Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Maxillofacial Abnormalities”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources

[A new device for reproducible computerized tomography in improved diagnosis of surgical maxillofacial conditions].

The aim of this study was the evaluation of a newly developed radiotranslucent headholder (craniostat) in order to improve diagnosis of maxillofacial pathology. In this prospective study, 103 patients with maxillofacial pathology were examined preoperatively with a Philips SR 7000 computed tomograph using this craniostat. The apparatus was applied fixing the patient's head at three points (meatus acusticus externus on both sides and the glabella). The control group consisted of 106 patients with similar pathology who were examined by computed tomography without a headholder. The application of the craniostat resulted in the following advantageous findings: (1) reproducible CT scans, therefore very precise assessment of the course of a disease; (2) fewer motion artifacts; and (3) symmetrical posture of the patient's head. This headholder is helpful in improving maxillofacial diagnosis by computed tomography if a symmetrical, reproducible posture of the patient's head is to be achieved and motion artifacts could otherwise make the interpretation of the resulting images much more difficult.

Adolescent↗

[Orthognathic surgery: corrective bone operations].

The article reviews the history of orthognathic surgery from the middle of the last century up to the present. Initially, mandibular osteotomies were only performed in cases of severe malformations. But during the last century a precise and standardized procedure for correction of the mandible was established. Multiple modifications allowed control of small fragments, functionally stable osteosynthesis, and finally a precise positioning of the condyle. In 1955 Obwegeser and Trauner introduced the sagittal split osteotomy by an intraoral approach. It was the final breakthrough for orthognathic surgery as a standard treatment for corrections of the mandible. Surgery of the maxilla dates back to the nineteenth century. B. von Langenbeck from Berlin is said to have performed the first Le Fort I osteotomy in 1859. After minor changes, Wassmund corrected a posttraumatic malocclusion by a Le Fort I osteotomy in 1927. But it was Axhausen who risked the total mobilization of the maxilla in 1934. By additional modifications and further refinements, Obwegeser paved the way for this approach to become a standard procedure in maxillofacial surgery. Tessier mobilized the whole midface by a Le Fort III osteotomy and showed new perspectives in the correction of severe malformations of the facial bones, creating the basis of modern craniofacial surgery. While the last 150 years were distinguished by the creation and standardization of surgical methods, the present focus lies on precise treatment planning and the consideration of functional aspects of the whole stomatognathic system. To date, 3D visualization by CT scans, stereolithographic models, and computer-aided treatment planning and simulation allow surgery of complex cases and accurate predictions of soft tissue changes.

Europe↗

[Callus distraction of the mid-face in severe mid-face hypoplasia].

Callus distraction in the treatment of severe midfacial hypoplasia/atrophy may offer new therapeutical possibilities. Between May 1998 and March 1999, six patients underwent a subtotal Le Fort I-II osteotomy with subsequent distraction via a haloborne distractor (RED). Five patients suffered from CLP, four patients were totally or almost edentulous in the upper jaw. Corrections of sagittal discrepancies were possible in all cases (distraction 16-31 mm). No case of increased velopharyngeal insufficiency was seen. In one patient the halo had to be refixed. Three patients suffered from tension-like pain in the soft palate during distraction. Follow-up studies suggest the necessity for overcorrection of 20% in edentulous senior patients. Callus midfacial distraction is a promising new alternative to conventional orthognathic surgery in severe cases.

Adolescent↗

Esthetic aspects of orthodontic-surgical treatment of sagittal-vertical anomalies: the example of the short face syndrome.

BACKGROUND: Psycho-esthetic aspects play an important role in motivating patients to undergo combined orthodontic-surgical treatment as well as in the subjective appraisal of treatment outcome. The facial soft tissues are the crucial interlink between the underlying skeletal and dental structures and their perception by the patient and his social environment. TREATMENT OF SHORT FACE SYNDROME: In the therapy of Class II malocclusions with skeletal deep bite and short lower face (short face syndrome), the soft tissues and the psycho-esthetic treatment expectations of the patient are taken systematically and appropriately into account during treatment planning and evaluation. PATIENTS AND METHOD: The respective elements of the treatment concept are outlined and explained in this article. Based on the empirical evaluation of 15 patients treated according to this concept, the soft tissue changes in patients with short face syndrome and the changes in esthetic and psychosocial self-perception are reported. RESULTS: The results demonstrate the efficiency of the treatment concept in improving facial soft tissues, especially in the vertical dimension, and the resulting psycho-esthetic benefit to the patient.

Adult↗

[Trans-facial distraction of the facial skull at the LeFort III level].

BACKGROUND: Several craniofacial deformities and syndromes feature hypoplasia of the midface skeleton. Until now different treatment options were based primarily on a modified LeFort III osteotomy: (1) the conventional LeFort III osteotomy with bone transplantation and intraoperative osteosynthesis, (2) distraction using subcutaneous distraction devices fixed on both sides at the os zygomaticum, and (3) bone distraction using a rigid external distraction device (RED distractor), which is fixed to the skull and pulling at the maxilla or the upper teeth. METHODS AND RESULTS: A modification of the distraction technique using the RED distraction device is presented. The tensile forces are applied to the ramus infraorbitalis or the apertura piriformis, and the tensile wires penetrate through the skin laterally to the nose. By using this new approach near the center of rotation or the center of resistance, optimal control of the vector of distraction is guaranteed. With sufficient distraction of the midface, overcorrection of the os zygomaticum can be avoided. Clinical data of seven patients are presented. DISCUSSION: Due to the good clinical results, external transfacial distraction with tensile forces pulling at the apertura piriformis seems to improve the treatment of these complex facial deformities.

Acrocephalosyndactylia↗

[Surgical lengthening of the lower face in patients with class II deformities and skeletal deep bite--"short face syndrome" controlled clinical study on the "Würzburger Konzept"].

Among Angle Class II patients scheduled for orthognathic surgery, those with short face syndrome with skeletal deep bite only make up a small portion. Nevertheless, it represents a complex challenge for the orthodontist as well as for the surgeon with respect to the individual treatment goals. The harmony of facial relations is impaired in these patients: The skeletal lower face and consequently the soft tissue profile show a deficit in height compared to the midface. Lengthening of the lower face with its respective effect on facial aesthetics can only be corrected by causal therapy, i.e., a combined approach with surgical enlargement of the gonion angle. In this study, a therapy concept specifically suited for the correction of Class II deformities with short face syndrome is presented. Consequences for the skeletal and dental situation with their benefit for extraoral appearance were tested in a clinical trial ( n=15, patients with class II deformities and short face syndrome). To evaluate skeletal and dental changes, cephalograms were taken prior to initiation of orthodontic treatment, 3 days after surgery but before initiation of postsurgery orthodontics, and 1 year after the end of treatment.

Adult↗

[Analysis of quality of life in patients with a facial prosthesis].

OBJECTIVE: This clinical study examined the quality of life of face-disabled patients who had received a facial prosthesis. PATIENTS AND METHODS: The examination of the 58 patients was performed using different questionnaires. For the evaluation of the subjective health-related quality of life an instrument constructed by the WHO was used (WHOQOQL-Bref). The Frankfurter Scales of Body Concepts (FKKS) was chosen to measure the self-assessment of the patient's own body perception. For the assessment of the present general quality of life a visual analogue scale was used (Anamnestic Comparative Self-Assessment, ACSA). Additionally an ad hoc questionnaire was used, which registers the post-therapeutic epithetic rehabilitation. The health-related quality of life of this sample was compared to a healthy one of the normal population. RESULTS: The examinations showed that the quality of life of the patients is reduced in contrast to the healthy group when the acquired defects were located in the region of the eye and the nose. The evaluation of the scales of body concepts showed that the patient's own body image was significantly altered. Body contact with other persons and their own sexual attraction was perceived as remarkably diminished. The patients believed that they spread an unpleasant odor. It is surprising that the wearers of a facial prosthesis indicated that they did not notice a restriction in the acceptance of their body by others. The influence of the application of camouflage did not have an impact on the quality of life. CONCLUSION: To improve the restricted quality of life, to the raise the reduced well-being and to strengthen the altered body experience, psychological care should be provided besides further optimization of the surgical-epithetic therapy and the camouflage technique.

Adaptation, Psychological↗

[Perioperative antibiotic prophylaxis in orthodontic bone operations of the facial skull].

Intraoral orthognathic surgical procedures are clean-contaminated operations because of the facultative pathogenic flora of the oral cavity. Without antibiotic prophylaxis in this kind of operation a postoperative wound infection can be expected in 20-31% of cases. Therefore, a retrospective analysis of the clinical course of 545 patients with various dentofacial deformities was performed to evaluate the importance of perioperative antibiotic prophylaxis. The total rate of wound infections was 2.8% and lower than rates published in other comparable studies without antibiotic prophylaxis. The rate of wound infection after single mandibular osteotomy (4.1%) was significantly higher than the analogous amount after single maxillary osteotomy (0.8%) because of the mechanical strain of the surgical wound in the region of the mandibular angle and because of the high retention of food particles and other decay products in this area. The recognized rise in the wound infection rate by increasing the length of operation demonstrates that the extent of bacterial contamination of the surgical wound depends on the dimension and duration of surgery. Bacterial flora caused the noticed wound infections in 61.5% of cases aerobic-anaerobic mixed infections, which is in accordance with the results of similar publications. With increasing length of antibiotic prophylaxis, an increase in the incidence of antibiotic-associated side effects and in the wound infection rate could be observed. Therefore, an antibiotic prophylaxis which exceeds 3 days does not seem to be useful. In this study, in which cephalosporins were mostly used, the total rate of antibiotic-associated side effects (4.6%) was lower than analogous amounts of other groups of antibiotics. The analysis demonstrates that a short-term prophylaxis with broad-spectrum cephalosporins such as cefatoxime of 48 h is very effective and useful.

Adolescent↗

The enigma of facial beauty: esthetics, proportions, deformity, and controversy.

The study of the face and the ability to alter its form have fascinated mankind for thousands of years. The clinical ability to alter dentofacial form, whether through orthodontics, facial growth modification, or surgery, requires an understanding of facial beauty, including the evaluation of facial esthetics, proportions, and symmetry. The purposes of this article were to give a brief contemporary overview of our concepts of facial beauty and esthetics and to consider a long-standing and controversial debate on the treatment of patients with dentofacial deformities.

Beauty↗

Autosomal dominant osteopetrosis and maxillomandibular osteomyelitis.

Osteopetroses represent a heterogeneous group of rare, hereditary bony dysplasias. They range from a devastating neurometabolic disease (including severe malignant infantile osteopetrosis) to 2 more benign conditions principally affecting adults: autosomal dominant osteopetrosis (ADO) type I and type II. The present study describes the maxillofacial manifestations associated with the 2 subgroups of ADO. In this paper, we present the oldest patient described in the literature with ADO type I (76 years old). We also document the first ADO type II patient described in the literature with synchronic osteomyelitis of the mandible and the maxilla.

Aged↗

[Digital volume tomography using the NewTom system: advantages of this new technique in children].

In some cases, after preliminary clinical examination, medical imaging can provide indispensable complementary information for the care of young patients. Volume imaging using two- and three-dimensional reconstructions provides the most complete information possible. Problems involving the superposition of anatomical structures, which can occur with conventional X-rays, are a thing of the past, and this technique represents the future in this field. In high-density tissue such as bone or teeth, tomodensitometry is the preferred examination as it can give a three-dimensional approach to the study. However, because of the high radiation dose required, scanner is still a second intention examination. Development of digital volume tomography using NewTom system, designed for maxillofacial exploration, produces the same type of image for a very much reduced X-ray dose, and at low cost. Although the use of this new examining technique is developing rapidly in Europe and throughout the world since its recent introduction, France is lagging behind as to date there are only seven machines in the entire country. The main uses in children, illustrated by original clinical cases, relate to preoperative surgery planning, post-trauma diagnostic workups, orthodontic checkups, postoperative follow-up and TMJ examinations. The purpose of this article is to inform dental surgeons, paediatricians and doctors about this new medical imaging examination, which will most definitely have a place in the battery of diagnostic tools available to us. After weighing the advantages/risks involved, it should be possible to reduce the number of tomodensitometry exams in favour of this new examination technique in children according to the clinical examination data and diagnostic information required.

Child↗

Thelarche variant in a girl with Angelman syndrome.

A case of Angelman syndrome (AS) with thelarche variant in a 4.5-year-old girl is presented. Clinical suspicion of AS was raised at the age of 15 months when she presented with mental retardation and epilepsy, absence of speech, ataxic gait with jerky movements, hyperactivity and paroxysmal episodes of laughter. Moreover, she had facial dysmorphic features such as microbrachycephaly, mid-facial hypoplasia, macrostomia and prominent mandible. Dinucleotide repeat polymorphism (DNRP) analysis, identified absence of maternal alleles at D15S543, D15S113 and GABRB3 loci, findings consistent with AS. Studies on CYP19 locus (outside the 15q11-13 region) revealed the presence of two different alleles, thus excluding the possibility of paternal isodisomy of chromosome 15 in this patient. Breast development at the age of 4.5 years, accompanied by accelerated growth velocity and bone age suggested the diagnosis of variant thelarche. This is the second case of AS with sexual precocity reported and whether this combination is a coincidence or not remains to be clarified.

Alleles↗

Combined push-pull distraction for correction of syndromic midfacial hypoplasia.

PURPOSE: Gradual midfacial advancement, applying the principle of distraction osteogenesis, reduces the restriction of the soft tissues and results in bony consolidation without need for grafting. The midface can be distracted by either pushing it forward, using semiburied devices, or pulling it forward by a rigid external device. For each method there are inherent technical problems, such as controlling the vector of movement, symmetry of advancement, and differential movement of the upper/lower face. We have used a combination of the 2 methods, called "push-pull," in an effort to control the distraction process. The purpose of this paper is to describe our push-pull distraction technique and summarize our early experience. MATERIALS AND METHODS: Ten patients (5 males and 5 females) with a mean age of 11 years 2 months underwent midfacial advancement using push-pull distraction. Two orthodontists, blinded for landmark identification, traced preoperative and postoperative cephalograms and determined linear and angular measurements of midfacial position. A Student t test was used to assess differences between the cephalometric measures on the 2 radiographs. Interexaminer reliability was calculated by an intraclass correlation coefficient. RESULTS: Postdistraction cephalograms were taken a mean of 10 months (range, 3 to 20 months) after removal of the devices. Patients exhibited improvement at all levels of the midface after distraction. There was a statistically significant sagittal advancement from the infraorbital rim to dentoalveolus. The central midface was sufficiently advanced as shown by an improved convexity, nasolabial angle, and upper labial protrusion. There were no significant differences between examiners for any of the measurements in this study. CONCLUSIONS: Push-pull distraction permits 1) equal movement at both the upper and lower facial levels, 2) advancement of the central midface, and 3) symmetric movement of the zygomaticomaxillary complexes. This method also provides a backup, in case one device malfunctions. In combination, the advantages of each device are additive; whereas the weaknesses are not. The push-pull technique is a practical method for midfacial distraction until a better single device is fabricated.

Acrocephalosyndactylia↗

Postsurgical stability of oropharyngeal airway changes following counter-clockwise maxillo-mandibular advancement surgery.

PURPOSE: This study evaluated oropharyngeal airway changes and stability following surgical counter-clockwise rotation and advancement of the maxillo-mandibular complex. METHODS AND PATIENTS: Fifty-six adults (48 females, 8 males), between 15 and 51 years of age, were treated with Le Fort I osteotomies and bilateral mandibular ramus sagittal split osteotomies to advance the maxillo-mandibular complex with a counter-clockwise rotation. The average postsurgical follow-up was 34 months. Each patient's lateral cephalograms were traced, digitized twice, and averaged to estimate surgical changes (T2-T1) and postsurgical changes (T3-T2). RESULTS: During surgery, the occlusal plane angle decreased significantly (8.6 +/- 5.8 degrees ) and the maxillo-mandibular complex advanced and rotated counter-clockwise. The maxilla moved forward (2.4 +/- 2.7 mm) at ANS and the mandible was advanced 13.1 +/- 5.1 mm at menton, 10 +/- 4.4 mm at point B, and 6.9 +/- 3.7 mm at lower incisor edge. Postsurgical hard tissue changes were not statistically significant. While the upper oropharyngeal airway decreased significantly (4.2 +/- 3.4 mm) immediately after surgery, the narrowest retropalatal, lowest retropalatal airway, and the narrowest retroglossal airway measurements increased 2.9 +/- 2.7, 3.7 +/- 3.2, and 4.4 +/- 4.4 mm, respectively. Over the average 34 months postsurgical period, upper retropalatal airway increased 3.9 +/- 3.7 mm, while narrowest retropalatal, lowest retropalatal airway, and narrowest retroglossal airway remained stable. Head posture showed flexure immediately after surgery (4.8 +/- 5.9 degrees ) and extension postsurgically (1.6 +/- 5.6 degrees ). CONCLUSION: Maxillo-mandibular advancement with counter-clockwise rotation produces immediate increases in middle and lower oropharyngeal airway dimensions, which were constrained by changes in head posture but remain stable over the postsurgical period. The upper oropharyngeal airway space increased only on the longest follow-up.

Adolescent↗

3D-CT evaluation of facial asymmetry in patients with maxillofacial deformities.

OBJECTIVE: The aims of this study were to characterize the symmetrical features of patients with facial deformities and to suggest a classification system for facial asymmetry based on 3-dimensional-computed tomography (3D-CT) evaluation. STUDY DESIGN: Preoperative CT images were investigated for 49 patients with maxillofacial deformities. Asymmetry indices were calculated for some landmarks in the maxilla, mandibular body and the mandibular ramus regions. RESULTS: Asymmetry was observed most frequently in the mandibular body region. The subjects were divided into 3 groups. Subjects without any asymmetry in the 3 regions were classified as Group I (44.9%). Groups II or III were defined for subjects without or with maxillary region asymmetry, respectively, and they were subcategorized. In Group IIA (8.2%), asymmetry was shown solely in the mandibular body region, and in Group IIB (18.4%), additional asymmetry was shown in the mandibular ramus region. Group IIIA (6.1%) showed asymmetry only in the maxillary region, and Group IIIB (22.4%) showed asymmetry in all 3 regions. CONCLUSION: The 3D-CT classification for facial asymmetry has the potential to replace the conventional cephalometric classification.

Case-Control Studies↗

Maxillofacial pathology and management of Pierre Robin sequence.

Pierre Robin sequence affects 1:8500 newborns and is characterized by cleft palate, micrognathia, and airway obstruction. Evolution in the understanding of the causes and pathogenesis of this condition is reviewed. Clinical findings and treatment options are also addressed. An overview of syndromes commonly associated with Pierre Robin sequence is provided.

Airway Obstruction↗