Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Pulpitis”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,405 records · Page 78Linked to original sources

[Acute and chronic toothache].

Toothache occurs as a result of pulpal and periodontal diseases. Due to the nature of their innervation pain is the only means for both pulp and dentine to react to all kinds of external stimuli. The actual mechanism of sensory transmission, however, has not been clarified, yet. In contrast to this, the innervation of the periodontium offers a wide range of mechano-sensitive receptors. Chronic dental pain is mainly the result of inflammatory reactions. Nerve sprouting, summation, convergence in the trigeminal system and regional inflammatory conditions modulate the local pain process, thus complicating diagnosis. The differential diagnostic clarification with regard to neuralgiform and ENT-diseases therefore requires special care with case history and status. Although there have been advances in pain research over the last few years, no fundamental development in dental diagnosis has been brought about, yet. Probing, sensitivity- and percussion testing as well as x-ray exposure are still the most important diagnostic tools for the dental practitioner.

Acute Disease↗

[Quantitative evaluation of the immunoglobulin G, A and M in the human dental pulp].

The presence of immunoglobulins G, A and M was studied in human dental pulps using a quantitative method of radial immunodiffusion. Valid data on the amounts of IgG, IgA and IgM were obtained on the basis of measured concentrations of immunoglobulins in each pulp sample and their correlation with total protein concentrations. The results indicated IgG to be present in 100%, IgA in 15% and IgM in 8% of 13 pulp samples affected by chronic inflammation. The mean values of IgG, IgA and IgM thus determined were 84.3, 4.4 and 1.4 mg/g protein, respectively. In intact pulp tissue, however, no presence of immunoglobulins G, A and M could be detected using the same method as above. The results obtained suggested the possibility of local synthesis of immunoglobulins in chronically inflamed pulp tissue, indicated that nonspecific inflammatory reaction may have occurred concurrently with some specific immunologic reactions. The predominance of IgG pointed to immunologic reactions of early types II and III hypersensitivity.

Dental Pulp↗

[Randomized study of amoxicillin-clavulanic acid versus amoxicillin-metronidazole combinations in pyogenic infections of dental origin].

Thirty patients, without any valve defect, cardiac malformation or previous antibiotic administration and presenting dental infections, have been treated either with amoxycillin-clavulanic acid or amoxycillin and metronidazole. Aerobic and anaerobic bacteria have been isolated. These infections were due to mixed flora. Nearly one half of anaerobes were Peptostreptococcus, S. milleri and S. sanguis being predominant among aerobes. The species identified were those found in the mouth in the absence of infection becoming as opportunistic flora. The percentage of cures was equivalent in the two groups. the association amoxycillin-clavulanic acid seems to be as active as amoxycillin + metronidazole on the microflora isolated from dentogenous pyogenic infections.

Adolescent↗

[The effect of caries and pulp inflammation on the mineral component of dentin].

A total of 94 dentin biopsy specimens of normal teeth, of those with caries and inflammations of the pulp were examined by phase x-ray diffraction analysis. The findings evidence changed ratio and concentrations of chemical elements and complexes (apatite phases) in the mineral component structure. Crystallographic studies have revealed a less symmetric crystal lattice and its deformation directly related to the pathologic process intensity.

Adult↗

Restorative and endodontic management of an anomalous mandibular molar.

Morphologic variations of dental hard tissue should be recognized and considered during restorative procedures. Overlooking anomalies increases the potential for clinical complications. Amalgam was used erroneously in a patient when the presence of a paramolar structure was overlooked. The clinical complications that resulted from overlooking the anomaly led to restorative, endodontic, and periodontal failures. The present report describes the use of conservative endodontics and a cast restoration, taking into account the presence of the paramolar structure, to correct the case.

Adult↗

[Pulpal effects of etching in the use of direct attachments].

Recurring enamel etching was observed to value the effects on pulp response. Four teeth were extracted and analysed by O.M.; no cellular alterations were observed except a slight inflammatory alteration testified by congested vessels and presence of fibroblasts.

Acid Etching, Dental↗

Pulpal studies: biocompatibility or effectiveness of marginal seal?

Standards presently used to evaluate the biologic compatibility of dental restorative materials are examined and their inherent shortcomings are noted in this report. Studies citing the alleged effects of dental materials on the pulp are reviewed and compared to new theories, which suggest that the principal cause of pulpal inflammation is bacterial infiltration. Thus, studies that are not able to exclude bacteria as a variable cannot be used to draw conclusions as to the cause of inflammatory changes. This paper presents a proposal to alter the current biocompatibility testing methods to methods that can distinguish between the effects of materials and the effects of bacteria on the pulp.

Biocompatible Materials↗

Lymphatic vessels in inflamed human dental pulp.

Investigation has been performed on both the light and electron microscopic characteristics of the lymphatic vessels present in the dental pulp of human teeth which have been affected by serious carious lesions. These conditions provoke a severe inflammatory response resulting in structural and functional modifications of the tissue; increase of the tissue pressure is followed by the need for a more intensive lymphatic drainage. In the inflamed pulps, dilated lymphatic vessels with distended walls and "open junctions" between endothelial cells are detectable. On the other hand they lack certain endothelial structures which characterize the morphology of these vessels under normal conditions. In the pulpal regions affected by fibrotic proliferation shrunken vessels with irregular profiles are present. From these observations it is possible to obtain other information on the mechanisms regulating the lymphatic drainage in different structural and functional conditions of the interstitium.

Dental Pulp↗

[Relationship between grade I and II inflammatory foci and certain inflammatory ophthalmic diseases].

The purpose of the study was demonstration of relations between grade I and II inflammatory foci in the oral cavity and certain inflammatory diseases of the eyes. Forty-three patients of either sex were studied. They were aged 19 to 78 years and were referred with the diagnosis of optic neuritis (intraocular and retrobulbar), iritis, retinitis and keratitis. Apart from routine clinical and radiological investigations the electrocutaneous test, the test for pulp viability with faradic current, and Schüller's iodine test were done. In 31 patients the electrocutaneous test was positive.

Adult↗

Marginal bacterial leakage and pulp reactions in Class II composite resin restorations in vivo.

The presence of stainable bacteria under restorations and pulp reactions in 36 teeth restored in vivo with a modified Class II composite resin restoration with two different dentine treatment techniques were studied on three separate follow-up occasions (1-3, 7-10 and 28-32 days). Half of the cavities showed stainable bacteria at the cavity margins and bottoms. Teeth restored with method A (Gluma/Occlusin) showed significantly fewer restorations with stainable bacteria then teeth restored with method B (Life/Occlusin) (p less than 0.05). Significantly more restorations with detectable bacteria were found after 28-32 days and restorative method B (p less than 0.05). There were no differences in occurrence and grade of pulp inflammation for the different dentine treatment techniques and time periods.

Acid Etching, Dental↗

Inhibition of lipoxygenase of rat dental pulp and human platelets by phenolic dental medicaments.

The effects of phenolic dental medicaments on lipoxygenase activities of rat dental pulp and human platelets were studied. The major product derived from [14C] arachidonic acid by the homogenate of rat dental pulp was 12-HETE (15-HETE). Eugenol and p-chlorophenol dose-dependently inhibited HETEs formation. The IC50 values of eugenol and p-chlorophenol were 0.62 and 0.34 mM respectively. The concentrations of these compounds that inhibit lipoxygenase were similar to those required to inhibit cyclooxygenase. These compounds also inhibited 12-lipoxygenase of human platelets with a similar range of concentrations. The results show that phenolic dental medicaments inhibit pulpal and platelet lipoxygenase. Thus, inhibition of arachidonic acid metabolism by phenolic dental medicaments via the lipoxygenase pathway may be involved in the analgesic and anti-inflammatory effects of the medicaments in endodontic therapy.

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid↗

An alternative hypothesis to the cause of pulpal inflammation in teeth treated with phosphoric acid on the dentin.

This paper explores the possibility that the inflammatory response in pulpal tissues noted in some early studies when dentin was treated with phosphoric acid was not caused by the acid. It suggests that the inflammatory response was caused by the prolonged exposure to zinc oxide-eugenol and documents many reports that show ZOE to be a relatively toxic material. The paper also suggests that biocompatibility studies as performed today may be inappropriate.

Acid Etching, Dental↗