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[Miliary, ganglionar, pancreatic and costal tuberculosis. Clinical presentation and literature review].

A 42-year-old man was admitted to the hospital with fever, abdominal pain and miliary radiological pattern. The amylase and lipase in serum, and the amylase in urine were increased. The tuberculin skin test was negative. The thoracic and abdominal CT scan showed costal affectation, multiple focal hepatic lesions and large necrosing peripancreatic lymphadenopathies. The transbronchial biopsy and the pancreatic punction demonstrated granulomatous necrotic lesions, and M. tuberculosis grew in the bronchial washing culture. The specific treatment normalized the pulmonary, costal and pancreatic lesions.

Adult↗

[Recovery criteria and time in patients with pulmonary tuberculosis].

A new technology of medical service of those followed up at tuberculosis control dispensaries (TCD) was developed on the basis of analysis of the data available in the literature. In doing so, the author took into account the specific features of clinical manifestations of ROT, the pattern and rates of involution of a tuberculous process with current therapeutical and diagnostic capacities borne in mind. This made it possible to define the optimum duration of a basic course of combined treatment in patients with ROT, new principles of evaluation of the outcomes of treatment, criteria for clinical recovery, as well as the procedure and duration of a follow-up. Testing this technology indicated that the latter enhanced the efficiency and profitability of TCD activities by reducing the duration of the basic course of treatment (by an average of 9-11 months), by accelerating the time of statement of ROT recovery (by 1-2 years), by decreasing follow-up periods in control TCD groups (by an average of 3 years), by drastically reducing the number of persons to receive drug therapy for preventive purposes (by 58-70%). Moreover, it may be used extensively in all regions of Russia and requires no additional logistic means and resources.

Adult↗

[The detection rate and clinical and diagnostic values of L forms of the pathogen in patients with pulmonary or extrapulmonary tuberculosis].

The detection rate and clinical and diagnostic values of L-forms of pathogens were determined in patients with pulmonary and extrapulmonary tuberculosis. Simultaneous culturing the specimens for typical and L forms of Mycobacterium tuberculosis (MBT) increased the number of positive results by isolating only L-forms by 10.3% in patients with pulmonary tuberculosis and by 27.7% in those with extrapulmonary tuberculosis. No bacterial isolation in tests only for typical forms of MBT is shown not to be true and a purposeful search for L-forms of MBT enhances the efficiency of a bacteriological test. This is of great significance in confirming the specific nature of the disease, its progression, in choosing a treatment policy, in evaluating is efficiency, in defining prognosis, and in correcting preventive measures in the focus of tuberculous infection. With extrapulmonary tuberculosis, the tuberculous nature of isolated L-forms has been evidenced by the polymerase chain reaction.

Female↗

Tuberculous parotitis.

Tuberculosis, though rare, should be considered in the differential diagnosis of a diffuse swelling of the parotid with enlarged cervical glands, particularly in young, feverish adults.

Adult↗

[Extrathoracic forms of tuberculosis in Mahajanga hospitals (Madagascar)].

Pathological samples issued from patients suspected of extrapulmonary tuberculosis were examined in Laboratories of Mycobacteria and of Histopathology at the Androva Hospital in the University Hospital Centre of Mahajanga. A retrospective study was carried out from 1989 to 1993. During this period, 64 cases of extrapulmonary tuberculosis were recorded. Samples came from Androva Hospital, from Lutherian Hospital of Antanimalandy and from the Medical Centre of Mahabibo. The sex-ratio was of 1.28/1, mean age was 28 years old (extreme ages: 1-78 years old). The diagnosis was confirmed by bacteriological and/or histopathological examinations. Ganglial tuberculosis were the most frequent (53.1%), then digestive tract tuberculosis (20.2%) and anal fistula tuberculosis (14%). In front of chronic lesions, biopsies must be performed to obtain confirmation of diagnosis.

Adolescent↗

[Medicosocial structure and cause of death of patients with tuberculosis].

Tuberculosis mortality rates increased in the Kirov Region during 1990-200, but remained lower than those in Russia. In the past 2 years, the mortality became stable. The sociomedical structure and the causes of death were studied in 62 patients with tuberculosis who had died in the hospital of the Kirov regional tuberculosis dispensary in 2000-2001. An analysis was made among new cases and cases registered at the dispensary. Deaths more commonly occurred in males (83.8%), able-bodied and poor individuals (75.8 and 61.3%, respectively), patients with acutely progressive pulmonary tuberculosis (53.2%), and those with drug resistance (48.4%). Tuberculosis progression was the main cause of death in 53.2%.

Adult↗

[Traps of tuberculosis among the aged: an astonishing cyst of left foot].

We report the case of a 75 years old man who insidiously developed a unusual presentation of tuberculosis. The story began with a tuberculous arthritis of the foot, later associated with pulmonary, endobronchial, mediastinal and cervical lymphadenitis tuberculosis. Because the microscopic examination was negative for acid-fast bacilli (AFB) in all involved sites, the diagnosis of sarcoidosis was suggested. We discuss the diagnosis difficulties of tuberculosis in the elderly, the extrapulmonary manifestations of tuberculosis and some aspects of its differential diagnosis with sarcoidosis.

Aged↗

[Variability and diagnosis of pulmonary tuberculosis].

Five hundred-ninety new cases of tuberculosis were analyzed in Republic Santariskiu Tuberculosis and Lung Disease Hospital during 06 1997-06 2001. Mean age of patients - 47+/-30 years. All cases were classified based on international tuberculosis classification: pulmonary tuberculosis (A15, A16) - 409 cases; tuberculosis pleurisy (A15.6, A16.5) - 169; miliary tuberculosis (A19) - 11; generalized tuberculous lymphadenitis (A18.5) - 1. Pulmonary tuberculosis confirmed by sputum smear (A15.0) was prevalent in the structure of new tuberculosis cases (26.4%); pulmonary tuberculosis was confirmed by culture (A15.1) in 14.1%; by histology (A15.2) - in 10.3%. Unconfirmed pulmonary tuberculosis (A16) and tuberculous pleurisy (A16.5) amounted to 28.5%. Liver biopsy and positive sputum cultures for mycobacterias mostly confirmed tuberculosis diagnosis in miliary tuberculosis cases. From all tuberculous pleurisy cases in 65% the diagnosis was confirmed by bacteriology and/or histology.

Adult↗

[Results of studying of the pathomorphism of pulmonary tuberculosis in Iakutiia].

The paper summarizes the results of studies into the pathological anatomy and pathomorphism of pulmonary tuberculosis in Yakutia, which have been conducted by the Department of Anatomy, Yakutsk State University Medical Institute, over 36 years. A morphological comparative analysis of autopsies of individuals who died from different forms in the pre-antibacterial and antibacterial periods and surgical materials were used as a major source of data. More than 1,000 autopsies made it possible to define a wide range of behavioral patterns and the morphological features of pulmonary tuberculosis under the extreme climatic conditions of the Far North. These findings have made a significant contribution to the development of the new scientific school Northern Phthisiology.

Arctic Regions↗