Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Science”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,423 records · Page 79Linked to original sources

The science of youth violence prevention. Progressing from developmental epidemiology to efficacy to effectiveness to public policy.

Public policy in the United States has historically considered youth violence as a moral problem to be punished after the fact, but growing scientific evidence supports a public health perspective on violent behavior as an interaction between cultural forces and failures in development. Prevention science has provided a bridge between an understanding of how chronic violence develops and how prevention programs can interrupt that development. Articles in this journal supplement provide yet another bridge between efficacious university-based programs and effective community-based programs. It is suggested that yet one more bridge will need to be constructed in future research between community-based programs that are known to be effective and community-wide implementation of prevention efforts at full scale. This last bridge integrates the science of children's development, the science of prevention, and the science of public policy.

Child↗

A bibliometric study on chemical information and computer sciences focusing on literature of JCICS.

A bibliometric approach was used to survey the state-of-the-art of research in the field of chemical information and computer sciences (CICS). By examining the CA database for the articles abstracted under the subsection "Chemical information, documentation, and data processing", Journal of Chemical Information and Computer Sciences (JCICS) was identified to have been the top journal in this subsection for the last 30 years. Based on this result, CA subsections and controlled index terms given to JCICS articles were analyzed to see trends in subjects and topics in the CICS field during the last two decades. These analyses revealed that the subjects of research in CICS have diversified from traditional information science and computer applications to chemistry to "molecular information sciences". The SCISEARCH database was used to grasp interdependency between JCICS and other key journals and also the international nature of JCICS in its publications and citedness.

Bibliometrics↗

Pharmaceutical sciences' manpower supply and internal rate of return.

A pharmacy student has many career options upon graduation. These options include graduate education in one of the pharmaceutical sciences and a retail pharmacy position. The attractive salaries offered by chain pharmacies play an important role in the recent graduate's career decision-making process. The purpose of this study is to provide a comparative assessment of the internal rate of return (IRR) for different pharmaceutical science career options as related to chain-store pharmacist earnings. Additionally, this study analyzes the effect of the IRR on the applicant pool size and composition for graduate study in pharmaceutical sciences. Income/age profiles were developed using public domain income data derived from salary surveys sponsored by professional associations. Based on these income/age profiles, IRRs were estimated for the pharmaceutical science disciplines, clinical pharmacy, pharmaceutics, medicinal chemistry, and pharmacy administration, and further differentiated for industry versus academic careers. The IRRs are the highest for Pharm.D.'s in academic careers (16.0%), followed by pharmaceutical scientists employed by pharmaceutical industry (8.13%). The IRR of pharmaceutical scientists in academia is lower than the return of other financial investment vehicles. Other authors have established a relationship between the IRR of a profession and a rise or decline in the applicant pool. The IRRs calculated here imply that this association can also be observed for the pharmaceutical scientist applicant pool. Low IRRs should result in a declining applicant pool. However, the last decade has shown an increase of 66% in the number of Ph.D.'s granted, while the percentage of Ph.D.'s granted to nonpharmacists or non-Americans has not increased significantly over the same time period.(ABSTRACT TRUNCATED AT 250 WORDS)

Career Choice↗

Paul Meehl as methodologist-philosopher of science: the formulation of metascience.

Paul Meehl's contributions to methodology and the philosophy of science extend well beyond his widely known writings in such areas as construct validity and statistical significance testing. I describe one of Meehl's less well-known, but potentially most important, methodological undertakings: his work on metascience, or the science of science. Metascience could ultimately revolutionize our conceptualizations and understanding of science and provide considerable help to practicing scientists and scientific endeavors, including efforts to advance the development and appraisal of theories in psychology.

Famous Persons↗

A lived experience of dualism between the natural and human science paradigms in nursing.

AIM: To describe the use of narrative as both phenomenon and method to illuminate college nurse educators' nursing knowledge development through their day-to-day stories on the institutional landscape, which shape and are shaped by health-care and nursing education changes. BACKGROUND: The Ontario health-care reform in Canada and a shift in nursing curriculum have brought to light a different dimension of a theory-practice issue. The traditional predominant natural science approach in nursing is now no longer considered responsive to the unique characteristics of patients' health-care needs. Emerging from current nursing education is an emphasis on a human science paradigm. However, as many college nurse educators moved back and forth between their classrooms to clinical settings, they experienced tremendous tensions in living between the new caring paradigm and the old culture of biomedical science ideology. Compounding this challenge is a lack of understanding by the policymakers and administrators of the importance of nurses' contribution vis-à-vis an ailing health-care system. This growing complexity demands that nursing, as a practice discipline, should articulate its unique body of knowledge for advancing contributions in health care. METHODS: My stories of experience and those of my participants were analysed narratively to determine the knowledge and understanding developed from living the complex and interwoven changes in nursing education and practice. FINDINGS: Through living, telling, retelling and reliving our stories, my participants and I recognized a false dualism between the seemingly polarized biomedical and human science paradigms. CONCLUSION: The meaning of certainty-uncertainty inherent in nursing teaching and practice demands that nurse educators rethink how stories of experience play out in their understanding of teaching future graduates the interrelationships between these two approaches.

Attitude of Health Personnel↗

Clinical science research.

Clinical science research incorporates the fields of clinical investigation and health services research. With a focus on the use of either human specimens or subjects, clinical investigation research projects translate knowledge gained from basic science research based on animal models for disease. The goal of clinical investigation is to develop new prevention, intervention, and therapeutic approaches to improve patient clinical outcomes. In contrast, health services research focuses on the improvement of the efficacy, cost-effectiveness, and outcomes of care. Health services research projects examine options to improve the health care delivery system, organization, financing, and reimbursement mechanisms in place today. The purpose of this article is to review common terminology and methodologic approaches that are used in clinical science research. The process of designing a research project is reviewed. Beginning with the development of a research question and hypothesis, the steps for successful completion of the project are discussed. Different study design approaches are presented with their respective strengths and weaknesses. The challenges associated with conducting a clinical research study are discussed, including the development of an appropriate sampling strategy, the designing of data collection, instruments, and the assurance of study data integrity. Possible threats to study validity and generalizability are assessed.One the major advantages of clinical research is that it offers an opportunity to study clinical questions in the clinical setting without the expenses of a basic research laboratory and basic science technology. Thus important clinical questions related to patient care, new technology assessment, clinical practice management, health care administration, or health policy may be addressed.

Health Services Research↗

Developing a science of land change: challenges and methodological issues.

Land-change science has emerged as a foundational element of global environment change and sustainability science. It seeks to understand the human and environment dynamics that give rise to changed land uses and covers, not only in terms of their type and magnitude but their location as well. This focus requires the integration of social, natural, and geographical information sciences. Each of these broad research communities has developed different ways to enter the land-change problem, each with different means of treating the locational specificity of the critical variables, such as linking the land manager to the parcel being managed. The resulting integration encounters various data, methodological, and analytical problems, especially those concerning aggregation and inference, land-use pixel links, data and measurement, and remote sensing analysis. Here, these integration problems, which hinder comprehensive understanding and theory development, are addressed. Their recognition and resolution are required for the sustained development of land-change science.

Journal Article↗

The rise and fall of dietetics and of nutrition science, 4000 BCE-2000 CE.

OBJECTIVE: To outline the history of dietetics since its beginnings in recorded history, and of nutrition science in its first phase beginning in the mid-nineteenth century and then its second phase in the second half of the twentieth century. METHOD: Three narrative overviews: of dietetics from its beginnings until after the end of the medieval and then Renaissance periods in Europe; of nutrition science in its first phase from its beginnings in the mid-nineteenth century until the middle of the twentieth century, with reasons for its rise; and of nutrition science in its second phase in the second half of the twentieth century, with reasons for its decline. CONCLUSIONS: In its third phase in the twenty-first century, the new nutrition science should regain much of the vision and scope of its preceding disciplines.

Dietetics↗

Science and sports: a brief history of muscle, motion and ad hoc organizations.

Both the history of biolocomotion (later to become motion analysis/biomechanics) and of electrology (later kinesiological electromyography) are to be traced back to approximatively the same period in the second half of the seventeenth century. The major contributors to these emergent sciences were Swammerdam in 1658 and Borelli in 1680. Some 150 years later, electrophysiological methods were derived and motion-cinephotography was developed from their pioneering work. Subsequently, use was made of motion analysis by means of cinephotography, forming a basis for biomechanics. The work of Marey in 1873 in particular stimulated the multidisciplinary study of human activity, providing models for contemporary sports scientists working in applied settings. The link between theory and practice in motion sciences and the multidisciplinary model of Marey were the motive and the example for establishing the Working Group of Biomechanics in the 1960s. This body has gone through a series of progressive developments, culminating in the approval of the World Commission of Science and Sports as a service group of the International Council for Sport Science and Physical Education (recognized by UNESCO).

Biomechanical Phenomena↗

Future directions for performance-related sports science research: an interdisciplinary approach.

The present paper is based on a review which was commissioned by the Sports Council (London) on behalf of the Open Section of the British Association of Sports Sciences (BASS). This was one of four such reviews which were collectively designed to provide information pertinent to the formulation of a strategy that would guide fundamental sports science research in the UK until the year 2000. All of the reviews were expected to focus on research that was relevant to the performance of the elite athlete and the specific brief of the Open Section Review was to concentrate on interdisciplinary research. The current paper established the unique value of interdisciplinary sports science research. Four themes were considered in some detail in order to review the extant interdisciplinary research and propose directions for future research involving an interdisciplinary approach. The four topics were talent identification, adherence, injuries and peaking. A critical review of each area revealed a lack of interdisciplinary research and recommendations for future research priorities were made. The paper is concluded with a brief outline of a strategy that would facilitate the development and expansion of interdisciplinary sports science research.

Athletic Injuries↗

Situating gender: Marie E. Zakrzewska and the place of science in women's medical education.

Marie E. Zakrzewska (1829-1902) is known among historians of women and medicine for her advocacy of the natural sciences at a time when most women physicians preferred to emphasize their nurturing qualities. This article suggests that Zakrzewska's views have been poorly understood because scholars have tried to position them along a fault line that divides femininity and sympathy from masculinity and science. It suggests instead that feminist scholarship on the "situatedness of gender" offers a more promising conceptual framework for understanding the diverse strategies women (and men) have utilized in trying to achieve their goals. Zakrzewska, unlike many of her colleagues, did not seek to empower feminine virtues as a way of justifying women's entry into the medical profession. Instead, she tried to reappropriate science for women and to use it as a weapon against the barriers designed to keep women out of the public sphere. She was fighting her own battle against the gendering of science.

Education, Medical↗

The fire ant wars. Nature and science in the pesticide controversies of the late twentieth century.

This essay uses an approach borrowed from environmental history to investigate the interaction of science and nature in a late twentieth-century controversy. This debate, over the proper response to fire ants that had been imported into the American South accidentally and then spread across the region, pitted Rachel Carson and loosely federated groups of conservationists, scientists, and citizens against the U.S. Department of Agriculture. The analysis falls into three sections: an examination of the natural history of the ants; an examination of the views of the competing factions; and an examination of how those views, transformed into action, affected the natural world. Both sides saw the ants in terms of a constellation of beliefs about the relationship between nature, science, and democracy. As various ideas were put into play, they interacted with the natural history of the insects in unexpected ways--and with consequences for the cultural authority of the antagonists. Combining insights from the history of science and environmental history helps explain how scientists gain and lose cultural authority and, more fundamentally, allows for an examination of how nature can be integrated into the history of science.

Animals↗

Why medicine cannot be a science.

My thesis is that, although medicine is scientific, it is not and can not become a science. After rejecting as flawed an argument attempting to show that medicine is already is science. I argue that a comparison of such basic, defining features as internal aims, criteria of success, and principles regulating the enterprises demonstrate that medicine and science are inherently different. I then argue that while it may be possible to reduce the cognitive content of medicine to biology, medicine itself cannot be reduced, for as an enterprise it possesses features that make it an inappropriate subject of reduction. I conclude by indicating four results that emerge from recognizing that medicine and science are basically distinct.

Medicine↗

Advances in American forensic sciences. California's role.

The forensic sciences in the United States, specifically forensic medicine, have benefited primarily from the advances made by the New York Medical Examiner Office pioneers and the philosophy developed in the Massachusetts medicolegal structure as begun in 1877. California's pioneering role is directly related to the development of criminalistics which in turn served as a stimulus for the improvement and development of forensic medicine in that state. Historically many private practitioners were involved in general criminalistics in California before the system of state criminalistic laboratories and criminal investigations was well established. Any report on the growth of the forensic sciences must include mention of the earlier pioneers including Heinrich, Kirk, Kytka, Crossman, Abernethy, Pinker, Helsel, and Noxley. A review of the current state of the art in the forensic sciences is presented, as is a review of the contributions of California to the development of American forensic sciences.

California↗

Physics for physicians: integrating science into the medical curriculum, 1910-1950.

One of the most difficult problems in twentieth-century medical education has been finding ways to successfully integrate the basic and applied sciences into the medical curriculum. Not only have medical students regarded basic sciences such as physics and biochemistry with distaste, but these subjects traditionally have been taught by pure scientists with little interest in the needs of medical students. In this paper, the author reviews the history of physics teaching at the Queen's University Faculty of Medicine in Canada, placing particular emphasis on the work of J.K. Robertson (1885-1958), professor of physics. Although physics no longer has the relevance to general medical training that it once had a study of Robertson's ideas and methods provides insight into the process of integrating basic science into medical training. Robertson's success in the endeavor was based largely on two factors his "sympathetic understanding" of the needs of medical students and his innovative combination of basic and applied science in one course--factors that are as important to medical teaching today as they were 50 years ago.

Canada↗

A pilot study of faculty development for basic science teachers.

PURPOSE: Relatively little research has focused on faculty development methods that assist basic science teachers to improve their instructional skills. This study was designed to assess the effectiveness for basic science faculty of a faculty development seminar series that had been previously shown useful for clinical teachers. METHOD: The Stanford Faculty Development Program's seminars on clinical teaching were adapted for basic science instruction. Eight pathology faculty participated in a series of nine small-group seminars designed to provide teachers with knowledge of a framework for analyzing teaching and identifying areas for improvement, and skill-based training in specific teaching behaviors. Each seminar included (1) brief lectures, (2) review of videotaped reenactments of teaching interactions, (3) role-play exercises with videotape review, and (4) formulation of personal and departmental teaching goals. RESULTS: Program evaluation included multiple measures: participant self-assessment, student ratings of the participants, and blinded ratings of pre- and post-seminar videotapes of participants' classroom teaching. All measures indicated a positive effect of the intervention. CONCLUSION: Faculty development programs have significant potential to enhance basic science instructors' teaching effectiveness.

Adult↗

The impact of centers and institutes on faculty life: findings from a study of basic science and internal medicine faculty at research-intensive medical schools.

PURPOSE: To examine the impact of organized research centers on faculty productivity and work life for basic science and internal medicine faculty at research-intensive medical schools. METHOD: In 2005, the authors administered a questionnaire to a random stratified sample of full-time faculty in basic science and internal medicine departments at the top 40 research-intensive U.S. medical schools. The survey instrument asked faculty about the extent of their involvement in centers and institutes, the direction and extent of their activities, and their satisfaction with various dimensions of work. RESULTS: A total of 778 faculty members completed the questionnaire (72.0%). Basic science faculty with center affiliations produced more research publications and grants while devoting comparable effort to teaching as their non-center-affiliated peers. These faculty reported greater dissatisfaction in workload and in the mix of their activities. Internal medicine MD center-affiliated faculty were more productive in research activities and spent less effort in patient care and more effort in research than their non-center-affiliated peers. These faculty were more satisfied with promotion, opportunities for research, and the pace of their professional advancement. CONCLUSIONS: Findings indicate that faculty from different departments and with different ranks and backgrounds interact with centers and institutes in multiple ways. For basic science faculty, center involvement appears to be an addition to, not a substitute for, their usual departmental obligations. For internal medicine MD faculty, center involvement appears to serve as an opportunity for protected effort in research away from the demands of clinical practice.

Biomedical Research↗

The value of basic science in clinical diagnosis.

BACKGROUND: The role of basic science knowledge in clinical diagnosis is unclear. There has been no experimental demonstration of its value in helping students recall and organize clinical information. This study examines how causal knowledge may lead to better recall and diagnostic skill over time. METHOD: Undergraduate medical students learned either four neurological or rheumatic disorders. One group learned a basic science explanation for the symptoms. The other learned epidemiological information. Both were then tested with the same set of clinical cases immediately after learning and one week later. RESULTS: On immediate test, there was no difference in accuracy (70% for both groups). However, one week later, performance in the epidemiology group dropped to 51%; the basic science group only dropped to 62%. CONCLUSIONS: Basic science knowledge relating causal knowledge to disease symptoms can improve diagnostic accuracy after a delay.

Education, Medical, Undergraduate↗