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[Histogenesis of skeletogenic tissue in bone regeneration during distraction].

Light and electron microscopy were employed to study the histogenesis of the skeletogenous tissue during stable distraction osteosynthesis according to G. A. Ilizarov. Osteosynthesis proceeded on the basis of the invariably existing fibrillar connective tissue growth plate situated in the medium part of the distraction regenerate. Osteogenesis was continuously accompanied by angiogenesis. Preservation of the connective tissue plate is accounted for by the stimulating influence of distraction on fibrillogenesis. The authors suggest the common character of the histogenesis of the vascular and bone tissues in the connective tissue blastema of the interfragmental distraction regenerate.

Animals↗

[Mandibular distraction].

The authors review the bone lengthening techniques used in orthopaedics, analyse the application of osteogenesis by surgical distraction of the mandible and describe the progress in techniques and equipment. The presentation of clinical cases of mandibular hypoplasia treated by intraoral distraction emphasizes the value of this new technique, particularly in terms of the morphological results, which are superior to those obtained by conventional techniques.

Child↗

Transpalatal distraction as a method of maxillary expansion.

Conventional devices used for surgically assisted rapid palatal expansion are tooth-borne. Dental fixation entails a number of possible drawbacks such as loss of anchorage, skeletal relapse during and after the expansion period, cortical fenestration and buccal root resorption. A bone-borne titanium device with interchangeable expansion modules, used with a callous distraction policy, is presented.

Anesthesia, General↗

Ligamentotaxis in pseudarthrosis of the scaphoid bone (preliminary report).

Three cases are reported of pseudarthrosis of the scaphoid bone which have been treated by distraction with an external fixator employing ligamentotaxis. The investigations of Ilizarov and collaborators are discussed, pertaining as they do to stimulation of osteogenesis by distraction. Also considered are the possible indications for use of the method in some unfavourable fresh fractures of the scaphoid.

Adult↗

Endoscopic mandibular osteotomy, and placement and activation of a semiburied distractor.

PURPOSE: The purpose of this study was to demonstrate the feasibility of endoscopic placement and activation of a semiburied distraction device in the porcine mandible. MATERIALS AND METHODS: Sixteen cadaver and two live anesthetized minipigs were used in this study. Access to the mandible was gained through two 1.0-cm submandibular incisions used for a working port and a visualization port. Under endoscopic visualization, dissection was carried sharply to the mandible and completed in the subperiosteal plane. Landmarks were identified through the endoscope, and a mandibular angle osteotomy was created. A semiburied distractor was then implanted, fixed to the mandible, and activated to create a bone gap. Finally, the site was explored through a submandibular incision to verify the accuracy of the endoscopic procedure. RESULTS: Endoscopic exposure; accurate identification of landmarks; creation of an osteotomy; and placement, fixation, and activation of a semiburied distractor were achieved in all 18 specimens. The inferior alveolar nerve was identified as the bone gap was expanded. CONCLUSION: The results of this study indicate that the endoscopic approach described here allows exposure and osteotomy of the mandible, and placement, fixation, and activation of a distractor. In the future, this technique will be used with totally buried, miniature distraction devices.

Animals↗

Possibility of "distraction arthrogenesis": first report in rabbit model.

We investigated the possibility of articular cartilage distraction for use in reconstructing joint structure and for increasing the donor site of osteochondral grafts. Intraarticular osteotomy was performed at the femoral condyle in 12 Japanese white rabbits. The bone segment was fixed with a specially designed external fixator. After a 3-week waiting period, distraction was performed intermittently for 3 weeks (0.7 mm x 3 times per week) in the distraction group (n = 7) and, in the remaining animals (gap group; n = 5), a gap of 6.3 mm in length was made at surgery. All rabbits received etidronate injections (20 mg/kg x2 times per week) for 5 weeks, to slow mineralization. The femoral condyle was harvested 9 weeks postoperatively and decalcified sagittal sections were stained and evaluated, using a histological grading scale. In the distraction group, distraction of 4.2 +/- 1.4 mm was achieved, and the distracted cartilage area was filled with regenerated cartilage, without any gap between the regenerated and the adjacent articular cartilage. This regenerated cartilage showed metachromasia with toluidine blue. In the gap group, newly formed cartilage tissue was folded from the edge of the osteotomy site and fibrous tissue was interposed in the gap. The histological grading score was significantly lower in the distraction group (P < 0.02). Our preliminary results demonstrated the possibility of cartilage distraction; however, long-term observation will be necessary to confirm the characteristics of the distracted cartilage. We may call the process "distraction arthrogenesis", because the entire articular entity, which consists of cartilage, subchondral bone, and bone, could be distracted at once.

Animals↗