Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Integrated Programs”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,423 records · Page 79Linked to original sources
PubMed1992

Adjunctive desipramine in the treatment of cocaine abusing schizophrenics.

Because schizophrenic patients have a lifetime prevalence rate for cocaine abuse between 15 and 50 percent, the use of adjunctive pharmacotherapy should be considered in cocaine-abuse treatment programs. This 12-week, open-label outpatient study compares 12 cocaine-abusing schizophrenic patients treated with desipramine (DMI) 100 to 150 mg and antipsychotic agents to 15 patients treated with only antipsychotic agents (no DMI). All 27 patients participated in a Dual Diagnosis Relapse Prevention (DDRP) program, which integrates traditional substance-abuse relapse prevention and psychiatric social skills training. The DMI group was more likely to complete the study (83% vs. 60%, odds ratio = 3.3, NS) and had fewer cocaine-positive urines during the last 6 weeks (20% vs. 50%, odds ratio = 4.0, p < .01). In the context of a specialized dual diagnosis treatment program, patients receiving DMI substantially decreased cocaine usage and had improved psychiatric symptoms.

Adult↗
PubMed1985

A computerised experimental file.

A commercially available program which integrates word processing, spreadsheet, data base, and graph facilities, is used on a microcomputer to write a proforma for an experimental file. The proforma file contains empty forms for all envisaged documentation collected during the experiment's duration. This includes an outline protocol, cost estimate, literature search, detailed protocol, data collection forms, project account, and final report. The program allows linking of spreadsheets, thus for instance enabling date and time information entered on the daily log of events to be automatically transferred to the labour cost form. Introduction of this concept has greatly reduced the amount of time spent on research documentation and the risk of data adulteration through repeated transcription. It has also improved control over research expenses and standardization of trial document formats.

Computers↗
PubMed1993

Integrating the twelve-step approach with traditional psychotherapy for the treatment of eating disorders.

The treatment outcome literature for anorexia nervosa and bulimia indicates that approximately two thirds of patients treated with brief to moderate length interventions have favorable responses. The remaining one third are more difficult to treat and appear to require longer term and more intensive intervention. These patients can usually be characterized as having more severe Axis I and Axis II comorbidity. This manuscript focuses on a longer term treatment program that integrates psychodynamically oriented psychotherapy with a 12-step component. Specific issues that are addressed include the theoretical dilemma between the two models, advantages and disadvantages of adding a 12-step component, and how various subgroups of patients respond to the model. The clinical viability and preliminary impressions regarding outcome with this model are also offered.

Anorexia Nervosa↗
PubMed1999

Reengineering outcomes management: an integrated approach to managing data, systems, and processes.

The integration of outcomes management into organizational reengineering projects is often overlooked or marginalized in proportion to the entire project. Incorporation of an integrated outcomes management program strengthens the overall quality of reengineering projects and enhances their sustainability. This article presents a case study in which data, systems, and processes were reengineered to form an effective Outcomes Management program as a component of the organization's overall project. The authors describe eight steps to develop and monitor an integrated outcomes management program. An example of an integrated report format is included.

Attitude of Health Personnel↗
PubMed2002

The effect of nutritional intervention program on the prevalence of anemia among pregnant women in rural areas of Belbis district-Sharkia Governorate-Egypt.

OBJECTIVE: to determine the prevalence of anemia among pregnant women in rural areas of Belbis district, Sharkia Governorate, Egypt, and to assess the effect of iron supplementation and nutritional educational program on the level of hemoglobin in blood. DESIGN: A cross-sectional study was conducted followed by intervention prospective study. SUBJECTS: Women attended the antenatal clinics in two primary health care units of Belbis district through December 2000, which amount to 100 women 50 in each primary health care unit. Data was collected as regard to their age, parity, educational level and occupation. All participating women were subjected to hemoglobin analysis during the first time, after one month and two months. Women with hemoglobin level less than 11 gm/dl were considered anemic. STATISTICAL ANALYSIS: Chi-square and "t" tests (paired and unpaired) were applied to test the relationships among study variables. RESULTS: The prevalence of anemia among pregnant women at the first time booking was 55%. After the intervention nutrition education program and iron supplementation the prevalence declined after three months down to 32%. While the prevalence after the same period for pregnant women in the control group (non intervention group) was 46%. Both parity and educational level affected significantly the prevalence of anemia only among the intervention group. This study suggests that anemia is still high among pregnant women and integrated intervention programs should be considered prior to conception.

Adult↗
PubMed1987

Inpatient treatment of complicated agoraphobia and panic disorder.

Despite recent advances in the treatment of agoraphobia and panic disorder, some patients do not respond to standard outpatient regimens of biological and psychosocial intervention and may require more intensive, closely supervised care. The authors describe a specialized inpatient program that integrates pharmacotherapy, intensive levels of exposure and other behavioral therapies, a structured and strategically reinforcing environment, panic and anxiety management strategies, and other interventions designed specifically for patients with complicated panic-based disorders. Outcome data for 25 patients indicate that after a mean stay of 35 days, 19 patients were significantly improved. These preliminary results suggest that appropriately designed inpatient programs offer an effective treatment option for some patients with refractory conditions of agoraphobia or panic disorder.

Adult↗
PubMed1997

Toward a virtual-labo-system for metabolic engineering: development of biochemical engineering system analyzing tool-kit (BEST-KIT).

BEST-KIT is an efficient and user-friendly "biochemical engineering system analyzing tool-kit" integrated the following key modules: 1) mathematical modeling and editing of reaction-scheme, 2) automatic derivation of differential equations, 3) numerical calculation, 4) nonlinear optimization, 5) visualization, 6) retrieve the information on reaction mechanism and kinetic parameters from data-base of metabolic pathways. The users of this simulator are assumed to be unfamiliar with computer technology and with computer programming. The integrated interface (UNIX version) is based on Xlib, XToolkit and OSF/Motif Widget.

Biochemistry↗
PubMed2005

Foxa2 integrates the transcriptional response of the hepatocyte to fasting.

Survival during prolonged food deprivation depends on the activation of hepatic gluconeogenesis. Inappropriate regulation of this process is a hallmark of diabetes and other metabolic diseases. Activation of the genes encoding gluconeogenic enzymes is mediated by hormone-responsive transcription factors such as the cyclic AMP response element binding protein (CREB) and the glucocorticoid receptor (GR). Here we show using cell-type-specific gene ablation that the winged helix transcription factor Foxa2 is required for activation of the hepatic gluconeogenic program during fasting. Specifically, Foxa2 promotes gene activation both by cyclic AMP, the second messenger for glucagon, and glucocorticoids. Foxa2 mediates these effects by enabling recruitment of CREB and GR to their respective target sites in chromatin. We conclude that Foxa2 is required for execution of the hepatic gluconeogenic program by integrating the transcriptional response of the hepatocyte to hormonal stimulation.

Animals↗
PubMed2004

A randomized controlled trial of integrated versus parallel housing services for homeless adults with severe mental illness.

This study compared two contemporary approaches to linking housing and mental health services. In the integrated housing program, case management and housing services were provided by teams within a single agency and were closely coordinated. In the parallel housing condition, case management services were provided by mobile assertive community treatment teams and housing by routine community-based landlords. Adults with severe mental illness who were at high risk for homelessness (n = 121; 72.7% schizophrenia spectrum) were assigned randomly to integrated or parallel housing services and followed for 18 months. Integrated housing services led to more days of stable housing and greater life satisfaction than parallel housing services, especially for male participants. Integrated housing services were also associated with greater reductions in psychiatric symptoms. Closer integration between clinical and housing services, and greater use of supervised living settings, led to more time in stable housing for participants in the integrated housing services condition and was associated with greater gains in several outcome domains.

Adult↗
PubMed1997

Impact of representative payees on substance use by homeless persons with serious mental illness.

OBJECTIVE: Assignment of representative payees, third parties responsible for managing clients' funds, has been proposed to counter potential use of public support payments for abused substances by people with severe mental illness and substance use disorders. This study examines substance use outcomes in a sample of homeless persons with serious mental illness and substance use disorders, some of whom were assigned representative payees. METHODS: The subjects were participating in the Access to Community Care and Effective Services and Supports (ACCESS) program, a federally funded demonstration program on integrating service systems. Clients were assessed at baseline and three months after case management services were initiated. Factorial repeated-measures analysis of covariance was used to examine substance use among four client subgroups, two of which had payees and two of which did not. RESULTS: Clients in this sample (N = 1,348) showed significant improvement on all measures of substance use over the first three months in the program. Those with payees showed no greater improvement in substance abuse than those without payees, although they did have fewer days of homelessness. CONCLUSIONS: This study failed to find evidence that merely adding external money management services to existing services improves substance abuse outcomes among clients who had dual diagnoses and were homeless. Besides assigning a payee, structured behavioral interventions may be needed to produce additional clinical benefits.

Adult↗
PubMed1988

Progress report.

Explore the source record for details and available documents.

Africa↗