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Transfer cells: cells specialized for a special purpose.

Transfer cells are plant cells with secondary wall ingrowths. These cells are ubiquitous, occurring in all plant taxonomic groups and in algae and fungi. Transfer cells form from differentiated cells across developmental windows and in response to stress. They are considered to play a central role in nutrient distribution by facilitating high rates of transport at bottlenecks for apo-/symplasmic solute exchange. These properties are conferred by their unique structural features--an invaginated secondary wall ensheathed by an amplified area of plasma membrane enriched in a suite of solute transporters. Recent development of transfer cell experimental systems, combined with technologies to image the three-dimensional structure of wall ingrowths, is allowing identification of inductive and regulatory signals, discovery of sequential processes involved in their differentiation, and a search for transfer cell identity genes. A model of key events in differentiation of a transfer cell is presented to highlight areas for future investigation.

Biological Transport↗

Reflections on the special senses in relation to the development of affect with special emphasis on blindness.

In congenital blindness, the absence of vision can be compensated for by the utilization of the tactile and auditory senses, resulting in normal affect and ego development. Some of the major problems in the way of such compensation were noted. Adventitious blindness produces disruption of ego functions, with severe affect manifestations, notably grief and mourning reactions and actual dependency. The factors favoring successful or unsuccessful resolution of mourning and restoration of normal ego functions were indicated.

Adolescent↗

Return to special: an examination of the characteristics of patients who returned to Ashworth special hospital.

Sixteen patients were returned to Ashworth in a one-year period (five second admissions, 10 failed leave of absence and one warrant of recall) making up 31% of admissions for the year. Demographic details and reasons for return were collected. Fifty per cent of patients had a clinical diagnosis of personality disorder. Reasons for return included relapse of psychosis, persistent transgression of boundaries, aggression or threatened aggression, unsuitable placements and failure to progress towards discharge.

Adult↗

Specialization of the specialized: electrophysiological investigations in professional musicians.

Several event-related brain potential (ERP) studies examining the processing of auditory stimuli by professional musicians compared with non-musicians are reviewed. In the first study, musicians (string players) and non-musicians attended to one of two streams of auditory stimuli characterized by a specific pitch. Musicians showed a prolonged ERP attention effect, the late portion of which was more frontally distributed than was that of the non-musicians. In the second study, we investigated auditory spatial processing in conductors, pianists, and nonmusicians. Only the conductors showed behavioral selectivity of sound sources located in the peripheral auditory space. In addition, this group showed a negative/positive mismatch response for deviant stimuli occurring outside the focus of spatial attention. Finally, a group of drummers was compared to woodwind players and nonmusicians in a passive listening task. A real continuous drum sequence was manipulated so that some beats were anticipated by 80 ms. The drummers showed a mismatch response not only for the anticipated beats but also for the subsequent beats, suggesting a more complex representation of the temporal aspects stimulus sequence in this subject group. Together, these studies suggest qualitative differences of the neural correlates of auditory processing between musicians and non-musicians. Moreover, these differences appear to be shaped by the specific training of a musician.

Auditory Perception↗

Special books for special children.

Simple books written for an individual child can assist that child in coping with unusual and potentially stressful medical problems. The philosophy, techniques, and process of writing this type of book are shared, as well as examples of illustrations and text from two books written for preschool children: one with a glycogen storage problem and one requiring a hand amputation. The article serves as a guide and encouragement to others involved with the emotional care of children to consider this technique as a complement to preparation and hospital play.

Bibliotherapy↗

Flashbulb memories: special, but not so special.

This study deals with flashbulb memories associated with the assassination of the Swedish prime minister Olof Palme. A major goal of this research was to explore the consistency of such memories through comparison of the subjects' recollections on two different occasions, one year apart. The results obtained indicated that flashbulb events are accurately recalled in terms of a narrative conception of the concomitant circumstances of the event, but that the event descriptions are not consistent with respect to the specific details of these circumstances. It was concluded that the loss of information during one year contradicts the notion that flashbulb memories persist in absolute accuracy over time, as has been claimed in previous studies. Rather, these memories appear to be reconstructions based on residuals of the circumstances concomitant with the specific event (i.e., that of first hearing of the shocking news), and these memories follow the same pattern of recollection as does recollection of other autobiographical and laboratory-induced emotional events.

Adult↗

Anticoagulation in special patient populations: are special dosing considerations required?

Optimal dosing of low-molecular-weight heparin (LMWH) therapy has not yet been established for patients with morbid obesity or renal insufficiency or for pregnant women. Monitoring of anti-Xa levels appears to be helpful in guiding LMWH dosing in all of these patient groups. Use of fondaparinux in these populations has yet to be defined. Cancer patients are at particular risk of venous thromboembolism and generally require escalated and/or prolonged anticoagulation with intense monitoring of therapy.

Anticoagulants↗