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At least 1,387 records · Page 77Linked to original sources
PubMed2004

[Treatment-resistant granulomatous rosacea-like dermatitis in a 9-year-old girl].

A 9-year-old female developed facial papules and pustules since four years. Clinically, perioral dermatitis was suspected. Different topical therapy regimens and systemic anibiotics had been unsuccessful and a skin biopsy showed granulomatous (lupoid) rosacea. Only systemic antibiotic treatment with minocyclin led to healing of the skin lesions. While granulomatous rosacea-like dermatitis is more frequently diagnosed in adults, it is only rarely encountered in children where, in most of the cases, it represents a therapeutic challenge.

Anti-Bacterial Agents↗
PubMed2005

Efficacy of imidacloprid, imidacloprid/permethrin and phoxim for flea control in the Mustelidae (ferrets, mink).

Farmed mink (Mustela vison), a close relative of the domestic ferret (Mustela putorius furo), naturally infested with the squirrel flea (Ceratophyllus sciurorum) were included in a study to investigate three compounds for flea control. The test products were imidacloprid in a 10% (w/v) solution, an imidacloprid 10% (w/v)/permethrin 50% (w/v) solution, and phoxim; all three are well-known compounds for the control of different ectoparasites in a wide range of animals. Two groups of mink received 0.1 ml per animal of the imidacloprid or the imidacloprid/permethrin combination at days 0 and 28, respectively. Two groups of mink were sprayed with 25 ml of a 0.1% phoxim solution at day 0 and either 1x25 ml or 2x25 ml, respectively, of a 0.05% phoxim solution at day 28. One group of mink served as an untreated control. At assessment on day 56 the efficacy was 91.9% in the imidacloprid group, 89.3% in the imidacloprid/permethrin group, 92.2% in the phoxim 1x25-ml group and 99.3% in the phoxim 2x25 ml group, respectively. In the untreated control group an average of 757 fleas per mink nesting material was recorded.

Administration, Topical↗
PubMed2005

Efficacy of imidacloprid/permethrin and fipronil/(S)-methoprene combinations against Haemaphysalis longicornis ticks evaluated under in vitro and in vivo conditions.

Haemaphysalis longicornis is one of the most important ticks infesting a wide range of mammals including dogs in Japan. H. longicornis is recorded to be a vector of, for example, Babesia gibsoni. It was the aim of the study presented here to evaluate the efficacy of imidacloprid/permethrin and fipronil/(S)-methoprene against larval, nymphal and adult stages of H. longicornis under in vitro as well as in vivo conditions. In the in vitro part of the study, ticks showed avoidance behaviour to imidacloprid/permethrin-treated filter papers. The onset of acaricidal efficacy in the imidacloprid/permethrin group was recorded earlier than in the fipronil/(S)-methoprene group. In the in vivo experiment three beagles per group were treated with either imidacloprid/permethrin, fipronil/(S)-methoprene or left untreated. Each dog was infested with 30 adult female H. longicornis. Ticks were place on a shaved area of skin of the treated dogs and behaviour of the ticks was recorded as before. After 3 h all ticks were removed and placed in Petri dishes. Ticks were further examined until day 4 post-treatment (p.t.). All ticks recovered from the untreated dogs survived. At 4 h p.t. (1 h post-removal) 40 of the 90 ticks exposed to the imidacloprid/permethrin treatment and 25 of the 90 ticks in the fipronil/(S)-methoprene-treated group were found dead. At day 1 p.t., 61 ticks in the imidacloprid/permethrin- and 81 ticks in the fipronil/(S)-methoprene-treated group were recorded dead. At the final examination day 4 p.t., all 90 ticks were found dead in the imidacloprid/permethrin group, while five ticks remained alive in the fipronil/(S)-methoprene group.

Administration, Topical↗
PubMed1991

Trial of pyrethroid impregnated bednets in an area of Tanzania holoendemic for malaria. Part 4. Effects on incidence of malaria infection.

Groups of about 30 children in each of five villages were given pyrimethamine-sulfadoxine to clear their malaria parasitaemia, and they were followed up with fortnightly blood slides. Parasitaemia returned rapidly in the absence of vector control, but more slowly when pyrethroid impregnated nets were in use or the houses had been sprayed with DDT. Variation between the incidence of malaria infection in these cases seemed to depend more on ecological or social factors than on the particular form of vector control adopted.

Bedding and Linens↗
PubMed1986

Sodium depletion in the periaxonal space of the squid axon treated with pyrethroids.

Pyrethroids are known to increase the steady-state sodium current during a step depolarization and to increase and prolong the tail sodium current associated with a step repolarization of the membrane. The pyrethroid-induced tail sodium current of squid axons developed as a function of the duration of the conditioning depolarizing pulse. However, with further lengthening the conditioning pulse duration, it decreased, further increased, or remained constant depending on the direction of sodium current during the depolarization, irrespective of the membrane potential per se. The depletion or accumulation of sodium in the periaxonal space during a 200-ms conditioning depolarizing pulse in the axon internally treated with pronase, pyrethroids, or both, was demonstrated by measurements of the changes in sodium reversal potential. Thus the observed changes in tail current amplitude as a function of the conditioning pulse duration are explicable in terms of changes in sodium concentration in the periaxonal space without assuming inactivation of the pyrethroid-modified channel.

Animals↗
PubMedDate not supplied

Measurement of serum haptoglobin as an indicator of the efficacy of malaria intervention trials.

Serum haptoglobin levels were measured by an enzyme-linked immunosorbent assay in Gambian children who participated in 3 malaria intervention trials with untreated or impregnated bed nets. In one study, in which a significant effect on clinical malaria was observed, the mean serum haptoglobin level was significantly higher in the intervention than in the control group. In the other 2 studies, in which no significant protection was observed, mean haptoglobin levels were similar in intervention and control groups. Measurement of serum haptoglobin may provide a useful indirect measure of the effectiveness of malaria control programmes.

Bedding and Linens↗