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At least 1,405 records · Page 78Linked to original sources
PubMed1987

Retinal vascular loss in idiopathic central serous chorioretinopathy with bullous retinal detachment.

Three patients with idiopathic central serous chorioretinopathy (ICSC) and bullous retinal detachment (RD) were examined at least 2 years after the onset of the disease in one patient and over 10 years in the other two patients. There were large areas of retinal pigment epithelium (RPE) degeneration in each patient. Interestingly, there was loss of retinal vascular trees in the inferior peripheral retina where the subretinal fluid presumably persisted for a long time. In one patient, there was a retinal neovascularization with sea-fan formation along the border of the vascular loss. To the authors' knowledge, this finding has not been described in the literature.

Adult↗
PubMed2004

Characteristics and surgical outcomes of paediatric retinal detachment.

PURPOSE: To report the clinical features and surgical and visual outcomes of rhegmatogenous retinal detachment (RRD) in the paediatric population. METHODS: A retrospective review of children (aged 0-15 years) who underwent primary surgical repair for RRD at the Hiroshima University Hospital between 1988 and 2001. RESULTS: In all 53 eyes of 49 patients were identified; paediatric RRD accounted for 3.1% of 1779 eyes with RRD operated on during this period. The causes of RRD included blunt trauma (27%), myopia (25%), idiopathic (20%), familial exudative vitreoretinopathy (13%), and others. Among 55 eyes, 12 (22%) already had proliferative vitreoretinopathy (PVR) of grade C or D preoperatively. The median initial visual acuity (VA) was 0.3. Retinal reattachment was achieved with a single operation in 78%. Final retinal reattachment was achieved in 87%. Retinal reattachment rates with and without PVR were 42% and 100%, respectively (P<0.01). Median final VA was 0.7. Final VA was > or =0.1 in 73% and > or =0.5 in 53%; four eyes had a final VA of no light perception. The presence of preoperative PVR (P=0.03) and the initial VA (P<0.0001) significantly affected final VA. CONCLUSIONS: Paediatric RRD is characterised by a delay in diagnosis, as evidenced by the high rate of PVR at presentation. Retinal reattachment was adversely affected by the presence of PVR. Final VA correlated with the initial VA and was significantly affected by preoperative PVR. Early diagnosis may improve the visual prognosis of paediatric retinal detachment.

Adolescent↗
PubMed1996

[Usefulness of color Doppler ultrasonography in diagnosis of retinal detachment].

PURPOSE: Possibility of visualising the vessels within retinal detachment. MATERIAL AND METHOD: Examinations were performed using "Color Doppler" and "Power Doppler" methods on 46 eyes with linear hyperechogenic lesions within vitreous body found in US B-mode examination. RESULTS: The results show the possibilities of Doppler examination in visualising branches of the central retinal artery within the detached retina. The presence of vessels in the membranous proliferations was not found. CONCLUSION: Color Doppler ultrasonography can be used in localising the position of retina, especially when proliferative lesions and detachment coexist.

Humans↗
PubMed2001

FGFR1, signaling, and AP-1 expression after retinal detachment: reactive Müller and RPE cells.

PURPOSE: To identify changes in cellular signaling pathways and AP-1 expression in retina and retinal pigmented epithelium (RPE) after experimental retinal detachment (RD). METHODS: Cat and rabbit neural retinas were separated from the RPE in vivo for 5 minutes to 28 days. Tissues were removed and processed for Western blotting, immunohistochemistry, in situ hybridization, and immunoprecipitation experiments. RESULTS: An ordered sequence of events occurs after RD: (1) fibroblast growth factor (FGF) receptor 1 (FGFR1, flg) is phosphorylated in the retina within 15 minutes and dephosphorylated 2 hours after RD; (2) The extracellular signal-regulated kinase (ERK) is phosphorylated in both Müller and RPE cells within 15 minutes and remains so for several days; (3) De novo expression of c-fos mRNA coincides with increased c-Fos and c-Jun immunoreactivity in both Müller and RPE cells; (4) CREB is phosphorylated in a subpopulation of photoreceptors; and (5) STAT3 and NF-kappaB are activated in inner nuclear layer cells by 1 day of RD. CONCLUSIONS: These data suggest that nonneuronal cells (RPE and Müller cells) respond to RD very rapidly by stimulating ERK signaling and AP-1 transcription factor expression. Furthermore, these data suggest that basic fibroblast growth factor (FGF-2, bFGF) is involved in initiating the retina's earliest responses to RD. The events described here precede changes in gene expression and morphology that can have serious effects on visual outcome in humans treated for retinal detachment or other retinal injuries.

Animals↗
PubMed1991

[Combined surgery for complicated retinal detachment].

During 1986-1989, the authors treated 23 cases of complicated retinal detachment with vitrectomy in combination with reattachment surgery and intraocular injection of C3F8 gas. The PVR gradings were C1, 3 cases; C2, 7 cases; C3, 8 cases; D1, 4 cases; and D2, 1 case. Retinal breaks occurred in 16 cases, in whom the rate of surgical success was 65.2%. The visual acuity improved in 66.6% of the cases after operation. The advantages, the actual procedures and the causes of failure of the combined surgery were discussed.

Adolescent↗
PubMed2006

Outcomes of surgery for progressive symptomatic retinal detachment complicating retinoschisis.

PURPOSE: To select the best surgical technique and predict the surgical success in cases of progressive symptomatic retinal detachment complicating retinoschisis (PSRDCR). METHODS: Cases were divided into three groups: group I, those with outer layer breaks (OLBs) positioned anterior to the equator and no proliferative vitreoretinopathy (PVR); group II, those with OLB(s) at or posterior to the equator and no PVR at presentation; and group III, PVR greater than grade B at presentation. A retrospective study of 30 such eyes presenting to the authors and a review of the 47 previously reported cases to which the three-group anatomical classification might be applied were performed. RESULTS: In group I, the overall primary and final success rates were 85% (17/20) and 95% (19/20), respectively. In group II, the corresponding data were 67% (34/51) and 94% (48/51), respectively. Group III eyes fared badly with primary and final success rates of 0 (0/6) and 17% (1/6), respectively. CONCLUSION: The overall 66% primary anatomical success rate was lower than those reported in most series of rhegmatogenous retinal detachment uncomplicated by retinoschisis. In group I, the surgical technique used had no detectable influence on outcome. Vitrectomy appears to have been the procedure of choice in group II, but a significant P value could not be demonstrated to support it (Yates corrected chi test, P = 0.84). This study, however, had very low power with which to investigate for such effects. PVR greater than grade B at presentation was not previously been recognized in cases of PSRDCR and when present was associated with very poor primary and final reattachment rates.

Adult↗
PubMed1977

[The indications for the preventive treatment of retinal detachment (author's transl)].

The author describes the genuine indications for the preventive treatment of retinal detachment. He was above all guided by the minute observations of the eye fundus of two eyes with the Goldmann-glass. The author's long experience and his auto-observation of the retinal detachment operation and of preventive treatment show the confidence which can be given to the ideas published in this article.

Fundus Oculi↗
PubMed1975

[Peripheral retinal circulation times in connection with retinal detachment (author's transl)].

Concerning the pathogenesis of retinal detachment 4 groups of each 10 eyes have been examined by fluorescein angiography: the periphery of normal eyes (Table 2), ophthalmoscopically inconspicuous sectors of patients with detachment (Table 3), the area of lattice degeneration, radial perivascular degeneration and round holes without detachment (Table 4) and the area of tears and holes, when detachment has taken place (Table 5). The time passing between the injection of dye into the cubital vein and the first arterial filling in the retinal periphery is practically equal in all groups. The prolongation of retinal circulation time II from the first arterial to the complete venous filling in areas of lattice degeneration etc. without detachment seems to be in connection with small vessel closures. The striking short retinal circulation time I from the first arterial to the first venous filling in the cases of detachment is apparently caused by capillary dilatations central of the tears and holes; the dilated capillaries seem to have the function of a arteriovenous anastomosis. Own measurements of circulation times in the area of optic disc (Table 1), performed for comparisments, are accordant to literature.

Adolescent↗
PubMed1995

[Retinal detachment and laser drainage].

OBJECTIVE: To compare laser and 30G needle perforation of the choroid for drainage of subretinal fluid. METHOD: Hundred and six cases of retinal detachment were operated on by episcleral buckle, retinopexy and external drainage of subretinal fluid. After radial sclerotomy, the choroid was perforated in 53 cases with Argon laser (group I) and in 53 other cases with 30G needle (group II). Complications were compared between both groups. RESULTS: Group I (laser drainage): In one of 53 eyes (1.8%), a retinal perforation occurred. In this eye, the retinal detachment was shallow. In an other eye (1.8%), retinal perforation occurred secondary to incarceration of the retina at the drainage site. Two eyes (3.6%) had limited hemorrhage at the drainage site. Group II (30G needle drainage): Three of 53 eyes (3.6%) had direct retinal perforation, and three (3.6%) had perforation secondary to retinal incarceration at the drainage site. Seven eyes (13.2%) had subretinal hemorrhage. CONCLUSION: Laser is safer than 30G needle for perforation of the choroid and drainage of subretinal fluid, and is associated with a lower incidence of retinal perforations and subretinal hemorrhages.

Adolescent↗
PubMed1977

[Factors influencing the urgency of repair of retinal detachment (author's transl)].

An earlier publication (1974) described the urgency for surgical repair of some retinal detachments. The presurgical state of the macula provides a basis for categorizing detachments into 5 prognostic groups. Due to different degrees of macular detachment a statistical significance was present in the postsurgical visual acuity. The following clinical findings define the urgency for repair of a retinal detachment: 1. the macula attached but threatened by an approaching bullous, 2. the macula partially detached, 3. the macula detached for 1 day but less than 1 week, and 4. the macula detached in an old or highly myopic patient.

Adult↗
PubMed1982

[Outcome of the unaffected eye in retinal detachment. Study of 1148 patients].

We have found a global bilateral retinal detachments (R.D.) rate of 15,52% over a population of 1148 patients. 60% of these bilateral R.D. have been seen by us for the first time at the moment of the detachment of the second eye. The actual percentage of R.D. on a second eye that was free of any R.D. at the first examination is 3,5% only, and it climbs to 4,45% if we consider only the second eyes harboring dangerous peripheral retinal lesions. This result compares favourably to the 10% to 20% second eye R.D. rate in the absence of preventive treatment; it has been obtained through a systematic prophylaxy of all retinal breaks and almost all lattice, snowflake, and schisis by cryoapplication or xenon photocoagulation or mostly argon laser photocoagulation. In the absence of any peripheral retinal lesion systematic equatorial argon laser circular photocoagulations can be useful.

Cryosurgery↗
PubMed1992

Retinal detachment after refractive surgery for myopia.

Refractive surgery has been used widely in some countries for the last 20 years for the correction of myopia. Radial keratotomy and keratomileusis, the most common procedures, may concur with retinal detachment. A total of 14 eyes in 12 patients, 7 after keratomileusis and 7 after radial keratotomy, which had either asymptomatic or symptomatic retinal breaks, subclinical and clinical rhegmatogenous retinal detachments, or both, are discussed here. Five eyes were treated with either laser photocoagulation or cryopexy alone, seven eyes with a scleral buckling procedure, one eye with vitrectomy, and one eye was not operated on. At the final follow-up examination, anatomic reattachment had been achieved in 12 of 14 eyes (85.7%). Visual acuity improved in 3 eyes (21.4%), remained stable in 9 eyes (64.3%), and was worse in 2 eyes (14.3%). The scleral buckling procedures used in the repair of retinal detachment induced refractive changes by modifying axial length and corneal curvature, with recurrence of myopia and astigmatism. Myopia increased a mean of -3.00 diopters in 6 of 7 eyes (86%). Myopic astigmatism power changed a mean of -1.00 diopter in 5 eyes (71%), and the astigmatic axes shifted in 3 eyes (43%). This situation could be prevented with an early peripheral search for and treatment of peripheral retinal degenerative pathologic changes, by avoiding encircling bucklings, or by using alternative methods of treatment.

Adult↗
PubMed1977

360-degree buckling as the procedure of choice in cases of retinal detachment with poor prognosis.

A 360-degree scleral buckling procedure was used 82 cases of retinal detachment with poor prognosis. This procedure was successful in 58.6% of the cases after one operation and 76.8% after two operations. Because the complications observed were partially attributed to the extensiveness of the operation, it is proposed that this procedure be reserved for certain cases of retinal detachment with poor prognosis.

Anterior Chamber↗
PubMed2000

Long-term visual recovery after scleral buckling procedure of rhegmatogenous retinal detachment involving the macula.

The long-term visual recovery after a scleral buckling procedure for rhegmatogenous retinal detachment involving the macula was investigated retrospectively. The patients had been treated with a segmental or encircling scleral buckle procedure and in this study the follow-up period was between 5 and 11 years. In order to investigate the natural course of functional recovery of the reattached retina, all cases with a history of intraocular surgery or trauma were excluded. In this investigation, 34 patients were selected in which 35 eyes were studied. The best corrected visual acuities between a 6-month and 5-year postoperative period were compared. They were found to be more improved 5 years after surgery than after 6-month by two or more lines in 19 eyes (54%). In these 19 eyes, the visual acuities continued to improve up to 10 years after surgery. Improvement in the long-term postoperative visual acuity was found to correlate with the shorter duration of macular detachment (30 days), zero or mild myopia (-6 diopters) and to a lesser extent, retinal detachment. the visual function of the reattached human retinas may continue to improve over the long term, especially when these beneficial factors are present.

Adult↗
PubMed1979

[Intolerance causes of indentation material in retinal detachment surgery (author's transl)].

129 Lincoff sponge's rejection, representing 4,3% of our retinal detachment surgeries during 4 years have been studied. Men were twice more than women, the larger the amount of material was placed the more frequent rejections appeared. Most rejections (56,2%) occured during the first 4 months. Percentage of infection was roughly not influenced by the time after retinal detachment surgery.

Adolescent↗
PubMed1986

Retinal detachment in patients with proliferative sickle cell retinopathy.

Results and complications of surgical treatment for retinal detachment in thirteen patients with proliferative sickle cell retinopathy are reported. Eleven had maintained or improved visual acuity after treatment. Methods and complications of exchange transfusion in eight patients are described. The pathogenesis and methods of treatment of these retinal detachments and the benefits of exchange transfusion are discussed.

Adolescent↗
PubMed1988

Retinal detachment due to firecracker injury.

Seven cases of retinal detachment due to firecracker injury are reported. Most involved young boys. Associated anterior segment changes as well as the nature of the retinal breaks attested to the similarity between firecracker injuries and blunt contusion injuries. Despite successful retinal reattachment in all cases, visual results were poor. To prevent visual loss from firecracker injury, educational programs directed to school age boys seem needed.

Adolescent↗
PubMed1995

Systemic lupus erythematosus with choroidopathy and serous retinal detachment.

Systemic lupus erythematosus associated ocular manifestations usually consist of cotton-wool spots and retinal hemorrhages. The authors report one case of lupus choroidopathy revealed by bilateral serous retinal detachment, occurring 4 months after a systemic flare-up of the disease. An immune complexes-mediated phenomenon is involved in these manifestations, which are usually controlled by systemic corticosteroids and immunosuppressive agents. Plasma exchanges were successfully applied in this case, resulting in a disappearance of the retinal detachment in one month.

Adult↗