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The flare-up phenomenon in endodontics: a clinical perspective and review.

The acute endodontic cellulitis exacerbation, which can be potentially fatal, is a definitive entity in endodontic flare-ups. Aerobic microbes, particularly streptococci, are the predominant causative microbes isolated. There was a noticeable absence of obligate anaerobes. This is significant for the selection of an antibiotic for therapy. Treatment parameters were presented. An endodontic cellulitis exacerbation is most unlikely with obligate anaerobes. An endodontic flare-up perspective was attempted with some clinical parameters. The proponents of routine one-visit endodontic treatment with prophylactic drugs to prevent cellulitis exacerbations do not appear to offer any advantage to the more traditional approaches to endodontic treatment of the patient, which may be more beneficial.

Cellulitis↗

Comparison of prophylactic and on-demand diflunisal for pain management of patients having one-visit endodontic therapy.

To determine whether the posttreatment prophylactic use of diflunisal (Dolobid 500) would be more effective than the on-demand use of diflunisal in reducing endodontic posttreatment pain, the current open-label, randomized study was undertaken. After one-visit nonsurgical endodontic therapy, 100 patients with asymptomatic teeth having either vital-inflamed pulp, pulpal necrosis, or pulpal necrosis with periapical radiolucent lesion were randomly given either prophylactic diflunisal (two tablets immediately at the conclusion of the visit, then four tablets to be taken in the schedule of one every 8 to 12 hours for pain if needed) or on-demand diflunisal (same dosage schedule; pills to be taken only if needed). The outcome showed that compared to the on-demand usage, the posttreatment prophylactic administration of diflunisal resulted in a statistically significant reduction in the number of episodes of endodontic posttreatment pain that required analgesic intervention. It appears from the results of this study that the posttreatment prophylactic use of diflunisal is significantly more effective than the on-demand usage of diflunisal in reducing endodontic posttreatment pain for one-visit endodontic therapy with all types of originally asymptomatic endodontic conditions. Further studies are necessary to determine whether pretreatment prophylactic deflunisal would be more effective, and also the effectiveness of prophylactic diflunisal in reducing posttreatment pain in presenting symptomatic cases and for cases treated in multiple visits.

Adolescent↗

Modern endodontic practice: instruments and techniques.

Like many other dental and medical specialties, endodontics has evolved and changed over the years. The changes that have occurred in the past 10 years, however, have been of great magnitude and profundity. The microscope, ultrasonic units with specially configured tips, superbly accurate microchip computerized apex locators, flexible nickel-titanium files in rotary engines, and greater emphasis on microscopic endodontic surgery have totally changed the way endodontics and endodontic surgery are practiced. Comparing these changes with formocreoszol medication, K-file and radiographic determination of working length are truly dramatic. These changes are bringing the specialty of endodontic practice into the twenty-first century with greater precision, fewer procedural errors, less discomfort to the patient, and faster case completions. Seven key advancements in endodontics were made in the last decade. This article discusses these advancements and their applicability to everyday practice.

Dental Pulp Cavity↗

Endodontics and implants, a catalog of therapeutic contrasts.

Dentists may be faced with the choice to retain a tooth by performing endodontic therapy and restoration or to extract the tooth and replace it with an implant and restoration. The purpose of this study was to catalog areas where implant and endodontic therapies differ so as to assist dentists in making treatment decisions and in identifying areas deserving of future research. Differences in diagnostic procedures and prognostic indicators were listed. With respect to treatment outcomes, study designs, success criteria, treatment results, systematic reviews, complications, clinician expertise, and the use of patient-based measures were discussed. The need for clinically applicable consensus statements and treatment protocols was noted. It was concluded that at this time, choices between implant and endodontic therapies cannot be solely based on outcomes measurement evidence; that different modes of outcome measure frustrate direct comparison; that endodontic and implant therapies profoundly differ in many ways; that although rigorous and clearly defined outcome measures have been proposed for use in endodontic and implant outcomes studies, they are very rarely used; that long-term, large, clearly defined studies, with simple and clear outcome measures, for example survival in combination with defined treatment protocols, are needed to measure the clinical performance of endodontic and implant therapies; and it was recognized that broad outcomes data may not be sufficiently specific to directly impact clinical decision making.

Consensus↗

Risk of maxillary fungus ball in patients with endodontic treatment on maxillary teeth: a case-control study.

BACKGROUND: Maxillary sinus fungus ball (FB) is a noninvasive fungal disease commonly associated with symptoms of recurrent maxillary rhinosinusitis and/or extrusion of root canal filling material into the sinus. Chronic periapical inflammatory processes of dental origin are believed to be the risk factors in the pathogenesis of FB. The aim of this study was to determine whether endodontic treatment performed on maxillary molar, premolar, and canine teeth was a risk factor in the development of FB. METHODS: We designed a case-control study in which the cases were patients with FB admitted to the Department of Otorhinolaryngology at the University of Brescia between January 1990 and April 2005. For each case, 3 age-matched controls were randomly selected from the admission registry of the University Dental Clinic. Orthopantomography was used to detect endodontically treated maxillary molar, premolar, and canine teeth in both patients and controls. RESULTS: Of 102 patients with FB who were admitted during the study period, 91 (89.2%) had had endodontic treatment compared with 113 (36.9%) of 306 controls (chi square = 83.6601, P = 0.000; OR 14.13; 95% CI 7.25-27.54). The mean number (standard deviation; interquartile range [IQR]) of endodontic procedures was 1.39 (0.86; 1-2) in patients and 0.53 (0.81; 0-1) in controls (Mann-Whitney U test = -9.138, P = 0.0000). The interval between the endodontic treatment and the diagnosis of FB was available for 37 (36.3%) patients, and the median was 4 years (IQR 2-10). INTERPRETATION: Endodontic treatment on maxillary teeth is a strong risk factor for FB of the maxillary sinus.

Adult↗

Are endodontically treated teeth more brittle?

This study compared biomechanical properties (punch shear strength, toughness, hardness, and load to fracture) of 23 endodontically treated teeth (mean time since endodontic treatment: 10.1 yr) and their contralateral vital pairs. Analyses using paired t tests revealed no significant differences in punch shear strength, toughness, and load to fracture between the two groups. Vital dentin was 3.5% harder than dentin from contralateral endodontically treated teeth (p = 0.002). The similarity between the biomechanical properties of endodontically treated teeth and their contralateral vital pairs indicates that teeth do not become more brittle following endodontic treatment. Other factors may be more critical to failure of endodontically treated teeth.

Adult↗

Fracture strength and survival rate of endodontically treated maxillary incisors with approximal cavities after restoration with different post and core systems: an in-vitro study.

OBJECTIVES: This study compared the fracture strength and survival rate of endodontically treated crowned maxillary incisors with approximal class III cavities and different core build-ups. METHODS: Sixty-four caries free human maxillary central incisors were selected for standardized size and quality, endodontically treated and prepared with approximal cavities 3mm in diameter. Group 1 was restored with titanium posts, group 2 received zirconia posts, in group 3 the root canal was partially filled with a hybrid composite. In the control group, only the access opening was restored. All teeth were prepared for and restored with full cast metal alloy crowns and subsequently exposed to 1.2 million cycles in a computer-controlled chewing simulator with simultaneous thermocycling. In addition, the samples were loaded until fracture in a static testing device. RESULTS: One specimen with composite reinforced root canal did not survive the dynamic load test. The following median fracture strengths in Newtons for the different groups were: titanium post 1038, zirconia 1057, composite resin 750, control (no post) 1171. The fracture load in group 3 (composite resin) was significantly lower (P<0.05) than in the other groups. CONCLUSIONS: The reconstruction of endodontically treated single rooted teeth with approximal cavities can be successfully performed by closure of the endodontic and additional cavities with composite. Cementation of endodontic posts offers comparable but no advantageous fracture resistance. Enlargement of the root canal space after completion of endodontic treatment should be avoided and cannot be compensated for by injection of composite resin. Less catastrophic failures were observed without post reconstruction.

Chi-Square Distribution↗

Three-year clinical comparison of survival of endodontically treated teeth restored with either full cast coverage or with direct composite restoration.

STATEMENT OF PROBLEM: Little information exists regarding the outcome of crown build-ups on endodontically treated teeth restored with metal-ceramic crowns or with only a direct-placed composite. PURPOSE: The aim of this study was to evaluate the clinical success rate of endodontically treated premolars restored with fiber posts and direct composite restorations and compare that treatment with a similar treatment of full-coverage with metal-ceramic crowns. MATERIAL AND METHODS: Subjects included in this study had one maxillary or mandibular premolar for which endodontic treatment and crown build up was indicated and met specific inclusion/exclusion criteria. Only premolars with Class II carious lesions and preserved cusp structure were included. Subjects were randomly assigned to 1 of the following 2 experimental groups: (1) teeth endodontically treated and restored with adhesive techniques and composite or (2) teeth endodontically treated, restored with adhesive techniques and composite, and then restored with full-coverage metal-ceramic crowns. Sixty teeth were included in the first group and 57 in the second. All restorations were performed by one operator. Causes of failure were categorized as root fracture, post fracture, post decementation, clinical and/or radiographic evidence of marginal gap between tooth and restoration, and clinical and/or radiographic evidence of secondary caries contiguous with restoration margins. Subjects were examined for the listed clinical and radiographic causes of failure by 2 calibrated examiners at intervals of 1, 2, and 3 years. Exact 95% confidence intervals for the difference between the 2 experimental groups were calculated. RESULTS: At the 1-year recall, no failures were reported. The only failure modes observed at 2 and 3 years were decementations of posts and clinical and/or radiographic evidence of marginal gap between tooth and restoration. There was no difference in the failure frequencies of the 2 groups (95% confidence interval, -17.5 to 12.6). There was no difference between the number of failures caused by post decementations and the presence of marginal gaps observed in the 2 groups (95% confidence intervals, -9.7 to 16.2 and -17.8 to 9.27). CONCLUSION: Within the limitations of this study, the results upheld the research hypothesis that the clinical success rates of endodontically treated premolars restored with fiber posts and direct composite restorations after 3 years of service were equivalent to a similar treatment of full coverage with metal-ceramic crowns.

Adult↗

Molecular analysis of bacteria in asymptomatic and symptomatic endodontic infections.

The purpose of the present study was to use terminal restriction fragment length polymorphism analysis and the 16S rRNA gene clone library to investigate the diversity of the microbiota associated with asymptomatic and symptomatic endodontic infections and to compare the bacterial community structure in these two clinical conditions. Samples were taken from asymptomatic endodontic infections associated with chronic periradicular lesions and from symptomatic infections clinically diagnosed as acute abscesses. 16S rRNA genes from DNA isolated from clinical samples were used to construct clone libraries or were subjected to terminal restriction fragment length polymorphism analysis. Sequence analysis of 186 clones revealed 42 taxa; 23 (55%) were uncultivated phylotypes, of which seven were unique to endodontic infections. Clone sequencing and terminal restriction fragment length polymorphism analysis revealed that the most commonly detected taxa were Fusobacterium nucleatum (including terminal restriction fragment types 1 and 2), Peptostreptococcus micros/Peptostreptococcus sp. oral clone AJ062/BS044/FG014, Prevotella species, Dialister species, Mogibacterium species, Lachnospiraceae oral clone 55A-34, Filifactor alocis, Megasphaera sp. oral clone CS025/BS073, and Veillonella sp. oral clone BP1-85/Veillonella dispar/V. parvula. Bacteroides-like sp. oral clone X083/Bacteroidales oral clone MCE7_20 and Dialister sp. oral clone BS016/MCE7_134 were detected only in asymptomatic teeth. On the other hand, F. nucleatum terminal restriction fragment type 2, Prevotella intermedia, Dialister pneumosintes, and some phylotypes were exclusively detected in symptomatic samples. Bacterial profiles of symptomatic endodontic infections generated by terminal restriction fragment length polymorphism analysis were clearly different from those of asymptomatic infections. Overall, the average number of terminal restriction fragments in symptomatic samples was significantly larger than in asymptomatic samples. Molecular analysis of the microbiota associated with symptomatic or asymptomatic endodontic infections indicates that the endodontic bacterial diversity is greater than previously described by culture methods and that the structure of the microbiota differ significantly between asymptomatic and symptomatic infections.

Adolescent↗

A longitudinal study of changes in frequency and technical standard of endodontic treatment in a Swedish population.

Longitudinal studies of endodontic treatment are rare. The purpose of this investigation was to study changes in frequency, technical standard and treatment need in a Swedish population with an interval of 5-7 years. The number of endodontically treated teeth in the population increased while the number of periradicular radiolucencies was at about the same level at the second examination. The number of radiolucencies found in endodontically treated teeth was reduced while it was increased in untreated teeth. The number of root fillings ending less than or equal to 2 mm from the apex of the tooth as well as fillings with a proper seal had increased at the second examination, but still only 40.2% ended less than or equal to 2 mm from the apex of the tooth and 59.1% of the root fillings were judged to have a proper seal. It was concluded that a great need for endodontic treatment existed in the population examined. A slight improvement in the quality of the treatment was evident at the second examination. However, the technical standard was still poor and obviously affected the outcome of the treatment. It is the opinion of the authors that endodontic treatment methods should be simplified as much as possible in an effort to improve the technical quality of the treatment. The prognosis of endodontic treatment would then improve as well.

Adult↗

Endodontic pathogens: propagation of infection through patent dentinal tubules in traumatized monkey teeth.

Periapical pathology indicating endodontic infection, when present in marginal periodontitis-affected teeth, has recently been shown to be an aggravating factor in progression of marginal destruction. This has been associated with patency of dentinal tubules in the tooth cervix, an area normally devoid of cementum following periodontal therapy. These studies are, however hampered by that only circumstantial evidence such as presence of periapical destruction have been applied as criteria of endodontic infection. The purpose of the present investigation was to study to what extent a predefined selection of endodontic pathogens inoculated in the root canal can influence periodontal pathology and healing in areas of the root covered by or devoid of cementum, using root resorption as a histomorphometric marker. Exposed dentine surfaces, in the present study showed significantly larger areas of resorption in infected roots compared to non-infected roots, while cementum surfaces showed an almost identical distribution of tissue reactions regardless of root canal infection or not. It was concluded that endodontic pathogens or their products were not able to penetrate the cementum barrier. The significantly larger areas of resorption on exposed dentine surfaces in infected roots compared to non-infected roots indicated that endodontic pathogens or their products could spread through dentinal tubules to a root surface void of cementum. Extrapolated to the marginal situation this indicated that endodontic pathogens in the root canal might be able to aggravate marginal infection in areas of root devoid of cementum.

Animals↗

CONTROVERSIES IN ENDODONTICS.

Diseases of the dental pulp often have an infectious origin, and treatments are aimed to control infections of the root canal system. Endodontic treatment principles originally evolved on the basis of trial and error, and only in recent decades have scientific methods been adopted to support clinical strategies. Yet, relevant research on the disease processes, their diagnoses, and efficient treatment are rare in the endodontic literature. Hence, the advancement of biologically based knowledge significant to clinical endodontics has been slow. Therefore, many differences of opinion still prevail in this field of dentistry. This review highlights and analyzes the background of some of the more heavily debated issues in recent years. Specifically, it deals with disagreements regarding the clinical management of pulpal exposures by caries in the adult dentition, definitions of success and failure of endodontic therapy, and causes of and measures to control infections of the root canal system. Clearly, a most apparent gap in the published endodontic literature is the lack of randomized clinical trials that address the more significant controversial matters relating to the management of pulpal wounds, medication, and the number of appointments required for the treatment of infected root canals. However, trials in endodontics require extremely long follow-up periods if valid conclusions are to be generated. Therefore, it is not to be expected that there will be rapid solutions to these issues in the foreseeable future.

Journal Article↗

[Resistance to fracture of direct restorations with cuspal coverage in endodontically treated upper bicuspids].

Endodontically treated teeth are considered more susceptible to fracture because of the loss of tooth structure. The aim of this study was to evaluate the increase of resistance to fracture of upper bicuspids that underwent endodontic access and were restored with composite resin, with cuspal coverage. Forty extracted human maxillary premolars were divided in 4 groups: I--intact teeth; II--teeth with endodontic access and MOD preparation, restored with composite resin, without cuspal coverage; III--teeth with endodontic access, MOD preparation and occlusal reduction, restored with composite resin, with cuspal coverage; IV--teeth with endodontic access and MOD preparation, without any restoration. The test specimens were submitted to compression test up to their fracture. The test of Turkey and the ANOVA analysis were used to compare and test the results. The teeth from group III (with cuspal coverage) presented with significantly greater resistance to fracture, when compared with those from groups II (restored without cuspal coverage) and IV (not restored). The composite restoration with cuspal coverage can be considered an alternative for endodontically treated premolars.

Bicuspid↗

Fracture strength of amalgam crowns with repaired endodontic access.

Endodontic therapy is accessed occlusally in posterior teeth, many of which have large, pre-existing amalgam restorations. These teeth are also commonly restored with an occlusal amalgam to repair the access opening. This study determined the fracture resistance of complex amalgam restorations that have repaired endodontic access compared with original, unrepaired, complex amalgams on endodontically-treated teeth. Two groups of 30 molars were used in the study. The first group was decoronated and received an endodontic access preparation. These teeth were restored using chamber retention and four TMS pins. The second group was decoronated and restored using pin retention. Later, they received an endodontic access through the restoration. The access was then repaired with amalgam. The samples were loaded in an Instron Universal Testing Machine until failure. The Group 1 samples failed at a mean force of 2297.5 N. The mean failure load for the samples in Group 2 was 1586.1 N. Student's t-test found this difference to be statistically significant. Endodontic access through an amalgam crown significantly compromises the fracture strength of the original restoration.

Dental Alloys↗

[The place of radiography in endodontic treatment carried out in general practice in Dakar].

An investigation conducted over dental surgeons of 52 dental offices in Dakar and it's near suburb (40 from private sector and 12 from public and quasi-public) has shown that the use of retro-alveolar radiography during endodontic treatment was not systematic, due to the price of retro-alveolar film, waste of time and relative facility of the endodontic treatment of monoradicular teeth. The preparatory negative is favored (32.70%) particularly by private dental surgeons, who use two retro-alveolar films for endodontic treatment: pre and post operative radiography (30%). The immediate post operator control is executed only in case of post-operator pains by public and quasi-public dental surgeons (16.67%) with one retro-alveolar film on average for the endodontic treatment; at term any radiographic control is done. Three retro-alveolar films per endodontic treatment were exceptionally used (9.61%) and offset incidences (15%) are not much used as well as support-films (angulators). The retro-alveolar radiography is still a reliable guide for a clinical success in endodontic treatment with a minimum of three retro-alveolar films and offset incidences.

Dental Pulp Cavity↗

The influence of coronal restoration type on the survival of endodontically treated teeth.

The aim of this study is to investigate the association between coronal restoration type and survival of endodontically treated teeth. A review was performed of treatment records of patients who had endodontic treatment performed in the Department of Restorative Dentistry, University Dental School & Hospital, Cork, Ireland during the period 1993-96. Demographic and dental factors such as age, gender, tooth type, coronal restoration type, and tooth status recorded at a review appointment were recorded. Tooth status at review was defined as 'tooth present' or 'tooth absent' based on the presence or absence of the endodontically treated tooth recorded in the treatment records at a review appointment held a minimum of one year following obturation of the root canal system. Of 176 teeth (166 patients) treated, survival of endodontically treated teeth was significantly more likely where restored with cast restorations (91.7%), amalgam restorations (86.5%), or composite restorations (83.0%), than teeth restored with temporary restorations (34.5%) (p<0.0001) (mean follow-up time 38 months, range 12-60 months). Survival of endodontically treated teeth was found to be associated with permanent coronal restorations. Loss of endodontically treated teeth occurred more often with those restored with temporary restorations (34.5%) than other restoration types (p<0.05).

Adolescent↗

Survival rate of endodontically treated teeth in relation to conservative vs post insertion techniques -- a retrospective study.

AIMS AND METHODS: The purpose of this retrospective, non-randomised cohort study was to evaluate the success rate of 775 endodontically treated teeth depending on the restoration type. A total of 508 patients with 775 endodontically treated teeth were examined during at least 12 months. The radiographic controls, time span between root canal filling and definitive restoration, restoration material type, inserted post system type and the occurrence of possible endodontically as well as restorative post-operative complications were recorded. RESULTS: 18.3% of the 775 investigated teeth were incisors and canines, 33.5% were premolars and 48.2% molars. Pre-fabricated and casted metal post systems were used only in 15.6% of the endodontically treated teeth (18.4% incisors and canines, 44.8% premolars, 36.8% molars). 6.6% of the teeth had endodontically related symptoms or severe complications, whereas in 13.2% of the teeth restored with metal posts showed complications, such as root or crown fractures. The Cox-Regression analysis showed that teeth restored with a post system had a statistically significant higher failure rate (p = 0.044) than those which had been restored without posts. CONCLUSIONS: The results showed a high success rate for endodontically treated teeth when the final restoration was placed within a short period of time (two weeks). A higher tooth loss was observed when metal post systems were employed suggesting that precaution is recommended when these types of posts are inserted.

Acrylic Resins↗

[Endodontic treatment and periapical health in patients of the Institute of Dentistry in Lódź].

OBJECTIVE: Retrospective assessment of periapical health in relation to sex, age and quality of root-canal treatment among adult patients of the Institute of Dentistry in Lódź. Orthopantomograms of 439 subjects were assessed considering the prevalence of endodontic treatment, technical quality of root-canal fillings and the state of periapical tissues. The assessment of orthopantomograms of 174 (39.6%) men and 265 (60.4%) women was carried out. A significant increase (p=0.016) in the mean number of endodontically treated teeth according to age (range from 1.4 in subjects under the age of 20 to 3.4 in those aged 70 years and over) and the mean number of teeth with periapical pathosis (from 0.9 to 2.4, respectively) (p=0.020) was observed. Of 10054 radiographically examined teeth 9.7% was treated endodontically, whereas, 5.5% exhibited periapical pathosis. The percentage of teeth with periapical lesions was significantly higher (p=0.015) in men (6.2%) as compared to women (5.0%). Periapical radiolucency occurred significantly more often (p=0.0001) in endodontically treated teeth (36.4% of cases) than in those with untreated root canals (2.1%). Teeth with inadequately filled root canals significantly more often revealed the presence of periapical pathosis (49.6%) in comparison to teeth with adequately filled root canals (4.2%). CONCLUSIONS: The prevalence of endodontic treatment and apical periodontitis increases with age. The prevalence of apical periodontitis depends on sex - periapical lesions were more often found in men. The quality of endodontic treatment significantly affects periapical health.

Adult↗