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A probabilistic approach to the analysis of the frequency of diploid formation in yeast (Saccharomyces cerevisiae) mating.

Conditions of optimizing mating efficiency in the yeast. Saccharomyces cerevisiae were tested and measured as a number of prototrophic diploids. It was found that the process of diploid formation could be controlled by suitably adjusting cell densities in liquid mating medium and alpha: a mating type cell ratio. When the first was about 5 x 10(8) per ml and the second 1:10, respectively, every alpha cell was able to find a partner of opposite mating type. Some mathematical models of the "courtship" in yeast were advanced and the conclusions are discussed in the light of recent data on mating pathway in S. cerevisiae.

Crosses, Genetic↗

Reproductive isolation between Florida strains of Aedes aegypti and Aedes albopictus.

The dynamics of heterospecific and conspecific mating between Florida strains of Aedes aegypti and Aedes albopictus was examined. In nonchoice experiments where conspecific males were not available, dissection of the spermathecae showed that heterospecific insemination was an infrequent event for both species combinations (10.6% for Ae. albopictus with Ae. aegypti males, 3.6% for the reciprocal cross). Few eggs were produced from heterospecific crosses and all were nonviable. Frequency of heterospecific mating was not increased when the hindtarsi of females were removed, eliminating a significant mechanism for fending off unwanted courtship. When held with males of both species, females mated with conspecifics and oviposited without regard to the presence of heterospecifics. In low density experiments, a single female of either species caged with an excess of heterospecific males, the conspecific male always located and inseminated the female. These results indicate that significant prezygotic and postzygotic reproductive isolation exists between Ae. aegypti and Ae. albopictus.

Aedes↗

[Relapsing parotiditis: its etiopathology and treatment].

In this paper 85 cases of relapsing Parotiditis are presented, with the aim to ascertain the degree of accuracy provided by treatments with vitamin B complex, anti-inflammatory drugs or catchers of free radicals. Perusal of the bibliography and proposal of considering the malady divided in two stages. The first one would be characterized for metabolic alterations of the saccharoid cycle with scarce yielding of energy (ATP). Therefore failure of the Na/L bomb, which phenomenon is linked to an enzymatic protein deficiency and/or coenzyme of the B complex vitamins, being this condition provoked for a dietetic deficiencies, intestinal malabsorption due to alcoholic oedema, excessive expenditure of energy among drug-addicts, anemia, diabetes, etc. From this moment on appears the second stage--the inflammatory--with the whole metabolic and biochemical courtship of structural and functional irreversible damages.

Anti-Inflammatory Agents↗

Student responses to economic reform in China.

This paper describes survey research suggesting diverse trends in the behavior and attitudes of Chinese students which often conflict with Chinese tradition and customs as well as with official Chinese government ideology. The decline of personal sacrifice for the social cause and the decline of self discipline are examined. Also addressed is what seems to be a rapid change in courtship and sexual attitudes among Chinese students, which has developed during the past decade. Finally, the varied causes of these changes, most of which are directly or indirectly related to China's economic reform program, are discussed.

Adolescent↗

Direct development in the lungless salamanders: what are the consequences for developmental biology, evolution and phylogenesis?

Direct development is a widespread alternate reproductive mode in living amphibians that is characterized by evolutionary loss of the free-living, aquatic larval stage. Courtship, mating, and oviposition occur on land, and the terrestrial egg hatches as a fully formed, miniature adult. While it is the most common reproductive mode in urodeles, development outside the reproductive tract of the female that proceeds directly to a terrestrial hatchling occurs in only a single lineage, the lungless salamanders of the family Plethodontidae. Evolution of direct development in plethodontids has contributed importantly to the extraordinary evolutionary success of this speciose, geographically widespread, and morphologically and ecologically diverse taxon. Developmental consequences and correlates include increased egg size and embryonic development time, loss of larval structures and ontogenetic repatterning, and altered pattern formation in organogenesis. Evolutionary and phylogenetic consequences and correlates include the loss of larval constraints and origin of morphological novelty, and frequent homoplasy. Analysis of direct development in an evolutionary context illustrates the complex interplay between processes of phylogenetic divergence and developmental biology, and substantiates the prominent role of developmental processes in both constraining phenotypic variation and promoting phenotypic diversity. Despite the proven suitability of direct-developing plethodontid salamanders for laboratory and field study, knowledge of basic features of their developmental biology remains far below that available for many other urodeles. Examination of such features of these "non-model" organisms is an appropriate and deserving goal of future research.

Animals↗

Effect of bottlenecks on incipient sexual isolation, mating activity and fertility in Drosophila malerkotliana.

Effect of bottleneck sizes, on sexual isolation, mating speed and fertility were studied in D. malerkotliana established from natural population. After 10 generations of laboratory breeding, flies showed incipient sexual isolation between control line and some bottleneck lines and also between bottleneck lines. These findings do not fully agree with the general assumption that the establishment of bottlenecks accelerates speciation. The courtship latency and mating speed increases with increasing size of bottlenecks whereas copulation duration and fertility decreases with increasing bottleneck size. There was no sign of rebounding in fitness with in 10 generations as observed by Bryant et al. in house flies.

Animals↗

Dissolution of tradition: a reprise.

Last summer, within the pages of this journal, an essay described the uncertainty surrounding the future of our small but independent VNA ("Dissolution of Tradition into Fantasy: A Lament," May/June, 1996). Supposedly, harsh financial pressures bombarded us and our Board began an inexorable movement toward affiliation with a powerful local hospital. When professional staff became jittery, Board representatives soothed us. This anxious period, given the decidedly unromantic coinage "due diligence," was likened to a courtship phase, an arranged engagement of sorts. Cold feet, second thoughts, panic attacks, and troubled dreams--all were to be expected, considered perfectly natural. All would be forgotten in the bliss of connubial union. Be patient and trust, we were advised; the consummation would make it all worthwhile. And we tried. What has transpired between last summer and this spring, however, exceeded our most vivid nightmare. Betrayed and angry, we scrambled to save what we could of our VNA before it was consigned to obsolescence in this, the year of our centennial.

Community Health Nursing↗

Intimate partner abuse and high-risk behavior in adolescents.

OBJECTIVES: To determine the associations between abuse by an intimate partner and risk behaviors among adolescents and to determine whether these associations vary by gender. DESIGN AND PARTICIPANTS: Ordinal and linear regression analyses of 1996 cross-sectional data from 4347 adolescents surveyed for wave 2 of the National Longitudinal Study of Adolescent Health public use data set. MAIN OUTCOME MEASURES: A 5-point scale was used to measure whether the adolescent had been the victim of any of the following behaviors by an intimate partner: insulted in public, sworn at, threatened with violence, or had something thrown at them. Risk behavior involvement was determined using 5 measures: substance use, antisocial behavior, violent behavior, suicidal behavior, and depressed mood. RESULTS: There was no significant difference in the frequency of abuse by an intimate partner for males (21.0%) vs females (22.1%). In females, after adjusting for sociodemographic factors and number of intimate partners, a history of abuse was significantly associated with substance use (values given as beta, 99% confidence interval) (0.87, 0.51-1.23), antisocial behavior (0.15, 0.10-0.20), violent behavior (0.06, 0.01-0.11), depressed mood (1.82, 1.21-2.43), and suicidal behavior (odds ratio, 1.37, 1.14-1.63). In males, abuse was independently associated with antisocial behavior (0.11, 0.03-0.19), violent behavior (0.09, 0.04-0.14), and depressed mood (1.29, 0.53-2.06). Abuse by an intimate partner had a significantly stronger association with substance use in females (0.87, 0.51-1.23) vs males (0.34, -0.09 to 0.77). CONCLUSIONS: Abuse by an intimate partner is common among adolescents and has strong associations with risk behaviors among male and female victims of abuse.

Adolescent↗

Dating violence against adolescent girls and associated substance use, unhealthy weight control, sexual risk behavior, pregnancy, and suicidality.

CONTEXT: Intimate partner violence against women is a major public health concern. Research among adults has shown that younger age is a consistent risk factor for experiencing and perpetrating intimate partner violence. However, no representative epidemiologic studies of lifetime prevalence of dating violence among adolescents have been conducted. OBJECTIVE: To assess lifetime prevalence of physical and sexual violence from dating partners among adolescent girls and associations of these forms of violence with specific health risks. DESIGN, SETTING, AND PARTICIPANTS: Female 9th through 12th-grade students who participated in the 1997 and 1999 Massachusetts Youth Risk Behavior Surveys (n = 1977 and 2186, respectively). MAIN OUTCOME MEASURES: Lifetime prevalence rates of physical and sexual dating violence and whether such violence is independently associated with substance use, unhealthy weight control, sexual risk behavior, pregnancy, and suicidality. RESULTS: Approximately 1 in 5 female students (20.2% in 1997 and 18.0% in 1999) reported being physically and/or sexually abused by a dating partner. After controlling for the effects of potentially confounding demographics and risk behaviors, data from both surveys indicate that physical and sexual dating violence against adolescent girls is associated with increased risk of substance use (eg, cocaine use for 1997, odds ratio [OR], 4.7; 95% confidence interval [CI], 2.3-9.6; for 1999, OR, 3.4; 95% CI, 1.7-6.7), unhealthy weight control behaviors (eg, use of laxatives and/or vomiting [for 1997, OR, 3.2; 95% CI, 1.8-5.5; for 1999, OR, 3.7; 95% CI, 2.2-6.5]), sexual risk behaviors (eg, first intercourse before age 15 years [for 1997, OR, 8.2; 95% CI, 5.1-13.4; for 1999, OR, 2.4; 95% CI, 1.4-4.2]), pregnancy (for 1997, OR, 6.3; 95% CI, 3.4-11.7; for 1999, OR, 3.9; 95% CI, 1.9-7.8), and suicidality (eg, attempted suicide [for 1997, OR, 7.6; 95% CI, 4.7-12.3; for 1999, OR, 8.6; 95% CI, 5.2-14.4]). CONCLUSION: Dating violence is extremely prevalent among this population, and adolescent girls who report a history of experiencing dating violence are more likely to exhibit other serious health risk behaviors.

Adolescent↗

Romantic love: an fMRI study of a neural mechanism for mate choice.

Scientists have described myriad traits in mammalian and avian species that evolved to attract mates. But the brain mechanisms by which conspecifics become attracted to these traits is largely unknown. Yet mammals and birds express mate preferences and make mate choices, and data suggest that this "attraction system" is associated with the dopaminergic reward system. It has been proposed that intense romantic love, a cross-cultural universal, is a developed form of this attraction system. To determine the neural mechanisms associated with romantic love we used functional magnetic resonance imaging (fMRI) and studied 17 people who were intensely "in love" (Aron et al. [2005] J Neurophysiol 94:327-337). Activation specific to the beloved occurred in the right ventral tegmental area and right caudate nucleus, dopamine-rich areas associated with mammalian reward and motivation. These and other results suggest that dopaminergic reward pathways contribute to the "general arousal" component of romantic love; romantic love is primarily a motivation system, rather than an emotion; this drive is distinct from the sex drive; romantic love changes across time; and romantic love shares biobehavioral similarities with mammalian attraction. We propose that this attraction mechanism evolved to enable individuals to focus their mating energy on specific others, thereby conserving energy and facilitating mate choice-a primary aspect of reproduction. Last, the corticostriate system, with its potential for combining diverse cortical information with reward signals, is an excellent anatomical substrate for the complex factors contributing to romantic love and mate choice.

Adolescent↗

Adolescents' interactions with the opposite sex: influence of attachment style and gender.

The present research assessed attachment style and gender differences in adolescents' relationships with the opposite sex, using questionnaire and diary methodologies. In Study 1, 193 unmarried undergraduate subjects completed questionnaire measures of attachment style, relationship history and attitudes to sex. Relationship history data supported previous findings: avoidant subjects reported fewer and less intense love experiences; anxious/ambivalent subjects reported frequent but less enduring love relationships; secure subjects reported more loving and satisfying relationships. As hypothesized, avoidant subjects were more accepting of casual (uncommitted) sex than other attachment groups. In Study 2, 85 subjects from the previous study used a diary format to record their interactions with members of the opposite sex, classifying each interaction according to intimacy level and partner type. Avoidant subjects engaged in fewer interactions overall, fewer chats, and interacted with a smaller number of friends. Anxious/ambivalent subjects engaged in fewer interactions with strangers than did secure subjects. Female avoidants and male anxious/ambivalents were the least likely to report engaging in sexual intercourse during the course of the study, suggesting that attachment style and gender role expectations jointly influence relationship development.

Adolescent↗

Love and dating experience in early and middle adolescence: grade and gender comparisons.

The experience of being "in love" was studied in a sample of 186 early to middle adolescent males and 199 early to middle adolescent females. Results indicated that amount of dating experience of adolescents varied widely at each age. Being "in love" co-occurred with a reciprocal on-going relationship about half the time. Boys fell in love earlier and more often than girls, and both genders seemed to employ an increasingly narrow prototypical conception of being "in love". Qualitative analyses suggested that early and middle adolescents are actively reasoning about the nature and meaning of romantic feelings and experiences. Results are interpreted from the standpoint of psychosocial developmental theory, and implications for interventions with adolescents are discussed.

Adolescent↗

Cognitive strategies employed in trying to arrange a first date.

This article deals with how adolescents go about making a date. It uses a funnelling approach to elicit information which is then studied in more detail in a series of further steps. Study 1 used a short survey to obtain data concerning subjects' (n=410) experience of dating. Thereafter, 47 of these subjects selected situations and actions relevant to their dating experience, from two specially prepared lists. Study 1 provided information concerning the relevance of the lists, their comprehensibility and the frequency with which subjects had encountered specific situations or actions. In Study 2, 287 subjects completed the survey, 73 were selected and given revised versions of the lists. After selecting situations and actions, they were interviewed concerning their choice. Subject's responses are discussed with respect to social cognitive development in adolescence.

Adolescent↗

Characteristics of closeness in adolescent romantic relationships.

This investigation was designed to describe characteristics of closeness in the romantic relationships of early, mid and late adolescents, and to determine whether adolescent reports of relationship authority and reciprocity are linked to perceptions of interdependence, interaction frequency, activity diversity, influence, and relationship duration. Age was positively associated with interdependence, daily social interaction, weekly activity diversity, and reciprocity but not with influence, authority, or relationship duration; gender was unrelated to all characteristics of closeness. Authority and reciprocity were each positively associated with relationship influence. Authority moderated associations between reciprocity and several characteristics of closeness such that reciprocity was positively linked to interdependence, daily social interaction, and weekly activity diversity, but only in relationships characterized by low levels of authority. Neither reciprocity nor authority was associated with relationship duration.

Adolescent↗

The instability of possible selves: identity processes within late adolescents' close peer relationships.

Understanding how identities emerge and stabilize within the context of interpersonal relationships is an important issue in identity research. Seventy-six late adolescents and their peer partners participated in a laboratory study that focused on the possible selves tied to anticipated career, marriage, and parenthood roles. Control theory (people work to maintain existing identities) and the concept of psychosocial moratorium (identity exploration involves actively "trying on" different selves) were integrated to explain identity construction processes. Consistent with notions of exploration and commitment, emerging self-definitions for highly desired possible selves were unstable. Consistent with control theory, stable self-definitions for anticipated selves occurred when adolescents were committed to avoiding the role. The relationship context mattered only minimally for the adolescents' exploration activities. The behavior of peer partners, however, made it more likely that adolescents would engage in identity exploration of highly important possible selves. The integration of control theory with the concept of psychosocial moratorium offers explanations for the emergence of new identities and their ultimate stabilization.

Adult↗