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Prevalence of antimicrobial resistance in Haemophilus influenzae in Greece, Israel, Lebanon and Morocco.

Between 40 and 43 Haemophilus influenzae isolates obtained from Greece, Lebanon, Israel and Morocco respectively (a total of 167 strains) were analysed for prevalence of resistance to six different drugs. Of these isolates 12.6% produced beta-lactamase and were resistant to ampicillin. All isolates, except a single strain from Greece, were susceptible to cefaclor. The frequency of resistance to chloramphenicol and tetracycline was below 2%. The frequency of isolates susceptible and resistant to erythromycin and cotrimoxazole varied from country to country.

Ampicillin Resistance↗

[Treatment of fractures by traditional healers in Morocco].

Traditional traumatologists, specialized in the treatment of fractures, practise throughout Morocco. Their original technique is described and its efficiency evaluated through twenty or so cases studied during three years of medical work in the Great South of the country. Theories are propounded to explain the population's preference for these treatments to the detriment of the medical methods, which have a bad reputation. In the present situation, the medical infrastructure is unable to replace the benefits of these bonesetters, neither in quality--with the exception of the main centres-nor, above all, in quantity. Their activities are decentralized, socially integrated and economical for both the population and the state. These considerations lead to the conclusion that their practice should be maintained, improving it if need be.

Adolescent↗

Epidemiology of Strongylus vulgaris infection of the horse in Morocco.

Between August 1978 and July 1979 the anterior mesenteric artery and its branches were collected regularly from adult horses and examined for Strongylus vulgaris larvae. The incidence of infection varied from 55 to 100% (annual mean 80%). The mean monthly number of larvae ranged form 3 to 22 with an annual overall mean of 13. The arterial infection was at its minimum in December to January, rose gradually to attain the peak in June and declined thereafter. These observations indicated that S. vulgaris is an annual species in Morocco, infection occurring during the rainy season (November-April), the heavy arterial population in spring and adult population during autumn and winter.

Animals↗

Prevalence of cattle ticks in Morocco.

During July 1980 the prevalence of cattle ticks was studied in 4 bioclimatic regions of Morocco. All the 24 farms examined were infested. The mean number of ticks per animal varied from 6.5 to 36.3 in different regions. Eight species of ticks were identified: Hyalomma marginatum, H. detritum, H. lusitanicum, H. anatolicum, Boophilus annulatus, Rhipicephalus sanguineus, R. turanicus, R. bursa. Numerically H. detritum (30.8%) H. marginatum (25.5%) and B. annulatus (29.2%) were most important. The 3 Rhipicephalus species together formed only 3.9% of the total tick population. H. marginatum and H. lusitanicum were present in all the 4 climatic zones studied.

Animals↗

Endemic goiter in Morocco (Skoura-Toundoute areas in the high atlas).

Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urinary iodine excretion, measured on untimed samples, was low both in goitrous patients, m = 18 micrograms/l (n = 109) and in non goitrous subjects, m = 24 micrograms/l (n = 47). The value found in a nonendemic region (Casablanca) was much higher m = 117 micrograms/l (n = 67). Another approach to evaluate iodine intake per day was the analysis of iodine content of some samples of cereals (barley, wheat and corn), drinking water, sea and rock salt, cow and breast milk. Iodine content is low, specially in the endemic area: barley = 90 micrograms/kg (n = 1); wheat = 227 micrograms/kg (n = 1); corn = 91 micrograms/kg (n = 1); water = 0.92 to 1.30 micrograms/l (n = 3); cow milk = 6 to 33 micrograms/l (n = 10) breast milk = 10 to 55 micrograms/l (n = 14); rock salt = 420 to 660 micrograms/kg (n = 8); sea salt = 90 to 160 micrograms/kg (n = 4). Sodium chloride intake per day, estimated by the measurement of sodium and chloride urinary excretion, is normal both in the Skoura-Toundoute areas (10.7 g and 9.8 g for goitrous and nongoitrous subjects, respectively) and in Casablanca (10.9 g for control persons). Altogether the results demonstrate the importance of introducing the practice of iodinated salt in the prophylaxis of endemic goiter in this area.

Adolescent↗

On the reintroduction of the Mhorr gazelle in Tunisia and Morocco.

The Mhorr gazelle (Gazella dama mhorr) became extinct in the wild in the 1960s. The current world zoo population amounts to some 240 animals, going back to only 12 founders. In a cooperate international operation Mhorr gazelles of European zoo populations were successfully reintroduced to national parks and nature reserves in Morocco and Tunisia in the years 1990/1992. The genetical and ecological prerequisites as well as the breeding aspects are discussed.

Animals↗

The epidemic threshold of vector-borne diseases with seasonality: the case of cutaneous leishmaniasis in Chichaoua, Morocco.

Cutaneous leishmaniasis is a vector-borne disease transmitted to humans by sandflies. In this paper, we develop a mathematical model which takes into account the seasonality of the vector population and the distribution of the latent period from infection to symptoms in humans. Parameters are fitted to real data from the province of Chichaoua, Morocco. We also introduce a generalization of the definition of the basic reproduction number R (0) which is adapted to periodic environments. This R (0) is estimated numerically for the epidemic in Chichaoua; approximately 1.94. The model suggests that the epidemic could be stopped if the vector population were reduced by a factor approximately 3.76.

Animals↗

Nocturnal activity of phlebotomine sandflies (Diptera: Psychodidae) in a cutaneous leishmaniasis focus in Chichaoua, Morocco.

The nocturnal activity of phlebotomine sandflies (Diptera: Psychodidae) was studied "at an epidemic focus" on human cutaneous leishmaniasis due to Leishmania tropica Wright in Chichaoua province, in Morocco. Sandflies were collected using light and sticky-paper traps changed at 2-h intervals, inside and around houses, in August and October 2004. Overall, 633 sandflies, belonging to six species of Phlebotomus and three of Sergentomyia, were collected. Sandfly activity was nocturnal and higher at twilight. Several activity patterns were observed according to the species. Phlebotomus (Paraphlebotomus) sergenti Parrot, 1917, the suspected vector of L. tropica in this focus, was caught during each collection performed from 1900 to 0500 hours, the numbers of species caught peaked at 1900-2100 hours. There were seasonal variations of the nocturnal activity, which could be related to the variations in temperature and relative humidity.

Animals↗

Distribution of gastrointestinal helminths in chicken farms in the Gharb region--Morocco.

Gastrointestinal tracts of 300 chickens from three villages of the Gharb region, Morocco, were examined for adult helminths during 2002-2005. Helminth species found were: Notocotylus gallinarum (prevalence 0.7%), Hymenolepis carioca (3.7%), Raillietina echinobothrida (5.7%), Hymenolepis contaniana (7%), Raillietina tretragona (9.3%), Raillietina cesticillus (12%), Capillaria obsignata (6%), Subulura brumpti (15.3%), Heterakis gallinarum (10%), Cheilospirura hamulosa (2.7%), Dispharynx nasuta (5.3%), Ascaridia galli (9%), and Tetrameres sp. (3.3%). The prevalence and mean intensity of helminth infections did not differ significantly between male and female chickens.

Animal Husbandry↗

Schistosoma haematobium: comparative studies on the characteristics of infection in three populations of Planorbarius metidjensis from the Agadir province in South Morocco.

Planorbarius metidjensis measuring 2 or 3 mm in diameter and originating from three populations in the Agadir province (Ida Ou Gnidif, Imouzzer, and Sidi Belkacem) were experimentally infected with Schistosoma haematobium to determine if the complete larval development of the parasite might be ensured by any snail population of the Agadir province and to compare the general characteristics of infection. No significant difference between the three populations was noted in the survival rates of snails when the first shedding occurred or in the prevalence of infection. The mean duration of the shedding period was significantly higher in the Imouzzer population (111 days versus 53-58 days). The total number of cercariae shed per mollusc was significantly lower in the Ida Ou Gnidif planorbids (1,398/snail versus 3,346 and 3,343/snail in the other 2 groups). The same rhythm in daily cercarial production was noted in the three snail groups, with the periodicity being 18-20 days. Despite some differences in parasite development between the three snail populations, the different populations of P. metidjensis can ensure the complete development of S. haematobium and maintain local transmission in the South of Morocco.

Animals↗

Serogroups, serotypes, serosubtypes and antimicrobial susceptibility of Neisseria meningitidis isolates in Casablanca, Morocco.

Since antigenic characterization and antibiotic susceptibility testing are useful for generating prophylactic recommendations and treatment guidelines, a total of 163 Neisseria meningitidis isolates obtained between January 1992 and September 2000 at the microbiology laboratory of the IbnRochd University Hospital of Casablanca, Morocco, were serogrouped, serotyped, serosubtyped and tested for their susceptibility to five antibiotics. Serogroup B was detected most frequently (75.5%), followed by serogroup A (13.5%). The phenotype B:4:P1.15 represented 74.8% of all serogroup B isolates. Seven (4.3%) isolates demonstrated decreased susceptibility to penicillin G. All isolates tested were susceptible to cefotaxime, chloramphenicol and rifampin. All isolates were inhibited by spiramycin at a concentration of 0.4 mg/l.

Anti-Bacterial Agents↗

Multivariate analysis of heavy metal contents in soils, sediments and water in the region of Meknes (central Morocco).

Concentrations of Al, Fe, Cr, Cu, Ni, Pb and Zn in soils, sediments and water samples collected along the Oued Boufekrane river (Meknes, central Morocco) were determined. In soils, a homogeneous distribution of metal concentrations was observed throughout the study area except for Pb, which presents high enrichment at sites located at the vicinity of a main highway. In sediments, high enrichment, with respect to upstream sites, were observed downstream of the city of Meknes for Al, Cr, Fe and Ni and inside the city for Cu, Zn and Pb. In water samples, the metal contents showed to correlate with their homologues in sediments suggesting that the metal contents in water and sediments have identical origins. Descriptive statistics and multivariate analysis (principal factor method, PFM) were used to assist the interpretation of elemental data. This allowed the determination of the correlations between the metals and the identification of three main factor loadings controlling the metal variability in soils and sediments.

Environmental Monitoring↗

Seasonal dynamics of Fasciola hepatica burdens in grazing Timahdit sheep in Morocco.

Seasonal transmission of Fasciola hepatica was observed in sentinel sheep and the dynamics of the snail intermediate host, Lymnaea truncatula, was followed over a 3-year study period in the Middle-Atlas mountains in Morocco. High fluke burdens were recorded in both lambs and ewes in the fall and winter, suggesting that transmission occurred in late spring. Fluke burdens ranged from one to 302 in ewes and from one to 345 in lambs. Infections with 200 or more flukes were always fatal. A unique feature of this study was the annual cyclical fluctuation of the fluke burdens. Burdens reached maximum levels during the winter and then declined to low numbers by late spring and summer. This suggested self-regulation which may be dependent on breed resistance or may be related to forage factors, including lack of forage (nutritional stress). Snail populations were cyclical and correlated with fluke transmission as observed in the sentinel sheep. The weather was observed to affect the snail populations which in turn limited fluke transmission.

Animals↗

Canine leishmaniasis in Morocco with special reference to infantile kala-azar.

Observations on canine leishmaniasis in Morocco (clinical symptoms, diagnosis, evolution, haematology, development of serum proteins, pathology and histopathology) are reported from dogs examined during 1979/80. Special reference is made to infantile kala-azar and its increasing incidence. The public health importance of dogs and wildlife as reservoir hosts is stressed, considering the close relationship of children with these animals and the possibility of contact transmission.

Animals↗

The epidemiology of tropical theileriosis (Theileria annulata infection in cattle) in an endemic area of Morocco.

A longitudinal study of tropical theileriosis was performed on 12 farms in the Doukkala region of Morocco during 1990. Adult Hyalomma detritum detritum were collected between March and early October and a peak in numbers was observed at the end of June. Nineteen percent (24/127) were infected with Theileria species and, amongst these, over 50% had five or more sporoblasts in their salivary glands (range 1-151). Hyalomma d detritum larvae and nymphs were found on cattle between September and early December with the highest numbers in late October. The prevalence of T. annulata piroplasm carriers at the beginning of the year was 48.5% (47 positive out of 97) and there were 14 new infections during the disease season (March to September) of which five developed into clinical cases. The incidence rates of new infection and clinical disease were 0.156 and 0.056 per animal-season, respectively. Differences were observed between age categories of cattle in both tick and parasite infections. A significantly lower number of adult H.d. detritum were collected from calves than from adult cattle. The prevalences of piroplasm carriers before the disease season were 0%, 36% and 76%, respectively, in (a) calves which had been born since the previous disease season, (b) calves born before then and (c) adults. However, the incidence rates of infection and disease for uninfected animals in the two categories of calves were approximately the same: 0.299 and 0.378 new infections, and 0.085 and 0.126 clinical cases per animal-season for (a) and (b), respectively. The date predicted for the appearance of adult H.d. detritum, based on published tick development times and local temperature records, was within 2 weeks of the study visit when the highest number of adults were collected from cattle. However, the date predicted for the appearance of larvae was 6 weeks earlier than the observed peak populations and may indicate that H.d. detritum delays either egg laying in the summer or larval host searching in the autumn.

Age Factors↗

Stomach parasites of donkeys in Morocco: habitat and interspecific interactions.

One hundred and four donkeys originating from several regions of Morocco were necropsied during 1 year. The parasites in their stomachs were counted and locations determined in the cardiac, fundic and pyloric portions. Synergistic or antagonistic interactions between parasites were assessed by a principal component analysis. Gasterophilus intestinalis was only found in the cardiac portion and G. nasalis was mostly found in the pyloric portion. Habronema were principally encountered in the pyloric portion, whereas Trichostrongylus axei was found in the fundic portion. The parasites were synergistically associated in their habitat interaction, except for T. axei on the fundic portion which was antagonistic to other parasites.

Animals↗

Factors influencing the transmission and incidence of tropical theileriosis (Theileria annulata infection of cattle) in Morocco.

A longitudinal epidemiological investigation of tropical theileriosis was carried out in an endemic region of Morocco during the 1991 disease season. This involved approximately 220 cross-bred cattle on 15 farms. Data were collected on the frequency of existing infections, the size of the vector tick population and the incidences of new infections and clinical disease, and these were then analysed using statistical models. The prevalence of subclinically infected carriers of Theileria annulata, the number of adult Hyalomma detritum, the vector, and the probability of becoming newly infected with T. annulata increased significantly with the age of cattle, although the age effect on new infections may be a result of increased tick numbers on older animals. The probability of clinical disease in newly infected cattle was not significantly influenced by age or by the number of adult ticks, but was significantly positively associated with the cattle population on the farm. The number of H. detritum nymphs counted on cattle in the autumn was related significantly to the previous adult tick count on the same animal.

Animals↗

Epidemiological aspects of lungworm infections of goats in Morocco.

The results of a survey of lungworm infections in goats in the Middle Atlas and Rabat areas in Morocco during 1990-1992 are reported. Five species were recorded: Dictyocaulus filaria, Protostrongylus rufescens, Cystocaulus ocreatus, Muellerius capillaris and Neostrongylus linearis. The parasitological profile of protostrongylid species was represented by Muellerius (69-78%), Protostrongylus (16-25%) and Cystocaulus (5-6%) in the Rabat and Middle Atlas areas. Neostrongylus was virtually non-existent (under 1%) in both regions. Multigeneric infection involving several species of lungworms reached 54% in Rabat and 88% in Middle Atlas. Dictyocaulus infection of goats does not appear to be a serious problem. Infection rates of 40% and 50%, and average worm burdens of three and five worms per kid and adult goat were recorded in autumn in the Rabat area. A similar pattern was noted in Middle Atlas. In contrast, the incidence of small lungworm infections in goats is widespread at levels likely to be of economic significance. The level of infection was considerably higher than the Dictyocaulus infection and the infection rate was virtually 100% in both age groups in the two areas. The overall worm burdens averaged 77.03 +/- 22.6 parasites per adult goat and 44.16 +/- 16.3 per kid in the Rabat area, whereas the corresponding figures in Middle Atlas were 51.48 +/- 16.65 and 34.06 +/- 2.69 worms. The periods of high risk of infection by small lungworms were autumn, early winter and late spring-early summer. However, the heaviest infection by adult worms and the highest larval excretion were observed in late autumn and winter when molluscs were heavily infected. The periparturient period seemed to exert a positive influence on protostrongylid larval production. The output of first stage larvae (L1) of lungworms was significantly higher in goats than in sheep. Thus, goats may play a greater role in pasture contamination. The epidemiological factors influencing the seasonal fluctuations of lungworms are discussed and a timetable of recommended treatments is suggested.

Animals↗