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Critical period for effects of infantile experience on maturation of stress response.

Manipulated infant rats respond to cold with depletion of adrenal ascorbic acid (AAA) significantly earlier than nonmanipulated infants. The study discussed in this report examined the critical period for infantile manipulation on the depletion of AAA. It was found that infant rats manipulated immediately following birth exhibited significant AAA depletion, whereas infants manipulated later did not exhibit depletion.

Adrenal Cortex↗

Biochemical responses of rats to auditory stress.

Prolonged, intense auditory stimulation caused a marked reduction in glutathione levels in the blood of female rats. The frequency of the response was significant statistically and was related inversely to the recovery rate after auditory stimulation. An increase in adrenal weights and ascorbic acid, as well as a decrease in total adrenal cholesterol, were noted.

Animals↗