[Vacuum and electrovacuum methods in the treatment of chronic recurrent inflammation of the adnexa uteri].
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Adult↗
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Results for “ADNEXA UTERI”
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[Rehabilitation of patients operated on for saccular inflammatory formations of the adnexa uteri].
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Adult↗
[An intensive regimen of supersonic-frequency-current therapy in chronic inflammation of the adnexa uteri].
As shown by clinical, electrophysiological and hormonal examinations of 34 patients with chronic inflammation of the uterine appendages and control subjects, the disease treatment with intensive low-frequency current has no negative effects on cardiovascular and endocrine systems, improves function of the reproductive system. Intensive low-frequency currents are believed to be a useful modality in management of chronic genital inflammation.
Adolescent↗
[The treatment results in inflammatory diseases of the adnexa uteri with different methods of using sinusoidal modulated currents].
Electrophoresis of 2% solution of sodium salicylate was made by impulse currents (SMC) according to transcutaneous, intracavitary, intraorgan techniques in 90 gynecological patients with nonspecific acute and chronic affections of the uterine appendages. Echography proved high efficacy of the intracavitary and intraorgan treatment. Simple performance of SMC therapy in combination with sodium salicylate solution microclysters and efficacy which was not inferior to intracavitary drug electrophoresis makes the method practicable in gynecology and physiotherapy.
Acute Disease↗
[New approaches to the diagnosis and treatment of inflammatory diseases of the adnexa uteri].
The paper summarizes follow-ups of 2500 patients with inflammatory diseases of the uterine appendages, provides evidence for the benefits of laparoscopic diagnosis and treatment of all types of this condition, which makes it possible to verify the diagnosis and perform less traumatic organ-sparing operations. To use combined antiinflammatory antibiotic therapy in view of the etiology of inflammation, as well as immunomodulators is the requisite condition for treating acute types of a disease. The new approaches to the diagnosis and treatment of inflammatory diseases of the uterine appendages substantially improved therapeutical outcomes and maintained female reproductive function.
Abdomen, Acute↗
[Errors in the diagnosis of tumors of the adnexa uteri and the means for their elimination].
Errors are described made in the course of diagnosis of "false" tumors of the uterine appendages of inflammatory genesis. An algorithm is developed of carrying out differential diagnosis between carcinoma of the ovary and "false" tumours of uterine appendages, involving ultrasonic investigation, computerized tomography and direct endolymphatic antibiotic therapy over a long period of time, which measures permitted a more accurate diagnosis to be made, an adequate surgical treatment to be instituted.
Adnexal Diseases↗
Immunological characteristics of women with inflammation of the adnexa uteri.
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Adult↗
[Experimental and clinical studies of ceftazidime in the field of obstetrics and gynecology].
Ceftazidime (CAZ) was studied for its transference into adnexa uteri and uterine tissues as well as for its effects and safety on gynecological infections. The results obtained are as follows: Peak levels of CAZ were obtained in the tissues of adnexa uteri and uteri at 15--30 minutes after one shot intravenous injection of CAZ 1 g, and relatively high concentrations were maintained for several hours. In the treatment of 33 cases of gynecological infections, the clinical efficacy of CAZ was assessed as excellent in 13 cases and effective in 20 cases. As for the bacteriological effects of CAZ, 95.5% of clinically isolated organisms were eradicated. The laboratory tests performed before and after administration of CAZ revealed rise in GOT, GPT values in 2 cases and eosinophilia in 1 case. However, these cases were all mild and required no particular measures.
Adolescent↗
[Fundamental and clinical studies on cefpimizole in the field of obstetrics and gynecology].
Cefpimizole (AC-1370) was studied for its transference into adnexa uteri and uterine tissues as well as for its effects and safety on gynecological infections. The results obtained are as follows: Peak levels of AC-1370 were obtained in the antecubital vein and uterine artery at 10 minutes, in the tissues of adnexa uteri and uteri about 30 minutes after one shot intravenous injection of AC-1370 1 g, and relatively high concentrations were maintained for several hours. In the treatment of 30 cases of gynecological infections, the clinical efficacy of AC-1370 was assessed as effective in all cases. As for the bacteriological effects of AC-1370, 77.6% of isolated organisms were eradicated and 90% of all cases were effective. Side effects and abnormal laboratory findings due to AC-1370 were not observed during and after administration.
Adult↗
[Pharmacokinetic and clinical studies on ceftriaxone in the field of obstetrics and gynecology].
Ceftriaxone (CTRX) was studied regarding its penetration into the adnexa uteri and uterine tissues, as well as its utility and safety in the treatment of patients with obstetric and gynecologic infections. The results obtained are summarized below. 1. When 1 g of CTRX was administered by intravenous bolus injection, Cmax in tissues of adnexa uteri and uterus ranged from 42.2 to 80.5 micrograms/g, Tmax ranged from 0.42 to 0.81 hour, and the AUC ranged from 314.9 to 606.9 micrograms.hr/g. Thus, drug penetration into these tissues was good. 2. Clinical efficacy of CTRX was evaluated in 29 obstetric and gynecological patients. The clinical efficacy was good in all cases. 3. Bacteriological effects of CTRX were very good, and 90% of the organisms isolated before treatment were eradicated. 4. Laboratory testing revealed an occurrence of mild eosinophilia in 1 case.
Abortion, Septic↗
[Pharmacokinetic and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Imipenem/cilastatin sodium (MK-0787/MK-0791) was studied for its penetration into the adnexa uteri and uterine tissue, as well as for its clinical efficacy in the treatment of patients with obstetric and gynecologic infections. The following results were obtained. When 500 mg/500 mg of MK-0787/MK-0791 was administered by an intravenous drip infusion, peak levels of MK-0787 in tissues of adnexa uteri and uterus ranged from 14.6 micrograms/g to 25.8 micrograms/g, Tmax ranged from 0.55 hour to 0.98 hour, and the AUC ranged from 25.6 micrograms X hr/g to 45.2 micrograms X hr/g. Thus, the penetration of the drug into these tissues was good. Clinical efficacy of MK-0787 was evaluated in 30 patients in the field of obstetrics and gynecology. The clinical efficacy was excellent or good in all patients. Bacteriological effects of MK-0787/MK-0791 were very good, and 90% of the organisms detected before the treatment were eradicated. The antimicrobial activity of MK-0787 was tested against pathogens isolated before, during and after the treatment. Mean MIC80 values of MK-0787 were 0.39-0.78 micrograms/ml against all Gram-positive bacteria, 0.20-0.39 micrograms/ml against all Gram-negative bacteria, and less than or equal to 0.10-0.20 micrograms/ml against all anaerobic bacteria. The antimicrobial activity of MK-0787 appeared very good. No side effects or abnormal laboratory findings were observed except a slight elevation of S-GPT in 1 patient.
Adult↗
[Transfer of cefuzonam into female genital organs].
Cefuzonam (CZON) was given intravenously at a 1 gram dose to 24 patients prior to abdominal total hysterectomy for uterine myoma. Concentrations of CZON in the serum of cubital vein, uterine artery, and in tissues of uterus and adnexa uteri were measured by the bioassay method. Bilateral uterine arteries were clamped at 15 and 30 minutes and 1, 2, 4 and 6 hours after the administrations of the drug. Measurements were done on 4 patients at each sampling. Concentrations of CZON in the serum of cubital vein and uterine artery changed in a similar manner with respective half-lives of 52.0 minutes and 48.2 minutes. Peak concentrations in oviduct, ovary, endometrium, myometrium, cervix uteri and portio vaginalis were reached at 15 minutes after drug administration. The peak concentration in the ovary was as high as 37.5 micrograms/g, and those in other tissues varied between 17.6 and 25.5 micrograms/g. Tissue concentrations decreased gradually after their peaks in similar manners to those in serum, and their half-lives ranged between 37.4 and 53.7 minutes. From these results, it was found that CZON was transferred to female genital organs in high enough concentrations to inhibit growth of bacteria which were often isolated from the pelvic inflammatory diseases, and CZON seemed to be highly effective to clinical pelvic inflammatory diseases.
Adnexa Uteri↗
Adnexal and cul-de-sac abnormalities: transvaginal sonography.
Sixty-seven patients selectively chosen from 354 undergoing conventional transabdominal (TA) sonography for evaluation of a clinically suspected adnexal mass subsequently underwent transvaginal (TV) sonography either because the TA sonograms were technically suboptimal or because it was not possible to characterize with certainty an abnormality identified with TA sonography. TV sonography added diagnostically useful information in 25 of 28 patients with cystic pathologic changes in the adnexa uteri. Eight of 12 patients with tuboovarian abscess and nonspecific adnexal masses visualized with TA sonography had tube-shaped fluid collections characteristic of pyosalpinx identified with TV sonography. TV sonography added diagnostically useful information in all seven patients with diseases of the cul-de-sac (rectouterine fossa) and allowed differentiation of adnexal from primary uterine disease in three patients with TA sonograms on which findings were equivocal. It also expedited the diagnosis of a tubal pregnancy in ten of 14 patients and was useful in the detection of adhesions and perforated intrauterine devices. These results indicate that adjunctive TV sonography can provide important diagnostic information.
Adnexal Diseases↗
Uterine metastases from breast cancer in a patient under tamoxifen therapy. Case report.
The authors report a case of metastases of breast cancer confined to the uterus and cervical subserous leiomyoma in a postmenopausal woman under tamoxifen therapy for two years. After abnormal uterine bleeding, pathologic examination on biopsy of a cervical polyp revealed cervical involvement secondary to lobular breast cancer. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Pathologic examination of the surgical specimen revealed both invasion of breast origin and of the cervix until the isthmus, endometrium and cervical subserous leiomyoma. The adnexa uteri were not affected. The possibility of uterine metastases in patients suffering from breast cancer, either undergoing tamoxifen therapy or not, always has to be considered.
Antineoplastic Agents, Hormonal↗
[The characteristics of the clinical manifestations and diagnostic criteria of progressive tubal pregnancy].
An analysis was performed of clinical manifestations and chief diagnostic criteria of progressive tubal pregnancy to allow some judgement about their informative value. The findings secured show the presence of bloody discharges, gnawing pain in the lower area of the abdomen, nausea, vomiting to be of most informative value. In vaginal examination, the following findings can be regarded as main diagnostic criteria: the presence of tumour-like formation in the projection of the adnexa uteri, softening of the uterus sizes. The best supplementary investigatory methods capable of providing relevant information included determination of beta-HG by laboratory means, laparoscopic diagnosis and transvaginal ultrasonography.
Disease Progression↗
[Clinical criteria of the risk of oncological diseases in women as a basis for prevention of reproductive system diseases].
A multifactorial analysis was done of clinical past history of 520 female patients with cancer of the ovary, 482 patients with cancer of the endometrium, and of 513 essentially healthy women (control group). 23 historical and clinical sings were regarded as risk factors for development of cancer of the ovary and endometrium (disordered menstrual and reproductive functions, chronic inflammatory processes, benign tumours of the uterus and adnexa uteri, pretumour affections of the skin, and other pathologies). Of these, 15 sings were recognized as being of high informative value.
Adolescent↗
[A rare case of ovarian cancer in a patient treated for secondary sterility].
The authors described a rare case of ovarian cancer in a young woman who looked for gynecological help because of secondary sterility. There were found cysts of the both ovaries, which were conservative treated by insistence of the patient for three months. After unsuccessful gestagenic therapy there was performed a gynecological laparoscopy, which showed that on one of the ovaries there was an exophyte growths suspected for carcinoma tissue. It was offered an emergency operation, which was made only after 1,5 months because of personal causes of the patient. It was taken a sample that was with unconvincing data for ovarian cancer. The clinical experience and professionalism of the surgical team were put on the test. It was performed a radical operation with removal of the uterus, adnexa uteri, partial peritoneoectomy, total lymph dissection, appendectomy, total omentectomy. The patient was discharged from hospital in good condition and she is liable to postoperative chemotherapy.
Adult↗
[Clinical effect of cefuzonam and its distribution into tissues in the field of obstetrics and gynecology].
The distribution of the new cephem antibiotic, cefuzonam (CZON) into adnexa uteri and uterine tissues, and clinical efficacy on patients with obstetric and gynecologic infections were studied. The results obtained are summarized as follows. 1. Concentrations of CZON in arterial and venous blood, oviduct, ovary, endometrium, myometrium, cervix uteri and portio vaginalis tissues were measured. The results demonstrated good transfer of the drug into various internal genital organs. 2. In clinical studies, CZON was given to 5 cases with various infections such as pyometra, acute vulvitis, pelvic peritonitis, pyelonephritis and puerperal intrauterine infection. Clinical efficacies were evaluated as excellent in 2 cases, and good in 3 cases. The efficacy rate was 100%. No side effects were observed in any cases. In laboratory tests, transient elevations of GOT, GPT and gamma-GTP were observed in 1 case. Therefore, it is concluded that CZON is a useful drug for various types of infections in the field of obstetrics and gynecology.
Adult↗