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PubMed1993

[The cytotoxicity of Sne-Pack periodontal dressing and scanning electron microscopic study]

We prepare a non-eugenol periodontal dressing Sne-pack(Sp),then investigated the effects of cess cytotxicity and observed the surface of materials on scanning electron of materials on scanning electron microscopy.The comparison results with Coe-pack (Cp) and zinc oxide-eugenol(Ce)showed that three materials have inconsiderable toxic effect on L-929 cell,the Sp and Cp dressing are smoother than Ce.

Journal Article↗
PubMed2004

[Different dressings in surgery].

The presented review of literature gives data on the structure, mechanisms of action and properties of different types of the present-day dressing materials and means for treatment of wounds: sorption, protective, activated with medicines and atraumatic ones. It is shown that medical dressings keep the priority significance in treatment of wounds of different etiology which is due to the effectiveness, availability and simplicity in using them in different conditions.

Alginates↗
PubMed2005

Contact activation and down regulation of neutrophils by cellulose wound dressings can be prevented by radical scavengers.

Neutrophil interaction with wound dressing materials was studied. A meshed non-woven cellulose was chosen as model dressing. Neutrophils isolated from human blood was added to the cellulose, and the production of reactive oxygen species was measured by luminol-amplified chemiluminescence. The respiratory burst response of the neutrophils was found to be activated upon contact with cellulose. The contact activation of the cells increased when the cellulose was oxidised with periodate, and decreased when the cellulose was reduced with cyanoborohydride, indicating that the activation of the respiratory burst response was due to carbonyl-induced stress. The contact activation of the respiratory burst response resulted in an inability of the neutrophils to respond to a secondary stimulation with zymosan. When radical scavenger enzymes were covalently bound to the cellulose, the contact activation was decreased and the ability to respond to stimuli was increased. Addition of the molecular scavenger glutathione (GSH) did not decrease the cell activation upon cellulose contact, but the cell showed an intact ability to respond to secondary stimuli after cellulose contact. In conclusion, the results show that the environmental redox potential effects neutrophils in a situations of clinical interest and that the addition of radical scavengers protects the neutrophils against material-induced damage resulting in preserved cell function.

Bandages↗
PubMed2005

A guide to the properties and uses of silver dressings in wound care.

Silver-release dressings are extensively used for wound management, particularly in the treatment of burns, chronic leg ulcers and wounds requiring an antibacterial. A variety of products is now available. The properties and uses of these dressings are discussed, followed by a review of advances over recent years

Bandages↗
PubMed2005

Effect of different sterile barrier precautions and central venous catheter dressing on the skin colonization around the insertion site.

AIM: The purpose of this prospective, randomized, controlled study was the comparison of maximal sterile barrier (consisting of mask, cap, sterile gloves, gown, large drape) vs control precautions (mask, cap, sterile gloves, small drape) and of transparent polyurethan film vs gauze dressing for use on central venous (CVC) nontunneled catheters, inserted via the jugular vein. Skin colonization at the insertion site (defined by quantitative skin cultures performed at the time of insertion and in days 2 and 5) was used as a primary endpoint. Catheter tip colonization was also assessed through qualitative culture and CVC related sepsis was defined by the isolation of the same organism from the catheter tip and the blood, with clinical sepsis of no other apparent source. METHODS: Eighty-two consecutive patients were enrolled, admitted to a mixed medical-surgical ICU, aged 72+/-12 years, 58% male, SAPS II 42+/-13. One-hundred and seven CVCs were studied (presenting 750 catheter in situ days); CVCs were in place for a mean period of 6.9+/-4.7 days and 5 episodes of central catheter-related bloodstream infection were detected (6.6 per 1000 catheter days). RESULTS: A multiple logistic regression detected an increased risk of skin colonization in male gender (OR=2.5) and control precautions (OR=3.4) and no difference with regard to age, dressing and diagnostic group. CONCLUSIONS: Maximal sterile barrier proved to be an effective and recommended practice. However surveillance skin cultures revealed the common and changing nature of colonization of skin at the insertion site.

Aged↗
PubMed2005

Urgosorb[TM] dressing: management of acute and chronic wounds.

This article illustrates the outcomes of a 10-patient prospective case study series. The aim of the study was to evaluate the use of Urgosorb[TM] in the management of acute and chronic wounds. (Urgosorb[TM] is a dressing comprising calcium alginate fibres and hydrocolloid, and is recommended for sloughy and granulating wounds with moderate to high levels of exudate). Parameters assessed were the effectiveness of exudate management and integrity of surrounding tissue, ease of removal, patient comfort, effectiveness of odour control and observation for any adverse reactions. Data were collected over a period of 6 weeks with weekly evaluations. Healing was not included in the study objectives as it was recognized this would be difficult on a range of highly variable wounds. Although healing was not assessed, 50% of the wounds did heal during the study period. Dressing removal was considered easy in the majority of cases, and patients experienced none, or only mild discomfort. Levels of exudate were well managed and there were no reports of any adverse events.

Journal Article↗
PubMedDate not supplied

Urgosorb dressing: management of acute and chronic wounds.

This article illustrates the outcomes of a 10-patient prospective case study series. The aim of the study was to evaluate the use of Urgosorb in the management of acute and chronic wounds. (Urgosorb is a dressing comprising calcium alginate fibres and hydrocolloid, and is recommended for sloughy and granulating wounds with moderate to high levels of exudate.) Parameters assessed were the effectiveness of exudate management and integrity of surrounding tissue, ease of removal, patient comfort, effectiveness of odour control and observation for any adverse reactions. Data were collected over a period of 6 weeks with weekly evaluations. Healing was not included in the study objectives as it was recognized this would be difficult on a range of highly variable wounds. Although healing was not assessed, 50% of the wounds did heal during the study period. Dressing removal was considered easy in the majority of cases, and patients experienced none, or only mild discomfort. Levels if exudate were well managed and there were no reports of any adverse events.

Acute Disease↗
PubMed2005

[The role of hydrocolloid dressings in the process of debridement and treatment of venous leg ulcers].

Wound debridement is an important cycle of reactions which influences the optimal growth of new cells. It is assumed that the organism has a natural ability to debride and prepare the wound bed for proliferation, usually well enough for wound closure. Nevertheless in cases of venous leg ulcers chronic activity of causal factors may disturb homeosthasis of the micro-environment and modify the cycle of processes. Interventions carried out through systematic debridement should help and facilitate internal healing processes. Ensuring optimal moist wound environment by the use of hydrocoloid dressings facilitate autolysis and optimalize wound micro-environment. The aim of the study was to describe the role of hydrocoloid dressings in the process of debridement and treatment of venous leg ulcers.

Bandages, Hydrocolloid↗
PubMed2006

[How to select and change a dressing].

To minimize pain when changing dressing for peripheral venous catheters, to select the adequate dressing in functions of the circumstances presented by each patient, and to utilize as references the recommendations by Centers for Disease Control and Prevention (CDCs) form the fundamental bases for this article.

Bandages↗
PubMed1995

Wound management: the occlusive dressing.

Superficial wounds resulting from athletic injury are common in sports medicine. Although such wounds can be quite painful, they are usually merely inconvenient to the athlete. If improperly managed, however, superficial wounds may heal slowly and cause unnecessary scar tissue proliferation at the wound site. Scar formation causes the wound to break open frequently and puts the athlete at risk of cross-contamination by pathogenic organisms. New advances in the science of wound management strongly favor the use of occlusive dressings to increase patient comfort, increase patient compliance, decrease the risk of infection, and decrease overall healing time. Occlusion has clearly been proven to aid in the healing of superficial wounds and should be considered as a treatment alternative for wounds in the sports medicine setting. In this paper, I discuss three of the most widely used types of occlusive dressings: 1) films, 2) hydrogels, and 3) hydrocolloids.

Journal Article↗
PubMed2003

Iodine induced thyrotoxicosis following povidine-iodine dressings: a case report.

A 40-year-old woman was admitted to the intensive care unit after a radical resection of a recurrent abdominal malignancy. Her postoperative course was complicated by sepsis requiring numerous abdominal operations with the abdomen being left open for drainage and dressings. Use of povidone-iodine soaked abdominal packs to reduce secondary infection led to development of thyrotoxicosis, which resolved following the cessation of the iodine dressings. A high index of suspicion is needed for the diagnosis of this condition in intensive care patients as the usual haemodynamic signs of thyrotoxicosis may be misinterpreted as being caused by sepsis.

Journal Article↗
PubMed2006

[Multi-center clinical study of acticoat (nanocrystalline silver dressing) for the management of residual burn wounds].

OBJECTIVE: To investigate the clinical efficacy and safety of Acticoat (nanocrystalline silver dressing) for the treatment of residual burn wounds. METHODS: Ninety-eight patients with 166 residual burn wounds were enrolled in the multi-center randomized clinical trials. In addition to the routine treatment, Acticoat was applied onto the wounds of the trial group once a day if there was much exudation from the wound, or the dressing change was made every other two days when the wounds were clean. Silver sulfadiazine (SD-Ag) was used in the control group of patients. The healing time was observed up to 20 days. The healing rate on the 15th day after treatment was taken as the percentage of healing. RESULTS: The average healing time was (12 +/- 5) days after the application of Acticoat, which was significantly shorter than that in control wounds with SD-Ag (16 +/- 6) days, (P = 0.005 < 0.01). The total effective rate of the wounds for trial was 97.05%, which was higher than that in control (94.17%) group, but there was no statistically significant difference. The bacterial clearing rate of the Acticoat group on the 6th and 12th post treatment day was 21.7% and 43.5% respectively, which was significantly higher than that in control group. No side-effect was observed in the two groups during the study. CONCLUSION: Acticoat with nanocrystalline silver can promote the healing of residual burn wounds effectively.

Adolescent↗
PubMedDate not supplied

[Antioxidant activity of inhibitors of free radical reactions in the dressing materials for wound healing].

Antioxidant activity (AA) of inhibitors of free radical reactions (FRR) (dieton, mexidol, trypsin), aplied to the dressing material for wound healing was studied. In our work we used a model system containing suspension of laminated liposome, formed from fraction of total chicken yolk phospholipids. Lipid peroxidation (LPO) of liposome membranes was initiated by addition of Fe2+ ions. The kinetics of FRR was followed by coumarine-enhanced chemiluminescence (CL). It was found that AA of the inhibitors was determined by their ability to intersept aqueous and hydrofobic free radicals and chelate Fe2+ ions. Their ability to intersept radicals reduced in the following order: dieton > trypsin > mexidol. In addition we discovered unknown ability of mexidol to interact with Fe2+, that resulted in elemination of FRR catalyst. Investigating AA of the FRR inhibitors in the two-components mixture, consisting of dieton and mexidol, we observed the effect of multifunctionality: dieton, increased the duration of latent period of CL by intersepting lipid peroxyl radicals, while mexidol, decreased its value by interacting with Fe2+, i.e. mexidol masked the action of dieton. Investigating AA of two-components mixture, consisting of mexidol and trypsine, we observed the same effect of multifunctionality. In the two-component mixture, consisting of trypsine and dieton, the action of the inhibitors was found to be synergistic. All antioxidant properties of these FRR inhibitors were also preserved in the three component mixture. Hence, mixture components, dieton, mexidol and trypsin, possess high AA, that validates their use in dressing materials employed for wound healing.

Antioxidants↗
PubMed2006

Which dressing should I use? It all depends on the 'TIMEING'.

BACKGROUND: Wound management is more than the application of a dressing. It requires a comprehensive and informed approach to the assessment of the patient, their wound and their healing environment OBJECTIVE: This article outlines a systematic approach to guide assessment and management of chronic wounds. DISCUSSION: An international advisory panel has developed a framework for assessment and management of chronic wounds, known as wound bed preparation. The steps in this framework include tissue assessment and the management of nonviable tissue or tissue deficits, inflammation and infection control, maintenance of moisture balance, and the promotion of epithelial advancement of wound edges. The acronym 'TIME' is a useful aid for these steps. In addition, good wound care involves assessment of the surrounding skin and wound dimensions, and documentation of the wound healing process and treatments used. Dressing choice depends on this assessment and the characteristics of the wound. Goals of care include the need to consider the patient, their wound and their healing environment.

Bandages↗
PubMed1991

Women dentists' office apparel: dressing for success in an age of infection control.

A questionnaire on office apparel was answered by 928 of the 2000 women dentists surveyed. The most surprising aspect of this study is that only 51% of all the women surveyed feel the need to wear some type of lab coat or uniform for infection control. Women dentists who do wear a lab coat over street clothes do so primarily for the enhancement of their professional image. Women dentists reporting the highest gross incomes were more likely to wear only street clothes (P = .01) in the office. This study suggests that the dichotomy of dressing for success and dressing for infection control is an issue that needs to be addressed by the profession. Guidelines would be especially helpful for the majority of women dentists who are currently in their first years of practice.

Adult↗
PubMed1991

Clinical experience with a calcium alginate dressing.

Calcium alginate dressings have been used in the treatment of pressure ulcers and leg ulcers. This study analyzes the effectiveness of a calcium alginate dressing in wound exudate absorption, patient comfort, and ease of application.

Adult↗
PubMed1991

Adolescent dress, Part II: A qualitative study of suburban high school students.

Through observation and interviews of high school students, the role of dress in a nonpsychiatric population was explored in order to provide data complementary to the first phase of a larger research project. Adolescent dress was examined in relation to three dimensions of the self: the public, private, and secret self. Due to the age of subjects and the length of contact with the interviewer, results provided most information about the public self, particularly descriptions of social types--categories based on appearance and behavior. These types included a modal, or "average," type and more extreme types including "punks," "freaks," and "nerds." Extreme social types appeared to offer valuable reference points for "average" adolescents in the development of their individual identities.

Adolescent↗