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At least 1,405 records · Page 78Linked to original sources

An overview of experience with ketoconazole shampoo.

The spectrum of disease known as dandruff/seborrhoeic dermatitis has been shown to be due to infection of the skin by the Pityrosporon species of fungus. Ketoconazole shampoo has been shown to suppress effectively both the organism's growth and the symptoms and signs of the clinical disorder.

Clinical Trials as Topic↗

Proliferating trichilemmal cyst in an organoid nevus.

An unusual tumor mass of the scalp found in an elderly woman is presented. This lesion had many features simulating a verrucous squamous cell carcinoma of the scalp. Pathologic findings eventually revealed the tumor mass to be a proliferating trichilemmal cyst. Differentiation between a benign and malignant process in these lesions can sometimes be difficult. Clinical as well as histopathologic evaluation is necessary to make an accurate diagnosis.

Aged↗

[Repair of widely infected scalp defect and osteomyelitis with free radial forearm flap: a case report].

A 60-year-old female was admitted with large frontal scalp defect associated with osteomyelitis due to chronic infection. Debridement of the infected scalp and frontal bone and the transplantation of the free radial forearm flap with vascular anastomosis was carried out. The wound cured uneventfully. Cranioplasty was performed ten months after the first operation. Transplantation of free radial forearm flap was first reported in 1982 by Song in China and has proved to be a very effective operative method, especially for the repair of large infected wounds. This is because good blood supply results from the anastomosis of larger vessels, and its cleansing effects can eradicate infections and prompt rapid wound healing.

Female↗

Myiasis due to Cardylobia anthropophaga, the 'Tumbu fly' in a Sri Lankan infant.

A case of myiasis due to Cardylobia anthropophaga (Blanchard) (Diptera: Calliphoridae), the 'Tumbu fly', is reported for the first time in Sri Lanka, in a 10 month old infant. The infection was acquired in Zimbabwe. The child had appeared 'unwell' for nearly a week before the detection of the skin lesions. The main clinical features were irritability, restlessness and the appearance of three small lumps on the scalp behind the right ear. Identification of the fly larva and the management of myiasis are discussed.

Animals↗

[Permanent hair loss after Kerion Celsi].

Kerion celsi is a deep dermatophytic infection of the scalp. The diagnosis is based on the characteristic clinical picture and is verified by examination for the fungus. Treatment consists of griseofulvin in a dosage of 10 mg/kg/day. The present article is a retrospective investigation of 18 patients with kerion celsi who had been treated in the Department of Dermatology in Marselisborg Hospital during the period 1978-1989. Sixteen out of the 18 patients were children. Twelve of the children were boys. A questionnaire investigation revealed that only five out of 18 patients had normal hair growth. We found a connection between the degree of severity of the alopecia and the age of the patient and the extent of the primary affection, respectively, so that low patient age and large primary affection result in a poorer prognosis. On the other hand, we have not found any connection between the latent period from the first appearance of symptoms and relevant treatment and the alopecia. Nor is there any evidence that treatment with systemic steroid is of significance for the prognosis.

Adult↗

[Angiolymphoid hyperplasia with eosinophilia. Histologic study and successful therapy with the argon laser].

We report a case of angiolymphoid hyperplasia with eosinophilia (AHE) with regional lymphadenopathy. The multiple papules were composed of both a lymphoid infiltrate of predominant T-cell type with eosinophils and anomalous vascular proliferation lined by "histiocytoid" endothelial cells, which were in close association with a ruined artery at the subcutaneous level in the largest nodule. Immunoelectron microscopy revealed factor-VIII-related antigen to be concentrated within the Weibel-Palade bodies of the endothelial cells. Their cytoplasmic filaments consisted of vimentin. In the pericytes large amounts of actin were demonstrable. Since AHE has a benign progressive course and only local recurrence is noted, the lesions were treated with argon laser. Subsequently, lymphadenopathy resolved spontaneously and the blood parameters normalized. There is no evidence of recurrence 1 year after treatment.

Angiolymphoid Hyperplasia with Eosinophilia↗

[Angiolymphoid hyperplasia with eosinophils. Case report and differentiation from Kimura disease].

We report a 40-year-old patient, who presented with a nodular tumor at the scalp. The histological diagnosis was angiolymphoid hyperplasia with eosinophils (ALHE). Immunohistochemical staining of the proliferating vessels was characteristic for endothelial cells. The perivascular inflammatory infiltrate mainly consisted of CD4-positive lymphocytes. Recently it has become clear that Kimura disease, which was thought to be a variant of ALHE, can be distinguished from ALHE by clinical, histological and immunohistochemical criteria and constitutes its own clinical identity. While ALHE is a localized proliferation of endothelial cells, Kimura disease is a proliferation of lymphoid cells characterized by invasive growth and possibly lymphadenopathy.

Adult↗

Cranial fasciitis: case report.

A 2-year-old boy with cranial fasciitis is described. He had a rapidly growing subcutaneous right occipital mass, which was associated with a dimple in the overlying skin. It appeared similar to a malignant subcutaneous tumor with skin invasion. Total resection of the tumor was performed, and the histological diagnosis, cranial fasciitis, was confirmed.

Child, Preschool↗

[Diagnosis and therapy of diffuse hair loss].

Dependent on the nature and intensity of the causative damage, the clinical picture of diffuse loss of hair varies considerably. We give a review on 4 typical clinical forms with different courses and degrees of hair loss. The differentiation of these variants may help to estimate the possible causes and prognosis and avoid unnecessary investigations.

Alopecia↗

Cradle cap.

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Dermatitis, Seborrheic↗

Primary adenoid cystic carcinoma masquerading as syringoma of the scalp.

We report a case of primary adenoid cystic carcinoma of the scalp in a 72-year-old man. It consisted of syringomalike papules scattered on an erythematous plaque that showed a loss of hair. Histologically, the papular lesion at first showed numerous tadpole-like tubular structures similar to those found in syringoma. Subsequent histologic studies over 2 years revealed the presence of numerous cribriform tumor masses penetrating into the subcutis, reaching the galea aponeurotica. Immunohistochemically, the neoplastic cells showed no staining with either polyclonal (P) or monoclonal (M) antibodies to carcinoembryonic antigen. M-cytokeratin, M-vimentin, and P-S-100 protein antibodies were positive only focally as were other antibodies, including anti-actin, anti-human lactalbumin, anti-beta 2 microglobulin, and breast cancer--associated antigens. The neoplastic cells showed no binding to lectins that characteristically react with the sweat apparatus, except for concanavalin A (con A) and peanut agglutinin (PNA), although the striking histopathologic resemblance to syringoma suggested its histogenic relation to eccrine glands initially.

Adenoma↗