Fluoroacetate inhibition of fatty acid oxidation by liver preparations; a mechanism of action.
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Fatty Acids↗
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Treatment of fluoroacetate poisoning in mice and dogs.
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Animals↗
Factors influencing fluoroacetate poisoning; practical treatment with glycerol monoacetate.
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Fluoroacetates↗
Citrate formation in vivo induced by non-lethal doses of fluoroacetate.
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Citrates↗
Citric acid content of normal and tumor tissues in vivo following injection of fluoroacetate.
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Citric Acid↗
The action of sodium fluoroacetate on intestinal smooth muscle.
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Fluoroacetates↗
The effect of sodium fluoroacetate on the contractility and metabolism of intestinal smooth muscle.
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Fluoroacetates↗
The effect of fluoroacetate on the sartorius muscle of the frog.
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Fluoroacetates↗
Absorption, distribution, and excretion of sodium fluoroacetate (1080) in rats.
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Animals↗
Acute poisoning with sodium fluoroacetate (compound 1080).
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Fluoroacetates↗
Fatal poisoning with sodium fluoroacetate; report of a case.
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Fluoroacetates↗
Cell-free biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya.
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Biotransformation↗
Biochemical effects of fluoroacetate poisoning in rat liver.
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Aconitate Hydratase↗
Some metabolic aspects of fluoroacetate especially related to fluorocitrate.
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Aconitate Hydratase↗
The influence of some sulfhydryl inhibitors and of fluoroacetate on the oxygen consumption of some Trypanosomes.
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Acetates↗
The metabolic characteristics of yeast cells treated with fluoroacetic acid: evidence of the regulation of glucose oxidation by pH.
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Carbohydrate Metabolism↗
Influence of 2 deoxy-D-glucose and sodium fluoroacetate on respiratory metabolism of rat embryos during organogenesis.
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Abnormalities, Drug-Induced↗
Biochemical aspects of fluoroacetate poisoning in isolated rat kidney tubules: reversibility of inhibition of gluconeogenesis by alpha-ketoglutarate.
The effects of monofluoroacetate (FAC) on suspensions of isolated rat kidney tubules were investigated. FAC inhibited gluconeogenesis from lactate, pyruvate, fructose, dihydroxyacetone, alpha-ketoglutarate, and succinate. The gluconeogenesis from pyruvate, ketoglutarate, and lactate was less sensitive to FAC than that from other substrates. FAC also caused a decrease in oxygen consumption, hydroxybutyrate to acetoacetate ratio, alpha-ketoglutarate, ATP, and total adenine nucleotide content; the citrate content was increased. Addition of alpha-ketoglutarate, 5 mmol/l, caused a reversal of gluconeogenesis inhibition, an increase in ATP content, and a delay in citrate accumulation in isolated rat kidney tubules incubated with FAC.
Adenosine Triphosphate↗