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[Antibiotic prevention with a single dose of metronidazole in appendectomy in children].

One hundred children were prophylactically treated with 15 mg/kg-1 of metronidazole immediately before appendicectomy and retrospectively compared with 100 other patients without any antibioprophylaxis. No statistically significant difference was found between the two groups as regards age, weight, sex and macroscopic appearance of the appendix. The overall incidence of complications was 1% in the antibioprophylactic group and 9% in the control group. Furthermore, a single pre-operative intravenous dose of metronidazole was as effective as conventional antibioprophylaxis.

Appendectomy↗

Psychologic preparation program for children undergoing acute appendectomy.

A psychologic preparation program was developed for use prior to emergency surgery in children. The purpose of this study was to determine whether specific information prior to an emergency operation would reduce anxiety. The effect of the preparation program was evaluated with clinical and laboratory procedures. One group of children who received only general verbal information was compared with another group who received specific information. The subjects were 24 patients and their parents. The children were studied at four different clinical units prior to operation, using the Visual Analogue Scale and pulse rate and blood pressure measurements. Stress hormone levels were measured at three of these clinical units. Visual Analogue Scales were administered to parents three times prior to the child's operation. The results were analyzed for within-group differences from one clinical unit to the next and for between-group differences at the various clinical units. The results indicated less anxiety in the children who received specific information. Catecholamine and beta-endorphin measurements were not greatly different between the groups.

Acute Disease↗

[5th day syndrome after appendectomy. Plea against surgical treatment straight off].

Thirteen cases of post-appendicectomy "fifth day syndrome" (0.45% of 2,919 children operated upon) are reported. The diagnosis must be established on precise criteria. Treatment is primarily medical, using antibiotics and anti-inflammatory drugs, and it must produce rapid and complete results. It is only when it fails (2 cases in our series) that a second operation is justified.

Anti-Bacterial Agents↗