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Evaluation of the North Carolina Risk Reduction Program for smoking and alcohol.

Seventh grade students in two school systems in rural North Carolina were subjects for a program designed to reduce health risks associated with use/abuse of tobacco and alcohol. One school system was located in the central area of the state, and the other in the western mountains. Both groups were assessed before and after introduction of novel teaching programs dealing with alcohol and tobacco. Knowledge about smoking and alcohol increased in both sites (p less than .05). Attitudes toward alcohol did not change. Attitudes toward smoking eroded in both sites, with attitudes at one site showing a severe erosion (p less than .05). Smoking education in these communities may have conflicted strongly with ambient attitudes toward smoking, eliciting a "boomerang" effect.

Adolescent↗

Computer programs and datasheets. Initiative on quality control of the German Working-Group on Pediatric Diabetology.

Despite modern treatment regimens, late complications in IDDM patients are still prevalent. Even in developed countries, a significant number of patients do not get the treatment which would be considered optimal based on the present state of medical knowledge. Quality documentation provides a successful approach to unmask deficits and to improve the outcome of care. Structural aspects as well as process and outcome indicators are different in pediatric diabetology compared to the care of adult patients. The German Working Group on Pediatric Diabetology has discussed and finalized a Statement on Quality Control, including specific parameters to be recorded prospectively in all patients. Under the auspices of the German Ministry of Health, a Computer Program designed for inpatient and outpatient care in pediatric diabetology was developed. Among many other features, internal and external quality control according to the guidelines of the German Working Group are facilitated by this approach, as no separate data entry is required. This program is now widely used among pediatric--as well as some adult--diabetes centers in Germany. Regular external comparisons of quality indicators are organized by the Working Group.

Adolescent↗

Allergy prevention. Interventions during pregnancy and early infancy.

The increase in allergic disease in western, industrialized countries has been phenomenal. Although the reasons for this increase are unknown, it is clear that the primary management of allergies is prevention. There is now significant epidemiologic data suggesting that a program designed and focused on prevention will have a significant impact on the development of allergies. These include not only environmental, but also dietary restrictions. There remain, however, several major problems. Firstly, it is not clear which subjects will respond best to a program focusing on either pre-or postnatal prevention. Secondly, the immunological mechanisms involved remain unclear. For example, it would be highly desirable to have a readout that monitors the improvement in allergen avoidance, other than clinical response. This review will focus on the immunological background of allergy prevention, including epidemiologic observations and thoughts for future potential allergy prevention.

Female↗

[Teaching program for elderly women who care for elderly relatives in their home: report of experience].

This is a report of experience about the development of a program designed especially for the orientation of elderly people who care for elderly relatives at home. It was carried out by the coordinators of the Group of Attention for Elderly People's Health (GRASI), of the Campinas State University's Clinics Hospital. This program was developed based on the needs reported by elderly caregivers who take part in the activities of the GRASI. The participants reported that the program made coping with the difficulties related to caregiving better; that there had been an improvement in the understanding of the changes brought by the aging process; and that it made possible the development of procedures that make easier the daily relationship with the elderly that is being cared for.

Aged↗

Risk management in an IPA setting--Part I.

Over the past several years, HMO enrollment has grown the most in independent practice association (IPA) and network models. HMOs in general have expanded as a means to control the cost of health care. Key customers, including large employers and government agencies such as the Health Care Financing Administration (HCFA), require such control. IPA and network models retain a greater sense of choice on the part of participating physicians and patients than do closed-panel group- or staff-model programs. As physician and patient choice increases, however, the HMO's control over health care diminishes. Thus, customers require HMOs to manage health care. The HMO must market, develop delivery systems, meet regulatory requirements, and make profits. It must control both the quality and the cost of health care. Doing so without the level of control found in staff-model HMOs has created unique challenges for IPA HMO managers. IPA-model HMOs adapt quality improvement programs to this lesser level of control. Staff-model HMOs and hospitals closely link quality assurance to risk management. Programs designed to improve quality will naturally also reduce the risk of providing care below standards. This relationship is less clear in IPA- and network-model HMOs, in which the HMO does not provide the care. Thus, IPA-model quality improvement programs often do not address their risk management implications. This two-part article examines the differences between staff-model and IPA-model HMOs in liability and in ability to manage risk. In the first part, the nature of the risks is described. In the next issue of the journal, the management of those risks will be discussed.

Health Maintenance Organizations↗

[Subacromial impingement syndrome in athletes: prevention and exercise programs].

The shoulder joint, the most mobile joint in the human body, is at greater risks for injuries. Several factors contribute to shoulder impingement syndrome including rotator cuff weakness, capsular tightness, poor scapulohumeral rhythm, and muscle imbalance of the scapular upward rotation force couple. Rehabilitation and training of the shoulder in throwing and overhead athletes has dramatically improved during the last decade. There are numerous reasons for rapid return to athletic training and competition. A preventive program designed for the glenohumeral joint is mainly based on an appropriate preparation, which should include overall body conditioning, flexibility, and strengthening of the musculature around the glenohumeral joint and the scapula. Activity levels represent a helpful guide in determining an appropriate rehabilitation program for shoulder patients ranging from disabled to those competing at the highest levels of athletics. This article discusses issues related to prophylactic measures, non-operative treatment, postoperative treatment, and rehabilitation programme of impingement syndrome in athletes.

Athletic Injuries↗

Feasibility and outcome of tandem stem cell autotransplants in multiple myeloma.

BACKGROUND AND OBJECTIVES: Clinical trials have shown that high dose chemotherapy (HDT) with peripheral stem cell autotransplantation is presently the best treatment for patients with symptomatic multiple myeloma (MM). In the context of an outcomes research project, we analyzed the feasibility of this strategy in clinical practice in a large cohort of consecutive, unselected patients with newly diagnosed MM and looked at the major determinants of response of patients enrolled in a HDT with tandem autotransplantation (Total Therapy I, TTI) program. DESIGN AND METHODS: Two hundred and fourteen patients were treated outside of a clinical trial and regularly followed-up at our Center for symptomatic MM. Ninety-seven patients (45%) received conventional chemo-radiotherapy regimens, 110 (51%) entered the TTI program and the remaining 7 patients (3.3%) were enrolled in other programs involving HDT with autotransplantation. RESULTS: Patients enrolled in HDT with tandem autotransplantation programs were 14 years younger and less likely to have co-morbidities than patients treated with conventional therapy. Median overall survivals of the two groups were 60 and 33 months, respectively. Thirteen percent of the patients enrolled in the TTI program did not receive the first HDT with autotransplantation, mostly because of disease progression, and another 16% did not proceed to the second HDT with autotransplantation mainly because of infections or drug-related complications. Most patients achieved complete remission after the second autotransplantation, with acceptable toxicity. However, only patients with a major reduction of the myeloma burden at the end of induction therapy enjoyed significantly prolonged event-free and overall survivals. INTERPRETATION AND CONCLUSIONS: Approximately one third of patients with newly diagnosed symptomatic MM completed the TTI program. These data suggest the need to improve the induction therapy in order to increase both the number of patients able to proceed to autotransplantation programs and to enhance the rate of early response.

Adult↗

Adaptation to peripheral muscle training.

Ten healthy subjects underwent a 6-week dynamic exercise program designed to put a high relative load on individual muscle groups while maintaining low central circulatory stress levels. This was done to test the hypothesis that such "peripheral" training could produce skeletal muscle adaptation at low levels of myocardial work. Such a program may be useful in rehabilitating patients whose myocardial disease prevents adequate levels of participation in the traditional types of large muscle training. Strength testing, muscle biopsies and both submaximal and maximal bicycle ergometry were done to assess the effects of "peripheral" training. Heart rate during the training sessions decreased progressively over the 6 weeks (p less than 0.001). Quadriceps strength increased (p less than 0.02) with training as did both quadriceps (p less than 0.03) and gastrocnemius (p less than 0.008) fiber areas. Fiber composition was unchanged. Succinic dehydrogenase concentrations were unchanged while phosphorylase activity decreased in both muscle groups (p less than 0.03). Submaximum and maximum bicycle ergometry results were unchanged with training. The data show that dynamic training of small groups of muscles sequentially can produce significant skeletal muscle adaptation with little central circulatory stress. The effects of "peripheral" training in cardiac patients remain to be determined.

Adaptation, Physiological↗

Quality management by state Medicaid agencies converting to managed care: plans and current practice.

CONTEXT: Enrollment in Medicaid managed care plans has increased more than 5-fold in this decade, but how states monitor and encourage quality of care in these programs is not known. OBJECTIVE: To characterize the quality monitoring and assurance activities of state Medicaid agencies for Medicaid beneficiaries enrolled in comprehensive prepaid managed care programs. DESIGN: Structured telephone survey conducted between October 1996 and January 1997. SETTING: State Medicaid agencies. PARTICIPANTS: Representatives from all state Medicaid agencies, including the District of Columbia, with beneficiaries enrolled in comprehensive prepaid managed care plans as of July 1, 1996. MAIN OUTCOME MEASURES: Proportion of states with specific quality monitoring and assurance activities for Medicaid managed care. RESULTS: We surveyed all 34 states enrolling beneficiaries in comprehensive managed care programs. In 1996, all 34 states enrolled the population receiving assistance from the Aid to Families With Dependent Children (AFDC) program, while only 21 (62%) and 15 (44%) enrolled the disabled and elderly populations, respectively. In the period 1995 to 1996, 19 states (63%) collected data on satisfaction with care, and 25 states (83%) collected data on childhood immunizations. No more than half of the states collected data on other selected measures of access and quality, but a substantial number planned to collect such data in 1997. While at most 37% of states were providing comparative data to health plans, up to 80% were planning to provide such information in 1997. Similarly, while at most 10% of states provided beneficiaries with such information, up to 38% planned to do so in 1997. The breadth of contracting requirements designed to assure quality varied substantially across states. CONCLUSIONS: State Medicaid agencies have already begun adapting to their new roles as purchasers of health care. Continued monitoring is essential to ensure that state agencies implement planned programs and that quality of care for Medicaid enrollees is preserved or improved.

Health Care Surveys↗

Cardiac rehabilitation in patients with implantable defibrillators. Feasibility and complications.

OBJECTIVE: We examined patients with implantable cardioverter defibrillators (ICD) in order to demonstrate their safe participation in a standard rehabilitation program. DESIGN: Prospective cohort study of a consecutive series of patients after ICD implantation. Setting Inpatient rehabilitation center. PATIENTS AND METHODS: A total of 118 patients (73.7% male, mean age 60+/-11 years) took part for 23 +/- 4 days in a standard inpatient rehabilitation program including physical activity, psychological care, heart function seminars, and resuscitation exercises with family members. The following noninvasive tests were performed: symptomlimited exercise testing, two-dimensional echocardiography, Holter monitoring, telemetric ICD interrogation, optional fluoroscopy or X-ray examination of the thorax, and (in some patients) defibrillation threshold testing. RESULTS: Out of 118 patients 101 patients (85.6%) participated in regular ergometer training during which the initial workload of 23 +/- 11 Watts could be increased to 45 +/- 18 Watts. An individual conditioning program was assigned to 15% (n = 17) patients, thereby enabling the inclusion of all patients in the rehabilitation process. Under these conditions 12 patients (10%) experienced ICD malfunctions requiring therapy. As a consequence of all cardiac function tests, ICD reprogramming was necessary in 26 patients (22.1%). CONCLUSION: Following ICD implantation, patients may participate in a standard rehabilitation program without serious complications and with a significant increase in physical capacity. However, ICD malfunction occurs in approximately 10% of patients. Additional tests performed by skilled medical staff and appropriate technical equipment allows the ICD program to be optimized.

Aged↗

The recruitment of pathology residents: a 1987 conference report on challenges and responses.

There is general agreement within pathology that there is a serious problem in the recruitment of US medical graduates into the field. Basic to this decline is inadequate exposure of medical students to the pathologist as a physician who is important to the care of patients and open to a range of clinical and research opportunities unparalleled in other medical specialties. Programs designed to increase the familiarity of students with pathology, both within the curriculum and outside of it, beginning before medical school and extending after medical school, have been proposed to reverse the downtrend in recruitment. Changes in the basic structure of pathology training programs, which would shorten the time commitment, are also considered important in increasing the attractiveness of a pathology career.

Foreign Professional Personnel↗

Sudden death and the competitive athlete: perspectives on preparticipation screening studies.

Sudden death in healthy athletes is uncommon but, when it occurs, the primary mechanism is cardiovascular. The major cause of sudden death in the young athlete is hypertrophic cardiomyopathy or related conditions characterized by left ventricular hypertrophy, aortic rupture due to cystic medial necrosis and congenital coronary artery abnormalities. In the middle-aged or older athlete, coronary artery disease is the most significant cause of sudden death. Noninvasive screening procedures are currently available that can detect most subjects at risk of sudden death. However, although some potentially lethal diseases can be excluded by a relatively simple screening program, other diseases require expensive procedures, such as echocardiography and exercise electrocardiographic stress testing. This means that the sensitivity of detecting diseases leading to sudden death increases in proportion to the financial resources that can be applied to the screening program. Thus, when a screening program designed to identify all cardiac diseases that have the potential to cause sudden death is planned by a community, school or nonprofessional athletic team, the costs will almost undoubtedly be considered prohibitive. The practicality of applying a community- or school-initiated screening program can be questioned because of the very low incidence of sudden unexpected death in young healthy individuals. It is therefore likely that comprehensive screening programs will be confined to individuals or organizations with adequate financial resources. Less expensive, limited screening can be undertaken by individuals or groups to identify some subjects at risk of sudden death during athletic competition.

Adult↗

Intersect: identification and visualization of overlaps in database search results.

UNLABELLED: The determination of distant evolutionary relationships remains an important biological problem, and distant homologs often appear in statistically insignificant regions of sequence similarity searches. Intersect is a computer program designed to identify and visualize the overlaps between sets of sequences reported by multiple database searches. This capability extends the usefulness of database search results and aids researchers in identifying the individual sequences that best bridge sequence families and superfamilies. AVAILABILITY: The Intersect program is available from the Babbitt laboratory website at http://www.babbittlab.ucsf.edu/software/intersect

Algorithms↗

Implementing the COACH relationship model: health promotion for mothers and children.

Program designers and nurses developed and implemented the COACH Relationship Model to help low-income mothers change health-related behaviors as part of a clinical trial conducted from 1990 to 1994 of the impact of nurse home visitation. By first orienting the program nurses to the theoretical underpinnings (caring, ecological, role supplementation, and self-efficacy theories) and then involving them in developing program materials to translate the theoretical and philosophical concepts into nursing interventions, the essential features of the relationship model were retained through the implementation process.

Child↗

Antiulcer prescribing program in a state correctional system.

OBJECTIVE: To describe a formulary antiulcer agent prescribing program developed as the result of a drug use evaluation (DUE). Program implementation, methods, cost impact, and results of a follow-up DUE are provided. BACKGROUND: The institution is a 51,000-bed correctional system consisting of 40 separate units each containing an ambulatory care clinic. Medication orders are transmitted via mainframe computer system to one of four pharmacies, which collectively dispense an average of 4000 medication orders (30 days' supply) per day. METHODS: Results from the antiulcer agent (cimetidine, ranitidine, sucralfate) DUE revealed that the agents studied were prescribed in dosages and durations exceeding criteria developed by the Pharmacy and Therapeutics Committee. A program designed to reduce dosages to maintenance therapy after eight weeks at treatment dosage was developed by the Pharmacy and Therapeutics Committee with staff physician input. Antiulcer agent use and expenditures were followed and a follow-up DUE was completed seven months after program implementation. Antacid use and frequency of upper gastrointestinal studies that were ordered were followed. RESULTS: The follow-up DUE showed the mean daily dosage for prescribed histamine2-receptor antagonists decreased (cimetidine from 694 to 454 mg, ranitidine from 280 to 183 mg) and the mean duration of therapy decreased from 14 to 10 months. The percentage of patients with potentially significant drug interactions decreased from 14.2 to 6.5 percent. The mean number of antiulcer agents dosage units dispensed per month decreased by 24,461 units, resulting in a projected annual savings of $327,273. There were no identifiable clinically important changes in the use of antacid products or prescribing of upper gastrointestinal studies. CONCLUSIONS: A cost-savings program sponsored by the pharmacy and therapeutics committee decreased costs, corrected prescribing to more closely meet preset criteria, and produced no discernable unfavorable effect on patient care.

Adult↗

Results after two years of non-operative treatment of occlusal surface in children with high caries prevalence.

The aim of this study was to describe the 2-year results of an individualized treatment program designed to control occlusal caries in erupting first permanent molars. The sample consisted of 145 five-to-six-year-old students divided into a control group (n = 71) and a test group (n = 74). All test children received a biannual basic preventive program and a recall system according to individual disease activity. The basic program consisted of 3 (March) and 2 (August) sessions of oral hygiene orientation and toothbrushing with fluoride gel. The analysis of the baseline and 1-2-year data showed a significant reduction in the number of active lesions in the test group. In the control group, there were initially 70 active lesions and after two years 68 surfaces remained with disease and 24 surfaces had been filled. The children in the test group had 80 surfaces with active lesions initially and after two years only 3 surfaces with disease remained. From the 15 cavitated lesions, only 5 surfaces needed to be filled. This program showed that care of erupting teeth on an individualized basis can control occlusal caries.

Cariostatic Agents↗

Community organized food and nutrition education: participation, attitudes and nutritional risk in seniors.

UNLABELLED: Evergreen Action Nutrition (EAN) is a health promotion program designed to facilitate relatively healthy members of a seniors recreation center to maintain their nutritional health as they age. A main goal of this project was to demonstrate the feasibility and relevance of using the community organization approach to develop a nutrition education program for seniors. METHODS: Using the current membership list, seniors were randomly selected to receive a mailed baseline (n=247) questionnaire. A follow-up survey (n=251) was sent out to randomly selected members three years later to determine participation in EAN and reported behavior change. Although not the same individuals, responses were compared to baseline to determine changes in nutritional risk. Items from the Diet and Health Knowledge survey were compared by EAN participation. RESULTS: The program had a large reach with 162 survey respondents (64.5%) reporting some level of participation and 51% reporting "frequent" participation. Use of informal forms of education predominated (e.g. displays). Significant differences were found between baseline and follow-up for risk attributed to low intake of fruits and vegetables and frequency of eating, with EAN participants having reduced risk of low fruit and vegetable intake. Those participating in formal education (e.g. food workshops) reported more frequent changes in food practices than those participating in informal activities. EAN participants appear to have more healthy nutrition attitudes/beliefs. CONCLUSION: The community organization approach to program planning and delivery leads to the development of diverse and appropriate nutrition education activities for seniors. Informal and formal health promotion activities can be successfully implemented in recreation centers.

Aged↗

Health promotion strategies for prevention of human immunodeficiency virus infection among minority adolescents.

Programs designed to increase self-protective behaviors are urgently needed to avert a marked increase in HIV infection among minority adolescent populations. AIDS interventions which neglect any component of the prevention triad severely limit potential for positively impacting on adolescent risk behaviors. Proactive programs which integrate these equally critical components, on the other hand, have a greater likelihood of achieving maximal outreach and effectiveness, and consequently preventing the spread of HIV infection among minority adolescent populations.

Acquired Immunodeficiency Syndrome↗