Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Community Detection”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources
PubMed2005

Colorectal cancer detection in a rural community. Development of a colonoscopy screening program.

PROBLEM BEING ADDRESSED: Colorectal cancer (CRC) is a substantial cause of death and morbidity in Canada. Endoscopy screening by colonoscopy has been recommended, but widespread implementation is impossible because it is difficult to obtain, especially in rural areas. OBJECTIVE OF PROGRAM: To screen for CRC safely and effectively using colonoscopy performed by non-specialist endoscopists in rural areas. PROGRAM DESCRIPTION: Health providers and community organizations were informed about the screening program. Patients between the ages of 50 and 75 and those at high risk of CRC based on family history were screened. Measures of safety and effectiveness were monitored. In 2 years of screening, one of 152 patients was found to have CRC, and 23.7% had adenomatous polyps. There were no complications. Rates of CRC and adenoma detection and cecal intubation were similar to rates found in other screening studies. CONCLUSION: It was not difficult to design and implement a CRC screening program in our small rural community. Colonoscopies performed by family physicians have been effective, and there have been no serious complications.

Aged↗
PubMed2003

Early detection of kidney disease in community settings: the Kidney Early Evaluation Program (KEEP).

BACKGROUND: Early identification of persons at risk for kidney disease provides an opportunity to prevent or delay its progression and decrease morbidity and mortality. Our hypothesis was that implementation of a targeted screening program in communities with high-risk populations would detect previously unidentified persons with or at high risk for chronic kidney disease (CKD) with a prevalence that exceeds that predicted for CKD in the general population. METHODS: Persons with hypertension or diabetes or a first-order relative with hypertension, diabetes, or kidney disease were screened for kidney disease risk factors. Blood pressure, blood glucose level, serum creatinine level, hemoglobin level, microalbuminuria, hematuria, pyuria, body mass index, and estimated glomerular filtration rate (EGFR) were evaluated. RESULTS: Six thousand seventy-one eligible persons were screened from August 2000 through December 2001: of these persons, 68% were women, 43% were African American, 36% were white, 10% were Hispanic, and 5% were Native American. Most reported high-school education or more (84%) and health insurance coverage (86%). Twenty-seven percent met the screening definitions for diabetes; 64%, for hypertension; 29%, for microalbuminuria; 8%, for anemia; 18%, for hematuria; 13%, for pyuria; 5%, for elevated serum creatinine level; 16%, for reduced EGFR; and 44%, for obesity. Among participants without a reported history of specified conditions, screening identified 82 participants (2%) with diabetes, 1,014 participants (35%) with hypertension, 277 participants (5%) with elevated serum creatinine levels, 839 participants (14%) with reduced EGFRs, and 1,712 participants (29%) with microalbuminuria. Thirty-five percent of participants with a history of diabetes had elevated serum glucose levels at screening (> or =180 mg/dL [10 mmol/L]), and 64% with a history of hypertension did not have blood pressure controlled to less than 140/90 mm Hg. Only 18% of participants with a history of diabetes and 31% with a reduced EGFR had blood pressure controlled to less than 130/80 mm Hg and less than 135/85 mm Hg, respectively. CONCLUSION: Targeted screening is effective in identifying persons with previously unidentified or poorly controlled kidney disease risk factors, as well as persons with a moderately decreased EGFR.

Adolescent↗
PubMed1986

Community-wide prevention strategies: evaluation design of the Minnesota Heart Health Program.

The Minnesota Heart Health Program (MHHP) is a community-based research and demonstration program designed to accelerate population-wide changes in coronary risk factors and disease. MHHP is on-going in three pairs of communities in Minnesota, North and South Dakota. To strengthen inference of program effects, its basic design involves elements of control, repetition, sensitive trend measurements and evaluation of the effects of program components. Its evaluation design is presented here as a comprehensive measurement system for disease endpoints, risk factor levels and efficacy of specific educational programs. The MHHP design is able to compare risk factor levels and mortality rates between education and comparison communities. MHHP statistical power is sufficient to detect community-wide changes of public health import. Early results show comparability of education and comparison communities for most variables. Widespread community awareness of and participation in MHHP programs is reported.

Adult↗
PubMed2005

Utility and diagnostic accuracy of sonography in detecting appendicitis in a community hospital.

OBJECTIVE: The purpose of this study was to determine the utility and accuracy of sonography in diagnosing acute appendicitis in patients with suspected acute appendicitis in a general community hospital. MATERIALS AND METHODS: All reports relating to appendicitis were retrospectively obtained from archived transcription reports of nine radiologists from a geographically constrained hospital between December 1999 and December 2003 by a search on the keyword "appendicitis." These files were correlated with the histopathology reports from surgical appendectomy or findings from clinical follow-up during the same period. A survey eliciting the views of five local surgeons on the utility of sonography for the detection of acute appendicitis was also collected. RESULTS: Sonography reports for 667 patients (mean age, 34 years; range, 6-93 years) were obtained. Of these, a total of 174 had pathologically proven appendicitis and 145 had positive findings for appendicitis on sonography. The accuracy was 92%; sensitivity, 83%; and specificity, 95%. The positive predictive value was 86%, and the negative predictive value was 94%. Three of the five surveyed surgeons indicated they used sonography less than 25% of the time, with none using it more than 75%. CONCLUSION: The sensitivity, specificity, accuracy, and positive and negative predicative values of sonography performed by general radiologists in a community hospital are comparable to statistics quoted in the literature for academic institutions. The most common error was the tendency to misclassify appendixes under 6 mm. Most surgeons surveyed stated their use of sonography would increase if sonography yielded a sensitivity and specificity of 85% or greater.

Acute Disease↗
PubMed2006

A case study of an emerging community-based early hearing detection and intervention program: part II. Team building with otolaryngologists and pediatricians using a survey approach.

PURPOSE: Physicians are vital team members of early hearing detection and intervention programs (EHDIPs), particularly in encouraging parents to comply with recommendations for follow-up services for their infants in universal newborn hearing screening programs (UNHSPs). This study describes a survey approach to help audiologists partner with otolaryngologists and pediatricians in EHDIPs. METHOD: We developed and mailed a 19-item questionnaire to all 12 otolaryngologists and 66 pediatricians potentially involved in a community-based EHDIP. The questionnaire assessed respondents' demographic data and knowledge of, experiences with, and attitudes toward the service-delivery continuum of UNHSPs. RESULTS: The overall response rate was 45%; all 12 otolaryngologists responded (100%; data from 7 were analyzed), and 23 pediatricians responded (34.8%; all were analyzed). Generally, they were positive toward and knowledgeable about UNHSPs and believed that (a) parent/infant bonding is unaffected by screening, (b) hearing reevaluations following medical services are important, (c) audiologists perform their role adequately, (d) it is important that hearing losses be identified and interventions begun before infants reach 6 months of age, (e) UNHSPs deserve funding, and (f) their role is important, but the physicians also wanted improvements in parent education and referral/follow-ups. CONCLUSION: The survey method was effective in identifying participating physicians' informational needs and attitudes toward UNHSPs, and in designing outreach programs for them.

Attitude of Health Personnel↗
PubMed1989

Community radon awareness and detection: a model program.

A project for increasing public awareness of radon as an environmental hazard was carried out in south central Wisconsin and northwest Illinois using local medical resources. In Wisconsin counties, measured radon levels were equal to or greater than those obtained by a 1986-87 EPA survey. More than 30% of the buildings surveyed exceeded 4 pCi/L, and 10% exceeded 10 pCi/L. Results in Illinois were similar to those from contiguous areas of Wisconsin. In view of the known link between radon-222 exposure and lung cancer, we urge that similar projects be performed by other medical communities across the state and nation.

American Medical Association↗
PubMed2001

Assessing hypertension management in the community: trends of prevalence, detection, treatment, and control of hypertension in the MONICA Project, Augsburg 1984-1995.

OBJECTIVE: To assess trends in prevalence and detection, treatment and control of hypertension in a German population between 1984 and 1995. SETTING AND PARTICIPANTS: Independent random samples of the population were examined in cross-sectional surveys with identical methods in 1984/85 (age range 25 to 64 years, n = 4022 participants), 1989/90 (age range 25 to 74 years, n = 4940) and 1994/95 (age range 25 to 74 years, n = 4856). MAIN OUTCOME MEASURES: Prevalence of hypertension and proportions of hypertensives detected, treated and controlled. Hypertension was defined as blood pressure above 140/90 mm Hg or taking antihypertensive medication. RESULTS: The prevalence of hypertension did not change significantly over the 10 years (25--64 years, age-standardised 1984/85: 37.8% in men and 24.6% in women; 1994/95: 39.3% and 24.8%, respectively). Rates of detection, treatment and control of hypertension did not change much either. Of all hypertensives in 1994/95, 54% were detected in men and 64% in women, the treatment rates were 23% and 32%, and the proportions of those with controlled hypertension (below 140/90 mm Hg with treatment) were as low as 7% and 13%, respectively. Rates were higher in the older age groups, however, control rates never exceeded 20% at any age. CONCLUSIONS: Despite considerable changes in the pharmacological treatment of hypertension there was a disappointing stagnation with regard to the management of this important risk factor in the community. The reasons for this unfavourable trend need clarification and appropriate public health action. Journal of Human Hypertension (2001) 15, 27-36

Adult↗
PubMed2004

Community trends in the early detection of breast cancer in Wisconsin, 1980-1998.

BACKGROUND: Early detection of breast cancer is an important public health goal. Rates of early detection have increased over the past several decades, contributing to recent declines in mortality. Despite these overall trends, however, some populations have experienced less progress than others. METHODS: The rates of early detection, measured as the percentage of breast cancers diagnosed as breast carcinoma in situ, were calculated using data from Wisconsin's population-based tumor registry from 1980 to 1998. Trends in breast cancer (percent diagnosed in situ) were examined over time by socioeconomic characteristics of ZIP code of residence, using census data. RESULTS: The percentage of breast cancer cases that were breast carcinoma in situ was more than five times greater in the later period (1994-1998) (13.9%), compared with the early period (1980-1984) (2.6%). In the middle period (1987-1991), breast cancer was diagnosed as breast carcinoma in situ about one-third less frequently among women in areas with the lowest urbanization, median family income, and percent educated beyond high school, compared with communities with the highest levels of these variables. Recently disparities in early detection rates by community income and education indicators declined slightly, whereas disparities in percent of breast carcinoma in situ by urbanization did not. CONCLUSIONS: Communities with lower levels of income, education, and urbanization lagged in the early detection of breast cancer during the 1980s and, despite some progress during the 1990s, continue to be underserved. Women in these communities should be targeted for interventions to improve the early detection of breast cancer.

Breast Neoplasms↗
PubMed1997

Detection and management of pneumonia by community health workers--a community intervention study in Rehri village, Pakistan.

This community based, case management intervention study was done to assess the effectiveness of Community Health Workers (CHWs) in case detection and management of pneumonia in children under five years of age. Twenty-two volunteers (school teachers and students) were selected as CHWs from Rehri village, in Sindh, Pakistan and trained on World Health Organization (WHO) recommended National/Acute Respiratory Tract Infection (ARI) guidelines at the Department of Paediatrics, Dow Medical College, Civil Hospital, Karachi. The CHWs had no prior health education. The intervention was the use of CHWs to detect and manage pneumonia in children under five years of age in Rehri village. Two medical officers supervised the post-training activities of CHWs in the village during the study period. Between December, 1992 and May, 1993, 442 episodes of pneumonia (very severe disease 10, severe pneumonia 54 and simple pneumonia 378) were detected and managed by trained CHWs. The medical officers agreed with the CHWs for classification and treatment in 356 (81%) cases. This study suggests that in areas where there is a shortage of trained health care professionals, educated community members such as school teachers can be trained to detect and manage pneumonia in their community.

Case Management↗
PubMed1998

Dermatophagoides sp. and IgE anti-D. pteronyssinus and D. farinae detection in a Venezuelan community at more than 2000 m above the sea level.

BACKGROUND: It has been reported that the concentration of Dermatophagoides sp. population, the main trigger of asthma in sensitized atopic subjects, is inversely related with altitude and probably directly with humidity and that this population are scarcely found over 1750 m above sea level. OBJECTIVE: We studied the presence of Dermatophagoides sp. in a Venezuelan community between 2040 and 2600 m above sea level, and also the IgE response to D. pteronnyssinus and D. farinae in atopic subjects living on that region. METHODS: The presence of Dermatophagoides sp. was determined by microscopic identification of mites in dust, obtained by brushing the mattresses surface in 93 randomly selected houses between 2040 and 2600 m above sea level. The indoor relative humidity was also measured. The specific IgE serum levels were studied in 65 subjects classified as asthmatics, allergic non-asthmatics and non-allergic. RESULTS: A mean concentration of 188 mites/g of room dust was determined in 82.4% of houses with an indoor relative humidity ranging from 89% and 92% independently of altitude. The density of Dermatophagoides sp. was sufficiently high to sensitize the atopic subjects, IgE levels were 6.8 PRU mean value for asthmatic, against 0.38 PRU in non-atopic. CONCLUSIONS: We conclude that: (a) Dermatophagoides sp. can be found up to 2600 m above sea level in a Venezuelan neotropical region where a high indoor relative humidity is characteristic of most dwellings; (b) sensitization by D. pteronyssinus and D. farinae were demonstrated in atopic subjects resident at that region.

Allergens↗
PubMed2005

Design of long oligonucleotide probes for functional gene detection in a microbial community.

MOTIVATION: Analysis of the functions of microorganisms and their dynamics in the environment is essential for understanding microbial ecology. For analysis of highly similar sequences of a functional gene family using microarrays, the previous long oligonucleotide probe design strategies have not been useful in generating probes. RESULTS: We developed a Hierarchical Probe Design (HPD) program that designs both sequence-specific probes and hierarchical cluster-specific probes from sequences of a conserved functional gene based on the clustering tree of the genes, specifically for analyses of functional gene diversity in environmental samples. HPD was tested on datasets for the nirS and pmoA genes. Our results showed that HPD generated more sequence-specific probes than several popular oligonucleotide design programs. With a combination of sequence-specific and cluster-specific probes, HPD generated a probe set covering all the sequences of each test set. AVAILABILITY: http://brcapp.kribb.re.kr/HPD/

Algorithms↗
PubMed2005

Community-acquired bacteria frequently detected by means of quantitative polymerase chain reaction in nosocomial early-onset ventilator-associated pneumonia.

OBJECTIVE: To test whether real-time polymerase chain reaction allows for rapid quantitative detection of Streptococcus pneumoniae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila in bronchoalveolar lavage fluids and to determine the prevalence of these pathogens in nosocomial ventilator-associated pneumonia. DESIGN: Prospective epidemiologic study applying a new molecular biology-based diagnostic tool during a 27-month period. SETTING: Three medical intensive care units of a tertiary care university hospital. PATIENTS: One hundred patients suffering from nosocomial ventilator-associated pneumonia, hospitalized for > or =14 days, intubated for reasons other than pneumonia, and mechanically ventilated for >48 hrs. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: S. pneumoniae, M. pneumoniae, and C. pneumoniae were detected in bronchoalveolar lavage fluids of 100 patients in 20 (20%), three (3%), and two (2%) cases, respectively. There of 17 (71%) revealed no growth or no significant growth by conventional culture. In one patient, S. pneumoniae and M. pneumoniae were detected simultaneously. Corresponding colony-forming units/mL were partly up to 10 CFU/mL with Gram stainings showing signs of acute inflammation in 80%. A significant temporary correlation between the number of days on ventilator, development of nosocomial pneumonia, and the frequency of detection of these pathogens was found for day 4. CONCLUSIONS: S. pneumoniae, M. pneumoniae, and C. pneumoniae should be considered as causative agents in critically ill patients who develop early-onset nosocomial ventilator-associated pneumonia. Thus, empirical antimicrobial regimens should cover S. pneumoniae, Chlamydia, and Mycoplasma alike. Quantitative polymerase chain reaction is a fast diagnostic tool allowing for detection of these bacteria within 3 hrs in pretreated patients.

Adult↗
PubMed1999

Medication management capacity in highly functioning community-living older adults: detection of early deficits.

OBJECTIVE: The Drug Regimen Unassisted Grading Scale (DRUGS) was developed and employed in testing the hypothesis that the inability to take medication independently may correlate with the presence of cognitive impairment. DESIGN: Cross-sectional study. SETTING: Two continuing care retirement facilities in the Greater Boston area. PARTICIPANTS: The study population included outpatients > or = 70 years old. MEASUREMENTS: We developed a novel performance-based measure, the DRUGS tool, involving a step-wise progression of four tasks: (1) identification; (2) access; (3) dosage; and (4) timing. RESULTS: Fifty-nine participants aged 84.2 +/- 5.1 years (mean +/- SD) completed the study. The DRUGS tool score was inversely related to age (r = -.41, P = .001). Compared with independent-living, residence in assisted-living was associated with lower DRUGS tool scores (82.0% vs 93.8%, P = .009). The DRUGS tool score was associated with self-reported Medication Management capacity (94.8% able vs 86.2% unable to take medications independently by self-report, P = .047). Both DRUGS tool score and self-reported Medication Management capacity were associated with MMSE (P = .0008 and P = .044, respectively). The multivariate model, with DRUGS tool Summary Score as the dependent variable, adjusted for age and sex, included MMSE (P = .023) and self-reported IADL (P = .038). CONCLUSION: There is an association between performance on the DRUGS tool and level of cognitive function. The DRUGS tool represents a unique individualized, yet standardized, assessment of the ability to function independently for ambulatory older persons. It may be useful for identifying those highly functioning older persons, at an early phase of cognitive decline, in whom targeted intervention would likely be most effective and efficient.

Activities of Daily Living↗
PubMed1980

Use of a self-report symptom scale to detect depression in a community sample.

The authors gave the CES-D, a self-report depression symptom scale, to 515 people drawn from a longitudinal community survey. The subjects were also interviewed using the Schedule for Affective Disorders and Schizophrenia (SADS). From the information collected on the SADS, the subjects were given diagnoses based on Research Diagnostic Criteria. The results indicate a modest relationship between self-reported symptoms of depression and the diagnosis of a major or minor depression. However, the groups defined as "cases" by such reports also include many people with other diagnoses or with no diagnoses at all. Thus, symptom scales are useful for the screening of depressed persons in research studies but are only rough indicators of clinical depression in the community.

Adolescent↗
PubMed2003

'You can't tell by looking': pilot study of a community-based intervention to detect asymptomatic sexually transmitted infections.

Innovative and non-stigmatizing interventions are required to reduce ethnic inequalities in rates of sexually transmitted infections among young people. We therefore designed an intervention, 'You can't tell by looking,' which combined health promotion with testing for gonorrhoea and chlamydia using nucleic acid amplification technology and treatment and partner notification delivered in the non-clinical settings. One hundred and eighty-one participants were seen in 13 sessions in local further education colleges. Forty-three percent of participants were from Black Caribbean or Black Other ethnic groups and 39% were Black African: 125 of 181 participants were sexually active and 109 of these (87%) provided a urine specimen. 10/109 (9.2%, 95% confidence interval 4.5-16.2%) samples were confirmed positive for Chlamydia trachomatis and two were also positive for Neisseria gonorrhoeae. Only 7% of those tested found it embarrassing. The intervention was both feasible and acceptable to young people. It could be tested in a wider variety of non-clinical settings and evaluated in a cluster randomized trial.

Adolescent↗