ECG was 22 min. This compares with a median time of 59 min for first ECG in a control group from similar locations, who were assessed in hospital. Telemetry offers essential back-up to paramedics adopting a challenging and extended role. Strategies can be developed to deal with signal strength and equipment failure.

Cohort Studies↗

A multiparameter, PC-based telemetry unit for biomedical signals.

A low-cost, general-purpose telemetry system was developed for use in rural health centres, hospitals, ambulances and clinics. It was designed to transmit a range of analogue biomedical signals using various communications media. The system was tested using different telephone systems, including mobile telephony. The results showed a maximum sample rate of 1.6 kHz using the public telephone network. With three data channels the system produced sample rates of 500 Hz at 8 bit/sample. Typical overall delay times were below 100 ms. Mobile tests showed that the GSM telephone was superior to the Nordic mobile telephone (NMT 900). In field tests, sample rates of 990 Hz were obtained using GSM telephony. Bit error rates were less than 10(-7) for all applications and high-fidelity regeneration was obtained at the receiver. The tests showed that the system was well suited for telemetry of analogue biomedical signals in a broad range of telemedicine applications.

Ambulances↗

Kater-Karlsruhe Telemetry Test in Rescue Services.

The Karlsruhe Telemetry Test in Rescue Services (KATER) investigates the central role of the regional emergency dispatch center as the midpoint of the emergency medicine information network using ECG telemetry, in order to be able to draw conclusions for future development. Rescue centers today form the logistic center of the flow of information. Expanding this legally formulated role to data flows within a network is just beginning, however, since the introduction of EDP in pre-clinical emergency medicine is still in the pilot project stage. Legislators are tending toward big solutions due to economic reasons. The increasing complexity of this problem can only be handled by a networked infrastructure.

Computer Communication Networks↗

Studies of ambulance patients with ischemic heart disease. 1. The outcome of pre-hospital life-threatening arrhythmias in patients receiving electrocardiographic telemetry and therapeutic interventions.

Patient delay in seeking medical assistance for acute ischemic heart disease and the incidence of potentially life-threatening arrhythmias en route to the hospital were examined in a 22-month community trial of ambulance telemetry. Of 7,654 patients transported, 179 who had electrocardiograms (ECGS) transmitted were found to have had acute MIs or acute myocardial ischemic events. Fifty per cent of these patients summoned an ambulance within 30 minutes and 72 per cent within two hours after the onset of acute symptoms. Fifty-eight patients had potentially life-threatening arrhythmias. Interventions with drugs and/or defibrillation was required in 22 patients with or without cardiopulmonary resuscitation (CPR); intervention with CPR alone was required in six patients. Twelve of these 28 patients survived through hospital admission and six were alive at three months. The relatively low outcome/input ratio of this experience necessitates re-evaluation of the epidemiological characteristics and patient selection criteria in populations considered for telemetry.

Aged↗

[Occlusal contacts of complete denture during mastication in telemetry system].

The purpose of this study was to develop a telemetry system and to analyze the occlusal contacts of complete denture during mastication. The telemetry system consisted of a transmitter unit and a receiver unit. The transmitter allowed 6 channels of information of the occlusal contacts to be telemetered by time division multiplex communication method within the approximate distance of 2 m. The occlusal surface of the upper complete denture was made of metal and that of the lower denture was made of metal contact plates of 0.5 mm in width with each space of 0.5 mm. Then the transmitter was embedded in the lower complete denture. Occlusal contacts of 66 aged edentulous male were investigated both on the chewing side and on the nonchewing side in the premolar, the 1st molar and the 2nd molar regions. The results were as followed: 1. The occlusal contacts in the nonchewing side preceded those in the chewing side, with higher frequency and longer duration. 2. In the nonchewing side, the occlusal contact occurred at different time; the occlusal contact was observed first in the 2nd molar, then 32-48 ms later in the 1st molar, and 2-48 ms later in the premolar regions. 3. It is suggested that the balancing contact should be considered for stabilizing the denture in mastication.

Dental Occlusion↗

Voluntary telemetry control of functional electrical stimulators.

With the assistance of crutches and functional electrical stimulation (FES) we are able to restore standing and simple gait in some spinal cord injured (SCI) patients. In the present rehabilitative systems the patient divides the gait cycle into 'stance' and 'swing' phase by using pushbuttons mounted in the handles of the crutches. These are then hard wired to the functional electrical stimulator. We present the development and evaluation of a surface mount technology based telemetry system that provides reliable and interference resistant wireless control of FES assisted walking. The system makes use of radio frequency carriers operating at a frequency of 40 MHz. Crutch pushbutton signals are coded and transferred from the transmitter placed in the crutch to the receiver which is firmly attached to the patient's waist and connected to the stimulator. The telemetry system was found to be of special importance for both complete and incomplete SCI subjects and is currently in use at the Rehabilitation Institute of the Republic of Slovenia.

Activities of Daily Living↗

Chronic monitoring of cardiovascular function in the conscious guinea pig using radio-telemetry.

An implantable radio-telemetry device for chronic monitoring of arterial pressure and heart rate in the conscious guinea pig was validated against measurements using an exteriorized, indwelling catheter. There were no significant differences between simultaneous measurements in animals instrumented with both the telemetry system and the conventional catheter (implanted 24 hrs prior to comparisons) in response to a variety of vasoactive agents. The device was shown to be accurate up to 3 weeks after implantation (longest time point tested). Resting pressures and heart rates in the telemetered guinea pig were stable in 100% of the animals tested. In contrast, animals instrumented with only exteriorized catheters showed a significant decline in pressure by 8 days after surgery and a 39% attrition rate due to loss of catheter patency. Performance of the telemetric device was examined in both normal and sodium-deficient animals, since the latter is a useful normotensive model in which blood pressure is rendered highly renin-dependent for evaluating the efficacy of potential antihypertensive agents that target the renin-angiotensin system. The telemetered guinea pig is an appropriate model for assessing responses to chronic exposure of cardiovascular agents.

Animals↗

Validation of a telemetry system for measurement of blood pressure, electrocardiogram and locomotor activity in beagle dogs.

A model is described for the continuous recording of arterial blood pressure, electrocardiogram and locomotor activity by telemetry in conscious unrestrained beagle dogs. Validation of the system was accomplished by simultaneous acute catheterisation and telemetry recording ten weeks after implantation, under anaesthesia. Systolic, mean and diastolic pressures, measured over 30-40 mm Hg, were not significantly different. Telemetric measurements in their home cage over several days revealed clear diurnal variations in blood pressure, heart rate, locomotor activity and contractility (QA-interval). Despite these diurnal variations the 24 h mean values were highly reproducible. This model was further characterised by pharmacological interventions designed to increase contractility (ouabain) and blood pressure (NG-nitro-L-arginine methyl ester) and to lower blood pressure (isosorbide-5 mononitrate and molsidomine). The high daily reproducibility of cardiovascular parameters allowed each dog to be used as its own control and allowed investigation of these long-acting active agents, which would not have been possible with conventional methods for cardiovascular measurement. These findings demonstrate the utility of this model for investigations into blood pressure regulation as well as the potential for pharmacological intervention.

Animals↗

A pressure-balanced radio-telemetry system for the measurement of intracranial pressure. A preliminary design report.

A fully implantable radio-telemetric differential intracranial pressure sensor is described with a zero-point calibration that can be confirmed repeatedly. Intracranial pressure (ICP) is measured with the device by the principle of applying a known external pressure to the scalp above the sensor and simultaneously detecting by radio-telemetry the zero-point of the sensor corresponding to a balance of pressures across it. The radio-telemetry is implemented by a resonant circuit in the sensor of which the resonant radiofrequency is detected outside the body. The sensor is passive, has built-in barametric compensation, negligible permeability of temperature drift, no calibration ambiguities, and fast dynamic response. The implanted sensor has been used successfully for short-term as well as long-term ICP monitoring. It has been implemented primarily for intermittent ICP measurements, but also adapted to continuous recording. Preliminary clinical experience with the system indicates that it is effective, safe, and simple to operate.

Electronics, Medical↗

Making tough decisions about telemetry monitoring.

Telemetry monitoring, when used effectively and appropriately, is beneficial and plays an important role in enabling primary caregivers to provide optimum care for their patients. However, it is frequently used ineffectively and inappropriately, which can be extremely costly for hospitals. In this era of health care reform, careful review of this technology and analysis of telemetry utilization can avoid unnecessary expenditures or abuse.

Bed Occupancy↗

Biomedical telemetry transmitters--FCC. Final rule.

By this Report and Order, the Commission amends its regulations regarding the unlicensed operation of biomedical telemetry transmitters in the 174-216 MHz (TV channels 7-13) and 470-668 MHz (TV channels 14-46) bands as proposed in the Notice of Proposed Rule Making ("Notice") in this proceeding, 61 FR 3367, January 31, 1996. These amendments will provide patients in health care facilities the ability to move about in a limited area while being continually monitored, speeding patient recovery times, shortening lengths of stay, and reducing health care costs. The standards being adopted for these devices should protect the licensed services operating in the TV bands. Further, a coordination procedure has been implemented to protect radio astronomy observatories from potential interference from biomedical telemetry systems operating on 608-614 MHz (TV channel 37).

Government Agencies↗

Let's talk telemetry.

As telemetry becomes more prevalent, the lines between medical device and clinical information system begins to blur. The author explains why telemetry is growing and merging with traditional information systems and the issues this creates.

Hospital Information Systems↗

[Telemetry: the importance of surgical aspects].

Telemetry allows the monitoring of multiple parameters, such as blood pressure, temperature, motor activity and ECG, without any stressful handling or restraint. The invasive phase (i.e. the surgical implantation of a transmitter), which takes place before the start of the study, is of critical importance. Good surgical techniques as described below are essential. All risks of trauma or infection should be avoided, particularly if the animals are to be used in long-term studies. The utility of telemetry may be complemented with other atraumatic techniques, for instance the use of indwelling i.v. infusion catheters allowing long-term studies without any extrinsic stress resulting from the dosing procedure or routine examinations.

Electrodes, Implanted↗

[A multichannel infrared telemetry system for physiological signal].

This paper introduces the multichannel infrared telemetry system for temperature, respiration and ECG measurements. The experimental results are given at the end of the paper. This infrared telemetry system can be used in the environment with high electromagnetic interference, such as the operating room with electrosurgical unit and become an important monitor device.

Electronics, Medical↗

[Design of a infrared single-channel ECG telemetry system].

A single-channel ECG telemetry system with infrared rays as the medium was designed. It can be used to monitor the subject's ECG in real-time. This system has functions of detecting abnormal ECG, alarming, dieplaying, storing and printing. It is a beneficial attempt in the clinical application of the infrared telemetry.

Electrocardiography↗

Recording of blood pressure, heart rate and aortic nerve activity during parabolic flight in the rat via radio-telemetry.

Exposure to microgravity induces cardiovascular deconditioning characterized by orthostatic hypotension when astronauts return to the earth. In order to understand the mechanism of cardiovascular deconditioning, it is necessary to clarify the changes in hemodynamics and the cardiovascular regulation system over the period of space flight. The telemetry system applied to freely moving animals will be a useful and appropriate technique for this kind of long term study of the cardiovascular system in the conscious animal during space flight. The purpose of the present study is twofold: firstly, to observe the detailed changes of arterial pressure and heart rate (HR) during microgravity elicited by the parabolic flight in order to study the acute effect of microgravity exposure on the cardiovascular system; and secondly, to test the feasibility of the telemetry system for recording blood pressure, HR and autonomic nervous activities continuously during space flight.

Animals↗

A modified plaque pH telemetry method.

Previous plaque-pH telemetry studies reported the acidogenicity of various foods and dietary patterns to estimate potential cariogenicity. To avoid patient discomfort, improve compliance, and minimize electrode malfunctions, we have simplified our telemetry method and compared it to our previously published model. A removable partial prosthesis with a glass electrode set in the approximal space left by a missing first molar was used in 2 subjects. In the modified method, subjects suspended oral hygiene for 3 days, the prosthesis was then installed on the 3rd day, and accumulated plaque was spread on the electrode and covered with gauze for retention. In comparative tests, the same subjects wore the prosthesis in the mouth during plaque accumulation. Test sessions compared the plaque pH response to 4 treatments: a 10% sucrose rinse, a 10% sorbitol rinse, a snack roll with marmalade and coffee, and the snack followed by gum chewing. Overall, pH curves were similar (mean baselines and minimas) and no significant differences in mean pH response were noted between the 2 methods. The modified method improved subject participation, demonstrated greater reliability, and showed Stephan curves comparable to conventional methods.

Cariogenic Agents↗