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PubMed2001

Chinese writing function in patients with left versus right putaminal hemorrhage.

This study was designed to explore the Chinese writing function of patients with subcortical stroke. Two cohorts of patient subjects with either the left or the right subcortical strokes, mainly putaminal hemorrhagic strokes, and one group of normal controls participated in the study. All participants received a writing test battery including the three aspects of writing function, that is, Spontaneous Writing, Writing to Dictation, and Writing from Copy, as well as a battery of non-writing linguistic tests. Comparing with normal controls revealed that writing function change occurred in both patient groups. The deficits in the patients with the left subcortical stroke essentially included Spontaneous Writing, and Writing to Dictation. These impairments were most likely secondary to aphasic disorders. The writing problem, mainly Writing from Copy, was noted in the patients with the right subcortical stroke. This deficit, however, was independent of the core linguistic impairment. On the basis of the results, we suggest that the lesion involving white matter in the left hemisphere probably interrupts left perisylvian cortical language organization in a manner that produces problems with spontaneous writing and writing to dictation, which are language-related, associated with lesion in the dominant hemisphere. This further suggests that left or right subcortical lesions in the putamen and surrounding white matter are associated with differential effects (language vs. non-language based effects) which are similar to such differences observed with left vs. right cortical lesions.

Adult↗
PubMed2003

Progressive anomia with preserved oral spelling and automatic speech.

We report a patient, Newton, with a progressive classical anomia resulting from focal degeneration of the left hemisphere. In naming tasks Newton spelt aloud picture names that he could not retrieve, indicating a dissociation between orthography and phonology. Unusually, his writing and letter-pointing performance were impaired and spelling was achieved only through alphabet recitation. A study of automatic speech tasks demonstrated strikingly preserved naming performance on automatic compared to nominative tasks. We argue that automatic tasks provide phonological cues that facilitate phonological activation. With progression of disease Newton has shown increasing difficulty reading and repeating words, which we interpret in terms of a progressive elevation in the threshold for activation of phonology. Phonological cueing of picture names has yielded superior naming than word reading and even repetition, a finding consistent with the notion that task characteristics influence likelihood of phonological activation and naming success, but contrary to the notion that there exist separate task-specific output systems. We conclude that Newton exhibits a unique pattern of deficits, which have theoretical relevance for the debate on the relationship between phonology and orthography, the role of automatic speech and the relationship between naming, reading and repetition.

Aged↗
PubMed2006

Dysexecutive agraphia: a major executive dysfunction sign.

Different types of writing disorders associated with brain pathology have been described. Limited mention the writing disturbances associated with prefrontal pathology, however, is found. Clinical observations of patients not only with focal prefrontal pathology but also with other conditions affecting the frontal system (e.g., traumatic head injury, dementia) confirm the assumption that these patients present an overt decrease in the ability to express ideas in writing. It is proposed that complex aspects of writing, such as planning, narrative coherence, and maintained attention, are significantly disturbed in cases of impairments of executive functions. Frontal lobe patients not only have difficulties in keeping the effort required for writing, but also to organize the ideas in the written texts. The term dysexecutive agraphia is proposed to refer to this writing disorder. Three illustrative cases are presented. It is finally suggested that questions regarding the ability to write should be included in dementia questionnaires and executive functioning testing.

Adult↗
PubMed1979

Sex differences and the incidence of left-handedness.

The higher incidence of left-handedness among males still remains a manifest and interesting phenomenon. For instance, Clark indicated that 7.84% of her male respondents were left-handed compared to 3.91% of the females. A study in South Africa among 882 students (mean age 13 years) yielded similar results: 11.13% of the males were left-handed compared to 7.69% of the females.

Adolescent↗
PubMed1965

Mirror writing.

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Classification↗
PubMed1981

Children's, adolescents', and adults' reports of hand preference: homogeneity and discriminating power of selected tasks.

A factor analysis, measures of internal consistency, and item analyses were conducted on the self-reported hand preference for the 15 activities recommended by Raczkowski, Kalat, and Nebes (1974) as reliable and valid indices of hand preference. Data from 1952 subjects, ranging in age from 8 to 70 years, were analyzed in toto as well as by age and sex. The factor analysis revealed the presence of only a single dimension. The internal consistency was uniformly high for all age and sex cohorts (a greater than or equal to .91). The item analyses showed that, in the aggregate, preference for hammering, drawing, and writing were the activities most strongly correlated with hand dominance determined on the basis of an unweighted composite of all the tasks. However, at ages 9 and 10, the hand used for hammering was not as strong an indicator of overall hand preference as writing and drawing. In contrast, with adult subjects (19 years and older), writing and drawing were slightly less satisfactory measures of overall manual preference, while use of hammer retained its high predictive value.

Adolescent↗
PubMed2003

Agraphia with abnormal writing stroke sequences due to cerebral infarction.

A 65-year-old, right-handed man presented with speech and gait disturbances. He was alert and cooperative, showing mild right hemiparesis and sensory disturbance. Spontaneous speech was fluent; object naming, word fluency and reading were fully preserved. Sentence repetition and verbal comprehension were mildly impaired. Writing was slow, hesitant and difficult for both spontaneous writing and dictation. Copying was better, although he had some difficulty in copying letters and also complex figures. Sequences of strokes in forming written characters were abnormal; strokes were formed by piecing together several fragments. Computed tomography and magnetic resonance imaging showed a subcortical infarct in the left frontoparietal region. Characteristics of agraphia resembled 'apractic agraphia' and agraphia may have resulted largely from loss or unavailability of the memory of motor patterns necessary for writing letters.

Aged↗
PubMed1993

Spared written naming of proper nouns: a case report.

In this study we describe an investigation into the residual written word retrieval skills of M.E.D., a patient with a severe aphasia. M.E.D.'s performance on written naming and writing to dictation tasks showed a distinctive pattern of performance across semantic categories. The patient's ability to write the names of countries and famous people was consistently superior to her ability to write the names of objects. These results could be considered as indicative of a double dissociation in the proper nouns category, as there are already patients on record who have a selective deficit in retrieving proper nouns.

Anomia↗