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Results for “Polystyrenes”

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PubMed1978

Survey of mortality among employees engaged in the manufacture of styrene and polystyrene at the BASF Ludwigshafen works.

A mortality survey of 1,960 employees currently or previously exposed to styrene at work has shown that the observed number of deaths from cancer or other causes is no higher than the number expected in the German population or in a group of BASF employees. Analyses of deaths occurring after a minimum period of five years in groups exposed for different durations (5 years, 10 years, 15 years, more than 15 years) indicated no increase in mortality with exposure time. This latter observation also applied to malignant tumors; therefore it may be inferred that prolonged exposure to styrene is not a cancer hazard.

Adolescent↗
PubMedDate not supplied

[The accelerating action of polystyrene latex on myoblast proliferation in culture].

Latex beads (1800 A) added to chick embryonic muscle cell culture at the moment of plating accelerate and enhance the mitotic activity of myoblasts as soon as by the end of the first day of cultivation. The mitotic index of the induced cultures was several times greater than that characteristic of usual myoblast cultures. The formation of myotubes and the appearance of satellite-like cells was observed during the same period.

Animals↗
PubMed1996

[Structural changes in the cytoskeletal actin in cultured muscle cells when the cultures are stimulated by polystyrene latex].

As we reported elsewhere, the addition of polysterol latex (180 nm) to chick muscle culture accelerated several myogenesis stages, such as proliferation and fusion. In the present work we tried to determine the role of cytoskeletal actin in the mechanism of acceleration. The localization of cytoskeletal actin was studied in normal and latex induced cultures with the help of rodamine--phalloidin. The obtained data have shown that latex beads added to the cultural medium brought about acceleration of cell spreading (the number of spread cell was approximately five times more in comparison with the norm) and enhanced the development of actin network (90% of the cell area was filled with stress-fibrils in 20 h, instead of within 1-3 in the norm). It is proposed that muscle cells interact primarily with latex beads in the cultural medium before seeding on the glass. From this point of view latex beads can be considered as a primary substratum. The cell contact with the primary substratum initiates the actin network reorganization that leads to activation of cell spreading with a subsequent acceleration of myogenesis process: adhesion, proliferation and fusion.

Actins↗