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Local hemostasis after tooth extraction in patients with abnormal hemostatic function. Use of human fibrinogen concentrate.

Tooth extraction was carried out in 405 patients with various hemostatic disorders due to thrombocytopenia, chronic liver disease, hemophilia A and B, von Willebrand's disease and oral anticoagulants. Human fibrinogen concentrate was used as local hemostatic agent. Prophylactic replacement therapy (platelets or plasma concentrates) and antifibrinolytic agents were not administered. Oral anticoagulants were not discontinued. Minor postextraction bleeding occurred only in severe hemophilia A and occasionally in the oral anticoagulant group.

Blood Coagulation Disorders↗

Secondary abscess formation in pituitary adenoma after tooth extraction. Case report.

The presence of an abscess in a pituitary tumor is a very rare finding. The authors report the case of a 69-year-old man with a pituitary adenoma confirmed by neuroimaging results, in whom a high fever, meningismus, and left-sided ophthalmoplegia developed 4 days after tooth extraction. The results of serial cranial magnetic resonance imaging were highly indicative of an abscess formation within the pituitary adenoma. During surgery the tumor was approached transsphenoidally and removed. Histological examination confirmed the presence of an abscess formation within the pituitary adenoma. It is most likely that the tooth extraction caused a bacteremia, which led to an inflammation with abscess formation within the pituitary adenoma. The authors conclude that invasive dental procedures should be avoided before planned resection of a pituitary adenoma.

Adenoma↗

[Veterinary dentistry (4). Tooth extraction in dogs].

In this paper of a series on small animal dentistry tooth extraction in dogs will be discussed. A review of indications for extractions, basic instrumentation, extraction techniques and their complications in dogs are described.

Animals↗

[The role of fibrinolysis in the pathogenesis of alveolitis after tooth extraction. Preliminary report].

We registered fibrinolytic activity of blood within fresh wounds after tooth extractions by means of measuring fibrinolysis in vitro. In cases which later developed alveolitis we found higher degrees of fibrinolysis. Women taking oral hormonal contraceptives showed fibrinolysis to a greater extent than other women or men. We found more fibrinolytic activity in cases with longer extraction times. Possible starting points for prevention of alveolitis are discussed.

Contraceptives, Oral, Hormonal↗

Ridge preservation using HTR synthetic bone following tooth extraction.

Use of HTR (synthetic bone graft material) has been described to make tooth extraction a more controlled, regimented procedure. Strict adherence to surgical technique, with emphasis on appropriate suturing, is necessary to produce consistently successful results. A variation of an interrupted suture technique, the double-mattress stitch, is described in detail to achieve these results. This suturing method is replicable and applicable to most areas of the mouth. This technique is more challenging (but not impossible) to perform in areas that are difficult to access, such as in maxillary third molar regions. This stitch is essential for closing the extraction site and containing the graft material during initial healing. An ideal bone graft material should prevent postextraction osteitis, and maintain bone in the extraction area and proximal to this site. HTR satisfied these requirements.

Alveolar Bone Loss↗

Reasons for permanent tooth extractions in Japan.

BACKGROUND: There has been no nationwide study in Japan on reasons for extraction of permanent teeth. This survey was aimed to determine the reasons for extraction of permanent teeth in Japan. METHODS: Five thousand, one hudred and thirty-one dentists were selected by systematic selection from the 2004 membership directory of the Japan Dental Association. The dentists selected were asked to record the reason for each extraction of permanent teeth during a period of one week from February 1 through 7, 2005. Reasons for tooth extraction were assigned to five groups: caries, fracture of teeth weakened by caries or endodontics, periodontal diseases, orthodontics, and other reasons. RESULTS: A total of 2,001 dentists (response rate of 39.1%) returned the questionnaires, and information on 9,115 extracted teeth from 7,499 patients was obtained. The results showed that caries and its sequela (totally 43.3%, 32.7% and 10.6%, respectively) and periodontal disease (41.8%) were the main reasons for teeth extraction. Extraction due to caries or fracture was commonly observed in all age groups over 15 years of age, whereas periodontal disease was predominant in the groups over 45 years of age. CONCLUSIONS: Most of the permanent teeth were extracted due to caries and its sequela and periodontal disease. Prevention and care for dental caries for all age groups and periodontal disease for over middle age groups are required.

Adolescent↗

[The bacteriology of normal wound healing following tooth extraction with special reference to anaerobic microorganism diagnosis].

In 10 patients with indication to tooth extraction swaps from the microbiotopes "sulcus/gingival pocket", "root canal", "socket" and "extraction wound 2 and 7 days after extraction" were investigated bacteriologically. The anaerobic-aerobic mixed flora with predominance of anaerobes verified in the microbiotopes "sulcus/gingival pocket", "socket" and "extraction wound 2 days after extraction" was identically. The flora of the root canal was distinguished by a smaller amount of microbes with predominance of aerobes. In the 7 days old extraction wound only single aerobes could be verified whereas anaerobes were missed totally.

Alveolar Process↗

Factors affecting the occurrence of bacteremia associated with tooth extraction.

This study examined the factors that affect the occurrence of bacteremia associated with tooth extraction and the kinds of bacteria causing this bacteremia. Bacteremia was found in 132 (72.1%) of 183 patients who had one or more teeth extracted for various reasons. Bacteremia occurred more frequently when teeth were extracted because of inflammatory dental diseases. The occurrence of bacteremia also increased with the number of teeth extracted and the age of the patients. When the volume of blood lost during surgery was > 50 ml and the time required for the operation exceeded 100 min, the occurrence of bacteremia was also higher. Anaerobes were isolated from 104 (78.8%) of the 132 cases of bacteremia. Of the 187 isolates obtained, three (1.6%) were aerobes, 51 (27.3%) were facultative anaerobes (including microaerophils), and 133 (71.1%) were anaerobes. Among facultative anaerobes and microaerophils, the most frequently isolated bacterial genera were Lactobacillus (n = 15), Streptococcus (n = 13), and Staphylococcus (n = 12); and among anaerobes, Eubacterium (n = 40), Peptostreptococcus (n = 40), and Propionibacterium (n = 20).

Adolescent↗

Research into changes in canine maxillary trabecular bone orientation after tooth extraction.

This paper described the morphological changes in the trabecular bone orientation of the jaw bone due to reduction in the applied functional pressure. All teeth on the right side of the upper and lower jaws were extracted from canine specimens. Experimental periods were set at 0.5, 1, 1.5, 2, 2.5, 3, 5, 7, 9, 11, and 13 months after tooth extraction. The trabecular bone orientation was measured by an image analyzer as morphometrical parameters. The loss of teeth changed the support system for functional pressure, resulting in the marked disordering of the trabecular bone orientation.

Alveolar Process↗

A study of the reasons for tooth extraction in a Canadian population sample.

The reasons for extraction of teeth were determined in a Canadian population sample of 909 patients, ranging in age from 14 to 91 years. Caries was the primary cause of extraction (63%), followed by periodontitis (34%). For the adult age groups, the percentages were approximately the same. While periodontitis was the cause of one-third of the extractions, these occurred in only one-fifth of the population. Although there is a commonly expressed belief that periodontitis is the major cause of tooth loss in adults, a review of both historical and contemporary literature does not support this position. According to the current concept of the natural history of periodontal disease, only about one-fifth of the population, or less, is likely to have periodontitis severe enough to cause tooth loss. This view is consistent with data from this and most other studies on the reasons for tooth extraction.

Adolescent↗

Purification of rabbit bone morphogenetic protein derived from bone, dentin, and wound tissue after tooth extraction.

Bone morphogenetic protein (BMP) was extracted from bone matrix, dentin matrix, and wound tissue after tooth extraction in rabbits, and purified. These purified fractions were shown to be homogeneous by sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis (SDS-PAGE), and induced new bone in situ in 3 weeks when implanted into the calf muscles of Wistar rats. The dentin matrix-derived BMP was different from the other two types in molecular weight and the properties revealed in the process of purification. However, each tissue-derived BMP was shown to induce new bone growth in a bioassay of xenogenic implantation. For this reason, BMP is thought to have subunits with certain commonalities in different tissue.

Animals↗

Description of a clinical technique for tooth extraction in the cleft lip and palate area.

Cleft lip and palate are relatively common congenital malformations, which may require specialist paedodontic treatment. In this article, the case of a 9-year-old boy with bilateral complete cleft lip and palate is presented. He attended the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC) for routine examination, during which the presence of pre-canine supernumeraries bilaterally in the cleft area was seen. The extraction of these dental elements was justified by extensive carious lesions and because they represented a potential problem during secondary palatoplasty. The precautions needed in tooth extraction in patients with cleft lip and palate are described, together with illustrations of the clinical procedure.

Child↗

The annual frequency of root fillings, tooth extractions and pulp-related procedures in Danish adults during 1977-2003.

AIM: To investigate a hypothesized long-time decrease of endodontic treatment in a population with low caries prevalence. METHODOLOGY: A Danish nationwide database including almost all dental diagnostic, prophylactic and therapeutic procedures performed in Danish adults was available. Data on the annual frequencies of root fillings, extractions, pulpotomies, direct pulp cappings and stepwise excavations between 1977 and 2003 were analysed. Data on pulpal and periapical diagnoses were not available and on patients age and gender only from 1996. RESULTS: Between 1977 and 2003 the annual number of root filled canals increased from 268,223 to 364,867 (36%). The annual number of root filled teeth increased from 160,119 to 191,803 (20%). During the period, the annually registered patients increased by 16%. Calculated per 1000 patients, the number of root fillings showed a statistically significant increase of 17%. In root filled teeth the canal/tooth ratio increased from 1.67 to 1.96. Root fillings were frequently recorded in all age groups with the bulk of treatments performed on patients between 40 and 60 years of age. At a total population level, the rate of root fillings decreased among younger individuals and increased among older. The annual number of tooth extractions was more than halved from 656,624 in 1977 to 346,490 in 2003. Pulpotomies decreased markedly over the period and less than 10 treatments per 1000 patients were noted for pulp capping as well as stepwise excavation procedures. CONCLUSIONS: The present study failed to show a long-time decrease of endodontic treatment in a population with low caries prevalence. On the contrary, an increase of root filled canals was observed between 1977 and 2003, which was probably due to a reduction of the tooth extraction rate and an increased treatment of multi-rooted teeth.

Adult↗

Acellular dermal matrix and hydroxyapatite in prevention of ridge deformities after tooth extraction.

The aim of this study was to evaluate the role of acellular dermal matrix graft (ADMG) acting as a membrane, associated with a resorbable hydroxyapatite (RHA) in bone regeneration to prevent ridge deformities after tooth extraction. Fifteen patients who had at least 2 noncontiguous, uniradicular teeth indicated for extraction were selected. In group I, the extraction sockets were covered by ADMG alone; and in group II, the alveoli were filled with RHA before the placement of the ADMG. After 6 months, re-entry surgeries and biopsies were performed. Although ridge thickness had been preserved in both groups, the means were significantly greater (P < 0.05) for group II when compared to group I (6,8 +/- 1.26 and 5.53 +/- 1.06). The histologic analysis showed small bone formation in some samples for group II, where the presence of a highly vascularized fibrous connective tissue surrounding the particles was a common finding. Based on the results, it can be concluded that the ADMG was able to preserve ridge thickness and that the additional use of RHA favored the preservation of the ridges along with an increase in the width of keratinized tissue.

Absorbable Implants↗