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PubMed1984

Antibacterial monoclonal antibodies and the dawn of a new era in the control of infection.

Literature reports concerned with monoclonal antibodies against bacteria, or their toxins, which are pathogens for man and animals were surveyed. These antibodies have important potential uses in human and veterinary pathology and medicine. They are likely to become key elements in a fast progression toward a more complete understanding and control of infectious diseases and of toxin poisoning. A new area of bacteriology relevant to sanitary engineering is also being advanced with the help of antibacterial monoclonal antibodies. This area involves bacteria that produce the biofuel methane, along with other molecules of nutritional value, through a process which brings about the recycling of organic wastes and thereby limits or controls microbial contamination of soil and water.

Animals↗

PubMed1970

[Effects Of Irradiation With Cobalt 60 To The Development Of Ascaris Eggs In Stool]

This study was carried out in order to find out the valuable measure to kill the parasite eggs in night soil. The fresh eggs of Ascaris put into human stool were irradiated with Cobalt 60 of 200,000 to 1,000,000 rad and cultured in test tubes at 25-30 degrees C, washing with 2 % formalin solution every 24 hours. The continuous development of those eggs were observed under microscope and the proprotions of developed eggs were compared with those of control groups. The major result can be summarized as follows: 1)In general, The eggs in stool developed poorly than the eggs in saline. 2)If the eggs were irradiated with the larger dose of Cobalt 60, the proportion of developed eggs were reduced subsequently. 3)The eggs irradiated with the dose of 1,000,000 rad in saline developed in the proportion of 15.5 %, whereas irradiated with 200,000 rad 94 % developed in 4 weeks. 4)The 44.5 % of eggs in stool irradiated with 200,000 rad developed after 4 weeks, 30.5 % with 300,000 rad, 25 % with 500,000 rad and 3.5 % with 1,000,000 rad respectively. 5)The effective minimum dose of Cobalt 60 irradiation to kill the Ascaris eggs in stool was estimated 1,000,000 rad. Further examination will be required to observe the infectivity of irradiated Ascaris eggs to animals and to evaluate the effect from the standpoint of sanitary engineerings.

Journal Article↗

PubMed1999

Prevention and treatment of traveler's diarrhea.

Common pathogens in traveler's diarrhea include enterotoxigenic Escherichia coli, Campylobacter, Shigella, Salmonella, Yersinia and many other species. Viruses and protozoa are the cause in many cases. Fortunately, traveler's diarrhea can usually be avoided by carefully selecting foods and beverages. Although drug prophylaxis is now discouraged, treatment with loperamide (in the absence of dysentery) and a fluoroquinolone, such as ciprofloxacin (500 mg twice daily for one to three days), is usually safe and effective in adults with traveler's diarrhea. Trimethoprim-sulfamethoxazole and doxycycline are alternatives, but resistance increasingly limits their usefulness. Antibiotic treatment is best reserved for cases that fail to quickly respond to loperamide. Antibiotic resistance is now widespread. Nonabsorbable antibiotics, immunoprophylaxis with vaccines and biotherapeutic microbes that inhibit pathogen infection may eventually supplant antibiotic treatment. In the meantime, azithromycin and new fluoroquinolones show promise as possible replacements for the older agents. Ultimately, the best solution is improvements in sanitary engineering and the development of safe water supplies.

Anti-Infective Agents↗

PubMed2002

Public health training in Albania: long way toward a school of public health.

AIM: To assess the needs for a school of public health in Albania, where health system has been going through difficult periods of transition after the collapse of the communist regime and its "Soviet" health system in 1991. METHOD: Review of the past and current state of public health training, as well as the evolution of the main institutions involved in public health training in Albania, in view of the recent attempts undertaken to establish a school of public health. RESULTS: Up to early 1990s, public health training in Albania involved mostly physicians and was based to a great extent on sanitary engineering approach. In the mid 1990s, the activities of the Department of Public Health of the Faculty of Medicine in Tirana focused on development of comprehensive public health training program. The aim of the current 2-year training program is to train public health specialists in a new fashion, in line with current international trends in the "new" public health. However, the size and the background of the faculty of the Department of Public Health (8 members, 7 physicians) is too limited and medically oriented. Since 1969, the Institute of Hygiene and Epidemiology (later National Institute of Public Health) has been providing short-term (1-3 months) courses for hygienists, chemists, and microbiologists working at the district level. CONCLUSION: Only the establishment of a school of public health capable to train specialists according to international standards can meet the health needs of Albania.

Albania↗

PubMed2003

Research of the flow procedures in a pressure sewer system.

At the Institute of Land Reclamation, Hydrology and Sanitary Engineering of the University at Rostock the pressure and flow ratios are examined within a measuring section in the pressure dewatering system on the Darss peninsula. The objective of the research project is the knowledge upgrade about the highly unsteady hydraulic conditions in a pressure sewer system. This paper firstly presents the method and the dimensioning of pressure dewatering systems, which can be done using either the peak effluent method or the statistical method; the examination program will be explained. The examination includes pressure difference measuring with two pressure meters and flow data measuring via magnetic-inductive flow meters. Additionally the pump running times of 15 pumping stations, as well as the compressor action of the pressure pipe rinsing station are continuously and temporarily recorded and saved. Finally the measuring results which provide initial information about the pressure and flow conditions in a pressure dewatering system will be presented. The effects of the rinsing, the low pressure differences, the air cushions, the seasonal differences as well as the daily development graphs of the wastewater production are all clearly visible.

Engineering↗

PubMed1991

[Monitoring of indoor air of residential and public buildings].

The quality of the air medium of residential and public buildings has been studied; contaminants discharged from polymeric materials and contained in domestic dust have been identified. Due to a great medico-hygienic significance of this problem it is necessary, that joint studies be carried out by experts in the field of hygiene, builders, sanitary engineers, physicists and chemists with the aim of the assessment of buildings from the point of view of sources of pollution in them depending on the construction and contingent of the population. Indoor air monitoring will make it possible to develop the scientific basis of indoor air quality control.

Adult↗

PubMed1989

[Quality of water in the marine environment. The history and application of microbiology standards].

The history and application of microbiological standards to measure the quality of seawater for primary-contact recreational use and for the harvesting of shellfish are reviewed. Recent research concludes that enterococci, as indicator organisms, provide the most accurate correlation with gastrointestinal disorders attributed to swimming in contaminated waters. Accordingly, a linear relation has been established between mean enterococcus density per 100 ml and swimming associated gastrointestinal disorders per 1,000 population, and in 1984 the U.S. Environmental Protection Agency (EPA) adopted these bacteria as the primary indicator organisms for recreational waters in lieu of the indicators applied up til then, mainly total and fecal coliforms. International, national, and local microbiological standards and guidelines are presented to provide the sanitary engineer with a water quality range for the marine environment. Before adaptation of particular set of standards, local and national circumstances as well as socioeconomic factors should be carefully reviewed. Moreover, the application of quantitative relationships between health risks and the level of indicator organisms should take into account the general health and immunity conditions of the local population.

Fisheries↗

PubMed1979

[New measurements of noise from road traffic in Rome carried out during 24 hours (author's transl)].

A new series of noise measurements in 10 points of the central zone in Rome, corresponding to residential areas with commercial activity, to parks, to hospitals, and to a subway, have been carried out. Investigation has been protracted during 24 hours and each measure has lasted 20 minutes. For the survey a mobile acoustic unity of the Environmental Hygiene Laboratory, Department of Sanitary Engineering, of Istituto Superiore di Sanità has been employed. The unity is fitted with instruments for statistical analysis of noise in connection with a minicomputer. The used program has allowed to calculate L1, L10, L50, L90, standard deviation, Leq, LNP, TNI. On the basis of such measurements Leq 24, Ldn, CNEL, have been calculated. Collected data have been compared with limits of stated rules and with noise levels measured in other seven Italian towns.

Automobiles↗

PubMedDate not supplied

[Eradication or antimalaria control: return to training in malariology].

The persistent endemicity in tropical Africa, the repeated resurgences in India, in South-East Asia and in tropical America require flexible tactics adapted to the local conditions. One of the main factors of success relies on the formation in depth of the triad: the epidemiologist, the medical entomologist and the sanitary engineer, by means of an up to date training of malariology.

Humans↗

PubMed1998

Eradication, control or neither? Hookworm vs malaria strategies and Rockefeller Public Health in Mexico.

Malaria's epidemiological importance in Mexico greatly exceeded that of hookworm, but the Rockefeller Foundation (RF) paid far more attention to hookworm. Although the RF collaborated with malaria campaigns around the world, malaria was only incidental to the RF's activities in Mexico. The hookworm campaign, on the other hand, involved the RF at every stage, from conceptualization and design to financing, hiring, and day-to-day administration. This paper seeks to understand why the RF's involvement in Mexico differed for the two diseases and what the organizational, political, and health implications were for these divergent approaches. Beginning in the mid 1920s the Mexican government developed a modest anti-larval service, periodically draining and filling ditches and swamps, dusting Paris green, petrolizing stagnant water, and administering quinine. Following the RF's 1927 shift towards scientific investigation, it began to sponsor small-scale malaria research, collecting climatological, entomological, epidemiological, and clinical information. The Mexican government eagerly petitioned the RF to join a national effort, but it was reluctant to become involved. A National Malaria Campaign was established in 1935 under President Lázaro Cárdenas to coordinate education, sanitary engineering, and treatment. The popular Campaign followed RF strategies even without its direct participation. Meanwhile, the RF avidly pursued modest malaria research in Mexico, funding U.S. investigators to conduct experiments on pesticides, mosquito-trapping, and controversially, watering methods for rice. These efforts culminated in the world's first field trial of DDT against louse-borne typhus and later as a residual spray for malaria. In the end the RF used Mexico as a convenient locale for scientific research that had global implications but only an incidental relationship to Mexico's own Malaria Campaign. Likewise, the RF's much more active hookworm program was more a means than an end, leading not to eradication of the disease, but to Mexico's commitment to modern public health organization and methods.

Animals↗

PubMed1986