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At least 145 records · Page 8Linked to original sources

A ten-year analysis of demographic trends for cutaneous melanoma: analysis of 2501 cases treated at the University Department of Dermatology in Vienna (1990-1999).

BACKGROUND: The aim of the study is to provide recent demographic data on cutaneous melanoma in Austria. PATIENTS AND METHODS: Patients with primary cutaneous melanoma diagnosed between January 1, 1990 and December 31, 1999 were included in the analysis. Data were retrieved from the melanoma registry of the University Department of Dermatology in Vienna. RESULTS: In the observation period, 2501 cutaneous melanomas were diagnosed in 2427 patients (mean age: 55.4 yrs; 51.2% females). A total of 267 (10.7%) cutaneous melanomas were in situ, and 2234 (89.3%) were invasive. The median invasion thickness according to Breslow for invasive melanomas was 0.98 mm (25%-75% percentiles: 0.55-2.00 mm). We observed a significant trend towards thicker tumors with increasing age (p < 0.001). In patients less than fifty years of age, a significantly higher Breslow thickness was observed in men than in women (0.90 mm versus 0.80 mm, p = 0.03). The median Breslow thickness of invasive melanoma decreased from 1.20 mm in 1990 to 0.92 mm in 1999 (p for trend, < 0.001). Compared to women, men had melanomas more frequently on the back (43.8% versus 24.4%, p < 0.001). In women, melanomas were more frequently found on the lower legs than in males (21.5% versus 6.7%, p < 0.001). In a multivariate model, invasion thickness according to Breslow was the single most important predictor of survival. CONCLUSION: Our data confirm recent reports from other European countries with regard to the decline in tumor thickness of cutaneous melanoma. Our data also demonstrate a need for improving early diagnosis, particularly in certain subgroups of patients.

Adult↗

[Tempo and parity structure of Japanese fertility].

The present study is part of a larger project on the formal demographic analysis of Japanese fertility. It deals with the most elusive aspect of fertility, that is the tempo of fertility. The temporal aspect of fertility, particularly in terms of cohort fertility framework with speical reference to parity of women, has been emphasized by Whelpton and Ryder, but in the Japanese demography there have scarcely been studies of this aspect, probably due to lack of interest. In very recent years, however, interest has grown, reflecting the need for more accurate fertility projections in the future in connection with population projections. The present study is an application of life table techniques to explore the temporal aspect of fertility in Japan. 2 methods have been used. One is the age-marriage-parity specific net reproduction rate tables, which were first constructed by the senior author of this paper. The other is by Professor Chin Long Chiang at the University of California, Berkely. In the application of the former type, net reproduction rate tables were constructed for 3 dates -- 1970-71, 1975-76, and 1980-81. Through this method, it was demonstrated that recent fertility for the period 1980-81 was reduced, partly because of the decline in fertility in live-birth order of 1 and 2 among the relatively young ages up to 25 years old. On the other hand, for the ages up to 30 years old, some catching-up mechanisms took place. The 2nd method is by Chiang's new approach to the fertility table. According to his method, which was included in his new book entitled Life Tables and Its Applications, parity-oriented fertility tables have been constructed for the Japanese females for every year from 1971 through 1983, both inclusive. In these cases, denominator is for year z while numerator is concerned with yea z + 1. This method is particularly interesting since it can calculate waiting time for childbearing until the completion of family formation. Some of the findings indicated: 1) recent increases in both parity progession ratio and parity-specific fertility rate in low parity augur a future increase in fertility in the period measure in the near future; and 2) a shortening of the waiting time until the completion of family formation around 1981 and then the recovery of its lengthening in the years 1982 and 1983 suggest a recent trend of lengthening actual reproductive period which definitely contributes to an increase in fertility.

Asia↗

Construction of the new United Nations model life table system.

Previous systems of model life tables were based on empirical data from the now developed countries (the Coale and Demeny models) or, when patterns from less developed countries were included (the original UN set and the Lederman set), included data of poor or unknown quality. However, with the advent of new demographic techniques of data evaluation and of improved survey, census, and vital registration systems, it has become possible to construct a new model life table system based on reliable data from less developed countries and hence more applicable to demographic analysis within that milieu. The new UN model life tables are based on carefully evaluated age-sex specific mortality data found in developing countries. Analysis of these data indicated 4 major age patterns of mortality. These patterns have been labelled the Latin American pattern, the Chilean pattern, the South Asian pattern, and the Far Eastern pattern, according to the geographical region predominant in each pattern. An overall average pattern, labelled the general pattern, has also been constructed. Along with the model life tables themselves, the UN is also producing models of sex differences in life expectancy, single-year mortality, and stable populations. A manual of computer programs to facilitate use of these models is also being prepared.

Africa↗

[Clinical analysis and demographic characteristics of the sample of patients from the psychiatric outpatient clinic for chiidren and adolescents].

The article presents the demographic and clinical analysis of the sample of 679 persons in age under 20 who were out-patients in the Clinic of Child and Adolescent Psychiatry in Cracow (Poland) during one year. The clinical analysis takes into account among others the structure of diagnoses set according to ICD-10, the presence of additional diagnoses and risk factors, the way patients were referred to the out-patient units, and the sort of the care proposed. Most often syndromes from the section of emotional and behavioral disorders of childhood and adolescence (F90 - F98 in ICD-10) were recognised. On the level of separate disorders most popular in adolescents were anorexia nervosa (16%), adolescent depression (10%), acute psychoses (8%), and adjustment disorder (8%). In the discussion the results were referred to epidemiological community studies. It has been also noticed that the way symptoms of adolescence are understood is essential in psychiatric evaluation of adolescents.

Adolescent↗

Demographic-economic analysis in a multi-zonal region: a case study of Nordrhein-Westfalen.

"This paper develops a series of spatially-disaggregated demographic-economic models, based on an extended Leontief type input-output model. Travel between residence and place of work and residence and place of shopping is included in the models, and a detailed decomposition of a range of multipliers identified. A model explicitly involving travel to work is developed empirically for the state of Nordrhein-Westfalen in West Germany, and sets of multipliers presented which relate changes in demographic and economic variables in particular zones of the state with changes in economic output and employment-related variables in other zones."

Behavior↗

Input-output models for regional demographic-economic analysis: some structural comparisons.

"In this paper is presented a comparative survey of the many ways in which a static Leontief input-output model can be extended to include demographic-economic relationships. A family of ten input-output models is identified, with individual members defined according to their representation of household income, employment, and unemployment. Miyazawa's fundamental equation of income formation is generalised and used to establish structural relationships between the models, as reflected in income and employment impact-multipliers. Although the emphasis of the paper is theoretical, examples are given of the empirical application of existing models."

Demography↗

Demography of the Juang tribal population of Orissa.

Demographic analysis of genealogical data collected in 1954 for 23 Juang villages was undertaken employing indirect estimation techniques and computer projection methodology. Results indicated that this group did not feature the historically high fertility levels associated with Indian tribal groups, although fertility was higher than previously reported for the Juang. The population did feature a mortality differential, with worse mortality conditions than the Indian national population at this time. Reversed sexual mortality differentials, common in South Asian populations, were also present for the Juang. Computer projection investigation revealed a steadily growing population, in contrast to some Indian tribal groups faced with extinction.

Adolescent↗

A systematic demographic efficiency analysis of U.S. interstate population exchange, 1935-1980.

"Evolving patterns of population redistribution within the United States are examined for the period 1935 to 1980. The demographic efficiency measure is employed to assess the compensating or non-compensating nature of migration to and from each state. This measure is then extended in order to examine the entire system of state-to-state movement streams. Using the analytical technique of Q-analysis, systemic change is shown to have taken place. It is argued that the geographic pattern change reflects a nexus of economic and societal trends associated with post-industrialism."

Americas↗

An adaptation of the modified mini-mental state examination: analysis of demographic influences and normative data: the cache county study.

OBJECTIVES: To present a new version of the Modified Mini-Mental State Examination (3MS-R), provide normative information extending to individuals in the 10th decade, and examine the effects of demographic variables on test performance. BACKGROUND: The Modified Mini-Mental State Examination, based originally on the Mini-Mental State Examination, has been used to screen populations for dementia. Providing normative information and an analysis of demographic variables on test performance for this version would support broader use in clinical and other settings. METHODS: Two thousand, nine hundred thirteen elderly individuals determined to be free of dementia and other neurologic and psychiatric conditions served as subjects. An analysis of variance was conducted to examine the effects of age, gender, and education on test performance. Descriptive statistics (means, standard deviations, and percentile ranks) were calculated to summarize the range of normal performance. To examine the sensitivity/specificity of the suggested cut-off points at the 7th and 10th percentiles, two subsamples of elderly individuals, on whom clinical dementia assessments were available, were used to classify individuals with regard to dementia status. RESULTS: Lower age, higher education, and female gender were associated with higher 3MS-R scores. Gender effects were among the weakest, but most important at lower levels of education. Education effects were most prominent in the youngest age groups. Selection of a cut-off point at the 7th percentile revealed 69%-70% sensitivity for detecting dementia, and higher sensitivity for individuals in the youngest age groups. Specificity at this cut-off point was 89%. Raising the cut-off point to the 10th percentile improved sensitivity to 73%-76%, but reduced specificity to 85%-86%. CONCLUSION: We present a version of the Modified Mini-Mental State Examination that has demonstrated utility in screening a population for dementia. An analysis of normative information and the effects of demographic influences suggest that the 7th percentile cut-off point performs very well in detecting dementia in 65-79-year-old individuals but less well for individuals in their 80s and 90s. To increase the sensitivity of the 3MS-R to detect dementia or other forms of cognitive impairment, particularly among the "old-old," the test user may wish to raise the cut-off point for impairment in some demographic groups or to supplement the test with additional cognitive measures.

Aged↗

Risk factors for high-grade cervical intraepithelial neoplasia in patients with mild cytological dyskaryosis: human papillomavirus testing versus multivariate tree analysis of demographic data.

The objective of this study was to compare the use of molecular hybridization by hybrid capture methodology for human papillomavirus (HPV) with the use of demographic and lifestyle variables as intermediate triage in patients with cytological mild dyskaryosis. The study was designed as a prospective study using regression tree analysis of demographic data in consecutive patients who were subjected to colposcopic evaluation at the colposcopy clinic at the First Department of Obstetrics and Gynaecology, University of Milan (Milan, Italy). A total of 177 women were subjected to colposcopy because of a single routine Pap smear showing mild dyskaryosis. A structured interview, sampling for HPV testing for the detection of viral DNA by hybrid capture methodology, and colposcopic evaluation with cervical biopsies were performed for each subject. The accuracies of molecular hybridization for HPV and of the classification model based on the demographic and lifestyle variables in predicting patients with histologically high-grade cervical intraepithelial lesions were measured. The classification model based on the demographic and lifestyle variables showed comparable results with molecular hybridization for HPV (specificity, 0.75 versus 0.73; sensitivity, 0.61 versus 0.67, respectively). The use of demographic and lifestyle variables appears to be a simple and economic possibility for triaging patients with mild dyskaryotic smears in a screening program.

Adult↗

[Demographic-statistical analysis of pharmacotherapy with emphasis on the geriatric population].

The present paper is a contribution to the field of population pharmacoepidemiology and presents an analysis of the effect of the determinant of age on the magnitude of requirements for medicines, particularly with regard to gerontological population. The paper reports both demographic and pharmacoepidemiologic analysis of pharmacotherapy and formulates a trend of development in connection with expected demographic ageing of the Slovak population. The results reported in the paper document the demographic-health background of pharmacotherapy and point to some population connections of it.

Aged↗

Genetic analysis reveals demographic fragmentation of grizzly bears yielding vulnerably small populations.

Ecosystem conservation requires the presence of native carnivores, yet in North America, the distributions of many larger carnivores have contracted. Large carnivores live at low densities and require large areas to thrive at the population level. Therefore, if human-dominated landscapes fragment remaining carnivore populations, small and demographically vulnerable populations may result. Grizzly bear range contraction in the conterminous USA has left four fragmented populations, three of which remain along the Canada-USA border. A tenet of grizzly bear conservation is that the viability of these populations requires demographic linkage (i.e. inter-population movement of both sexes) to Canadian bears. Using individual-based genetic analysis, our results suggest this demographic connection has been severed across their entire range in southern Canada by a highway and associated settlements, limiting female and reducing male movement. Two resulting populations are vulnerably small (< or =100 animals) and one of these is completely isolated. Our results suggest that these trans-border bear populations may be more threatened than previously thought and that conservation efforts must expand to include international connectivity management. They also demonstrate the ability of genetic analysis to detect gender-specific demographic population fragmentation in recently disturbed systems, a traditionally intractable yet increasingly important ecological measurement worldwide.

Animal Migration↗

Living arrangements of older adults in the developing world: an analysis of demographic and health survey household surveys.

OBJECTIVES: This study examines living arrangements of older adults across 43 developing countries and compares patterns by gender, world regions, and macro-level indicators of socioeconomic development. METHODS: Data are from Demographic and Health Surveys. The country is the unit of analysis. Indicators include household size, headship, relationship to head, and coresidence with spouse, children, and others. Unweighted regional averages and ordinary least-squares regressions determine whether variations exist. RESULTS: Average household sizes are large, but a substantially greater proportion of older adults live alone than do individuals in other age groups. Females are more likely than males to live alone and are less likely to live with a spouse or head of a household. Heading a household and living in a large household and with young children is more prevalent in Africa than elsewhere. Coresidence with adult children is most common in Asia and least in Africa. Coresidence is more frequent with sons than with daughters in both Asia and Africa, but not in Latin America. As a country's level of schooling rises, most living arrangement indicators change with families becoming more nuclear. Urbanization and gross national product have no significant effects. DISCUSSION: Although living arrangements differ across world regions and genders, within-region variations exist and are explained in part by associations between countrywide levels of education and household structure. These associations may be caused by a variety of intermediating factors, such as migration of children and preferences for privacy.

Adolescent↗