Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Necator”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

Mutagens in larger fungi. II. The mutagenicity of commercial pickled Lactarius necator in the Salmonella assay.

In the course of an ongoing screening of larger mushrooms for the occurrence of chemical mutagens, 33 out of 48 species tested exhibited a significant direct mutagenic activity in the Salmonella/microsome assay (Sterner et al., 1982). (No mutagens requiring metabolic activation were indicated.) These findings are of some concern, since mushrooms are used extensively as food in many areas, and there are strong indications that carcinogens in food are of considerable importance in cancer aetiology (Sugimura, 1979). A recent communication by Knuutinen and von Wright (1982) on the mutagenicity of 4 Lactarius species collected in Finland prompts us to report our own results from mutagenicity tests with commercially preserved (pickled) Lactarius necator.

Basidiomycota↗
PubMed1983

Preliminary characterization of the mutagenic properties of 'necatorin', a strongly mutagenic compound of the mushroom Lactarius necator.

The mutagenic activity of 'necatorin', a strongly mutagenic compound isolated from the wild edible mushroom Lactarius necator, was studied with the Ames test, the bacterial intraperitoneal host-mediated assay and the micronucleus test. Whereas the results of the Ames tests were clearly positive, no evidence of mutagenicity was detectable in host-mediated assays or micronucleus tests.

Agaricales↗
PubMed1984

Stability of necatorin, a highly mutagenic compound from Lactarius necator mushroom.

The mutagenic compound necatorin [7-hydroxycoumaro(5,6-c)cinnoline] was present in fresh Lactarius necator mushrooms at concentrations ranging from 3 to 20 mg/kg. Blanching decreased the concentration of necatorin in the mushrooms to about 25% of the original value. Pure necatorin was shown to be susceptible to decomposition by light, especially at high pH. The destruction of pure necatorin by boiling was most effective at pH 5.0, whereas at the other pH values studied (0.5 and 13.5) necatorin was relatively stable during boiling.

Agaricales↗
PubMed2002

Impact odorants contributing to the fungus type aroma from grape berries contaminated by powdery mildew (Uncinula necator); incidence of enzymatic activities of the yeast Saccharomyces cerevisiae.

Powdery mildew due to the fungus Uncinula necator is an important disease for the vineyard. The development of the fungus at the surface of the berries leads to the occurrence of a very characteristic and sometimes intense mushroom-type odor cited as an important default for grapes quality. Gas chromatography/olfactometry, gas chromatography, and multidimensional gas chromatogaphy/mass spectrometry techniques were used to investigate the most important odorants of grapes diseased by powdery mildew. Among 22 odorants detected, strongly odorant compounds were identified or tentatively identified in purified extracts obtained from grapes diseased by powdery mildew. Aroma extraction dilution analysis (AEDA) analysis revealed that 1-octen-3-one (mushroom odor), (Z)-1,5-octadien-3-one (geranium-leaf odor), and an unidentified odorous zone (fishy-mushroom like odor) were the most potent volatiles of the diseased grapes. In the presence of nonproliferating Saccharomyces cerevisiae yeast cells, and consequently during alcoholic fermentation, the enzymatic reduction of 1-octen-3-one and (Z)-1,5-octadien-3-one to much less odorant compounds, namely 3-octanone and (Z)-5-octen-3-one, was shown. Those results explain to some extent the disappearance of the fungal aroma specific to powdery mildew grapes during alcoholic fermentation.

Ascomycota↗
PubMed2005

Genetic relationships among members of the Ichthyobodo necator complex: implications for the management of aquaculture stocks.

Abstract Ichthyobodo necator (costia) is a common and important flagellate parasite that infests the skin and gills of many freshwater and marine fish. Costia infestations are often fatal and cause significant aquaculture losses worldwide. Recently it has been demonstrated that Ichthyobodo is a multispecies complex with differing host preferences. Knowing if those species have broad or narrow host specificity has important implications for the management of costia. To address the question of host specificity, genomic DNA was isolated from Ichthyobodo trophonts collected from rainbow trout, Oncorhynchus mykiss, koi, Cyprinus carpio, mirror carp, C. carpio, goldfish, Carassius auratus, channel catfish, Ictalurus punctatus, swordtail, Xiphophorus helleri, and Japanese flounder, Paralichthys olivaceus. The small subunit ribosomal RNA (SSU rRNA) gene from each isolate was analysed with previously published Ichthyobodo sequences using Bayesian phylogenetic methods. The internal transcribed spacers (ITS) from six isolates were also PCR-amplified, cloned and sequenced. Both the SSU rRNA phylogenetic analysis and the ITS rRNA sequence data support grouping the 22 Ichthyobodo isolates examined into a complex of nine different species. Many of these species were frequently isolated from multiple hosts, indicating that exchange of infested fish from one region to another has a high potential for spreading the disease. In one instance, the same species was obtained from marine and freshwater fish, further suggesting that certain Ichthyobodo species may not be limited by salinity.

Animals↗
PubMed1998

Oral pharmacological treatments for parasitic diseases of rainbow trout oncorhynchus mykiss. III. Ichthyobodo necator.

A total of 32 drugs were evaluated as regards their efficacy for oral treatment of Ichthyobodo necator infestation of rainbow trout. In preliminary trials, all drugs were supplied to infected fish at 40 g per kg of feed for 10 d. The majority of the drugs tested (1,3-di-6-quinolylurea, aminosidine, amprolium, benznidazole, bithionol, chloroquine, diethylcarbamazine, dimetridazole, diminazene aceturate, febantel, flubendazole, ketoconazole, levamisole, mebendazole, netobimin, niclosamide, niridazole, nitroscanate, nitroxynil, oxibendazole, parbendazole, piperazine, praziquantel, ronidazole, sulphaquinoxaline, tetramisole, thiophanate, toltrazuril and trichlorfon) were ineffectdive. Metronidazole and secnidazole were 100% effective (unlike the other nitroimidazoles tested, namely dimetridazole, benznidazole and ronidazole). The non-carbamate benzimidazole triclabendazole was likewise 100% effective.

Administration, Oral↗
PubMed1976

Antigen-induced lymphocyte blastogenesis in a hookworm (Necator americanus) infection in man.

A lymphocyte blastogenic technique was employed to examine cell-mediated immunity in a Necator americanus infection. Infective third-stage larvae of N. americanus were jsed for antigen preparation, and lymphocyte cultures were prepared from peripheral blood taken on days 3, 17, and 51 after infection with 250 third-stage larvae of N. americanus. At 3 days post-infection lymphocyte transformation was not induced; at 17 and 51 days after infection significant transformation was obtained.

Hookworm Infections↗
PubMed1984

[Geographic distribution of Ancylostoma duodenale and Necator americanus in Taiwan].

In order to determine the geographical distribution of Ancylostoma duodenale and Necator americanus in Taiwan, 2,759 fresh stool samples were collected from 5th-grade school children of both sexes among 43 preliminary schools in 16 counties, and then examined by means of the modified test-tube filter-paper cultivation method for identification of the filariform larvae of hookworm. Both species of A. duodenale and N. americanus are widespread in Taiwan. The overall infection rate was 20.00%. The rate of A. duodenale, N. americanaus and mixed infection of both species was 9.85%, and 7.75% and 2.39% respectively. Geographically, N. americanus (12.64%) predominated over A. duodenale (5.43%) in the north (Ilan, Taipei, Taoyuan, Hsinchu and Miaoli) and the east (Taitung) areas. On the contrary, A. duodenale (13.40%) predominated over N. americanus (5.63%) in the central (Nantou, Taichung, Changhua and Yunlin), the south (Chiayi, Tainan, Kaohsiung and Pingtung) and the east (Hualien) areas. On the other hand, the rate of infection on the offshore island (Penghu) was much lower (1.19%) than the others (21.10-21.29%).

Ancylostomiasis↗