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PubMed1990

Guidelines for the use of zidovudine for post-exposure prophylaxis after needlestick injuries in health care settings.

A protocol for the management of health care personnel after exposure to the human immunodeficiency virus in the workplace is set out. The use of zidovudine is advocated, although sufficient evidence for its use in these circumstances is lacking. Recommendations for zidovudine chemoprophylaxis, including dosage regimens, duration of therapy, and laboratory monitoring tests, are given. The need to avoid occupational needlestick injuries is stressed.

Acquired Immunodeficiency Syndrome↗

PubMed1988

Needlestick injuries: how can we teach people better about risk assessment?

At work people run some small risk of death or injury which is directly attributable to their occupation. In biomedical sciences the accidental puncture of the skin by hypodermic needles, other instruments or broken glass has long been regarded as an occupational hazard and there is increasing concern that staff could become infected with a range of micro-organisms, including hepatitis B and the Human Immunodeficiency Virus (HIV). Needlestick injuries should be preventable if staff are trained effectively and take care about disposal of used syringes and needles. Staff at risk must be offered pre-exposure vaccination for hepatitis B and resources must be provided for special training. Fundamental changes may be required in methods and equipment and a number of new ways of targeting groups of health care staff with information are discussed.

Accidents, Occupational↗

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