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[Pathogen spectrum and resistance status of exclusively anaerobic odontogenic infections].

Out of 440 dentogenic pyogenic infections, 171 exclusively caused by anaerobes were investigated to understand the importance of anaerobic bacteria in dental pyogenic processes better. Grampositive anaerobic bacteria dominated. The predominant grampositive isolates in monoinfections were Peptostreptococci and in the case of mixed infections, strains of the genus Eubacterium. Strains of Prevotella and Porphyromonas dominated the gramnegative anaerobic spectra. The resistance to penicillin was very low. Altogether, only one strain of Prevotella oris and one strain of Prevotella oralis showed resistance to penicillin.

Bacteria, Anaerobic↗

Primary intraosseous carcinoma of the jaws. Three new cases and a review of the literature.

Three new cases of primary intraosseous carcinoma are presented. The clinical features of these cancers often mimics odontogenic cysts, dental abscesses or periodontal disease; all benign dental conditions. This may delay the diagnosis and probably accounts for the poor prognosis associated with these tumours of 30-40% 5-year survival. A total of 24 cases of primary intraosseous carcinomas have been analysed, which includes reports collected from the literature and the three new cases presented in this paper.

Aged↗

Bacteria in the mouth.

There are many infectious agents found within the oral cavity. Bacteria form an important group of micro-organisms found in both healthy and diseased mouths. The current article will discuss those bacteria resident within the mouth and review the oral diseases with which they are associated.

Actinomycosis, Cervicofacial↗

[Odontogenic soft tissue abscesses in the maxillofacial region. An analysis of 1386 cases from 1957--1976 at the Northwest-German Dental Clinic in Hamburg].

Between 1957 and 1976, 1386 patients with odontogenous abscesses in the area of the mouth, jaw, and face were treated on an in-patient basis at the Hospital for Jaw Surgery (Nordwestdeutschen) in Hamburg. The catamneses of these patients were evaluated noting the localization and frequency of each abscess, the age and sex distribution of the patients, and the possible teeth responsible for the abscess. Any pathogens demonstrated were carefully recorded. The degree of sensitivity and/or resistance of the various groups of pathogens were also included in the study, particularly streptococcus and staphylococcus. Uncritical and undifferentiated administration of antibiotic therapy for pyogenic inflammations in the area of the mouth, jaw, and face is not to be recommended.

Ampicillin↗

[Microbial and resistance spectrum of jaw infections].

According to this investigation, antibiotic treatment of odontogenous abcesses should be directed primarily against streptococcus and staphylococcus, even if gram-negative pathogens have apparently increased. The response on the part of streptococcus to antibiotics has not changed essentially during the last five years. Staphylococcus however has developed a resistance to penicillin and ampicillin.

Anti-Bacterial Agents↗

[Spectrum of pathogens in odontogenous abscesses in the patients of the Tübingen Department of Maxillofacial Surgery].

Bacteriological examination and evaluation of 475 smears of pus taken from odontogenous abcesses showed that the spectrum of pathogens is extremely broad. Chemotherapy therefore should not be started before the pathogen has been identified and an antibiogram has been made due to possible resistance on the part of the microorganisms. Clindamycin may be used for "blind treatment" until the bacteriologic findings are available because it is effective against streptococcus and staphylococcus as well as gram-negative asporous anaerobes. The risk of the possible ineffectiveness of clindamycin against gramnegative anaerobes however must be taken. Clindamycin and gentamicin together may be helpful in life-threatening situations because the combination covers an extremely broad spectrum of possible pathogens.

Clindamycin↗

[Odontogenic soft tissue infections (localization, treatment and course in 1002 cases)].

Between 1965 and 1974, 1002 patients were treated on an in-patient basis for odontogenous soft-tissue infections. Abcesses were observed in 960 patients; inflammatory infiltrate, in 39 patients; a phlegmon, in 3 patients. The relation of male to female patients was 56:44. The 21- to 30-year-old age group was most frequently affected. Antibiotic therapy was administered over a period of weeks prior to admission in 87% of the patients. Operative procedures prior to admission had been performed on only a few patients.

Adult↗

[Problems of bacteriologic diagnosis and aimed antibiotic therapy in pyogenic maxillofacial infections].

Bacteriologic analysis of pathogens from pyogenic infections of the jaw in 71 patients revealed that bacteria normally found in the buccal cavity predominated in 86% of the specimens. Considering the fact that no pathogens could be identified in 7% of the specimens, this then means that pathogens were only found in 7% of the specimens. Six to 12 strains were usually isolated in the mixed bacteria population of the buccal cavity. A total of 430 strains of bacteria were cultured and tested for their response to 20 common antibiotic preparations. We were able to confirm the high effectiveness of penicillin and/or broad spectrum penicillin 92% of the cases (8600 determinations of resistance). Tetracycline was effective in 89% of the cases; trimethoprim sulfamethoxazole, in 83%. The effectiveness of newer, more expensive, antibiotic preparations was not significantly better than that of pencillin. Administration of such antibiotic preparations therefore should be limited to problematic pathogens.

Anti-Bacterial Agents↗

[Bacteriology of odontogenic abscesses].

The primary bacteria strains and their sensitivity to antibiotic drugs were examined in 329 patients with extraoral split abscess who were treated on an in-patient basis. Combination therapy using various antibiotics together with gentamycin was recommended. An antibiogram however should be completed if antibiotic therapy is to be purposeful.

Anti-Bacterial Agents↗