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[Syphilitic arthro-osteitis].

We report a black female with past history of sexual promiscuity who developed arthroosteitis of clavicula and sternoclavicular joint and cranial osteitis during secondary syphilis. Spirochaeta were identified in the material from osteoarticular biopsy. The patient was treated with benzathine penicillin, 2,400,000 U weekly for three weeks. There was a complete clinical recovery. We emphasize the uncommon occurrence of osteoarticular involvement in secondary syphilis and the exceptional character, according to the literature, of the finding of spirochaeta in the biopsy material. We discuss the differential diagnosis and we review the literature on secondary syphilis. We suggest that syphilis should be considered in the differential diagnosis of any acute arthritis or osteitis, particularly when the involved joint is the sternoclavicular and the patient is sexually promiscuous.

Adult↗

[Observations on post-traumatic osteitis].

The following study reports the frequency, the promoting factors, the therapy and her results of the 32 patients with posttraumatic osteitis we treated between 1984 and 1986 in the Surgical University Clinic Tübingen. Most of the primary injuries were caused by traffic-accidents; especially dangerous were those with motor-bikes, which led frequently via open fractures of the shank to osteitis. We saw the highest infection-rates after plate-osteosyntheses. The infects became obvious in most cases either about one month after the accident or a year later coinciding with the increased use of the limb. The most frequent bacterium was Staph. aureus both in the mono-infections and in the mixed-infections forming a third of the group. We always performed an operative therapy with the intention to stabilize the bone and to clean the infection-site. The strict performance of this management led to infect-suppression in all cases with the need of only one amputation.

Adult↗

[The results of radical-rehabilitative surgical treatment in tuberculous osteitis of the hip joint in children].

Radical restorative surgery is an operation of choice in treatment of tuberculous osteitis of the hip joint in children of all age groups irrespective of the destructive process localization and duration. The early surgical treatment provided recovery from tuberculous osteitis in 100 per cent of the patients and proper development of the operated hip joint in 90 per cent of the patients.

Adolescent↗

[Acne-pustulosis-hyperostosis-osteitis syndrome. Results of a national survey. 85 cases].

The authors report the data collected by a national investigation organized by the French Society of Rheumatology, concerning the osteo-articular manifestations of severe acne, palmo-plantar pustulosis and primary thoracic and peripheral hyperostosis. This investigation collected 85 case-reports including 13 severe acne, 44 PPP and 28 hyperostosis without the dermatitis mentioned above. From this investigation, it appears that dermatological and osseous pictures described under various denominations, present common characteristics and transition forms justifying their common study under the acronym SAPHO (Syndrome Acne-Pustulosis-Hyperostosis-Osteitis). The bony involvement, especially anterior thoracic, but also vertebral and even peripheral seems to be the common denominator between these diseases. It realizes a true rheumatoid inflammatory osteitis, osseous counterpart of synovial and cartilagenous affections in inflammatory rheumatoid diseases. This group has rather loose connections with common psoriasis and slightly more definite relationships with primary ankylosing spondylarthritis. These clinical and immunogenetic connections occur also through bony involvement.

Acne Vulgaris↗

Condensing osteitis of the clavicle: case report and review of the literature.

Osteitis condensans of the clavicle is a benign, often painful disorder of unknown etiology manifested by bony sclerosis of the clavicular head with an uninvolved sternoclavicular joint. The case presented demonstrates the characteristic scintigraphic findings of osteitis condensans of the clavicle. A review of the published pathologically proven cases reveals this disorder to have distinctive clinical and radiological features that allow differentiation from infection, neoplasia, and arthritides in most instances. The frequent observation, as in this case, of devitalized bone and marrow fibrosis with remodeling of cancellous bone suggests that osteonecrosis may play an important role in the pathogenesis of this disorder.

Adult↗

Condensing osteitis of the clavicle. A review of the literature and report of three cases.

Condensing osteitis of the clavicle is a rare and benign idiopathic entity that is probably degenerative or mechanical in etiology. It is usually seen in women of late child-bearing age as a variably painful and tender swelling over the medial end of the clavicle. Radiographs show sclerosis and slight expansion of the medial one-third of the clavicle. Although malignant tumor of bone must be considered in the differential diagnosis of a disease that has such radiographic findings, numerous and expensive screening tests for a presumed primary malignant lesion are not recommended for most patients. It is recommended, however, that an excisional or (preferably) incisional biopsy be performed in all patients unless pain is insignificant and the clinical presentation strongly supports the diagnosis of condensing osteitis. Many patients who have slight pain do not need treatment. Anti-inflammatory medications are variably effective. Patients in whom the lesion is refractory respond well to excision of the medial one-third of the clavicle.

Adult↗

[Osteitis due to anaerobic Corynebacteria in children. Apropos of 4 cases].

The authors have seen four instances in children of osteitis due to a mycobacterium. The disease was subacute and situated in the tibia, the lumbar spine, the talus and the femur. In two cases the diagnosis was eventually mistakenly oriented towards tuberculosis or a malignant tumour. The correct diagnosis was obtained after a bone biopsy which demonstrated a granulomatous osteitis. In such cases there is an indication for a full biopsy and bacteriological examination with culture in aerobic and anaerobic media. Treatment based on pristinamycin resulted in healing.

Bacterial Infections↗

[The treatment of chronic osteitis using genta-PMMA chains].

Disulphine blue vital staining, cancellous bone grafts to Papineau and local implantation of genta-PMMA-chains are new procedures in treatment of chronic osteitis. Between May 1978 and December 1984 a total of 24 patients underwent surgery for osteitis. The mean follow up was 25 months (range 17 m. and 35 m.). Good results were obtained in 70.8% (17/24).

Adolescent↗

[Mandibular osteitis and tertiary syphilis].

The authors report the case of a 65 years old man, who suffered from an osteitis, involving the mandible. Within a few months, and despite of a well established treatment, sequestration occurred following a pathologic fracture. No specific germ was encountered after several laboratory examinations. The discovery of a primary syphilis forty years ago, confrontation of clinic and paraclinic data, suggested the actual osteitis could be a complication of tertiary syphilis. A specific treatment was started, and the situation improved progressively. After five months of treatment, mandibular reconstruction was decided. Diagnostic arguments are discussed, and the case is compared with those, not numerous, reported in the literature.

Aged↗

[Sequestral osteitis with fracture of the mandibular angle occurring secondarily to the extraction of a wisdom tooth. Apropos of a case].

The authors report on a case of sequestrated osteitis complicated by a fracture of the angle of the mandible, following the avulsion of a wisdom tooth in a 20 year old man. The treatment consisted of an intermaxillary fixation of the mandibular arche lasting 40 days accompanied by wide-spectrum antibiotic therapy for 15 days, until such time as the ESR and blood count values returned to normal. In three months resorbtion of the sequestrated necrotic bone and disappearance of the osteitic cavity was noted, all of which was indicative of a satisfactory result. From the aetiological point of view it was possible to confirm by way of a routine X-ray taken 5 days after the extraction that the lesions had developed of their own accord, thus eliminating surgery and trauma as causes. The problem of what causes maxillary osteitis remains, and in particular, the role played by local anaesthetics containing adrenaline.

Adult↗

Osteitis pubis: an unusual complication of herniorrhaphy.

Osteitis pubis is a well known complication of urologic and gynecologic procedures but its association with herniorrhaphy is poorly documented in the literature. A 55-year-old man underwent herniorrhaphy for a direct inguinal hernia, followed in 48 hours by herniorrhaphy for a femoral hernia. One week later he complained of pain in the pubic area and over the ischial tuberosities, had intermittent fever and an elevated erythrocyte sedimentation rate. Roentgenograms showed changes typical of osteitis pubis with widening of the symphysis pubis, loss of definition of the adjacent cortical surfaces and involvement of the ischial tuberosities. There ws no evidence of infection in the urinary tract or elsewhere. The patient was treated with indomethacin and showed clinical and radiologic improvement over the next 6 months. It is possible that in this case two operative interventions involving structures inserting into the pubic bones and performed within a short time of each other exposed this patient to an unusual complication.

Hernia, Inguinal↗

Concentrations of oxytetracycline, tetracycline and doxycycline in mandibular osteitis.

Treatment of osteitis in the mandible after surgery is still a clinical problem. Levels of three tetracyclines--doxycycline, oxytetracycline and tetracycline--were measured in serum and dental alveolar serum in 30 patients undergoing oral surgery. The serum concentrations were higher than the dental alveolar serum concentrations in all patients. The maximal concentration in the alveolar serum for doxycycline was between 3.0 and 3.5 mug/ml while the corresponding values for oxytetracycline and tetracycline were between 1.0 and 2.0 mug/ml. When the dental alveolar serum concentrations of the various tetracycline analogues were related to their range of inhibitory concentrations for microorganisms isolated from mandibular osteitis, it was found that each drug reached levels sufficient to inhibit most but not all strains.

Administration, Oral↗

[Osteitis condensans ilii].

OBJECTIVE: The description of a case of osteitis condensans ilii. DESIGN: Descriptive. SETTING: Base health area. PATIENTS AND OTHER PARTICIPANTS: A 24-year-old puerperal woman. INTERVENTIONS: Analgesic treatment. MEASUREMENTS AND MAIN RESULTS: We were presented with the history of a woman with low lumbar pain of a mechanical character, after a dystocial birth two months previously. The radiology showed a triangular bony condensation on the edge of the sacroiliac joints. CONCLUSIONS: Osteitis condensans ilii is a benign structure, almost only ever found in women who have borne children. Its presentation is asymptomatic or nonspecific (low lumbalgia). Its very specific radiological image needs to be distinguished carefully in order to avoid diagnostical confusion with ankylosing spondylitis and other causes of sacroiliitis.

Adult↗

Osteitis condensans of the clavicle: does fibrocartilage play a role? A report of two cases with spontaneous clinical and roentgenographic resolution.

Two cases of osteitis condensans of the medial clavicle with an unusual course toward spontaneous resolution of clinical and roentgenographic manifestations are reported. The relevant literature is reviewed. A pathogenic hypothesis for condensing osteitis of the clavicle, ilium, and pubis is suggested. At all these sites, the sclerosis occurs in bone overlaid by fibrocartilage. In contrast, joint aspects spared by the sclerosis are covered with hyaline cartilage. We report data documenting this fact at the sternoclavicular joint.

Adult↗

[Inguinal hernia under laparoscopy. Pubic osteitis].

Osteitis pubis is a well known complication of urologic procedures but its association with herniorraphy is poorly documented in the literature. We report a case of osteitis pubis after coelioscopic cure of hernia. It is too early to know its frequency in coelioscopic repair. The choice of this technic might be discussed if it appears that with this technic the frequency is higher than in traditional surgery where it was rare.

Adrenal Cortex Hormones↗

Osteitis caused by bacille Calmette-Guérin vaccination: an emergent problem in Chile?

SETTING: Osteitis caused by bacille Calmette-Guérin (BCGOST) vaccination has not been described in Latin American countries. OBJECTIVE: To evaluate the incidence, clinical features and prognosis of patients with BCGOST in one of the most populated areas of Santiago, Chile. DESIGN: A retrospective analysis of medical records kept over twenty years (1976-1995). RESULTS: In ten children (four in the last five years), diagnostic criteria of BCGOST were fulfilled. Six were boys, the mean age was 11 months (range 6.5-21), symptoms were present with a mean of 31 days (range 15-60) before diagnosis and the sites of predilection of osteitis were the lower extremity (8/10 cases). Culture was positive in one case, and nine patients had typical histopathological lesions (two with acid-fast bacilli). All had normal chest X-ray. Mantoux testing was performed in four cases (mean 21.5 mm, range 16-28). None of the ten patients had a history of underlying immunodeficiency. In this area BCG coverage was 90.2 +/- 9.7% of all newborn infants, and the annual risk of tuberculosis infection was 24.6/100,000 population per year. CONCLUSION: Our study demonstrated an estimated incidence for BCGOST in this area of 3.2/100,000 vaccinated newborns. Based on the epidemiological situation of tuberculosis in Chile (29.5/100,000), universal BCG vaccination in newborns should be encouraged.

Age Distribution↗

Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a brief review of a rare condition.

Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis (SAPHO) syndrome is an osteoarticular-skin syndrome characterised by sterile inflammatory arthro-osteitis of the anterior chest wall. It is associated with various skin conditions including palmoplantar pustulosis, severe acnes and pustular psoriasis. A link between SAPHO syndrome and seronegative spondyloarthropathies has been suggested over the last 10 years. SAPHO syndrome mainly affects young and middle-aged adults. Treatment of SAPHO syndrome remains empirical as the underlying aetiopathogenesis is unclear.

Acne Vulgaris↗