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Surgical complications of ascariasis.

Over the past 25 years (1963-1988), a total of 311 children under 12 years of age were admitted to the Pediatric Surgical Service of the San Vicente de Paúl University Hospital, Medellín, Colombia, with complications resulting from infection with Entamoeba histolytica or Ascaris lumbricoides. In this group, the abdominal complications produced by ascariasis numbered 145, and included intestinal obstruction (n = 107), perforation of the appendix (n = 10), and migration of the parasite to the biliary tree or to the peritoneal cavity (n = 28). Evaluation of the living conditions of a significant subgroup of our patients confirms that intestinal parasitism is an endemic condition prevailing in nations that exhibit deep social and economic imbalance, where large sectors of the population remain deprived of the basic services of education, health, housing, and recreation. Massive infestation in children may give rise to grave complications that demand expert surgical care. Third World surgeons practicing in general hospitals that take care of patients of low economic capacity are usually familiar with the diagnosis and management of this pathology; surgeons who practice in the industrialized nations will only occasionally face such problems. The greater mobility of today's societies and the rather massive migrations that take place in current times have resulted in an increasing incidence of these entities in the hospital populations of the large urban centers of these nations. It is for the surgeons practicing in such centers that the information presented herein may be of greater value.

Appendicitis↗

Ascariasis of the gastrointestinal tract.

The radiographic findings and complications of Ascaris lumbricoides infection of the gastrointestinal tract are presented. Since the clinical symptoms of ascariasis are usually vague or nonspecific, the radiologist may be in a position to play a major role in the proper diagnosis of this disease.

Ascariasis↗

Endoscopic retrograde cholangiopancreaticographic features of pancreaticobiliary ascariasis.

Endoscopic retrograde cholangiopancreaticographic features of ascariasis involving the biliary system (56) and pancreatic duct (4) in 60 consecutive patients have been analyzed and their various radiologic appearances described. Ascaris not only presents as a smooth linear filling defect, as commonly described in the literature, but also in a variety of other shapes like parallel smooth filling defects, curves, and loops crossing the hepatic ducts transversely. They can also cause dilatation of the ducts that, depending upon their number and duration of stay, is statistically significant and reversible. Ascaris can also invade the pancreatic duct causing chronic pancreatitis.

Ascariasis↗

Biliary ascariasis: surgical aspects.

Presentation and management of 204 patients with biliary ascariasis seen over a period of 5 years is reported from a highly endemic area of Kashmir. Ultrasonography is the single most useful means of diagnosis. Endoscopic retrograde cholangiopancreatography is extremely helpful. Most patients respond to conservative management and around one-fifth of all patients require surgery.

Adolescent↗

Sonographic diagnosis of biliary ascariasis.

In an 11.5-year-old boy with obstructive jaundice sonography revealed a worm-like structure within the dilated biliary tree. Cross-section showed a bull's eye configuration, whereas longitudinal planes demonstrated an echogenic strip with a central longitudinal anechogenic tube. Diagnosis of ascariasis was established by identification of ascarid eggs in the stool. After anthelminthic treatment several ascarid worms were excreted with the stool.

Ascariasis↗

Acalculous cholecystitis: ascariasis as an unusual cause.

Migration of roundworms into the biliary tree is a well-known complication of Ascaris lumbricoides infestation of the intestine. Massive infestation of the hepato-biliary tract is uncommon but can lead to complications if not treated. Here, we report two cases of acalculous cholecystitis caused by ascariasis.

Adult↗

An unusual cause of haemobilia: biliary ascariasis.

A case of haemobilia following biliary ascariasis is presented. Angiography confirmed an aneurysm of the left hepatic artery, which was successfully embolised. The patient made an uneventful recovery.

Aneurysm, False↗

Biliary ascariasis: ultrasonography, endoscopic retrograde cholangiopancreatography, and biliary drainage.

Roundworms migrating into the biliary tract are a relatively common cause of biliary symptoms in areas where the parasite is endemic. Visualization of worms by conventional radiologic methods is often unsatisfactory, whereas ultrasonography offers a rapid, safe, and noninvasive approach to the diagnosis. Using real-time ultrasonographic scanning we demonstrated for the first time the characteristic morphology of the worms in a patient with biliary ascariasis. In addition, the motility of the worms in the biliary tract could be confirmed. Ultrasonography is also a convenient method for the follow-up of patients. Endoscopic biliary drainage and instillation of piperazine citrate through a nasobiliary drain is a logical therapy and was used successfully in this patient.

Adult↗

Intestinal perforation in ascariasis--case reports.

Two cases of intestinal perforation in association with ascariasis are described. In both cases adult ascarids were found either in the gut or lying free in the peritoneal cavity. Neither patient had typhoid fever, one had Hodgkin's lymphoma. The authors believe that the perforation were directly caused by the ascarids. Both patients died.

Adult↗

Ascariasis and acute otitis media.

Ascaris lumbricoides has rarely been implicated in the causation of middle ear disease. An infant who developed acute suppurative otitis media while on antibiotics for an upper respiratory tract infection and who extruded an ascaris worm from the ear is presented. The otitis media subsequently resolved. Our understanding of the pathophysiology of ascariasis in the eustachian tube and middle ear is discussed.

Acute Disease↗

Ascariasis pneumonitis: a potentially fatal complication in smoke inhalation injury.

Ascaris pneumonitis in areas of endemic infestation is considered a benign condition. Smoke inhalation with any burn injury can be potentially fatal. A heavy infestation of Ascaris could further exacerbate the smoke-induced lung injury. After ingested eggs hatch in the small intestine, the larvae penetrate the mucosa and invade the blood stream and are then carried to the lungs. The larvae break out into the aveolar spaces as they are too large to cross the capillary bed and are carried up the bronchial tree and eventually swallowed. This study describes three cases of Ascaris infection in thermally injured children. While the burns were < 30 per cent total body surface area, two patients who were injured in the same fire had a further complication of smoke inhalation which necessitated sophisticated therapy in order to promote survival. All patients were treated initially with Vermox. The one patient without smoke inhalation did not develop ascariasis pneumonitis even with positive stool samples and was discharged with no complications, whereas the two with smoke inhalation developed severe pneumonitis. One patient was placed on ECMO and did not receive a full course of the Vermox treatment. This patient died after several weeks of ECMO treatment. The third patient received a full course of Vermox, slowly recovered, and went home. Supportive therapy only is recommended during the lung migration phase of the Ascaris lifecycle. We feel that continuation of chemotherapy (Vermox) would have been beneficial in the fatal case based on the survival of the second patient.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Worm extraction and biliary drainage in hepatobiliary and pancreatic ascariasis.

From December 1989 to March 1992, 50 (32%) of 156 patients with hepatobiliary and pancreatic ascariasis underwent various endoscopic interventional procedures. Endoscopic intervention was performed when patients did not respond to energetic symptomatic treatment within the first few days of hospitalization (n = 45) or when worms had not moved out of the ducts into the duodenum at 3 weeks (n = 5). Worm extraction was successful in all 18 patients from the ampullary orifice and in 34 (89.5%) of 38 patients from the bile or pancreatic duct. In five patients with pyogenic cholangitis, endoscopic nasobiliary drainage was performed to decompress the bile ducts. After worm extraction/nasobiliary drainage, 41 (91%) of the 45 patients with biliary disease (n = 42) or acute pancreatitis (n = 3) had rapid relief of symptoms. Three patients developed complications related to endoscopy, including cholangitis (n = 2) and hypotension (n = 1).

Adult↗

Massive gastrointestinal bleeding in infants with ascariasis.

Although infestation with Ascaris lumbricoides causes various intestinal complications, massive gastrointestinal bleeding is rare. The authors report on 2 infants who presented with massive hematemesis. In the first patient, a gastroduodenoscopy was performed. Roundworms were found adhering to an oozing duodenal ulcer. Duodenal perforation occurred after extraction of the parasites. The second case was hematemesis together with peritonitis. Exploration found volvulus and a gangrenous segment of the distal ileum. Both infants previously passed roundworms with their stool. The authors conclude that the intestinal ascariasis can be a cause of massive gastrointestinal bleeding, especially in temperate and tropical countries.

Animals↗

Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.

The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm, are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in a less developed country is likely to be parasitised with at least one, and in many cases all three soil-transmitted helminths, with resultant impairments in physical, intellectual, and cognitive development. The benzimidazole anthelmintics, mebendazole and albendazole, are commonly used to remove these infections. The use of these drugs is not limited to treatment of symptomatic soil-transmitted helminth infections, but also for large-scale prevention of morbidity in children living in endemic areas. As a result of data showing improvements in child health and education after deworming, and the burden of disease attributed to soil-transmitted helminths, the worldwide community is awakening to the importance of these infections. Concerns about the sustainability of periodic deworming with benzimidazole anthelmintics and the emergence of resistance have prompted efforts to develop and test new control tools.

Animals↗

Ascariasis mimicking an acute abdomen.

Infection with the roundworm Ascaris lumbricoides is common in children and may mimic an acute abdomen. The cases of two pediatric patients who presented to the emergency department with signs and symptoms of a surgical abdomen are presented to highlight the presentation of this infection. Both cases were diagnosed by physical examination and radiographs and were treated successfully without surgical intervention. These cases illustrate the need for heightened awareness by the emergency physician of ascariasis in the differential diagnosis of acute abdomen.

Abdomen, Acute↗

Cardiac tamponade in a child with ascariasis.

Ascaris infection, when severe, may manifest with constitutional symptoms. The parasites penetrate the intestinal walls, reach the venules and lymphatics and, through the portal circulation, may affect the heart. To the best of our knowledge, involvement of the pericardium has yet to be reported. We describe here a case of severe pericardial effusion and cardiac tamponade in a child with ascariasis.

Ascariasis↗

[Ascariasis in Western Africa. Epidemiological review].

This paper draws, on the basis of available published reports, an outline of the epidemiological distribution of ascariasis in West Africa. This parasitic disease is easily transmitted in all humid areas which receive more than 1,400 mm rainfall every year. The endemicity pattern is typical of a contamination of the household environment. On the contrary, it is absent, with few exceptions, from a larger part of the region where drier conditions, combined with a series of specific socio-cultural factors, prevent the transmission from being anything else but sporadic. However, the author, although he recognizes that the maintenance of a short living parasite in a population is problematical under sporadic transmission conditions, warns that urban development in the future may very well result in a rapid spread of infections with ascaris.

Africa, Western↗

Ascariasis. An infection to watch for in immigrants.

Infection with Ascaris lumbricoides, a roundworm that invades the human digestive tract, affects about 25% of the world's population. Manifestations of ascariasis vary and include constitutional symptoms, particularly pulmonary and gastrointestinal complaints. Complications include pneumonitis, intestinal obstruction, and damage to vital organs. Diagnosis is made in most cases by sampling stool for ova and parasites. Treatment with an anthelmintic agent is usually effective in mild cases, and prognosis is excellent. More severe infection may cause significant morbidity and require surgical intervention.

Animals↗