[Treatment of maxillary cancer with special reference to the surgical method].
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Early diagnosis of the maxillary antrum carcinoma is of considerable difficulty. There are, however, signs and a refined symptomatology that the stomatologist can recognize when the tumour is still in its intrinsic form. Although the maxillary antrum tumors are rare, they present an extremely difficult diagnosis. The patient comes to us when the tumor has already invaded all the contiguous structures pertaining to the oral cavity. For early diagnosis we can avail ourselves, besides a conventional radiographic test, also of more specific analysis, as the computed tomography and radio therapy. These last image methodologies are also employed to establish a radiation treatment plan. Actually the best therapeutic treatment seems to be the multidisciplinary one, combining therapy with surgery.
OBJECTIVE: To highlight the presentation of antral cancers in Nigerians. PATIENTS AND METHODS: Hospital records of all patients with a histologically diagnosed antral cancer who presented at the Lagos University Teaching Hospital (a tertiary referral centre) over a 16 year period were analysed. RESULTS: 28.7% of orofacial cancers and 12.6% of head and neck cancers were located in the antrum. 54.1% were squamous cell carcinoma, 27.4% were minor mucus gland carcinoma and 14.8% were mesenchymal cancers. Males were more frequently affected (ratio 1.7 to 1) and were relatively younger (peak age = 4th decade) than females (peak age = 6th decade). Males who had squamous cell carcinoma (x = 47.5 +/- 18.8 years) were relatively younger than their female counterparts (x = 57.2 +/- 13.8 years). But females with minor mucus gland carcinoma were relatively younger (x = 34.2 +/- 19.5 years) than males (x = 49.1 +/- 17.9 years). All patients had facial swelling at presentation and the most frequent initial symptom was toothache (36.2%). Fifty-two percent had prior treatment and the most common was an extraction of a molar tooth (50%). Two-thirds of the patients were of low socio-economic status. CONCLUSION: Antral cancer constituted sizeable proportion of orofacial and head and neck cancers in Nigerians. Clinicians need to maintain a high index of suspicion in cases of maxillary molar toothache or mobility of obscure aetiology. Predisposing aetiologic factors of this disease peculiar to our environment need to be further investigated.
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The osteocutaneous fibula free transfer with three segments of bone and the peroneal flap was used to reconstruct a total unilateral maxillectomy defect. Satisfactory restoration of three-dimensional facial structure, orbital support, and prosthesis wearing was achieved. The fibula osteocutaneous free flap is a very useful alternative for reconstructing a maxillectomy defect.
Trotter's syndrome is a clinical triad of unilateral deafness, neuralgia affecting branches of the trigeminal nerve, and defective mobility of the soft palate, which is caused by malignant tumors involving the lateral pharyngeal recess (Rosenmüller's fossa). It is an ominous presentation, which can masquerade as dental or masticatory pain. Computerized tomography (CT) can be used not only to explain the anatomic basis of Trotter's syndrome but also to determine the extent and distribution of the malignant tumor involved. The advantages of CT over conventional radiography are illustrated by a case of adenoid cystic carcinoma that presented as Trotter's syndrome. Perineural invasion by tumor is shown on the gross level for the first time with CT, and important diagnostic considerations, which may aid in the early diagnosis of future cases, are discussed.
An unusual malignant odontogenic tumor containing large numbers of ghost cells is described. A 46-year-old white man had an aggressive lesion of the right maxilla, multiple pulmonary nodules developed, and he died 1 year after initial diagnosis. Histologic features included columnar odontogenic epithelium, malignant epithelium, microcysts, masses of ghost cells with focal calcification, and small areas of "dentinoid." The relationship is explored between this tumor and calcifying odontogenic cysts, particularly the "dentinogenic ghost cell tumor" variant.
Ameloblastoma of the maxilla is an unusual epithelial tumor of odontogenic origin. Although it is considered benign, it can behave in a slowly growing infiltrative fashion, with multiple recurrences and eventual intracranial, or even distant, spread. Information on this tumor consists, to a large extent, of case reports presented in the oral surgery literature. This study is a retrospective review of our combined institutional experience with nasomaxillary tumors from 1980 to 1988. Among these cases were four patients with maxillary ameloblastoma, two males and two females, ranging in age from 16 to 66 years at presentation. Disease extent varied from ameloblastoma localized to a cyst in the maxillary sinus to extensive maxillary and ethmoid involvement. Follow-up ranged from 2 to 13 years, and disease course varied from apparent disease control to persistent intracranial tumor, despite attempts at extirpation. An analysis of this experience and the related literature is presented, along with recommendations for radical therapy, when appropriate, to best ensure control.
A rare case of angiosarcoma of the maxilla is presented. It was treated with embolisation, radiotherapy, chemotherapy and surgery but resulted in death 14 months after initial presentation. Review of the literature shows three other cases of primary angiosarcoma of the maxilla and six of the maxillary sinus treated with poor results.
A chloroma is described in the left quadrant of the maxilla in a 4-year-old girl. This patient had previously completed a course of chemotherapy for acute myeloid leukaemia, but had been off all drug therapy and in remission for 1 year prior to presentation. Chloroma is a well recognised, if uncommon, mode of presentation of acute myeloblastic leukaemia and a previous case of chloroma occurring in the mandibular gingival tissues has been reported (Reichart et al., 1984). An unusual feature in the present case is the appearance of the chloroma as a form of leukaemic relapse and as a solitary deposit which is itself uncommon in acute myeloblastic leukaemia. It is suggested that this chloroma was a leukaemic deposit which had spread from within the maxillary antrum or the tissues adjacent to the meninges.