Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Paris”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

Plaster of Paris and hair cell morphology. A scanning electron microscopic study of an alternative implant material for ear surgery.

Many techniques have been proposed for reconstruction of the posterior canal wall and/or obliteration of the mastoid bowl after radical mastoidectomy. The variety of materials that have been used, biological as well as foreign materials of different kinds, indicates that the ideal solution has yet to be found. Plaster of Paris, a biocompatible, degradable ceramic material prepared from CaSO4, may have an osteogenic property and become an alternative implant material for ear surgery. However, its possible ototoxicity has not been studied previously. Plaster was implanted in the tympanic cavity of guinea pigs. On investigation in the scanning electron microscope after 4.5 to 8 months, no toxic damage to the hair cell morphology was observed. Thus, from an ototoxic point of view, plaster of Paris would seem suitable for use as an implant material in ear surgery. Studies concerning the possible osteogenic property of plaster of Paris and its clinical application in human ear surgery are in progress.

Animals↗
PubMed1986

Hexcelite versus plaster of Paris: a controlled trial of the below-knee walking cast.

Hexcelite and plaster of Paris below-knee walking casts were compared in a controlled clinical trial, involving 82 patients. Fewer bandage complications, problems and better comfort was found with Hexcelite compared to plaster of Paris (P less than 0.05). If all costs relating to materials, transportation, complications and extra visits due to these, were taken into account, plaster of Paris was found more expensive than Hexcelite. Based on the above an increased use of Hexcelite is recommended.

Adolescent↗
PubMed2005

Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft.

Paris polyphylla is a traditional Chinese Medical herb that has been used in treating cancer for thousands of year. Without studies on the anticancer effects of Paris polyphylla being initiated before, we have first studied the component of Paris polyphylla and have spotted out a steroidal saponin, polyphyllin D. As long as the chemical structure and the improved synthesis of polyphyllin D were ascertained, both in vitro to in vivo studies were performed. It was found that treatment of MCF-7 and MDA-MB-231 cells with polyphyllin D resulted in the inhibition of viability and induction of apoptosis in a dose-dependent manner, with an IC50 of 5 microM and 2.5 microM, respectively, after 48 hours of incubations. Apoptosis of MCF-7 and MDA-MB-231 cells by polyphyllin D was evidenced by the occurrence of DNA fragmentation, formation of a hypodiploid peak in the cell cycle analysis, phosphatidyl-serine externalization and a late loss of membrane integrity. Mechanistically, polyphyllin D dissipates the mitochondrial membrane potential, induces a downregulation of anti-apoptotic Bcl-2 expression and an up-regulation of pro-apoptotic Bax expression, and activates caspase-9. These results suggest that polyphyllin D elicits apoptosis through mitochondria dysfunction. In vivo study demonstrated that daily administration of polyphyllin D (2.73 mg/kg body weight) through intravenous injection for ten days in nude mice bearing MCF-7 cells effectively reduced tumor growth for 50% in terms of tumor weight and size, given no significant toxicity in heart and liver to the host. All these findings provide novel insights that polyphyllin D could serve as a candidate in breast cancer treatment.

Animals↗
PubMed2000

Familial thrombophilia associated with fibrinogen paris V: Dusart syndrome.

We report on a family with a history of venous thromboembolism associated with fibrinogen Paris V (fibrinogen Aalpha-Arg554-->Cys). Ten members experienced thrombotic events, including 4 with fatal pulmonary emboli. Pulmonary embolism was the presenting feature in 4. Those with the mutation and a history of thrombosis had somewhat higher fibrinogen concentrations than those with the mutation and no thrombosis (294 +/- 70 mg/dL vs 217 +/- 37 mg/dL, respectively). The Paris V mutation consistently caused a prolongation of the reptilase time, and fibrin clots containing the abnormal fibrinogen were more translucent than normal clots. Given the early onset of symptoms and the initial presentation with pulmonary embolism in some family members, it was justifiable to offer prophylactic anticoagulation with warfarin to carriers of the mutation. Fibrinogen Paris V has now been reported in 4 apparently unrelated families, indicating that it is a relatively common cause of dysfibrinogenemia-associated thrombosis.

Adolescent↗
PubMed1999

[Medical humanism at the Faculté de médecine de Paris: one hundred years of history (1795-1898)].

During the nineteenth century, tumultuous relationships existed between the public authorities, the Paris Medical Faculty, its students and teachers, the medical and the popular press. These agitated debates concerned the value of teaching history in medical studies. This paper aims to follow the main steps of these debates through various texts: the new plan for the structure of Medicine in France (1790); the creation (1795), suppression (1822) and restoration (1870) of the Paris chair of the History of Medicine; Guerin's report (1830) concerning the a new reorganization of the Paris Medical Faculty; Dr. Dezeimeris's petitions (1837) addressed to the French Minister of State for Education. These debates remain topical and instructive.

Faculty, Medical↗
PubMed1996

[The bicentenary of the founding of the Free Society of Pharmacists of Paris (20 March 1796)].

From 1777 to 1796, the Paris Pharmacists guild was deeply modified. In 1777, a Royal Declaration created the College of pharmacy which escaped abolition of all guilds, in 1791, thanks to Eustache Livré, a member of the Constituent Assembly. The College's members, with the help of Antoine Fourcroy, founded the Free Paris Pharmacists Society and a Free School of Pharmacy, in 1796. In 1803, the School of Pharmacy and the Paris Pharmacy Society replaced these two establishments.

France↗
PubMed1999

[Paris hospitals budget in 1848, from charity to care].

Paris hospitals budget is, in the year 1848, the last before the "Assistance Publique" foundation. 1848 is characterized by important political troubles in Paris and an increased hospital activity. Nevertheless, the budget could suggest a certain wealth. Receipts are mainly based on financial funding and real estate incomes. Expenses are, for one half, linked to patients considered as hosts: food, heating, cleaning, etc. Staff expenses are moderate (12%). Various expenditures are in the same range within the different hospitals. It is interesting to outline the fact that drug expenses have the same importance than 150 years later: 4%. This feature is only an average insofar as general hospital spend about 10% of their budget in drugs as long-term care hospitals spend 1%. This disparity is clearly the proof of an increasing medicalization of Paris hospitals in the middle of the 19th century.

France↗
PubMed1989

[The history of training at the Société psychoanalytique de Paris].

As from its creation in 1926, the Société psychanalytique de Paris took charge of organizing the transmission of psychoanalysis by founding a first Institut whose activities came to an end in 1940. As from the founding of a second Institut de Psychanalyse by S. Nacht in 1954, the training of psychoanalysts was to follow an orientation that was particular to the Société psychanalytique de Paris. Specific conflicts pertaining to the question of psychoanalytic training, the scisson of the Société psychanalytique de Paris and the evolution of the psychoanalytic movement in France were determining factors in the evolution of training at the Institut. The selection of candidates, didactic analysis, supervision, teaching and details concerning the training program are presented in their evolution.

Education↗
PubMed1994

[The key function of the military hospital at Versaille to the army responsible for winning back Paris during the insurrection of the commune (March-May 1871)].

The military Hospital of Versailles standing near the seat of the Government and the Assemblies played an important role in the organization of the sanitary services of the Versailles army. Hippolyte Larrey, chief physician of the army decided in agreement with Thiers, head of the government that the military hospital will primarily receive all the wounded soldiers evacuated from the front lines and all the patients from the various regiments of the Versailles army. To satisfy the numerous hospitalisations, annexes were opened in Versailles, the hospital capacity being extended to 2600 beds. In proportion of the troops progression towards Paris, the evacuation plan of the wounded soldiers will be modified the delays of evacuation towards Versailles becoming too long, by the creation of campaign hospitals and by sending wounded soldiers to the military hospitals of Paris (Val-de-Grâce and Gros Caillou) and to some ambulances established during the siege of Paris.

France↗
PubMed1994

[The symbol of the three kingdoms in nature and the pharmaceutical tokens of Paris].

A token from the Municipal Series in Paris (Paris, Bibliothèque Nationale, Cabinet des Médailles) discovered by C. Aurensan bears on the obverse the arms of Paris and on the reverse the symbol of the three kingdoms in nature with its legend. This reverse is identical to those tokens made for Parisian apothecaries in 1628, 1629 and 1632. Unfortunately the date which it bears is poorly engraved and one cannot determine whether it reads 1619 or 1629. Several arguments militate in favor of 1619.

Emblems and Insignia↗
PubMed1995

[Tokens of deans of the Faculty of Medicine of Paris which evoke pharmaceutical recollections].

Three deans of the former Faculty of Medicine of Paris had tokens minted which referred to apothecaries: E.-F. Geoffroy, master apothecary of Paris before becoming a doctor of medicine; H.-T. Baron, senior, who succeeded in publishing the Paris Pharmacopoeia of 1732; P.-J.-B. Chomel, who cultivated "everyday plants", the object of his work, on land on the rue de l'Arbalète close by the "Jardin des Apothicaires". The author explains and reproduces the tokens.

France↗
PubMed2001

[Interuniversity Medical Library in Paris (BIUM) Collection of the Polish theses for doctor degrees].

The study consist of two parts. The first refers to the history and the present of Medical Library in Paris - one of the richest European medical book libraries, containing among others collection gathered by Medical Faculty and the Royal Medical Society since 1391. An abridged description of its edifice in the University of René Descartes, interior decorations of its main hall and opened quarters, as well as exhibits of the Museum of Medicine History is given. Author rises merits of professor Pierre Süe - surgeon and librarian - rendered by rescue of the library dismembered during the revolution of 1789. Here we shall find references of the most valuable incunabula and rare prints of the collection, distinctive for particular periods of progress in medicine and printing art. The second part of study contains information about unique collection of doctor theses presented in Medical Faculty since 1539 to 1778, and dissertations from Montpellier, Strasbourg and universities abroad - up to 1778. Particularly important seem to be titles of 32 theses prepared by the Polish authors awarding doctor degrees in Paris in the years 1890-1900 retrieved by the author, as completing in this field the Stanislas Konopka's Polish Medical Bibliography of XIX century (vol. IX, article: Doctor Theses - Paris).

Academic Dissertations as Topic↗
PubMed2003

[The Boulducs' dynasty, apothecaries in Paris in XVIIth and XVIIIth centuries: Jean François Boulduc (February 20, 1728 - August 18, 1769)].

Jean-François Boulduc was Gilles-François Boulduc's illegitimate child. At his death his property inventory revealed numerous documents (baptism certificate, ill, etc.) that allowed us to specify his professional activity. He practised galenic and chemical pharmacy trade rue des Boucheries in Paris and went into partnership with two apothecaries Claude Pia and Michel Depène successively. First apothecary of King Louis XV, he provided the Court in Versailles and Marley with medicines that he prepared in his pharmacy in Paris or in a laboratory in his house in Marly-le-Roi. He died in Paris on August 18, 1769 without progeny.

France↗
PubMed2004

[Studies on distribution of paris and annual growing characters of some species on Mountain E' mei].

The research of distribution and habitat of Paris on Mountain E' mei showed that: (1) there were 8 species and 3 varieties of Paris on Mt. E' mei, most of them distributed from alti. 1000m to 1400m in humid and fertile, neutral or acid soil under the evergreen broad-leaved forests, bamboo forests and shrub forests. (2) only Paris bashanensis distributed at higher altitude about 1800 approximately 2800 m; (3) the growing time of P. polyphylla var. chinensis and other two species planted at the lower E' mei mountain area, was later and shorter than those plantd at Kunming; (4) the whole rhizome or with terminal bud as the planting material had a high survival rate and grew fast.

Altitude↗
PubMed2005

[Screening and identification of steroidal saponins-producing endophytes from Paris polyphylla var. chinensis Franch].

Two endophytic strains SS01 and SS02 with the potential for producing steroidal saponins were isolated from the underground stems of Paris polyphylla var. chinensis Franch. The TLC comparison indicated that there are 3 sports with similar R(f) between the metabolites of SS01 and the saponins of Paris polyphylla var. chinensis Franch. And there are 2 sports with similar R(f) between the metabolites of SS02 and the saponins of Paris polyphylla var. chinensis The and that biochemical SS01 Franch. characteristics of morphology, physiological belonged showed to Enterobacteriaceae and SS02 belonged to Bacillus sp.. The 16S rDNA of SS01 and SS02 were PCR and sequenced. The accessions of GenBank are AY842143 and AY842144, respectively. The two 16S rDNA phylogenetic trees were constructed by comparing with the published 16S rDNA sequences of the relative bacteria species. In the first phylogenetic tree SS01 and Cedecea davisae DSM 4568 was the closest relative with 98.9% sequence similarity, and in the second phylogenetic tree SS02 and Paenibacillus daejeonensis was the closest relative with 97.7% sequence similarity. According to the phylogenetic analysis they were identified as Cedecea davisae SS01 and Paenibacillus daejeonensis SS02, respectively.

Bacillaceae↗
PubMed1995

[Tuberculosis in Africans hospitalized in Paris. Impact of infection by the human immunodeficiency virus].

OBJECTIVES: Human immunodeficiency virus (HIV) infection has greatly modified the epidemiology and clinical course of tuberculosis. The aim of this study was to analyze the characteristics of tuberculosis in African patients hospitalized in Paris by comparing clinical features in patients with and without HIV infection. METHODS: Hospital records of 71 patients from Africa hospitalized between 1989 and 1992 in Paris with a certain or probable diagnosis of tuberculosis were studied retrospectively. RESULTS: There were 30 patients (42%) with HIV infection. In 12 of them (40%) HIV positivity was discovered at diagnosis of tuberculosis. Age, sex, and duration of residence in France before diagnosis were similar between HIV+ and HIV- patients. Pulmonary tuberculosis was found in 23 patients and extrapulmonary forms (mainly lymph node involvement) were seen in 34; both in 14 patients. There was no difference in localization between HIV+ and HIV- patients except for disseminated tuberculosis which was more frequent in HIV+ patients. Skin reactions to tuberculin were positive in 76% and 97% of the HIV- and HIV+ patients respectively (p < 0.02). Drug resistance was observed in 8 patients (6 HIV+): streptomycin (n = 6), pyrazinamide (n = 2), isoniazide (n = 2), ethambutol (n = 1) and rifampicin (n = 1). Drug therapy was successful in controlling the initial manifestations of tuberculosis in both HIV+ and HIV- patients. CONCLUSION: Extrapulmonary forms of tuberculosis, especially lymph node infection was more frequent in Africans hospitalized in Paris, whether the patients were HIV positive or negative. HIV infection was associated with disseminated tuberculosis, non-excavated pulmonary tuberculosis and undesirable side effects of antituberculosis drugs.

AIDS-Related Opportunistic Infections↗
PubMed1997

[Clinicopathological study of the fundic varices--blood vessel structure in gastric paries].

The structures of blood vessels in 18 cases with fundic varices (FV) were studied by injecting gelatin-added barium into varicose vessels of resected specimens. There was no direct connection outside the gastric paries between the inflow path and the outflow path of FV. Just outside the gastric paries, the outflow path was not branched. Blood vessels which formed FV were found in the submucous layer, but not in the lamina propria mucosae. FVs were classified into two types according to the ramification form of FV-forming vessels inside the gastric paries: Type I, with only a few rami observed, and type II, with many rami recognized. In this study, type I FV accounted for about 78%, and type II FV about 22% of 18 cases observed. These findings deserve full consideration in the diagnosis and treatment of FV.

Adult↗
PubMed2002

Epidemiology of invasive aspergillosis in France: a six-year multicentric survey in the Greater Paris area.

Invasive aspergillosis is the most prevalent mould infection. An epidemiological surveillance network was set up in 18 teaching hospitals in Paris and the Greater Paris area. Prospective surveillance was conducted between 1994 and 1999. Between 1994 and 1997 cases were categorized as proven or probable aspergillosis and then the European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria were used. The authors analysed 621 cases (115 proven, 506 probable). No seasonal variation was found. Haematological disorders (73%) including stem-cell transplantation (36%), solid-organ transplantations (10%) and AIDS (9%) were the main underlying conditions. The crude mortality was 63%. Incidence of IA was 8% (CI(95): 6.5-9.5) in acute myelocytic leukaemia and 6.3% (CI(95): 4.3-8.3) in acute lymphocytic leukaemia. Incidence was 12.8% (CI(95): 10.8-14.8) following allogeneic stem-cell transplantation and 1.1% (CI(95): 0.7-1.5) following autologous stem-cell transplantation. In solid-organ recipients incidence ranged from 11% following heart-lung transplantation and small bowel to 0.4% following kidney transplantation. Incidence in HIV infected patients ranged from 0.02 to 0.13% per annum. This large series confirmed that patients with haematologic disorders and transplantations are the most at risk for IA.

Adolescent↗